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The map label for this gene is hit [H]

Identifier: 57650627

GI number: 57650627

Start: 1948487

End: 1948909

Strand: Direct

Name: hit [H]

Synonym: SACOL1894

Alternate gene names: 57650627

Gene position: 1948487-1948909 (Clockwise)

Preceding gene: 57650624

Following gene: 57650628

Centisome position: 69.36

GC content: 30.5

Gene sequence:

>423_bases
ATGTCAGAAACAATTTTCGGCAAAATTTTAACTGGAGAAATTCCTAGCTTTAAAGTATATGAAGACGATTATGTCTATGC
CTTTTTAGATATATCACAAGTTACTAAAGGACATACGTTATTAATTCCTAAAAAAGCTTCTGCTAATATCTTTGAAACTG
ATGAAGAAACAATGAAACATATCGGTGCAGCATTACCTAAAGTAGCAAATGCTATTAAGCGTGCATTTAATCCTGATGGT
TTAAACATTATTCAAAATAATGGTGAGTTTGCAGATCAATCTGTATTTCATATTCATTTCCACTTAATTCCTCGATACGA
AAATGATATTGATGGATTTGGTTATAAGTGGGAAACACATGAAGACATTTTAGATAACGATGCAAAACAACAAATTGCTG
AACAAATTCAAGCACAATTTTAA

Upstream 100 bases:

>100_bases
TTATAAAATGCTCATATTAAATACACATGTCCTAATATCGAATTTTTAGCGACAATGTTATAATGAATGGTAATACTAGT
TGAAAAGGAGTGTAGTCATC

Downstream 100 bases:

>100_bases
ATGTATGCTTAATCTAAGCTCGAACGGGTATAATATGATTAATATTATAACAATTGCGTTTGAAGTGATAACATCAAGGT
TAGCAATTTTAAACAAAATG

Product: HIT family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 140; Mature: 139

Protein sequence:

>140_residues
MSETIFGKILTGEIPSFKVYEDDYVYAFLDISQVTKGHTLLIPKKASANIFETDEETMKHIGAALPKVANAIKRAFNPDG
LNIIQNNGEFADQSVFHIHFHLIPRYENDIDGFGYKWETHEDILDNDAKQQIAEQIQAQF

Sequences:

>Translated_140_residues
MSETIFGKILTGEIPSFKVYEDDYVYAFLDISQVTKGHTLLIPKKASANIFETDEETMKHIGAALPKVANAIKRAFNPDG
LNIIQNNGEFADQSVFHIHFHLIPRYENDIDGFGYKWETHEDILDNDAKQQIAEQIQAQF
>Mature_139_residues
SETIFGKILTGEIPSFKVYEDDYVYAFLDISQVTKGHTLLIPKKASANIFETDEETMKHIGAALPKVANAIKRAFNPDGL
NIIQNNGEFADQSVFHIHFHLIPRYENDIDGFGYKWETHEDILDNDAKQQIAEQIQAQF

Specific function: Unknown

COG id: COG0537

COG function: function code FGR; Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HIT domain [H]

Homologues:

Organism=Homo sapiens, GI4885413, Length=105, Percent_Identity=37.1428571428571, Blast_Score=64, Evalue=4e-11,
Organism=Homo sapiens, GI14211923, Length=102, Percent_Identity=32.3529411764706, Blast_Score=64, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17506713, Length=105, Percent_Identity=35.2380952380952, Blast_Score=66, Evalue=6e-12,
Organism=Saccharomyces cerevisiae, GI6320078, Length=128, Percent_Identity=39.84375, Blast_Score=93, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24581222, Length=104, Percent_Identity=37.5, Blast_Score=70, Evalue=6e-13,
Organism=Drosophila melanogaster, GI28574010, Length=104, Percent_Identity=37.5, Blast_Score=70, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011146
- InterPro:   IPR011151
- InterPro:   IPR019808
- InterPro:   IPR001310 [H]

Pfam domain/function: PF01230 HIT [H]

EC number: NA

Molecular weight: Translated: 15945; Mature: 15814

Theoretical pI: Translated: 4.66; Mature: 4.66

Prosite motif: PS00892 HIT_1 ; PS51084 HIT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
0.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSETIFGKILTGEIPSFKVYEDDYVYAFLDISQVTKGHTLLIPKKASANIFETDEETMKH
CCCCCEEEEEECCCCCEEEECCCEEEEEEEHHHHCCCCEEEEECCCCCCEEECCHHHHHH
IGAALPKVANAIKRAFNPDGLNIIQNNGEFADQSVFHIHFHLIPRYENDIDGFGYKWETH
HHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCEEEEEEEEEEECCCCCCCCCCEECCCH
EDILDNDAKQQIAEQIQAQF
HHHHCCHHHHHHHHHHHCCC
>Mature Secondary Structure 
SETIFGKILTGEIPSFKVYEDDYVYAFLDISQVTKGHTLLIPKKASANIFETDEETMKH
CCCCEEEEEECCCCCEEEECCCEEEEEEEHHHHCCCCEEEEECCCCCCEEECCHHHHHH
IGAALPKVANAIKRAFNPDGLNIIQNNGEFADQSVFHIHFHLIPRYENDIDGFGYKWETH
HHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCEEEEEEEEEEECCCCCCCCCCEECCCH
EDILDNDAKQQIAEQIQAQF
HHHHCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377 [H]