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The map label for this gene is xerD

Identifier: 41407506

GI number: 41407506

Start: 1521473

End: 1522414

Strand: Direct

Name: xerD

Synonym: MAP1408

Alternate gene names: 41407506

Gene position: 1521473-1522414 (Clockwise)

Preceding gene: 41407505

Following gene: 41407508

Centisome position: 31.5

GC content: 73.99

Gene sequence:

>942_bases
ATGACGACGGTGGCGTTGGAGACCCAACTGCAGGGCTACCTCGACCACCTCACGATCGAGCGGGGCGTCGCGGCGAACAC
GCTCAGCTCGTATCGGCGCGACCTGCGCCGCTACACCAAACACCTGTCGGACCGCGGGATTTCGGACCTGGCCAAGGTGG
GCGAGGACGACGTGAGCGAGTTCCTGGTGGCGCTGCGCCGCGGCGATCCCGACACCGGCGCCGCCGCGCTGTCGGCGGTG
TCGGCGGCCCGCGCCCTGATCGCGGTGCGCGGCTTGCACCGGTTCCTGGCGGCCGAGGGGTTGGCCGAACTCGACGTCGC
CCGCGCCGTGCGCCCGCCGACGCCGGGCCGCCGGCTGCCCAAGAGCCTGACCATCGACCAGGTGCTGGCGCTGCTGGAGG
CGGCGGGCGGCGAGAGCCCCGCCGACGGCCCGCTGACCCTGCGGAACCGGGCGTTGCTGGAACTGCTGTACTCCACCGGC
GCGCGCATCTCCGAGGCCGTCGGCCTCGACGTCGACGACGTCGACACCCAGGCCCGGTCGGTGCTGCTGCGCGGCAAGGG
CGGCAAGCAGCGGTTGGTGCCCATCGGGCGTCCCGCCGTGGCCGCGCTGGATGCCTATCTGGTGCGCGGCCGCTGGGAGC
TGGCGCGCCGCGGGCGCGGCACGCCAGCCATCTTCCTCAACGTGCGCGGCGGCCGGCTGTCGCGGCAAAGCGCCTGGCAG
GTGCTGCAGGACGCGGCCGAGCGCGCCGGGATCACCTCGGGGGTGTCGCCGCACATGCTGCGGCATTCGTTCGCCACCCA
CCTGCTCGAGGGCGGCGCCGACGTGCGGGTGGTGCAGGAGTTGCTCGGCCACGCCTCGGTCACGACGACGCAGATCTACA
CCATGGTCACCGTGCACGCGCTGCGCGAGGTGTGGGCCGAGGCGCACCCGCGGGCGCGCTGA

Upstream 100 bases:

>100_bases
TGGCCGCCCACGCCGTCACGACGGGATTTGAGCGACCGCGTCCGGTGGACAGCCCGTGGCAGGACCGGCCCACGGCGTTT
CCCGCGCGGAAGGCCGGGCG

Downstream 100 bases:

>100_bases
CCATCTCGCCGCCGCGCGCCGCCTCTCAGCCCAGGTATTCGGACTCCAGCATCAGGTCGGAGAGCATGGTCTGGTACTCG
GCATGCGTCTTGTGCTCGAC

Product: site-specific tyrosine recombinase XerD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 313; Mature: 312

Protein sequence:

>313_residues
MTTVALETQLQGYLDHLTIERGVAANTLSSYRRDLRRYTKHLSDRGISDLAKVGEDDVSEFLVALRRGDPDTGAAALSAV
SAARALIAVRGLHRFLAAEGLAELDVARAVRPPTPGRRLPKSLTIDQVLALLEAAGGESPADGPLTLRNRALLELLYSTG
ARISEAVGLDVDDVDTQARSVLLRGKGGKQRLVPIGRPAVAALDAYLVRGRWELARRGRGTPAIFLNVRGGRLSRQSAWQ
VLQDAAERAGITSGVSPHMLRHSFATHLLEGGADVRVVQELLGHASVTTTQIYTMVTVHALREVWAEAHPRAR

Sequences:

>Translated_313_residues
MTTVALETQLQGYLDHLTIERGVAANTLSSYRRDLRRYTKHLSDRGISDLAKVGEDDVSEFLVALRRGDPDTGAAALSAV
SAARALIAVRGLHRFLAAEGLAELDVARAVRPPTPGRRLPKSLTIDQVLALLEAAGGESPADGPLTLRNRALLELLYSTG
ARISEAVGLDVDDVDTQARSVLLRGKGGKQRLVPIGRPAVAALDAYLVRGRWELARRGRGTPAIFLNVRGGRLSRQSAWQ
VLQDAAERAGITSGVSPHMLRHSFATHLLEGGADVRVVQELLGHASVTTTQIYTMVTVHALREVWAEAHPRAR
>Mature_312_residues
TTVALETQLQGYLDHLTIERGVAANTLSSYRRDLRRYTKHLSDRGISDLAKVGEDDVSEFLVALRRGDPDTGAAALSAVS
AARALIAVRGLHRFLAAEGLAELDVARAVRPPTPGRRLPKSLTIDQVLALLEAAGGESPADGPLTLRNRALLELLYSTGA
RISEAVGLDVDDVDTQARSVLLRGKGGKQRLVPIGRPAVAALDAYLVRGRWELARRGRGTPAIFLNVRGGRLSRQSAWQV
LQDAAERAGITSGVSPHMLRHSFATHLLEGGADVRVVQELLGHASVTTTQIYTMVTVHALREVWAEAHPRAR

Specific function: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The xerC-xerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell div

COG id: COG4974

COG function: function code L; Site-specific recombinase XerD

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family. XerD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789261, Length=305, Percent_Identity=42.9508196721311, Blast_Score=209, Evalue=2e-55,
Organism=Escherichia coli, GI1790244, Length=309, Percent_Identity=36.5695792880259, Blast_Score=184, Evalue=9e-48,
Organism=Escherichia coli, GI1790768, Length=176, Percent_Identity=35.7954545454545, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1790767, Length=193, Percent_Identity=31.6062176165803, Blast_Score=90, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR010998
- InterPro:   IPR023109
- InterPro:   IPR004107
- InterPro:   IPR011932 [H]

Pfam domain/function: PF02899 Phage_integr_N; PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 33767; Mature: 33636

Theoretical pI: Translated: 10.45; Mature: 10.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
0.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTVALETQLQGYLDHLTIERGVAANTLSSYRRDLRRYTKHLSDRGISDLAKVGEDDVSE
CCEEEHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCHHHHHH
FLVALRRGDPDTGAAALSAVSAARALIAVRGLHRFLAAEGLAELDVARAVRPPTPGRRLP
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCC
KSLTIDQVLALLEAAGGESPADGPLTLRNRALLELLYSTGARISEAVGLDVDDVDTQARS
CCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHCCCCHHHHHHHHH
VLLRGKGGKQRLVPIGRPAVAALDAYLVRGRWELARRGRGTPAIFLNVRGGRLSRQSAWQ
EEHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHH
VLQDAAERAGITSGVSPHMLRHSFATHLLEGGADVRVVQELLGHASVTTTQIYTMVTVHA
HHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCHHHHHHHHHHHHHH
LREVWAEAHPRAR
HHHHHHHCCCCCC
>Mature Secondary Structure 
TTVALETQLQGYLDHLTIERGVAANTLSSYRRDLRRYTKHLSDRGISDLAKVGEDDVSE
CEEEHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCHHHHHH
FLVALRRGDPDTGAAALSAVSAARALIAVRGLHRFLAAEGLAELDVARAVRPPTPGRRLP
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCC
KSLTIDQVLALLEAAGGESPADGPLTLRNRALLELLYSTGARISEAVGLDVDDVDTQARS
CCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHCCCCHHHHHHHHH
VLLRGKGGKQRLVPIGRPAVAALDAYLVRGRWELARRGRGTPAIFLNVRGGRLSRQSAWQ
EEHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHH
VLQDAAERAGITSGVSPHMLRHSFATHLLEGGADVRVVQELLGHASVTTTQIYTMVTVHA
HHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCHHHHHHHHHHHHHH
LREVWAEAHPRAR
HHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]