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The map label for this gene is merR [H]

Identifier: 41407357

GI number: 41407357

Start: 1340437

End: 1340913

Strand: Direct

Name: merR [H]

Synonym: MAP1259

Alternate gene names: 41407357

Gene position: 1340437-1340913 (Clockwise)

Preceding gene: 41407355

Following gene: 41407358

Centisome position: 27.75

GC content: 71.7

Gene sequence:

>477_bases
ATGGCCCCAGTCAACGACTTAGAGTTAACTCTGAGTCAAGCACGAACCCGGGAGCCGCCCATGCTGACCATCGGCGAGGT
CGCGCGCCGCAGCGGGGTCGCCGCGACCACCCTGCGCTACTACGAGCAGATCGGCCTGCTGCCCGCCCCGATCCGGCTGG
GCGGGCAGCGCCGCTACGACGAGGCCGTGCTGTCCCGGCTCGAGGTGATCGCGCTGTGCAAGACCGCCGGCTTCGCGCTG
GACGAGATCCAGCGCCTGTTCGCCGACGACGCGCCGGGACGCCCGGCCAGCCGCGCGCTGGCCCGGGCCAAACTCGCCCA
GATCGACGCCCAGCTGGAGTCGCTGGCCCGGGCCCGCGCCGTCATCGAGTGGGGGATGCGGTGCACTTGCCCGTCGATCG
ACGCCTGCACCTGCGGCATTCACCCAACCCGGCCCGCACCCGTCGGCCCGGACGTCCGCTCAGCCAGAAGGTTCTGA

Upstream 100 bases:

>100_bases
GGCGAACCAGATCGGGGTGTCGACGGGAGTGCCGTCGCGGCGGAAAGACCGCAGCAGCGCATAGCGGTCGGTGTGCAACT
CGGCGAAGGATCGATGCGGC

Downstream 100 bases:

>100_bases
TCCGGGGCAAGGAGAGCGGAAATGACGGCGGAACGTCCGGCCACCTTGTGCGAGGCATTCCAGCGCAACGCCGCGATCGA
CCCGGACGCGGTCGTGCTGC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 158; Mature: 157

Protein sequence:

>158_residues
MAPVNDLELTLSQARTREPPMLTIGEVARRSGVAATTLRYYEQIGLLPAPIRLGGQRRYDEAVLSRLEVIALCKTAGFAL
DEIQRLFADDAPGRPASRALARAKLAQIDAQLESLARARAVIEWGMRCTCPSIDACTCGIHPTRPAPVGPDVRSARRF

Sequences:

>Translated_158_residues
MAPVNDLELTLSQARTREPPMLTIGEVARRSGVAATTLRYYEQIGLLPAPIRLGGQRRYDEAVLSRLEVIALCKTAGFAL
DEIQRLFADDAPGRPASRALARAKLAQIDAQLESLARARAVIEWGMRCTCPSIDACTCGIHPTRPAPVGPDVRSARRF
>Mature_157_residues
APVNDLELTLSQARTREPPMLTIGEVARRSGVAATTLRYYEQIGLLPAPIRLGGQRRYDEAVLSRLEVIALCKTAGFALD
EIQRLFADDAPGRPASRALARAKLAQIDAQLESLARARAVIEWGMRCTCPSIDACTCGIHPTRPAPVGPDVRSARRF

Specific function: Mediates the mercuric-dependent induction of mercury resistance operon. In the absence of mercury merR represses transcription by binding tightly to the mer operator region; when mercury is present the dimeric complex binds a single ion and becomes a pote

COG id: COG0789

COG function: function code K; Predicted transcriptional regulators

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH merR-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009061
- InterPro:   IPR000551
- InterPro:   IPR011794
- InterPro:   IPR015358 [H]

Pfam domain/function: PF00376 MerR; PF09278 MerR-DNA-bind [H]

EC number: NA

Molecular weight: Translated: 17224; Mature: 17093

Theoretical pI: Translated: 9.08; Mature: 9.08

Prosite motif: PS00552 HTH_MERR_1 ; PS50937 HTH_MERR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.2 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
3.2 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAPVNDLELTLSQARTREPPMLTIGEVARRSGVAATTLRYYEQIGLLPAPIRLGGQRRYD
CCCCCHHHHHHHHHHCCCCCEEHHHHHHHHCCCHHHHHHHHHHHCCCCCCHHCCCCCHHH
EAVLSRLEVIALCKTAGFALDEIQRLFADDAPGRPASRALARAKLAQIDAQLESLARARA
HHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
VIEWGMRCTCPSIDACTCGIHPTRPAPVGPDVRSARRF
HHHHCCCCCCCCCCCEECCCCCCCCCCCCCCCHHHCCC
>Mature Secondary Structure 
APVNDLELTLSQARTREPPMLTIGEVARRSGVAATTLRYYEQIGLLPAPIRLGGQRRYD
CCCCHHHHHHHHHHCCCCCEEHHHHHHHHCCCHHHHHHHHHHHCCCCCCHHCCCCCHHH
EAVLSRLEVIALCKTAGFALDEIQRLFADDAPGRPASRALARAKLAQIDAQLESLARARA
HHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
VIEWGMRCTCPSIDACTCGIHPTRPAPVGPDVRSARRF
HHHHCCCCCCCCCCCEECCCCCCCCCCCCCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2666393 [H]