Click here to switch to the map view.

The map label for this gene is ps201 [H]

Identifier: 57650158

GI number: 57650158

Start: 903491

End: 904711

Strand: Reverse

Name: ps201 [H]

Synonym: SACOL0885

Alternate gene names: 57650158

Gene position: 904711-903491 (Counterclockwise)

Preceding gene: 57650159

Following gene: 57650149

Centisome position: 32.2

GC content: 32.1

Gene sequence:

>1221_bases
ATGTGGTTAGAAAAATTTAAAAATAAGAATAAAGAAACTAAATATAGATATTACGAGAAGTACAAAGACCCTCTCACTGC
CAAATGGAGACGTGTTAGCGTGGTACTTAATAAGAATGGTAAGCAATCACAAAAAGAAGCTCAAAGACTCTTAAATGAGC
GTATAGAAGCAAAACTGAATGATAAGACACCTACTACACTTAAGTCACTAACTTTCCATGTCGCATGTGATGAGTGGTTT
CAGAGTTATATCAAAACGTCTGGGTCAAAAAGAACAACTATTAAAACTAAATTGAGTAAGCTAAACACTTTGAAGAAATT
TGTAGATGAAGATATTTTAATCAATAAAATAACACTTTCATATGCGCAACAAGTTTTCGATGAAATGGATAATAAAGGTT
ATGTATATCAAGTAAACAAAGATGCGTTAAGCATATTCAAAAATGTATTTGAATACACTAGACGTATCTATAAACTGCAA
GATTTAGAATTTTTAAAAGATATAACGTTAAATAAAAGAATTAAGTCTTATGATGAAGTGAAAGCTAAACGTAATAAGTA
CCTCGAATTAAATGAAATACAATCTATCATCAAAGATATTAATACGAAGGCTCAGAAGATGCACTCAGGTATCCATAAGC
GGTTTTATTTATTCGTTGCACTCATGACAGAATTCCAAGCCTTAAATGGTATGCGTATTGGTGAAATGTTAGCCATTCAA
AATGAAGATATAGACTTTGATAATAAGAGTTTAAATATTAACGGAACAATCCATTGGTTTCACGATGAATCTGGTGGATT
CGGTGTAAAAGATACCACTAAAACAGAGTCTAGTTATAGAACAATTGGATTGAGTAGCAGAAGTTGCGAGATATTAAAGA
AAGCAATACTGGAGAACAAAAAGGATTCAAAATGGAATGATGGATATCTAAATAGAAATTTTGTATTTACTAATCATAAA
GGCAACCCAATGCAGACTGAAAGATTCAATAAAATCCTTAGGGAAGCAGCTAAAGATGTTGGTATTGATAAAGAAGTTTC
TTCACATATATTAAGACATAGCCACATATCATTACTCTCTCAACAAGGCGTGTCACTTAAAGCTATTATGGATCGTGTAG
GCCATTCCGACCACCGTACAACACTTTCCATTTATTCTCACGTTACTGAACAGATGGATAAGGATATGATGAACAAACTT
GAACAGGTAAAACTTGGATAA

Upstream 100 bases:

>100_bases
GAAACGATATAAATCTATTAATTATATTATAATCATTATTTTTCGGGTAGCCCGCCTACCCTTATTATTTTTTTGCCAAT
TTTGAGGAGGGATAAGCAAA

Downstream 100 bases:

>100_bases
TGCGCTCAAATCTGAGCGTATTTTTTGTTTGAAATTCGATAATTTGCATATACCGCCCCTTTTGCGCCCTTTTTTTATTT
TCAATACCACAAAAATAACC

Product: pathogenicity island protein, integrase

Products: NA

Alternate protein names: Int-TnX [H]

Number of amino acids: Translated: 406; Mature: 406

Protein sequence:

>406_residues
MWLEKFKNKNKETKYRYYEKYKDPLTAKWRRVSVVLNKNGKQSQKEAQRLLNERIEAKLNDKTPTTLKSLTFHVACDEWF
QSYIKTSGSKRTTIKTKLSKLNTLKKFVDEDILINKITLSYAQQVFDEMDNKGYVYQVNKDALSIFKNVFEYTRRIYKLQ
DLEFLKDITLNKRIKSYDEVKAKRNKYLELNEIQSIIKDINTKAQKMHSGIHKRFYLFVALMTEFQALNGMRIGEMLAIQ
NEDIDFDNKSLNINGTIHWFHDESGGFGVKDTTKTESSYRTIGLSSRSCEILKKAILENKKDSKWNDGYLNRNFVFTNHK
GNPMQTERFNKILREAAKDVGIDKEVSSHILRHSHISLLSQQGVSLKAIMDRVGHSDHRTTLSIYSHVTEQMDKDMMNKL
EQVKLG

Sequences:

>Translated_406_residues
MWLEKFKNKNKETKYRYYEKYKDPLTAKWRRVSVVLNKNGKQSQKEAQRLLNERIEAKLNDKTPTTLKSLTFHVACDEWF
QSYIKTSGSKRTTIKTKLSKLNTLKKFVDEDILINKITLSYAQQVFDEMDNKGYVYQVNKDALSIFKNVFEYTRRIYKLQ
DLEFLKDITLNKRIKSYDEVKAKRNKYLELNEIQSIIKDINTKAQKMHSGIHKRFYLFVALMTEFQALNGMRIGEMLAIQ
NEDIDFDNKSLNINGTIHWFHDESGGFGVKDTTKTESSYRTIGLSSRSCEILKKAILENKKDSKWNDGYLNRNFVFTNHK
GNPMQTERFNKILREAAKDVGIDKEVSSHILRHSHISLLSQQGVSLKAIMDRVGHSDHRTTLSIYSHVTEQMDKDMMNKL
EQVKLG
>Mature_406_residues
MWLEKFKNKNKETKYRYYEKYKDPLTAKWRRVSVVLNKNGKQSQKEAQRLLNERIEAKLNDKTPTTLKSLTFHVACDEWF
QSYIKTSGSKRTTIKTKLSKLNTLKKFVDEDILINKITLSYAQQVFDEMDNKGYVYQVNKDALSIFKNVFEYTRRIYKLQ
DLEFLKDITLNKRIKSYDEVKAKRNKYLELNEIQSIIKDINTKAQKMHSGIHKRFYLFVALMTEFQALNGMRIGEMLAIQ
NEDIDFDNKSLNINGTIHWFHDESGGFGVKDTTKTESSYRTIGLSSRSCEILKKAILENKKDSKWNDGYLNRNFVFTNHK
GNPMQTERFNKILREAAKDVGIDKEVSSHILRHSHISLLSQQGVSLKAIMDRVGHSDHRTTLSIYSHVTEQMDKDMMNKL
EQVKLG

Specific function: Fimb Is One Of The 2 Regulatory Proteins Which Control The Phase Variation Of Type 1 Fimbriae In E. coli. These Proteins Mediate The Periodic Inversion Of A 300bp DNA Segment That Harbors The Promoter For The Fimbrial Structural Gene, Fima. Fimb Switches

COG id: COG0582

COG function: function code L; Integrase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR023109 [H]

Pfam domain/function: PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 47587; Mature: 47587

Theoretical pI: Translated: 10.15; Mature: 10.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MWLEKFKNKNKETKYRYYEKYKDPLTAKWRRVSVVLNKNGKQSQKEAQRLLNERIEAKLN
CCCHHHCCCCCCHHHHHHHHHCCCHHHCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHCC
DKTPTTLKSLTFHVACDEWFQSYIKTSGSKRTTIKTKLSKLNTLKKFVDEDILINKITLS
CCCCHHHHHHHHEEHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
YAQQVFDEMDNKGYVYQVNKDALSIFKNVFEYTRRIYKLQDLEFLKDITLNKRIKSYDEV
HHHHHHHHHCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KAKRNKYLELNEIQSIIKDINTKAQKMHSGIHKRFYLFVALMTEFQALNGMRIGEMLAIQ
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHEEEEC
NEDIDFDNKSLNINGTIHWFHDESGGFGVKDTTKTESSYRTIGLSSRSCEILKKAILENK
CCCCCCCCCEEEECEEEEEEECCCCCCCCCCCCCCCCCCEEECCCCHHHHHHHHHHHCCC
KDSKWNDGYLNRNFVFTNHKGNPMQTERFNKILREAAKDVGIDKEVSSHILRHSHISLLS
CCCCCCCCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
QQGVSLKAIMDRVGHSDHRTTLSIYSHVTEQMDKDMMNKLEQVKLG
HCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MWLEKFKNKNKETKYRYYEKYKDPLTAKWRRVSVVLNKNGKQSQKEAQRLLNERIEAKLN
CCCHHHCCCCCCHHHHHHHHHCCCHHHCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHCC
DKTPTTLKSLTFHVACDEWFQSYIKTSGSKRTTIKTKLSKLNTLKKFVDEDILINKITLS
CCCCHHHHHHHHEEHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
YAQQVFDEMDNKGYVYQVNKDALSIFKNVFEYTRRIYKLQDLEFLKDITLNKRIKSYDEV
HHHHHHHHHCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KAKRNKYLELNEIQSIIKDINTKAQKMHSGIHKRFYLFVALMTEFQALNGMRIGEMLAIQ
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHEEEEC
NEDIDFDNKSLNINGTIHWFHDESGGFGVKDTTKTESSYRTIGLSSRSCEILKKAILENK
CCCCCCCCCEEEECEEEEEEECCCCCCCCCCCCCCCCCCEEECCCCHHHHHHHHHHHCCC
KDSKWNDGYLNRNFVFTNHKGNPMQTERFNKILREAAKDVGIDKEVSSHILRHSHISLLS
CCCCCCCCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
QQGVSLKAIMDRVGHSDHRTTLSIYSHVTEQMDKDMMNKLEQVKLG
HCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10532372; 11337471 [H]