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The map label for this gene is por [H]

Identifier: 41409907

GI number: 41409907

Start: 4256240

End: 4257643

Strand: Reverse

Name: por [H]

Synonym: MAP3809c

Alternate gene names: 41409907

Gene position: 4257643-4256240 (Counterclockwise)

Preceding gene: 41409908

Following gene: 41409906

Centisome position: 88.15

GC content: 68.45

Gene sequence:

>1404_bases
GTGAAGCTGAACGCACATAACCTGACCGGTCTCAAAATCCCCGTCCCGACCTATGACCGTAGCCAAATCGGCATCGGCAT
AGCGCATTTCGGCGTCGGGGGTTTTCATCGTGCCCACCAGGCCATGTATCTGGACCGCTTGCTGAACGACGGTCTCGCCC
GGGACTGGGGCATCTGCGGTATCGGCGTGCTGCCCGACGACCGGCGCATGCGCGACGCGCTGCGCAGCCAGGACTACCTC
TACACGCTGATCCTGGAACATCCCGACGGCACCCAGGAGCCGCGCGTCATCGGATCCATCGTCGACTTCCGTTACGCGCC
TGAGGATCCCGGTTCCGTCGTCGATCTGCTGGCCGATCCCGCCACCCGGATCATCTCGCTCACCATCACCGAGGGCGGCT
ACCAGCCGCCGCTCAGCGCGGCGTTCGAGTTGGTGGCCGAGGCGCTGAATCGGCGACGGGAGCGTGGCCTGCCCTCTCCG
ACGATCGTCTCCTGCGACAACATCATCAAAAACGGAGACGTGGCCCGGCGCGCCTTCACTGCCCACGCCGAGCAGGTCAA
TCCCGAACTCGCGCAATGGATACGGGAGAACACCACCTTCCCCAACTCGATGGTCGACCGGATCACCCCGACGCCCACAC
CAGACCTCGTCGACCGGTTGGCCGCCGAGTTCGGCGTGCAGGACGCCGAGCCGGTGGTGGCCGAGCCGTTCGCCATGTGG
GTGCTCGAGGACGACTTCGCCGACGGGCGGCCCCCGCTGGACAAGGCCGGCGTGCGGCTGGTCGACGACGTGGCGCCCTA
CGAGGCGATCAAGCTGCGGCTGCTCAACGCCGGCCATCAAGGCCTGTGCTATTTCGCCTACCTGGCCGGATACCGCGAGG
TGCACGAGGCCGCGCAGGATCCGGTGATCGCGGAATTCCTTGCCCGCTACATGGATTCGGAGGCGATGCCGACGCTGCCG
CGGATGCCCGGCCTGGAAGACTTCCGCGACGGCCTCATCCCCCGCTTCGCCAACGCCTATGTGGGCGACCAGGTGGCCCG
GCTGTGCGCGGACTCCTCCGACCACATCCCGAAGTGGCTGTTGCCGGTGGTGCACGACAACCTGCGCTCCGGCGGCCCGG
TGCAGCTGTCCGCGGCGATCGTCGCGAGCTGGGCTCGCTACGCCGAGGGCGTCGACGAACAGGGCCGCCCGATCGAGGTG
GTGGACCGGCTCGCCGACACCCTGGTGCCGCTCGCCCGCTCGCAGCGCGAGAATCCGGACGCGTTTCTGGCCAACCGTGC
CGTGTTCGGCGACCTGATCGACGCACCGCGCTTCCGCGAGGCCTACCGGTGGGCCCTGGACTCGCTGCACCGGCGCGGCG
CGCGCGCGACGTTGCGGGCGCTGATCGGGGCCGACGGGTCGTGA

Upstream 100 bases:

>100_bases
GCGGACGTGGTGATCTTCGCGTTGCGCGATCTGTGCCCCAACGCCTAGCACCGGCCCGGTCGCGACCCAGGCGTCCGGTC
CAGGCTAGGGTGACAGTCGA

Downstream 100 bases:

>100_bases
GCCTGGTCGCGGGCATCGACCCGGGCACGGACCCCGCGGCCTGACCTAGGCTGGACGGGGAACAGCCAAAGACATGGACG
CACAGGGCTATTGCGCGCGG

Product: hypothetical protein

Products: D-fructose; NADH; H+

Alternate protein names: NA

Number of amino acids: Translated: 467; Mature: 467

Protein sequence:

>467_residues
MKLNAHNLTGLKIPVPTYDRSQIGIGIAHFGVGGFHRAHQAMYLDRLLNDGLARDWGICGIGVLPDDRRMRDALRSQDYL
YTLILEHPDGTQEPRVIGSIVDFRYAPEDPGSVVDLLADPATRIISLTITEGGYQPPLSAAFELVAEALNRRRERGLPSP
TIVSCDNIIKNGDVARRAFTAHAEQVNPELAQWIRENTTFPNSMVDRITPTPTPDLVDRLAAEFGVQDAEPVVAEPFAMW
VLEDDFADGRPPLDKAGVRLVDDVAPYEAIKLRLLNAGHQGLCYFAYLAGYREVHEAAQDPVIAEFLARYMDSEAMPTLP
RMPGLEDFRDGLIPRFANAYVGDQVARLCADSSDHIPKWLLPVVHDNLRSGGPVQLSAAIVASWARYAEGVDEQGRPIEV
VDRLADTLVPLARSQRENPDAFLANRAVFGDLIDAPRFREAYRWALDSLHRRGARATLRALIGADGS

Sequences:

>Translated_467_residues
MKLNAHNLTGLKIPVPTYDRSQIGIGIAHFGVGGFHRAHQAMYLDRLLNDGLARDWGICGIGVLPDDRRMRDALRSQDYL
YTLILEHPDGTQEPRVIGSIVDFRYAPEDPGSVVDLLADPATRIISLTITEGGYQPPLSAAFELVAEALNRRRERGLPSP
TIVSCDNIIKNGDVARRAFTAHAEQVNPELAQWIRENTTFPNSMVDRITPTPTPDLVDRLAAEFGVQDAEPVVAEPFAMW
VLEDDFADGRPPLDKAGVRLVDDVAPYEAIKLRLLNAGHQGLCYFAYLAGYREVHEAAQDPVIAEFLARYMDSEAMPTLP
RMPGLEDFRDGLIPRFANAYVGDQVARLCADSSDHIPKWLLPVVHDNLRSGGPVQLSAAIVASWARYAEGVDEQGRPIEV
VDRLADTLVPLARSQRENPDAFLANRAVFGDLIDAPRFREAYRWALDSLHRRGARATLRALIGADGS
>Mature_467_residues
MKLNAHNLTGLKIPVPTYDRSQIGIGIAHFGVGGFHRAHQAMYLDRLLNDGLARDWGICGIGVLPDDRRMRDALRSQDYL
YTLILEHPDGTQEPRVIGSIVDFRYAPEDPGSVVDLLADPATRIISLTITEGGYQPPLSAAFELVAEALNRRRERGLPSP
TIVSCDNIIKNGDVARRAFTAHAEQVNPELAQWIRENTTFPNSMVDRITPTPTPDLVDRLAAEFGVQDAEPVVAEPFAMW
VLEDDFADGRPPLDKAGVRLVDDVAPYEAIKLRLLNAGHQGLCYFAYLAGYREVHEAAQDPVIAEFLARYMDSEAMPTLP
RMPGLEDFRDGLIPRFANAYVGDQVARLCADSSDHIPKWLLPVVHDNLRSGGPVQLSAAIVASWARYAEGVDEQGRPIEV
VDRLADTLVPLARSQRENPDAFLANRAVFGDLIDAPRFREAYRWALDSLHRRGARATLRALIGADGS

Specific function: Unknown

COG id: COG0246

COG function: function code G; Mannitol-1-phosphate/altronate dehydrogenases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mannitol dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1788497, Length=473, Percent_Identity=37.4207188160677, Blast_Score=293, Evalue=2e-80,
Organism=Escherichia coli, GI1790779, Length=486, Percent_Identity=37.2427983539095, Blast_Score=293, Evalue=2e-80,
Organism=Escherichia coli, GI1787823, Length=482, Percent_Identity=36.7219917012448, Blast_Score=281, Evalue=8e-77,
Organism=Escherichia coli, GI48994885, Length=402, Percent_Identity=26.3681592039801, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1790028, Length=210, Percent_Identity=26.6666666666667, Blast_Score=74, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6324401, Length=489, Percent_Identity=38.8548057259714, Blast_Score=357, Evalue=2e-99,
Organism=Saccharomyces cerevisiae, GI6320765, Length=489, Percent_Identity=38.8548057259714, Blast_Score=357, Evalue=2e-99,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR013328
- InterPro:   IPR000669
- InterPro:   IPR013118
- InterPro:   IPR013131
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01232 Mannitol_dh; PF08125 Mannitol_dh_C [H]

EC number: 1.1.1.67

Molecular weight: Translated: 51609; Mature: 51609

Theoretical pI: Translated: 4.96; Mature: 4.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLNAHNLTGLKIPVPTYDRSQIGIGIAHFGVGGFHRAHQAMYLDRLLNDGLARDWGICG
CCCCCCCCCEEEECCCCCCCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCEE
IGVLPDDRRMRDALRSQDYLYTLILEHPDGTQEPRVIGSIVDFRYAPEDPGSVVDLLADP
ECCCCCHHHHHHHHCCCCEEEEEEEECCCCCCCCHHHHHHHHCCCCCCCCCHHHHHHHCC
ATRIISLTITEGGYQPPLSAAFELVAEALNRRRERGLPSPTIVSCDNIIKNGDVARRAFT
CCEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEECHHHHHCCCHHHHHHHH
AHAEQVNPELAQWIRENTTFPNSMVDRITPTPTPDLVDRLAAEFGVQDAEPVVAEPFAMW
HHHHHCCHHHHHHHHHCCCCCHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCHHCCCEEE
VLEDDFADGRPPLDKAGVRLVDDVAPYEAIKLRLLNAGHQGLCYFAYLAGYREVHEAAQD
EEECCCCCCCCCHHHHCCCHHHHHCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCC
PVIAEFLARYMDSEAMPTLPRMPGLEDFRDGLIPRFANAYVGDQVARLCADSSDHIPKWL
CHHHHHHHHHHCCCCCCCCCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCHHHH
LPVVHDNLRSGGPVQLSAAIVASWARYAEGVDEQGRPIEVVDRLADTLVPLARSQRENPD
HHHHHHHHCCCCCEEHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCC
AFLANRAVFGDLIDAPRFREAYRWALDSLHRRGARATLRALIGADGS
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCC
>Mature Secondary Structure
MKLNAHNLTGLKIPVPTYDRSQIGIGIAHFGVGGFHRAHQAMYLDRLLNDGLARDWGICG
CCCCCCCCCEEEECCCCCCCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCEE
IGVLPDDRRMRDALRSQDYLYTLILEHPDGTQEPRVIGSIVDFRYAPEDPGSVVDLLADP
ECCCCCHHHHHHHHCCCCEEEEEEEECCCCCCCCHHHHHHHHCCCCCCCCCHHHHHHHCC
ATRIISLTITEGGYQPPLSAAFELVAEALNRRRERGLPSPTIVSCDNIIKNGDVARRAFT
CCEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEECHHHHHCCCHHHHHHHH
AHAEQVNPELAQWIRENTTFPNSMVDRITPTPTPDLVDRLAAEFGVQDAEPVVAEPFAMW
HHHHHCCHHHHHHHHHCCCCCHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCHHCCCEEE
VLEDDFADGRPPLDKAGVRLVDDVAPYEAIKLRLLNAGHQGLCYFAYLAGYREVHEAAQD
EEECCCCCCCCCHHHHCCCHHHHHCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCC
PVIAEFLARYMDSEAMPTLPRMPGLEDFRDGLIPRFANAYVGDQVARLCADSSDHIPKWL
CHHHHHHHHHHCCCCCCCCCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCHHHH
LPVVHDNLRSGGPVQLSAAIVASWARYAEGVDEQGRPIEVVDRLADTLVPLARSQRENPD
HHHHHHHHCCCCCEEHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCC
AFLANRAVFGDLIDAPRFREAYRWALDSLHRRGARATLRALIGADGS
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: D-mannitol; NAD+

Specific reaction: D-mannitol + NAD+ = D-fructose + NADH + H+

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA