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The map label for this gene is engA

Identifier: 57650430

GI number: 57650430

Start: 1553727

End: 1555037

Strand: Reverse

Name: engA

Synonym: SACOL1515

Alternate gene names: 57650430

Gene position: 1555037-1553727 (Counterclockwise)

Preceding gene: 57650431

Following gene: 57650429

Centisome position: 55.35

GC content: 35.24

Gene sequence:

>1311_bases
ATGACTAAACCTATAGTAGCTATTGTAGGTAGGCCTAATGTAGGTAAATCTACAATTTTTAATAGAATAGTTGGAGAACG
TGTTTCGATTGTGGAAGACACGCCAGGTGTAACACGAGATCGTATTTATTCTTCAGGTGAATGGTTAACACATGATTTCA
ATATTATTGATACAGGTGGTATTGAAATTGGTGATGCACCATTCCAAACACAAATTAGAGCGCAGGCAGAAATCGCCATA
GATGAAGCGGATGTTATTATTTTTATGGTTAACGTGCGTGAAGGATTGACACAAAGCGATGAAATGGTCGCTCAAATTTT
ATACAAATCTAAAAAACCGGTCGTATTAGCGGTTAACAAAGTAGATAATATGGAAATGCGTACAGACGTGTATGATTTCT
ATTCATTAGGATTTGGTGAACCGTATCCGATATCAGGGTCACATGGTTTAGGTCTTGGTGACTTGTTAGATGCAGTTGTT
TCTCATTTTGGTGAAGAGGAAGAAGATCCTTATGATGAAGATACAATTCGACTATCCATTATTGGACGACCAAACGTAGG
TAAATCAAGTTTAGTAAATGCTATTTTAGGTGAAGATCGCGTTATCGTTTCTAATGTTGCAGGGACAACGAGAGACGCTA
TTGATACAGAGTATAGTTATGATGGACAAGATTATGTTTTAATCGATACTGCTGGTATGCGTAAAAAAGGAAAAGTATAT
GAATCAACTGAGAAATATTCAGTATTAAGAGCTTTAAAAGCGATTGAACGTTCAAATGTTGTTTTAGTGGTCATAGATGC
AGAACAAGGCATCATTGAACAAGATAAACGTGTTGCAGGATATGCACATGAACAAGGTAAAGCAGTCGTGATTGTCGTAA
ATAAATGGGATACTGTGGAAAAAGATAGTAAAACGATGAAGAAATTTGAAGATGAAGTACGTAAAGAATTCCAATTTTTA
GATTATGCACAAATTGCTTTTGTGTCTGCTAAAGAACGCACAAGATTACGTACATTATTCCCTTACATCAATGAAGCAAG
TGAAAACCATAAAAAACGTGTTCAAAGTTCAACTTTAAATGAAGTTGTTACTGATGCAATTTCCATGAACCCTACACCAA
CAGACAAAGGTAGACGTTTGAATGTCTTTTATGCAACACAAGTTGCTATAGAACCACCGACATTTGTTGTATTTGTTAAT
GATGTAGAATTAATGCATTTTTCTTATAAACGCTATTTAGAGAATCAAATCCGTGCCGCTTTTGGTTTTGAAGGTACACC
AATTCATATTATAGCTCGAAAGAGAAATTAA

Upstream 100 bases:

>100_bases
TTAAGTGCTGATTTTTATCATTACAGTAATAAACTCATTTTGAATACACAGTCTCATGTGATATTATTAAAAAGATATAA
GAAAGAGAGGAAGTTAGCTT

Downstream 100 bases:

>100_bases
CGATTGGGGGATAACAATGACTAAAATTACCGTTTTTGGTATGGGAAGTTTTGGGACAGCCCTTGCCAATGTTCTTGCAG
AAAATGGACATGATGTTTTG

Product: GTP-binding protein EngA

Products: NA

Alternate protein names: GTP-binding protein EngA

Number of amino acids: Translated: 436; Mature: 435

Protein sequence:

>436_residues
MTKPIVAIVGRPNVGKSTIFNRIVGERVSIVEDTPGVTRDRIYSSGEWLTHDFNIIDTGGIEIGDAPFQTQIRAQAEIAI
DEADVIIFMVNVREGLTQSDEMVAQILYKSKKPVVLAVNKVDNMEMRTDVYDFYSLGFGEPYPISGSHGLGLGDLLDAVV
SHFGEEEEDPYDEDTIRLSIIGRPNVGKSSLVNAILGEDRVIVSNVAGTTRDAIDTEYSYDGQDYVLIDTAGMRKKGKVY
ESTEKYSVLRALKAIERSNVVLVVIDAEQGIIEQDKRVAGYAHEQGKAVVIVVNKWDTVEKDSKTMKKFEDEVRKEFQFL
DYAQIAFVSAKERTRLRTLFPYINEASENHKKRVQSSTLNEVVTDAISMNPTPTDKGRRLNVFYATQVAIEPPTFVVFVN
DVELMHFSYKRYLENQIRAAFGFEGTPIHIIARKRN

Sequences:

>Translated_436_residues
MTKPIVAIVGRPNVGKSTIFNRIVGERVSIVEDTPGVTRDRIYSSGEWLTHDFNIIDTGGIEIGDAPFQTQIRAQAEIAI
DEADVIIFMVNVREGLTQSDEMVAQILYKSKKPVVLAVNKVDNMEMRTDVYDFYSLGFGEPYPISGSHGLGLGDLLDAVV
SHFGEEEEDPYDEDTIRLSIIGRPNVGKSSLVNAILGEDRVIVSNVAGTTRDAIDTEYSYDGQDYVLIDTAGMRKKGKVY
ESTEKYSVLRALKAIERSNVVLVVIDAEQGIIEQDKRVAGYAHEQGKAVVIVVNKWDTVEKDSKTMKKFEDEVRKEFQFL
DYAQIAFVSAKERTRLRTLFPYINEASENHKKRVQSSTLNEVVTDAISMNPTPTDKGRRLNVFYATQVAIEPPTFVVFVN
DVELMHFSYKRYLENQIRAAFGFEGTPIHIIARKRN
>Mature_435_residues
TKPIVAIVGRPNVGKSTIFNRIVGERVSIVEDTPGVTRDRIYSSGEWLTHDFNIIDTGGIEIGDAPFQTQIRAQAEIAID
EADVIIFMVNVREGLTQSDEMVAQILYKSKKPVVLAVNKVDNMEMRTDVYDFYSLGFGEPYPISGSHGLGLGDLLDAVVS
HFGEEEEDPYDEDTIRLSIIGRPNVGKSSLVNAILGEDRVIVSNVAGTTRDAIDTEYSYDGQDYVLIDTAGMRKKGKVYE
STEKYSVLRALKAIERSNVVLVVIDAEQGIIEQDKRVAGYAHEQGKAVVIVVNKWDTVEKDSKTMKKFEDEVRKEFQFLD
YAQIAFVSAKERTRLRTLFPYINEASENHKKRVQSSTLNEVVTDAISMNPTPTDKGRRLNVFYATQVAIEPPTFVVFVND
VELMHFSYKRYLENQIRAAFGFEGTPIHIIARKRN

Specific function: GTPase that plays an essential role in the late steps of ribosome biogenesis

COG id: COG1160

COG function: function code R; Predicted GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH-like domain

Homologues:

Organism=Escherichia coli, GI87082120, Length=455, Percent_Identity=42.1978021978022, Blast_Score=351, Evalue=4e-98,
Organism=Escherichia coli, GI1788919, Length=179, Percent_Identity=34.0782122905028, Blast_Score=86, Evalue=5e-18,
Organism=Escherichia coli, GI2367268, Length=112, Percent_Identity=37.5, Blast_Score=74, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17507259, Length=87, Percent_Identity=40.2298850574713, Blast_Score=66, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6323665, Length=208, Percent_Identity=31.25, Blast_Score=87, Evalue=5e-18,
Organism=Drosophila melanogaster, GI45550813, Length=179, Percent_Identity=32.9608938547486, Blast_Score=80, Evalue=4e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DER_STAA1 (A7X2I1)

Other databases:

- EMBL:   AP009324
- RefSeq:   YP_001442053.1
- ProteinModelPortal:   A7X2I1
- SMR:   A7X2I1
- STRING:   A7X2I1
- EnsemblBacteria:   EBSTAT00000005002
- GeneID:   5560201
- GenomeReviews:   AP009324_GR
- KEGG:   saw:SAHV_1463
- eggNOG:   COG1160
- GeneTree:   EBGT00050000024727
- HOGENOM:   HBG592135
- OMA:   TRDRTYQ
- ProtClustDB:   PRK00093
- BioCyc:   SAUR418127:SAHV_1463-MONOMER
- GO:   GO:0005622
- HAMAP:   MF_00195
- InterPro:   IPR016484
- InterPro:   IPR006073
- InterPro:   IPR015946
- InterPro:   IPR002917
- InterPro:   IPR005225
- Gene3D:   G3DSA:3.30.300.20
- PIRSF:   PIRSF006485
- PRINTS:   PR00326
- TIGRFAMs:   TIGR03594
- TIGRFAMs:   TIGR00231

Pfam domain/function: PF01926 MMR_HSR1

EC number: NA

Molecular weight: Translated: 48980; Mature: 48849

Theoretical pI: Translated: 5.00; Mature: 5.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKPIVAIVGRPNVGKSTIFNRIVGERVSIVEDTPGVTRDRIYSSGEWLTHDFNIIDTGG
CCCCEEEEECCCCCCHHHHHHHHHCCCEEEEECCCCCCHHHEECCCCEEEEECEEEECCC
IEIGDAPFQTQIRAQAEIAIDEADVIIFMVNVREGLTQSDEMVAQILYKSKKPVVLAVNK
EEECCCCCHHHEEEEEEEEEECCCEEEEEEECCCCCCCHHHHHHHHHHCCCCCEEEEEEC
VDNMEMRTDVYDFYSLGFGEPYPISGSHGLGLGDLLDAVVSHFGEEEEDPYDEDTIRLSI
CCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCEEEEEE
IGRPNVGKSSLVNAILGEDRVIVSNVAGTTRDAIDTEYSYDGQDYVLIDTAGMRKKGKVY
EECCCCCHHHHHHHHHCCCEEEEEECCCCCHHHCCCCCCCCCCCEEEEECCCCCCCCCCH
ESTEKYSVLRALKAIERSNVVLVVIDAEQGIIEQDKRVAGYAHEQGKAVVIVVNKWDTVE
HHHHHHHHHHHHHHHHCCCEEEEEEECCCCCHHCCCHHHCEEECCCCEEEEEEECCCCCC
KDSKTMKKFEDEVRKEFQFLDYAQIAFVSAKERTRLRTLFPYINEASENHKKRVQSSTLN
HHHHHHHHHHHHHHHHHHHCCHHHEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EVVTDAISMNPTPTDKGRRLNVFYATQVAIEPPTFVVFVNDVELMHFSYKRYLENQIRAA
HHHHHHHCCCCCCCCCCCEEEEEEEEEEEECCCEEEEEECCEEEHHHHHHHHHHHHHHHH
FGFEGTPIHIIARKRN
CCCCCCCEEEEEECCC
>Mature Secondary Structure 
TKPIVAIVGRPNVGKSTIFNRIVGERVSIVEDTPGVTRDRIYSSGEWLTHDFNIIDTGG
CCCEEEEECCCCCCHHHHHHHHHCCCEEEEECCCCCCHHHEECCCCEEEEECEEEECCC
IEIGDAPFQTQIRAQAEIAIDEADVIIFMVNVREGLTQSDEMVAQILYKSKKPVVLAVNK
EEECCCCCHHHEEEEEEEEEECCCEEEEEEECCCCCCCHHHHHHHHHHCCCCCEEEEEEC
VDNMEMRTDVYDFYSLGFGEPYPISGSHGLGLGDLLDAVVSHFGEEEEDPYDEDTIRLSI
CCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCEEEEEE
IGRPNVGKSSLVNAILGEDRVIVSNVAGTTRDAIDTEYSYDGQDYVLIDTAGMRKKGKVY
EECCCCCHHHHHHHHHCCCEEEEEECCCCCHHHCCCCCCCCCCCEEEEECCCCCCCCCCH
ESTEKYSVLRALKAIERSNVVLVVIDAEQGIIEQDKRVAGYAHEQGKAVVIVVNKWDTVE
HHHHHHHHHHHHHHHHCCCEEEEEEECCCCCHHCCCHHHCEEECCCCEEEEEEECCCCCC
KDSKTMKKFEDEVRKEFQFLDYAQIAFVSAKERTRLRTLFPYINEASENHKKRVQSSTLN
HHHHHHHHHHHHHHHHHHHCCHHHEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EVVTDAISMNPTPTDKGRRLNVFYATQVAIEPPTFVVFVNDVELMHFSYKRYLENQIRAA
HHHHHHHCCCCCCCCCCCEEEEEEEEEEEECCCEEEEEECCEEEHHHHHHHHHHHHHHHH
FGFEGTPIHIIARKRN
CCCCCCCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA