The gene/protein map for NC_002944 is currently unavailable.
Definition Mycobacterium avium subsp. paratuberculosis K-10, complete genome.
Accession NC_002944
Length 4,829,781

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The map label for this gene is fabG [H]

Identifier: 41407573

GI number: 41407573

Start: 1614838

End: 1615737

Strand: Direct

Name: fabG [H]

Synonym: MAP1475

Alternate gene names: 41407573

Gene position: 1614838-1615737 (Clockwise)

Preceding gene: 41407569

Following gene: 41407576

Centisome position: 33.44

GC content: 72.22

Gene sequence:

>900_bases
GTGGCCGCGGTGAGCGGCGCCGATGCGTTACTGTCCGGGCGCGGCGCGGTGGTGTCGGGCGGCAGCCGCGGCATCGGGCG
CGCGGTCGCCGAACTGCTGGCCGGCCTGGGCGCCGGGGTGGTCGTCAACGGCCGCGACCCGCAGGCCGTGCAGGAGACGG
TTGCGGCGATCACCGCGGCCGGGGGGCGGGCCACCGCGGTGGTGGGCGCCGCCGACGACGAGCGCATCGCCCGAAGCCTC
GTCGACGAGTGCATCGGCGCGTTCGGGCGGCTGGACGCCTTGATCAACTGCGCCGGCATCGCCGAACCCGCGGGCTCGTC
GATCCTGAACATCACCGCCGACGAATTCGACCACCTCATCGGCGCCCACCTGGGCACCGCTTTCCACACCTGCCGGGCGG
CCGCCCCGGTCATGGTCGAGCAGCGGCACGGGTCCATCGTCAACACCAGCTCGGTGGCGTTCCTGGGCGACTACGGCGGG
ACCGGCTACCCGGCGGGCAAGGGTGCCGTCAACGCGCTGACCATGGCCATCGCCGCCGAACTGAAGGCCTACGGCGTCCG
GGCCAACGTGGTGTGTCCCGGCGCCCGGACACGGCTGTCCACCGGCGCCGACTACGAACGACACATCGAGGACCTGCACC
GTCGCGGGCTGCTCGACGACATGACCAGGCAGGCCTCGCTGGACAGCGCCCCGCCCGTCTTCGTGGCGCCGGTCTACGGT
TACCTCGTCAGCGACTTGGCGCGCGACGTGACGGGCCAAATCCTTGTCGCCGCAGGCGGTTTCGTGGGCAGCTTCGACCG
TCAAACACCGCGCCTGCTGGGCTACCGCGATCATCATCGGGCCGGGCCGTGGTCGATCGAGGAGGTGCACACGATGATCG
GCGCGGCGGCGACGCCATGA

Upstream 100 bases:

>100_bases
GGCTAATGTTCGACATCCCTGCCGGGCGGCTCGCCGGCATCCGATCGCGAAAACCGTTCGCGCGCAAGATTTTACCTCGC
CCGGATGCCGGCGCTGGGCG

Downstream 100 bases:

>100_bases
CCCGCCGGATCCGGACGTGCCGACGATTGCGGCCTACACCCGGTCGGTGGTGAAGTCGACCGCCTGATCGACCATCCCCG
CCTCGACGTACTGCCGATGC

Product: hypothetical protein

Products: NA

Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]

Number of amino acids: Translated: 299; Mature: 298

Protein sequence:

>299_residues
MAAVSGADALLSGRGAVVSGGSRGIGRAVAELLAGLGAGVVVNGRDPQAVQETVAAITAAGGRATAVVGAADDERIARSL
VDECIGAFGRLDALINCAGIAEPAGSSILNITADEFDHLIGAHLGTAFHTCRAAAPVMVEQRHGSIVNTSSVAFLGDYGG
TGYPAGKGAVNALTMAIAAELKAYGVRANVVCPGARTRLSTGADYERHIEDLHRRGLLDDMTRQASLDSAPPVFVAPVYG
YLVSDLARDVTGQILVAAGGFVGSFDRQTPRLLGYRDHHRAGPWSIEEVHTMIGAAATP

Sequences:

>Translated_299_residues
MAAVSGADALLSGRGAVVSGGSRGIGRAVAELLAGLGAGVVVNGRDPQAVQETVAAITAAGGRATAVVGAADDERIARSL
VDECIGAFGRLDALINCAGIAEPAGSSILNITADEFDHLIGAHLGTAFHTCRAAAPVMVEQRHGSIVNTSSVAFLGDYGG
TGYPAGKGAVNALTMAIAAELKAYGVRANVVCPGARTRLSTGADYERHIEDLHRRGLLDDMTRQASLDSAPPVFVAPVYG
YLVSDLARDVTGQILVAAGGFVGSFDRQTPRLLGYRDHHRAGPWSIEEVHTMIGAAATP
>Mature_298_residues
AAVSGADALLSGRGAVVSGGSRGIGRAVAELLAGLGAGVVVNGRDPQAVQETVAAITAAGGRATAVVGAADDERIARSLV
DECIGAFGRLDALINCAGIAEPAGSSILNITADEFDHLIGAHLGTAFHTCRAAAPVMVEQRHGSIVNTSSVAFLGDYGGT
GYPAGKGAVNALTMAIAAELKAYGVRANVVCPGARTRLSTGADYERHIEDLHRRGLLDDMTRQASLDSAPPVFVAPVYGY
LVSDLARDVTGQILVAAGGFVGSFDRQTPRLLGYRDHHRAGPWSIEEVHTMIGAAATP

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI4504505, Length=296, Percent_Identity=28.0405405405405, Blast_Score=90, Evalue=3e-18,
Organism=Homo sapiens, GI15277342, Length=259, Percent_Identity=32.4324324324324, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI40254992, Length=195, Percent_Identity=34.8717948717949, Blast_Score=83, Evalue=3e-16,
Organism=Homo sapiens, GI32483357, Length=262, Percent_Identity=29.0076335877863, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI4758504, Length=202, Percent_Identity=32.6732673267327, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI19923817, Length=267, Percent_Identity=25.4681647940075, Blast_Score=72, Evalue=9e-13,
Organism=Homo sapiens, GI4503817, Length=189, Percent_Identity=29.6296296296296, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI66933014, Length=191, Percent_Identity=29.3193717277487, Blast_Score=69, Evalue=6e-12,
Organism=Homo sapiens, GI5031737, Length=190, Percent_Identity=30.5263157894737, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI33667109, Length=190, Percent_Identity=30.5263157894737, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI83715985, Length=194, Percent_Identity=32.4742268041237, Blast_Score=66, Evalue=3e-11,
Organism=Homo sapiens, GI59889578, Length=118, Percent_Identity=35.5932203389831, Blast_Score=65, Evalue=7e-11,
Organism=Homo sapiens, GI20149619, Length=228, Percent_Identity=26.7543859649123, Blast_Score=65, Evalue=8e-11,
Organism=Escherichia coli, GI87082100, Length=254, Percent_Identity=28.740157480315, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1787335, Length=252, Percent_Identity=29.7619047619048, Blast_Score=92, Evalue=3e-20,
Organism=Escherichia coli, GI2367175, Length=192, Percent_Identity=38.0208333333333, Blast_Score=89, Evalue=2e-19,
Organism=Escherichia coli, GI87082160, Length=266, Percent_Identity=27.8195488721804, Blast_Score=85, Evalue=5e-18,
Organism=Escherichia coli, GI1786812, Length=258, Percent_Identity=31.0077519379845, Blast_Score=85, Evalue=7e-18,
Organism=Escherichia coli, GI1789378, Length=256, Percent_Identity=29.6875, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI1789208, Length=252, Percent_Identity=28.968253968254, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1788459, Length=271, Percent_Identity=27.3062730627306, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1790717, Length=254, Percent_Identity=25.1968503937008, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI1787905, Length=257, Percent_Identity=27.6264591439689, Blast_Score=64, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17568967, Length=264, Percent_Identity=29.9242424242424, Blast_Score=102, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI71994604, Length=259, Percent_Identity=30.5019305019305, Blast_Score=97, Evalue=9e-21,
Organism=Caenorhabditis elegans, GI25147288, Length=256, Percent_Identity=32.421875, Blast_Score=92, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17562908, Length=268, Percent_Identity=31.3432835820896, Blast_Score=92, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI71994600, Length=262, Percent_Identity=29.3893129770992, Blast_Score=92, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI17561402, Length=268, Percent_Identity=29.1044776119403, Blast_Score=91, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI17560332, Length=263, Percent_Identity=29.6577946768061, Blast_Score=90, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17562910, Length=196, Percent_Identity=32.6530612244898, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17560676, Length=267, Percent_Identity=27.3408239700375, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI193204405, Length=198, Percent_Identity=32.3232323232323, Blast_Score=85, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17531453, Length=267, Percent_Identity=30.7116104868914, Blast_Score=85, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI17562906, Length=199, Percent_Identity=33.6683417085427, Blast_Score=84, Evalue=7e-17,
Organism=Caenorhabditis elegans, GI17544670, Length=192, Percent_Identity=31.25, Blast_Score=84, Evalue=9e-17,
Organism=Caenorhabditis elegans, GI17555706, Length=269, Percent_Identity=28.996282527881, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17538486, Length=262, Percent_Identity=29.3893129770992, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17560220, Length=194, Percent_Identity=32.4742268041237, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17551412, Length=191, Percent_Identity=29.8429319371728, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17559104, Length=187, Percent_Identity=31.5508021390374, Blast_Score=79, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17564282, Length=190, Percent_Identity=30, Blast_Score=78, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17560150, Length=193, Percent_Identity=28.4974093264249, Blast_Score=78, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI17562904, Length=268, Percent_Identity=26.1194029850746, Blast_Score=77, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI17538480, Length=191, Percent_Identity=30.8900523560209, Blast_Score=77, Evalue=8e-15,
Organism=Caenorhabditis elegans, GI72000259, Length=212, Percent_Identity=29.7169811320755, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17538182, Length=199, Percent_Identity=32.1608040201005, Blast_Score=74, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI17563726, Length=193, Percent_Identity=27.979274611399, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17565030, Length=192, Percent_Identity=31.7708333333333, Blast_Score=71, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI71997099, Length=201, Percent_Identity=28.8557213930348, Blast_Score=71, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI17562990, Length=191, Percent_Identity=27.2251308900524, Blast_Score=68, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17508895, Length=190, Percent_Identity=27.3684210526316, Blast_Score=65, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6322861, Length=262, Percent_Identity=29.7709923664122, Blast_Score=98, Evalue=1e-21,
Organism=Saccharomyces cerevisiae, GI6324126, Length=269, Percent_Identity=26.3940520446097, Blast_Score=64, Evalue=2e-11,
Organism=Drosophila melanogaster, GI28571526, Length=257, Percent_Identity=33.852140077821, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI21357041, Length=257, Percent_Identity=33.0739299610895, Blast_Score=96, Evalue=3e-20,
Organism=Drosophila melanogaster, GI18859837, Length=257, Percent_Identity=31.5175097276265, Blast_Score=95, Evalue=6e-20,
Organism=Drosophila melanogaster, GI24644339, Length=262, Percent_Identity=29.7709923664122, Blast_Score=94, Evalue=7e-20,
Organism=Drosophila melanogaster, GI21355319, Length=259, Percent_Identity=28.957528957529, Blast_Score=90, Evalue=2e-18,
Organism=Drosophila melanogaster, GI23397609, Length=261, Percent_Identity=29.5019157088123, Blast_Score=87, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24639444, Length=263, Percent_Identity=29.277566539924, Blast_Score=82, Evalue=5e-16,
Organism=Drosophila melanogaster, GI17737361, Length=190, Percent_Identity=31.0526315789474, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24643142, Length=195, Percent_Identity=29.7435897435897, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI21357673, Length=203, Percent_Identity=28.0788177339901, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI21356301, Length=190, Percent_Identity=30.5263157894737, Blast_Score=65, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011284
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.100 [H]

Molecular weight: Translated: 30565; Mature: 30434

Theoretical pI: Translated: 6.23; Mature: 6.23

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure: 

>Translated Secondary Structure
MAAVSGADALLSGRGAVVSGGSRGIGRAVAELLAGLGAGVVVNGRDPQAVQETVAAITAA
CCCCCCCHHHHCCCCCEEECCCCCHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHHCC
GGRATAVVGAADDERIARSLVDECIGAFGRLDALINCAGIAEPAGSSILNITADEFDHLI
CCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEHHHHHHHH
GAHLGTAFHTCRAAAPVMVEQRHGSIVNTSSVAFLGDYGGTGYPAGKGAVNALTMAIAAE
HHHHHHHHHHHHHCCCCEEECCCCCEEECCCEEEEECCCCCCCCCCCHHHHHHHHHHHHH
LKAYGVRANVVCPGARTRLSTGADYERHIEDLHRRGLLDDMTRQASLDSAPPVFVAPVYG
HHHHCCEEEEECCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHCCCCCCCEEEHHHHH
YLVSDLARDVTGQILVAAGGFVGSFDRQTPRLLGYRDHHRAGPWSIEEVHTMIGAAATP
HHHHHHHHHHCCEEEEEECCCCCCCCCCCCHHCCCCCCCCCCCCCHHHHHHHHHHCCCC
>Mature Secondary Structure 
AAVSGADALLSGRGAVVSGGSRGIGRAVAELLAGLGAGVVVNGRDPQAVQETVAAITAA
CCCCCCHHHHCCCCCEEECCCCCHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHHCC
GGRATAVVGAADDERIARSLVDECIGAFGRLDALINCAGIAEPAGSSILNITADEFDHLI
CCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEHHHHHHHH
GAHLGTAFHTCRAAAPVMVEQRHGSIVNTSSVAFLGDYGGTGYPAGKGAVNALTMAIAAE
HHHHHHHHHHHHHCCCCEEECCCCCEEECCCEEEEECCCCCCCCCCCHHHHHHHHHHHHH
LKAYGVRANVVCPGARTRLSTGADYERHIEDLHRRGLLDDMTRQASLDSAPPVFVAPVYG
HHHHCCEEEEECCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHCCCCCCCEEEHHHHH
YLVSDLARDVTGQILVAAGGFVGSFDRQTPRLLGYRDHHRAGPWSIEEVHTMIGAAATP
HHHHHHHHHHCCEEEEEECCCCCCCCCCCCHHCCCCCCCCCCCCCHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8759840; 9384377; 9534248; 8654983 [H]