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The map label for this gene is recU

Identifier: 57650404

GI number: 57650404

Start: 1527594

End: 1528220

Strand: Direct

Name: recU

Synonym: SACOL1489

Alternate gene names: 57650404

Gene position: 1527594-1528220 (Clockwise)

Preceding gene: 57650403

Following gene: 57650405

Centisome position: 54.37

GC content: 32.06

Gene sequence:

>627_bases
ATGAATTATCCAAATGGTAAACCATATCGTAAAAATAGTGCTATAGACGGAGGGAAAAAGACCGCTGCCTTTAGTAATAT
TGAGTATGGTGGACGTGGTATGTCACTTGAAAAAGATATCGAACATTCAAATACGTTTTATCTTAAAAGCGACATTGCAG
TTATTCACAAAAAGCCTACGCCAGTACAAATAGTTAATGTCAACTATCCTAAGCGGAGTAAAGCTGTGATTAACGAAGCT
TATTTTCGTACACCTTCAACAACTGATTACAACGGCGTTTATCAAGGTTATTATATTGATTTTGAAGCAAAGGAAACTAA
AAACAAGACGTCCTTTCCTTTAAATAATATTCATGACCATCAAGTCGAACATATGAAAAATGCATATCAACAAAAAGGTA
TTGTGTTTTTAATGATTCGTTTTAAAACGCTAGATGAAGTTTATCTTTTACCCTATTCAAAATTCGAAGTATTTTGGAAG
AGATATAAAGATAATATTAAAAAGTCTATAACAGTTGATGAAATACGAAAAAATGGTTACCATATTCCTTATCAGTATCA
ACCAAGATTAGACTATCTAAAAGCAGTTGATAAGTTGATATTAGATGAAAGTGAGGACCGCGTATGA

Upstream 100 bases:

>100_bases
TATTGTGTCTTTCGCATTTATACTAATTTAAGTTTGGTGTTTCACTATAATGTTGTGTATAATAAACAACGTTTACTACC
AAACTTGTGTGGTGAAATTT

Downstream 100 bases:

>100_bases
CGGAAAACAAAGGATCTTCTCAGCCTAAGAAAAACGGTAATAATGGTGGGAAATCCAACTCAAAAAAGAATAGAAATGTG
AAGAGAACGATTATTAAGAT

Product: Holliday junction-specific endonuclease

Products: NA

Alternate protein names: Recombination protein U homolog

Number of amino acids: Translated: 208; Mature: 208

Protein sequence:

>208_residues
MNYPNGKPYRKNSAIDGGKKTAAFSNIEYGGRGMSLEKDIEHSNTFYLKSDIAVIHKKPTPVQIVNVNYPKRSKAVINEA
YFRTPSTTDYNGVYQGYYIDFEAKETKNKTSFPLNNIHDHQVEHMKNAYQQKGIVFLMIRFKTLDEVYLLPYSKFEVFWK
RYKDNIKKSITVDEIRKNGYHIPYQYQPRLDYLKAVDKLILDESEDRV

Sequences:

>Translated_208_residues
MNYPNGKPYRKNSAIDGGKKTAAFSNIEYGGRGMSLEKDIEHSNTFYLKSDIAVIHKKPTPVQIVNVNYPKRSKAVINEA
YFRTPSTTDYNGVYQGYYIDFEAKETKNKTSFPLNNIHDHQVEHMKNAYQQKGIVFLMIRFKTLDEVYLLPYSKFEVFWK
RYKDNIKKSITVDEIRKNGYHIPYQYQPRLDYLKAVDKLILDESEDRV
>Mature_208_residues
MNYPNGKPYRKNSAIDGGKKTAAFSNIEYGGRGMSLEKDIEHSNTFYLKSDIAVIHKKPTPVQIVNVNYPKRSKAVINEA
YFRTPSTTDYNGVYQGYYIDFEAKETKNKTSFPLNNIHDHQVEHMKNAYQQKGIVFLMIRFKTLDEVYLLPYSKFEVFWK
RYKDNIKKSITVDEIRKNGYHIPYQYQPRLDYLKAVDKLILDESEDRV

Specific function: Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair

COG id: COG3331

COG function: function code R; Penicillin-binding protein-related factor A, putative recombinase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the recU family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RECU_STAA1 (A7X2E3)

Other databases:

- EMBL:   AP009324
- RefSeq:   YP_001442027.1
- ProteinModelPortal:   A7X2E3
- SMR:   A7X2E3
- STRING:   A7X2E3
- EnsemblBacteria:   EBSTAT00000004675
- GeneID:   5561496
- GenomeReviews:   AP009324_GR
- KEGG:   saw:SAHV_1437
- eggNOG:   COG3331
- GeneTree:   EBGT00050000025163
- HOGENOM:   HBG571967
- OMA:   GHYIDFE
- ProtClustDB:   PRK02234
- BioCyc:   SAUR418127:SAHV_1437-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00130
- InterPro:   IPR004612
- InterPro:   IPR011335
- PIRSF:   PIRSF037785
- TIGRFAMs:   TIGR00648

Pfam domain/function: PF03838 RecU; SSF52980 Restrict_endonuc_II-like_core

EC number: NA

Molecular weight: Translated: 24444; Mature: 24444

Theoretical pI: Translated: 9.71; Mature: 9.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNYPNGKPYRKNSAIDGGKKTAAFSNIEYGGRGMSLEKDIEHSNTFYLKSDIAVIHKKPT
CCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCHHHCCCCCCEEEEECCEEEEECCCC
PVQIVNVNYPKRSKAVINEAYFRTPSTTDYNGVYQGYYIDFEAKETKNKTSFPLNNIHDH
CEEEEECCCCCHHHHHHHHHHCCCCCCCCCCCEEEEEEEEEECCCCCCCCCCCCCCCCHH
QVEHMKNAYQQKGIVFLMIRFKTLDEVYLLPYSKFEVFWKRYKDNIKKSITVDEIRKNGY
HHHHHHHHHHHCCEEEEEEEECCCCCEEECCCHHHHHHHHHHHHHHHHCCCHHHHHHCCC
HIPYQYQPRLDYLKAVDKLILDESEDRV
CCCEEECCCHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MNYPNGKPYRKNSAIDGGKKTAAFSNIEYGGRGMSLEKDIEHSNTFYLKSDIAVIHKKPT
CCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCHHHCCCCCCEEEEECCEEEEECCCC
PVQIVNVNYPKRSKAVINEAYFRTPSTTDYNGVYQGYYIDFEAKETKNKTSFPLNNIHDH
CEEEEECCCCCHHHHHHHHHHCCCCCCCCCCCEEEEEEEEEECCCCCCCCCCCCCCCCHH
QVEHMKNAYQQKGIVFLMIRFKTLDEVYLLPYSKFEVFWKRYKDNIKKSITVDEIRKNGY
HHHHHHHHHHHCCEEEEEEEECCCCCEEECCCHHHHHHHHHHHHHHHHCCCHHHHHHCCC
HIPYQYQPRLDYLKAVDKLILDESEDRV
CCCEEECCCHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA