The gene/protein map for NC_002944 is currently unavailable.
Definition Mycobacterium avium subsp. paratuberculosis K-10, complete genome.
Accession NC_002944
Length 4,829,781

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The map label for this gene is acr1 [H]

Identifier: 41410141

GI number: 41410141

Start: 4503058

End: 4503954

Strand: Reverse

Name: acr1 [H]

Synonym: MAP4043c

Alternate gene names: 41410141

Gene position: 4503954-4503058 (Counterclockwise)

Preceding gene: 41410142

Following gene: 41410140

Centisome position: 93.25

GC content: 71.91

Gene sequence:

>897_bases
GTGAGCAAGAGTCCGCTTCGCCGGTTCGCCGACCAGTTGGTGCTGGCCACAATGCGACCGCCCATGGCCCCGCAGGTGCT
GGTCAACCGGCCGCTGATCAAGCCGGTCGAGCTGGCCGGCAAGCGCGTGCTGCTCACCGGCGCCTCGTCGGGGATCGGCG
AGGCGGCGGCCGAACAGTTCGCCCGCGAGGGCGCCCGGGTGGTCGTCGTCGCCCGCCGCAAGGACCTGCTGGACGCGCTG
GCCGAGCGCATCACCCGGGCCGGCGGCGAGGCCATCGCGATGCCCTGCGACATCTCCGACCTGGACGCCGCCGACGCGCT
GGTGGCCGACGTACAACAGCGGCTCGGCGGCGTCGACATCCTGATCAACAACGCCGGCCGGTCCATCCGCCGCCCGCTGG
CCGAGTCGCTGGAACGCTGGCACGACGTCGAGCGGACCATGGTGCTCAACTACTACGCGCCGTTGCGGCTGATCCGCGGC
ATCGCCCCGGGCATGATCGAGCGCGGCGACGGCCACATCATCAACGTCTCGACGTGGGGGGTGCTCTCGGAAGCCTCGCC
GCTGTTCGCGGTCTACAACGCTTCCAAGGCCGCGCTGTCCACCGTCAGCCGGGTCGTCGAAACCGAGTGGGGCGACAAGG
GGGTGCACTCCAGCACGCTGTACTACCCGCTGGTGGCCACCCCGATGATCGCGCCGACCAAGGCCTACCAGGGGGTGCCG
GCGCTGACGCCGGAGGAGGCGGGCCGGTGGATGATCACCGCCGCGCGCACCCGGCCGGTGCGCATCGCCCCGCGGATGGC
GATCGCCGCCAAGGCGCTGGACACCTTCGGCCCGCGCTGGGTCAACGCCGTCATGCAGCGCCAGACCGTCCAGCCCAACC
GCGAAGCCGGGGCCTGA

Upstream 100 bases:

>100_bases
CGAGCGTCACGCTGGCGTGACGCTCGGCGGCGCGCGTCACGCTGGCGTGACGCTCGGCTCCGTACGGGCCTCACGGCGGC
GCCGCCTAGACTCGCGTCCC

Downstream 100 bases:

>100_bases
TTCGACGCGTGTGATAGACACGAGGCTATGGAGATCCTGGCCAGCCGGATGCTGCTCCGGCCGGCGGACTATCAGCAGTC
GTTGACGTTCTACCGCGACC

Product: short chain dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 298; Mature: 297

Protein sequence:

>298_residues
MSKSPLRRFADQLVLATMRPPMAPQVLVNRPLIKPVELAGKRVLLTGASSGIGEAAAEQFAREGARVVVVARRKDLLDAL
AERITRAGGEAIAMPCDISDLDAADALVADVQQRLGGVDILINNAGRSIRRPLAESLERWHDVERTMVLNYYAPLRLIRG
IAPGMIERGDGHIINVSTWGVLSEASPLFAVYNASKAALSTVSRVVETEWGDKGVHSSTLYYPLVATPMIAPTKAYQGVP
ALTPEEAGRWMITAARTRPVRIAPRMAIAAKALDTFGPRWVNAVMQRQTVQPNREAGA

Sequences:

>Translated_298_residues
MSKSPLRRFADQLVLATMRPPMAPQVLVNRPLIKPVELAGKRVLLTGASSGIGEAAAEQFAREGARVVVVARRKDLLDAL
AERITRAGGEAIAMPCDISDLDAADALVADVQQRLGGVDILINNAGRSIRRPLAESLERWHDVERTMVLNYYAPLRLIRG
IAPGMIERGDGHIINVSTWGVLSEASPLFAVYNASKAALSTVSRVVETEWGDKGVHSSTLYYPLVATPMIAPTKAYQGVP
ALTPEEAGRWMITAARTRPVRIAPRMAIAAKALDTFGPRWVNAVMQRQTVQPNREAGA
>Mature_297_residues
SKSPLRRFADQLVLATMRPPMAPQVLVNRPLIKPVELAGKRVLLTGASSGIGEAAAEQFAREGARVVVVARRKDLLDALA
ERITRAGGEAIAMPCDISDLDAADALVADVQQRLGGVDILINNAGRSIRRPLAESLERWHDVERTMVLNYYAPLRLIRGI
APGMIERGDGHIINVSTWGVLSEASPLFAVYNASKAALSTVSRVVETEWGDKGVHSSTLYYPLVATPMIAPTKAYQGVPA
LTPEEAGRWMITAARTRPVRIAPRMAIAAKALDTFGPRWVNAVMQRQTVQPNREAGA

Specific function: Catalyzes the NADPH-dependent reduction of long chain acyl-CoA to the corresponding aldehyde [H]

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI7706318, Length=179, Percent_Identity=36.3128491620112, Blast_Score=90, Evalue=3e-18,
Organism=Homo sapiens, GI7705855, Length=200, Percent_Identity=29, Blast_Score=87, Evalue=3e-17,
Organism=Homo sapiens, GI4503817, Length=212, Percent_Identity=33.4905660377358, Blast_Score=86, Evalue=5e-17,
Organism=Homo sapiens, GI20149619, Length=164, Percent_Identity=34.7560975609756, Blast_Score=85, Evalue=8e-17,
Organism=Homo sapiens, GI226371731, Length=212, Percent_Identity=26.8867924528302, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI32483357, Length=197, Percent_Identity=29.9492385786802, Blast_Score=82, Evalue=4e-16,
Organism=Homo sapiens, GI32455239, Length=207, Percent_Identity=30.4347826086957, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI5031765, Length=207, Percent_Identity=30.4347826086957, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI7705925, Length=193, Percent_Identity=32.6424870466321, Blast_Score=79, Evalue=5e-15,
Organism=Homo sapiens, GI126723191, Length=192, Percent_Identity=29.6875, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI40807363, Length=254, Percent_Identity=27.1653543307087, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI7657478, Length=166, Percent_Identity=37.3493975903614, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI5031737, Length=209, Percent_Identity=28.2296650717703, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI109715829, Length=230, Percent_Identity=31.304347826087, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI210032110, Length=261, Percent_Identity=25.6704980842912, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI33667109, Length=194, Percent_Identity=28.8659793814433, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI4557649, Length=178, Percent_Identity=27.5280898876405, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI25282469, Length=294, Percent_Identity=26.1904761904762, Blast_Score=67, Evalue=3e-11,
Organism=Escherichia coli, GI1787820, Length=217, Percent_Identity=29.9539170506912, Blast_Score=82, Evalue=5e-17,
Organism=Escherichia coli, GI1790717, Length=219, Percent_Identity=27.3972602739726, Blast_Score=82, Evalue=6e-17,
Organism=Escherichia coli, GI1787905, Length=141, Percent_Identity=35.4609929078014, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI87082100, Length=226, Percent_Identity=28.7610619469027, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1789378, Length=180, Percent_Identity=32.2222222222222, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1787335, Length=197, Percent_Identity=28.4263959390863, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1789208, Length=236, Percent_Identity=26.271186440678, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI87082160, Length=203, Percent_Identity=29.064039408867, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1786701, Length=183, Percent_Identity=30.6010928961749, Blast_Score=63, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17560150, Length=197, Percent_Identity=29.9492385786802, Blast_Score=92, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17538480, Length=221, Percent_Identity=28.5067873303167, Blast_Score=90, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17563726, Length=221, Percent_Identity=28.0542986425339, Blast_Score=90, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17562990, Length=226, Percent_Identity=27.8761061946903, Blast_Score=90, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17564282, Length=259, Percent_Identity=28.1853281853282, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17562906, Length=222, Percent_Identity=28.8288288288288, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17544670, Length=205, Percent_Identity=34.6341463414634, Blast_Score=86, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI193204405, Length=172, Percent_Identity=32.5581395348837, Blast_Score=86, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17562904, Length=236, Percent_Identity=25.4237288135593, Blast_Score=85, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI17559104, Length=230, Percent_Identity=28.695652173913, Blast_Score=81, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI72000259, Length=192, Percent_Identity=30.2083333333333, Blast_Score=81, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI17562908, Length=248, Percent_Identity=27.0161290322581, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17551412, Length=205, Percent_Identity=28.780487804878, Blast_Score=79, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17560220, Length=175, Percent_Identity=30.8571428571429, Blast_Score=78, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI17567345, Length=218, Percent_Identity=29.8165137614679, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17562910, Length=241, Percent_Identity=28.2157676348548, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17565030, Length=215, Percent_Identity=29.3023255813954, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17508895, Length=213, Percent_Identity=28.169014084507, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17538486, Length=192, Percent_Identity=26.5625, Blast_Score=75, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17560332, Length=203, Percent_Identity=26.6009852216749, Blast_Score=74, Evalue=9e-14,
Organism=Caenorhabditis elegans, GI25152911, Length=209, Percent_Identity=29.1866028708134, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI115534694, Length=196, Percent_Identity=27.5510204081633, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI71982365, Length=149, Percent_Identity=30.8724832214765, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI193203117, Length=151, Percent_Identity=28.476821192053, Blast_Score=68, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI71997099, Length=181, Percent_Identity=32.0441988950276, Blast_Score=68, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI17531453, Length=184, Percent_Identity=29.8913043478261, Blast_Score=67, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI193203115, Length=139, Percent_Identity=29.4964028776978, Blast_Score=65, Evalue=3e-11,
Organism=Drosophila melanogaster, GI21358495, Length=191, Percent_Identity=36.6492146596859, Blast_Score=101, Evalue=5e-22,
Organism=Drosophila melanogaster, GI21357041, Length=194, Percent_Identity=32.4742268041237, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24584744, Length=224, Percent_Identity=28.5714285714286, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI28574402, Length=224, Percent_Identity=28.5714285714286, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24640442, Length=219, Percent_Identity=28.7671232876712, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI116007236, Length=227, Percent_Identity=29.0748898678414, Blast_Score=75, Evalue=4e-14,
Organism=Drosophila melanogaster, GI28571526, Length=180, Percent_Identity=33.3333333333333, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24640492, Length=255, Percent_Identity=23.5294117647059, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI23397609, Length=196, Percent_Identity=31.6326530612245, Blast_Score=73, Evalue=3e-13,
Organism=Drosophila melanogaster, GI21356301, Length=201, Percent_Identity=29.8507462686567, Blast_Score=73, Evalue=3e-13,
Organism=Drosophila melanogaster, GI161076933, Length=212, Percent_Identity=27.3584905660377, Blast_Score=72, Evalue=6e-13,
Organism=Drosophila melanogaster, GI24584748, Length=212, Percent_Identity=27.3584905660377, Blast_Score=72, Evalue=6e-13,
Organism=Drosophila melanogaster, GI281364892, Length=231, Percent_Identity=25.1082251082251, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24644339, Length=183, Percent_Identity=32.7868852459016, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24580925, Length=170, Percent_Identity=33.5294117647059, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24639444, Length=198, Percent_Identity=30.8080808080808, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI116007238, Length=178, Percent_Identity=30.8988764044944, Blast_Score=69, Evalue=5e-12,
Organism=Drosophila melanogaster, GI116007234, Length=212, Percent_Identity=29.2452830188679, Blast_Score=68, Evalue=8e-12,
Organism=Drosophila melanogaster, GI21357673, Length=201, Percent_Identity=27.363184079602, Blast_Score=68, Evalue=9e-12,
Organism=Drosophila melanogaster, GI116007232, Length=84, Percent_Identity=44.047619047619, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI28571387, Length=230, Percent_Identity=30, Blast_Score=66, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24643142, Length=193, Percent_Identity=29.5336787564767, Blast_Score=65, Evalue=7e-11,

Paralogues:

None

Copy number: 1300 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 32273; Mature: 32142

Theoretical pI: Translated: 10.34; Mature: 10.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure: 

>Translated Secondary Structure
MSKSPLRRFADQLVLATMRPPMAPQVLVNRPLIKPVELAGKRVLLTGASSGIGEAAAEQF
CCCCHHHHHHHHHHHHHCCCCCCCHHHHCCCCCCHHHHCCCEEEEECCCCCCCHHHHHHH
AREGARVVVVARRKDLLDALAERITRAGGEAIAMPCDISDLDAADALVADVQQRLGGVDI
HHCCCEEEEEECHHHHHHHHHHHHHHCCCCEEEECCCCCCCCHHHHHHHHHHHHHCCEEE
LINNAGRSIRRPLAESLERWHDVERTMVLNYYAPLRLIRGIAPGMIERGDGHIINVSTWG
EEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCEEEEECCC
VLSEASPLFAVYNASKAALSTVSRVVETEWGDKGVHSSTLYYPLVATPMIAPTKAYQGVP
CCCCCCCEEEEECCHHHHHHHHHHHHHHCCCCCCCCCCEEEEHHHHCCCCCCHHHHCCCC
ALTPEEAGRWMITAARTRPVRIAPRMAIAAKALDTFGPRWVNAVMQRQTVQPNREAGA
CCCHHHCCCEEEEECCCCCEEECCHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
SKSPLRRFADQLVLATMRPPMAPQVLVNRPLIKPVELAGKRVLLTGASSGIGEAAAEQF
CCCHHHHHHHHHHHHHCCCCCCCHHHHCCCCCCHHHHCCCEEEEECCCCCCCHHHHHHH
AREGARVVVVARRKDLLDALAERITRAGGEAIAMPCDISDLDAADALVADVQQRLGGVDI
HHCCCEEEEEECHHHHHHHHHHHHHHCCCCEEEECCCCCCCCHHHHHHHHHHHHHCCEEE
LINNAGRSIRRPLAESLERWHDVERTMVLNYYAPLRLIRGIAPGMIERGDGHIINVSTWG
EEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCEEEEECCC
VLSEASPLFAVYNASKAALSTVSRVVETEWGDKGVHSSTLYYPLVATPMIAPTKAYQGVP
CCCCCCCEEEEECCHHHHHHHHHHHHHHCCCCCCCCCCEEEEHHHHCCCCCCHHHHCCCC
ALTPEEAGRWMITAARTRPVRIAPRMAIAAKALDTFGPRWVNAVMQRQTVQPNREAGA
CCCHHHCCCEEEEECCCCCEEECCHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA