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The map label for this gene is fucA

Identifier: 41410291

GI number: 41410291

Start: 4663160

End: 4663813

Strand: Reverse

Name: fucA

Synonym: MAP4193c

Alternate gene names: 41410291

Gene position: 4663813-4663160 (Counterclockwise)

Preceding gene: 41410292

Following gene: 41410289

Centisome position: 96.56

GC content: 69.88

Gene sequence:

>654_bases
ATGAAGTTCGTCGACGACCCGGAACAGGCGGTGCTGGACGCCGCCAAGGACATGCTGCGCCGCGGCCTGGTGGAGGGCAC
CGCCGGCAACATCTCGGCGCGCCGCTCCGACGGCAACATCGTCATCACGCCGTCGTCGGTGGACTACCGCGACATGCAGC
TCGACGACCTGGTGCTGATCGACCCCGCCGGTTCGGTGCTGCAGGCCGCGCAGGGCCGCTCGCCGTCCACGGAGATGCAG
CTGCACCTGGCCTGCTTCGCCGCGTTCGACGACATCGGCTGCGTCATCCACAGCCATCCGGTGTGGGCGACCATGTTCGC
CATTGCGCACCAATCGATTCCGGCGTGCATCGACGAGTTCGCGGTGTATTGCGGCGGCGACGTGCGCTGCGCCGACTACG
CCGCCTCCGGCACCCCTGACGTCGGCGCCAACGCGGTCAAGGCGCTGCAGGGCCGCGGCGCCGCCCTGATCGCCAACCAC
GGCCTGGTGGCGGTGGGCCCGCGGCCCGACAAGGTCCTGCACATCACCGCGCTGGTGGAGCGGACCGCCCAAATCGTCTG
GGGCGCAAGAGCTCTCGGCGGTCCGGTGCCAATTCCCGCGGACGTCAACCGCAACTTCGCCGCCGTGTACGGCTATCTGC
GCGCCAACCCCTGA

Upstream 100 bases:

>100_bases
ACACTGAGGCCCGGCAGGCGCAGCTGGTGGCCGACGACCTGGAAGCGCTGCTGGCCGGCGCGACGCCCGCCCACATCGTC
AACCCGGAGGTGTTGGCCCG

Downstream 100 bases:

>100_bases
CGCCTCGGATCCCGGGGCGCGCTGGGCTAACGCTGGTCGAACGCCACCTTCACCGCGCCGGTCCGGCCCTGGTCGGCCAG
GGCGTGGAACGCGTCGCGCC

Product: L-fuculose-phosphate aldolase

Products: NA

Alternate protein names: L-fuculose-1-phosphate aldolase [H]

Number of amino acids: Translated: 217; Mature: 217

Protein sequence:

>217_residues
MKFVDDPEQAVLDAAKDMLRRGLVEGTAGNISARRSDGNIVITPSSVDYRDMQLDDLVLIDPAGSVLQAAQGRSPSTEMQ
LHLACFAAFDDIGCVIHSHPVWATMFAIAHQSIPACIDEFAVYCGGDVRCADYAASGTPDVGANAVKALQGRGAALIANH
GLVAVGPRPDKVLHITALVERTAQIVWGARALGGPVPIPADVNRNFAAVYGYLRANP

Sequences:

>Translated_217_residues
MKFVDDPEQAVLDAAKDMLRRGLVEGTAGNISARRSDGNIVITPSSVDYRDMQLDDLVLIDPAGSVLQAAQGRSPSTEMQ
LHLACFAAFDDIGCVIHSHPVWATMFAIAHQSIPACIDEFAVYCGGDVRCADYAASGTPDVGANAVKALQGRGAALIANH
GLVAVGPRPDKVLHITALVERTAQIVWGARALGGPVPIPADVNRNFAAVYGYLRANP
>Mature_217_residues
MKFVDDPEQAVLDAAKDMLRRGLVEGTAGNISARRSDGNIVITPSSVDYRDMQLDDLVLIDPAGSVLQAAQGRSPSTEMQ
LHLACFAAFDDIGCVIHSHPVWATMFAIAHQSIPACIDEFAVYCGGDVRCADYAASGTPDVGANAVKALQGRGAALIANH
GLVAVGPRPDKVLHITALVERTAQIVWGARALGGPVPIPADVNRNFAAVYGYLRANP

Specific function: Fucose metabolism; third step. [C]

COG id: COG0235

COG function: function code G; Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldolase class II family. AraD/FucA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789164, Length=193, Percent_Identity=34.7150259067358, Blast_Score=119, Evalue=1e-28,
Organism=Escherichia coli, GI1790642, Length=198, Percent_Identity=29.7979797979798, Blast_Score=85, Evalue=4e-18,
Organism=Escherichia coli, GI1786247, Length=210, Percent_Identity=30, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI1790008, Length=190, Percent_Identity=27.8947368421053, Blast_Score=66, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001303
- InterPro:   IPR004782 [H]

Pfam domain/function: PF00596 Aldolase_II [H]

EC number: =4.1.2.17 [H]

Molecular weight: Translated: 22873; Mature: 22873

Theoretical pI: Translated: 5.54; Mature: 5.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFVDDPEQAVLDAAKDMLRRGLVEGTAGNISARRSDGNIVITPSSVDYRDMQLDDLVLI
CCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCEEEECCCCCCCCCCCCCEEEE
DPAGSVLQAAQGRSPSTEMQLHLACFAAFDDIGCVIHSHPVWATMFAIAHQSIPACIDEF
CCCCHHHHHHCCCCCCHHHEEEHHHHHHHHHCCEEEECCCHHHHHHHHHHHHHHHHHHHH
AVYCGGDVRCADYAASGTPDVGANAVKALQGRGAALIANHGLVAVGPRPDKVLHITALVE
HHHCCCCEEEECCCCCCCCCCCHHHHHHHHCCCEEEEECCCEEEECCCCCCEEEHHHHHH
RTAQIVWGARALGGPVPIPADVNRNFAAVYGYLRANP
HHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEEEECCC
>Mature Secondary Structure
MKFVDDPEQAVLDAAKDMLRRGLVEGTAGNISARRSDGNIVITPSSVDYRDMQLDDLVLI
CCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCEEEECCCCCCCCCCCCCEEEE
DPAGSVLQAAQGRSPSTEMQLHLACFAAFDDIGCVIHSHPVWATMFAIAHQSIPACIDEF
CCCCHHHHHHCCCCCCHHHEEEHHHHHHHHHCCEEEECCCHHHHHHHHHHHHHHHHHHHH
AVYCGGDVRCADYAASGTPDVGANAVKALQGRGAALIANHGLVAVGPRPDKVLHITALVE
HHHCCCCEEEECCCCCCCCCCCHHHHHHHHCCCEEEEECCCEEEECCCCCCEEEHHHHHH
RTAQIVWGARALGGPVPIPADVNRNFAAVYGYLRANP
HHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]