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The map label for this gene is prsA

Identifier: 57650630

GI number: 57650630

Start: 1950911

End: 1951873

Strand: Direct

Name: prsA

Synonym: SACOL1897

Alternate gene names: 57650630

Gene position: 1950911-1951873 (Clockwise)

Preceding gene: 57650629

Following gene: 57650639

Centisome position: 69.44

GC content: 30.94

Gene sequence:

>963_bases
ATGAAGATGATAAACAAATTAATCGTTCCGGTAACAGCTAGTGCTTTATTATTAGGCGCTTGTGGCGCTAGTGCCACAGA
CTCTAAAGAAAATACATTAATTTCTTCTAAAGCTGGAGACGTAACAGTTGCAGATACAATGAAAAAAATCGGTAAAGATC
AAATTGCAAATGCATCATTTACTGAAATGTTAAATAAAATTTTAGCTGATAAATATAAAAATAAAGTTAATGATAAGAAG
ATTGACGAACAAATTGAAAAAATGCAAAAGCAATACGGCGGTAAAGATAAATTTGAAAAGGCCCTTCAACAGCAAGGTTT
AACAGCCGATAAATATAAAGAAAATTTACGTACTGCTGCTTATCATAAAGAATTACTATCAGATAAAATTAAAATCTCTG
ATTCTGAAATTAAAGAAGACAGCAAGAAAGCTTCACACATTTTAATTAAAGTTAAATCTAAGAAAAGCGACAAAGAAGGC
TTAGATGATAAAGAAGCGAAACAAAAAGCTGAAGAAATTCAAAAAGAAGTTTCAAAAGATCCAAGTAAATTTGGTGAAAT
CGCTAAAAAAGAATCAATGGATACTGGTTCAGCTAAAAAAGATGGCGAATTAGGTTATGTTCTTAAAGGACAAACTGATA
AAGATTTTGAAAAAGCACTATTTAAGCTTAAAGATGGTGAAGTATCAGAGGTTGTTAAATCAAGCTTTGGATATCATATT
ATTAAAGCTGATAAACCAACAGACTTTAACAGTGAAAAACAAAGCCTGAAAGAAAAATTAGTCGATCAGAAAGTACAAAA
AAATCCAAAATTATTGACTGATGCATACAAAGATCTATTAAAAGAATACGATGTTGACTTTAAAGATCGTGATATTAAAT
CAGTTGTCGAAGATAAAATCTTAAACCCTGAAAAACTTAAACAAGGTGGCGCACAAGGCGGACAATCCGGCATGAGCCAA
TAA

Upstream 100 bases:

>100_bases
CTAAACCTAATGCTCTAGTCTGATGTCATGGGTTATTGATTGGTGATAATATAAAACTATGTTATATTCACGATGATTAA
CTTACAAAGGAGTTTCAACT

Downstream 100 bases:

>100_bases
CACAAAACCGAGCGACCGTGGTTCAAAAATCATACCACGGCCGCTCGGTTTTTTCGCATTAAAAATCGGACAGATGAGCT
CATGTTTCAGTATACTCATC

Product: protein export protein PrsA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 320; Mature: 320

Protein sequence:

>320_residues
MKMINKLIVPVTASALLLGACGASATDSKENTLISSKAGDVTVADTMKKIGKDQIANASFTEMLNKILADKYKNKVNDKK
IDEQIEKMQKQYGGKDKFEKALQQQGLTADKYKENLRTAAYHKELLSDKIKISDSEIKEDSKKASHILIKVKSKKSDKEG
LDDKEAKQKAEEIQKEVSKDPSKFGEIAKKESMDTGSAKKDGELGYVLKGQTDKDFEKALFKLKDGEVSEVVKSSFGYHI
IKADKPTDFNSEKQSLKEKLVDQKVQKNPKLLTDAYKDLLKEYDVDFKDRDIKSVVEDKILNPEKLKQGGAQGGQSGMSQ

Sequences:

>Translated_320_residues
MKMINKLIVPVTASALLLGACGASATDSKENTLISSKAGDVTVADTMKKIGKDQIANASFTEMLNKILADKYKNKVNDKK
IDEQIEKMQKQYGGKDKFEKALQQQGLTADKYKENLRTAAYHKELLSDKIKISDSEIKEDSKKASHILIKVKSKKSDKEG
LDDKEAKQKAEEIQKEVSKDPSKFGEIAKKESMDTGSAKKDGELGYVLKGQTDKDFEKALFKLKDGEVSEVVKSSFGYHI
IKADKPTDFNSEKQSLKEKLVDQKVQKNPKLLTDAYKDLLKEYDVDFKDRDIKSVVEDKILNPEKLKQGGAQGGQSGMSQ
>Mature_320_residues
MKMINKLIVPVTASALLLGACGASATDSKENTLISSKAGDVTVADTMKKIGKDQIANASFTEMLNKILADKYKNKVNDKK
IDEQIEKMQKQYGGKDKFEKALQQQGLTADKYKENLRTAAYHKELLSDKIKISDSEIKEDSKKASHILIKVKSKKSDKEG
LDDKEAKQKAEEIQKEVSKDPSKFGEIAKKESMDTGSAKKDGELGYVLKGQTDKDFEKALFKLKDGEVSEVVKSSFGYHI
IKADKPTDFNSEKQSLKEKLVDQKVQKNPKLLTDAYKDLLKEYDVDFKDRDIKSVVEDKILNPEKLKQGGAQGGQSGMSQ

Specific function: Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins

COG id: COG0760

COG function: function code O; Parvulin-like peptidyl-prolyl isomerase

Gene ontology:

Cell location: Cell membrane; Lipid-anchor (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PpiC domain

Homologues:

Organism=Escherichia coli, GI1786238, Length=99, Percent_Identity=35.3535353535354, Blast_Score=65, Evalue=7e-12,

Paralogues:

None

Copy number: 400 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 160 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): PRSA_STAA1 (A7X3U8)

Other databases:

- EMBL:   AP009324
- RefSeq:   YP_001442416.1
- ProteinModelPortal:   A7X3U8
- SMR:   A7X3U8
- STRING:   A7X3U8
- EnsemblBacteria:   EBSTAT00000005163
- GeneID:   5560626
- GenomeReviews:   AP009324_GR
- KEGG:   saw:SAHV_1826
- eggNOG:   COG0760
- GeneTree:   EBGT00050000024806
- HOGENOM:   HBG712792
- OMA:   MLVEYAV
- ProtClustDB:   CLSK885597
- BioCyc:   SAUR418127:SAHV_1826-MONOMER
- HAMAP:   MF_01145
- InterPro:   IPR023059
- InterPro:   IPR000297
- InterPro:   IPR008880

Pfam domain/function: PF00639 Rotamase; SSF109998 Trigger_fac_C_bac

EC number: =5.2.1.8

Molecular weight: Translated: 35638; Mature: 35638

Theoretical pI: Translated: 9.65; Mature: 9.65

Prosite motif: PS01096 PPIC_PPIASE_1; PS50198 PPIC_PPIASE_2; PS51257 PROKAR_LIPOPROTEIN; PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKMINKLIVPVTASALLLGACGASATDSKENTLISSKAGDVTVADTMKKIGKDQIANASF
CCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHCEEECCCCCCHHHHHHHHHHHHHHCCCHH
TEMLNKILADKYKNKVNDKKIDEQIEKMQKQYGGKDKFEKALQQQGLTADKYKENLRTAA
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHHHH
YHKELLSDKIKISDSEIKEDSKKASHILIKVKSKKSDKEGLDDKEAKQKAEEIQKEVSKD
HHHHHHHHHHCCCHHHHHHHHHHHHEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHCC
PSKFGEIAKKESMDTGSAKKDGELGYVLKGQTDKDFEKALFKLKDGEVSEVVKSSFGYHI
HHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHCCCCHHHHHHHHHCCEEE
IKADKPTDFNSEKQSLKEKLVDQKVQKNPKLLTDAYKDLLKEYDVDFKDRDIKSVVEDKI
EECCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHC
LNPEKLKQGGAQGGQSGMSQ
CCHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MKMINKLIVPVTASALLLGACGASATDSKENTLISSKAGDVTVADTMKKIGKDQIANASF
CCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHCEEECCCCCCHHHHHHHHHHHHHHCCCHH
TEMLNKILADKYKNKVNDKKIDEQIEKMQKQYGGKDKFEKALQQQGLTADKYKENLRTAA
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHHHH
YHKELLSDKIKISDSEIKEDSKKASHILIKVKSKKSDKEGLDDKEAKQKAEEIQKEVSKD
HHHHHHHHHHCCCHHHHHHHHHHHHEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHCC
PSKFGEIAKKESMDTGSAKKDGELGYVLKGQTDKDFEKALFKLKDGEVSEVVKSSFGYHI
HHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHCCCCHHHHHHHHHCCEEE
IKADKPTDFNSEKQSLKEKLVDQKVQKNPKLLTDAYKDLLKEYDVDFKDRDIKSVVEDKI
EECCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHC
LNPEKLKQGGAQGGQSGMSQ
CCHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA