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The map label for this gene is yciL [C]

Identifier: 41407511

GI number: 41407511

Start: 1525811

End: 1526554

Strand: Direct

Name: yciL [C]

Synonym: MAP1413

Alternate gene names: 41407511

Gene position: 1525811-1526554 (Clockwise)

Preceding gene: 41407510

Following gene: 41407512

Centisome position: 31.59

GC content: 69.09

Gene sequence:

>744_bases
ATGGTCGAAGCTCAGGGCATCCGGCTGCAAAAGGTGTTGTCGCAGGCCGGAATCGCGTCGCGGCGGGCCGCCGAGAAGTT
GATCGTCGACGGCCGCGTCGAGGTGGACGGGCAGGTGGTGACCGAGCTGGGCACCCGCGTCGACCCGGATGCCGCGGTGA
TCCGGGTCGACGGGGCCCGGGTGGTCCTCGATGAGTCGCAGGTCTATCTGGCGCTGAACAAGCCGCGCGGGGTGCACTCG
ACGATGTCGGACGACCGCGGCCGGCCGTGCATCGGCGACCTGATCGAACGTCGAGTTCGCGGCAACAAGAACCTGTTTCA
CGTCGGGCGGTTGGACGCCGAGACCGAAGGGCTGATCCTGCTGACCAACGACGGCGAACTCGCGCACCGGTTGATGCATC
CCTCCCACGAGGTGCCCAAGACGTATCTGGCGACGGTCACCGGATCGATACCGCGCGGGCTGGGCAAGACGCTGCGCGCG
GGCATCGAGCTGGACGACGGGATGGCGCGCGTCGACGAGTTCGCGGTGGTGGACCCCATCCCGGGCAAGACGCTGGTGCG
GGTGACGTTGCACGAGGGGCGGAATCGCATTGTGCGCCGGCTGCTGGCCGCCGCGGGCTTCCCGGTCGAGTCGTTGGTGC
GCACCGACATCGGGCCGATTTCCCTGGGCAAGCAGCGGCCGGGCAGCATTCGTGCGCTGGGACGCGACGAGGTGGGCCGG
CTCTACCAGGCGGTCGGGCTGTGA

Upstream 100 bases:

>100_bases
AGGACTTGAGCGAATCCCTGGACAGCGAGCCACGTTTCGTCAAACTCTCCGGCGGTCAGGCCTCCGATGCGGCGCTGACG
TTCGACGTGGACCAGGATTG

Downstream 100 bases:

>100_bases
GCTCCGACGTCGTGGTGGCCATCGATGGCCCCGCTGGGACCGGAAAGTCCTCCGTCTCAAAGGGATTGGCGCGCGCGCTG
GGTGCGCGCTATCTGGACAC

Product: hypothetical protein

Products: NA

Alternate protein names: RNA pseudouridylate synthase; RNA-uridine isomerase [H]

Number of amino acids: Translated: 247; Mature: 247

Protein sequence:

>247_residues
MVEAQGIRLQKVLSQAGIASRRAAEKLIVDGRVEVDGQVVTELGTRVDPDAAVIRVDGARVVLDESQVYLALNKPRGVHS
TMSDDRGRPCIGDLIERRVRGNKNLFHVGRLDAETEGLILLTNDGELAHRLMHPSHEVPKTYLATVTGSIPRGLGKTLRA
GIELDDGMARVDEFAVVDPIPGKTLVRVTLHEGRNRIVRRLLAAAGFPVESLVRTDIGPISLGKQRPGSIRALGRDEVGR
LYQAVGL

Sequences:

>Translated_247_residues
MVEAQGIRLQKVLSQAGIASRRAAEKLIVDGRVEVDGQVVTELGTRVDPDAAVIRVDGARVVLDESQVYLALNKPRGVHS
TMSDDRGRPCIGDLIERRVRGNKNLFHVGRLDAETEGLILLTNDGELAHRLMHPSHEVPKTYLATVTGSIPRGLGKTLRA
GIELDDGMARVDEFAVVDPIPGKTLVRVTLHEGRNRIVRRLLAAAGFPVESLVRTDIGPISLGKQRPGSIRALGRDEVGR
LYQAVGL
>Mature_247_residues
MVEAQGIRLQKVLSQAGIASRRAAEKLIVDGRVEVDGQVVTELGTRVDPDAAVIRVDGARVVLDESQVYLALNKPRGVHS
TMSDDRGRPCIGDLIERRVRGNKNLFHVGRLDAETEGLILLTNDGELAHRLMHPSHEVPKTYLATVTGSIPRGLGKTLRA
GIELDDGMARVDEFAVVDPIPGKTLVRVTLHEGRNRIVRRLLAAAGFPVESLVRTDIGPISLGKQRPGSIRALGRDEVGR
LYQAVGL

Specific function: Unknown

COG id: COG1187

COG function: function code J; 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 S4 RNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787524, Length=225, Percent_Identity=42.6666666666667, Blast_Score=135, Evalue=3e-33,
Organism=Escherichia coli, GI1790453, Length=247, Percent_Identity=32.7935222672065, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI1788510, Length=236, Percent_Identity=32.6271186440678, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI87081838, Length=176, Percent_Identity=35.7954545454545, Blast_Score=89, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020103
- InterPro:   IPR006145
- InterPro:   IPR000748
- InterPro:   IPR018496
- InterPro:   IPR002942 [H]

Pfam domain/function: PF00849 PseudoU_synth_2; PF01479 S4 [H]

EC number: NA

Molecular weight: Translated: 26802; Mature: 26802

Theoretical pI: Translated: 9.89; Mature: 9.89

Prosite motif: PS50889 S4 ; PS01149 PSI_RSU

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVEAQGIRLQKVLSQAGIASRRAAEKLIVDGRVEVDGQVVTELGTRVDPDAAVIRVDGAR
CCCCCCCHHHHHHHHHCHHHHHHHHHHEECCEEEECCHHHHHHCCCCCCCCEEEEECCEE
VVLDESQVYLALNKPRGVHSTMSDDRGRPCIGDLIERRVRGNKNLFHVGRLDAETEGLIL
EEEECCEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCEEEEECCCCCCCCEEE
LTNDGELAHRLMHPSHEVPKTYLATVTGSIPRGLGKTLRAGIELDDGMARVDEFAVVDPI
EECCHHHHHHHHCCCCCCCHHHHHHHCCCCCHHHHHHHHCCCCCCCCHHHHHHEEEECCC
PGKTLVRVTLHEGRNRIVRRLLAAAGFPVESLVRTDIGPISLGKQRPGSIRALGRDEVGR
CCCEEEEEEEHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCCCCCCCCEEECCHHHHHH
LYQAVGL
HHHHHCC
>Mature Secondary Structure
MVEAQGIRLQKVLSQAGIASRRAAEKLIVDGRVEVDGQVVTELGTRVDPDAAVIRVDGAR
CCCCCCCHHHHHHHHHCHHHHHHHHHHEECCEEEECCHHHHHHCCCCCCCCEEEEECCEE
VVLDESQVYLALNKPRGVHSTMSDDRGRPCIGDLIERRVRGNKNLFHVGRLDAETEGLIL
EEEECCEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCEEEEECCCCCCCCEEE
LTNDGELAHRLMHPSHEVPKTYLATVTGSIPRGLGKTLRAGIELDDGMARVDEFAVVDPI
EECCHHHHHHHHCCCCCCCHHHHHHHCCCCCHHHHHHHHCCCCCCCCHHHHHHEEEECCC
PGKTLVRVTLHEGRNRIVRRLLAAAGFPVESLVRTDIGPISLGKQRPGSIRALGRDEVGR
CCCEEEEEEEHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCCCCCCCCEEECCHHHHHH
LYQAVGL
HHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]