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The map label for this gene is ruvB

Identifier: 41407136

GI number: 41407136

Start: 1082498

End: 1083553

Strand: Direct

Name: ruvB

Synonym: MAP1038

Alternate gene names: 41407136

Gene position: 1082498-1083553 (Clockwise)

Preceding gene: 41407135

Following gene: 41407137

Centisome position: 22.41

GC content: 73.39

Gene sequence:

>1056_bases
ATGACCGCCCATGACGCCGACTGGTCGGATCGCGACGTCTCGGGCGCCCTGGTACCCGGCGAAGGCGACATCGACGTCAG
CCTGCGACCCCGCTCGCTGCGCGAATTCATCGGCCAGCCGCGGGTGCGCGAACAGCTGCAGCTGGTCATCGAGGGCGCCA
AGAACCGCGGCGGCACCCCCGATCACATCCTTCTGTCCGGCCCGCCGGGGCTGGGCAAGACGTCGCTGGCCATGATCATC
GCCGCCGAGCTGGGATCGTCGCTACGGGTGACGTCCGGCCCGGCGCTGGAACGCGCCGGCGACCTGGCGGCCATGCTGTC
CAACCTGGTCGAGCACGACGTGCTGTTCATCGACGAGATCCACCGCATCGCCCGGCCGGCCGAGGAGATGCTCTACCTGG
CGATGGAGGACTTCCGCGTCGACGTGGTGGTCGGCAAGGGCCCGGGGGCGACGTCGATCCCGCTGGAGGTGGCGCCGTTC
ACCCTGGTCGGCGCCACCACCCGGTCCGGCGCGCTGACCGGCCCGCTGCGGGACCGGTTCGGCTTCACCGCGCACATGGA
CTTCTACGAGCCGGCCGAGCTGCAGCAGGTGCTGGCCCGCTCGGCCGGCATCCTGGGCATCGAGCTGGGCGCCGAGGCGG
CCGAGGAGATCGCCCGGCGCTCGCGCGGCACACCGCGGATCGCCAACCGGCTGCTGCGCCGGGTCCGCGACTTCGCCGAG
GTGCGCGCCGACGGGGTGATCACCCGTGACGTCGCCAAGGCCGCGCTGGCCGTCTACGACGTCGACGAACTCGGCCTGGA
CCGGCTGGACCGCGCCGTGCTCACCGCGCTGACTCGCAGCTTCGGCGGCGGCCCGGTCGGGGTGTCGACGCTGGCGGTGG
CGGTGGGCGAGGAGGCCGCCACGGTCGAGGAGGTGTGCGAACCGTTCCTGGTCCGCGCCGGCATGGTGGCCCGCACGCCG
CGCGGCCGGGTGGCCACCGCCCAGGCCTGGACACACTTGGGCATGGTCCCCCCGGCCGGGGCCGCCGGGCTGGGTCAACC
CGGTCTGTTCGACTGA

Upstream 100 bases:

>100_bases
GGCACCTCCGGCGCGCTGCGCGCCGCCCTGTCGCTGCTGGGGAAGTCCCGATGACCGCCGACGACGATGCAGAGCGAAGC
GATGAGGAGGAGCGGCGCAG

Downstream 100 bases:

>100_bases
CCGGCTCGACCACCCGGCGGTGTTACTGCCCCTCCACATCTTTGTGATGGAATCGTTGGCCTGGACCTCGCCGCGCGCCC
GGGCCGCCGTCGGCGCCACC

Product: Holliday junction DNA helicase RuvB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 351; Mature: 350

Protein sequence:

>351_residues
MTAHDADWSDRDVSGALVPGEGDIDVSLRPRSLREFIGQPRVREQLQLVIEGAKNRGGTPDHILLSGPPGLGKTSLAMII
AAELGSSLRVTSGPALERAGDLAAMLSNLVEHDVLFIDEIHRIARPAEEMLYLAMEDFRVDVVVGKGPGATSIPLEVAPF
TLVGATTRSGALTGPLRDRFGFTAHMDFYEPAELQQVLARSAGILGIELGAEAAEEIARRSRGTPRIANRLLRRVRDFAE
VRADGVITRDVAKAALAVYDVDELGLDRLDRAVLTALTRSFGGGPVGVSTLAVAVGEEAATVEEVCEPFLVRAGMVARTP
RGRVATAQAWTHLGMVPPAGAAGLGQPGLFD

Sequences:

>Translated_351_residues
MTAHDADWSDRDVSGALVPGEGDIDVSLRPRSLREFIGQPRVREQLQLVIEGAKNRGGTPDHILLSGPPGLGKTSLAMII
AAELGSSLRVTSGPALERAGDLAAMLSNLVEHDVLFIDEIHRIARPAEEMLYLAMEDFRVDVVVGKGPGATSIPLEVAPF
TLVGATTRSGALTGPLRDRFGFTAHMDFYEPAELQQVLARSAGILGIELGAEAAEEIARRSRGTPRIANRLLRRVRDFAE
VRADGVITRDVAKAALAVYDVDELGLDRLDRAVLTALTRSFGGGPVGVSTLAVAVGEEAATVEEVCEPFLVRAGMVARTP
RGRVATAQAWTHLGMVPPAGAAGLGQPGLFD
>Mature_350_residues
TAHDADWSDRDVSGALVPGEGDIDVSLRPRSLREFIGQPRVREQLQLVIEGAKNRGGTPDHILLSGPPGLGKTSLAMIIA
AELGSSLRVTSGPALERAGDLAAMLSNLVEHDVLFIDEIHRIARPAEEMLYLAMEDFRVDVVVGKGPGATSIPLEVAPFT
LVGATTRSGALTGPLRDRFGFTAHMDFYEPAELQQVLARSAGILGIELGAEAAEEIARRSRGTPRIANRLLRRVRDFAEV
RADGVITRDVAKAALAVYDVDELGLDRLDRAVLTALTRSFGGGPVGVSTLAVAVGEEAATVEEVCEPFLVRAGMVARTPR
GRVATAQAWTHLGMVPPAGAAGLGQPGLFD

Specific function: The ruvA-ruvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is an helicase that mediates the Holliday

COG id: COG2255

COG function: function code L; Holliday junction resolvasome, helicase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvB family [H]

Homologues:

Organism=Escherichia coli, GI1788167, Length=330, Percent_Identity=55.1515151515151, Blast_Score=385, Evalue=1e-108,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR003959
- InterPro:   IPR004605
- InterPro:   IPR008823
- InterPro:   IPR011991
- ProDom:   PD005323 [H]

Pfam domain/function: PF00004 AAA; PF05491 RuvB_C [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 37189; Mature: 37058

Theoretical pI: Translated: 5.03; Mature: 5.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAHDADWSDRDVSGALVPGEGDIDVSLRPRSLREFIGQPRVREQLQLVIEGAKNRGGTP
CCCCCCCCCCCCCCCEEECCCCCEEEEECHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCC
DHILLSGPPGLGKTSLAMIIAAELGSSLRVTSGPALERAGDLAAMLSNLVEHDVLFIDEI
CEEEEECCCCCCHHHHHHHHHHHCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
HRIARPAEEMLYLAMEDFRVDVVVGKGPGATSIPLEVAPFTLVGATTRSGALTGPLRDRF
HHHHCCHHHHHHHHHHCCEEEEEEECCCCCCCCCEEECCEEEEECCCCCCCCCCCHHHHC
GFTAHMDFYEPAELQQVLARSAGILGIELGAEAAEEIARRSRGTPRIANRLLRRVRDFAE
CCEEECCCCCHHHHHHHHHHHCCEEEEECCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
VRADGVITRDVAKAALAVYDVDELGLDRLDRAVLTALTRSFGGGPVGVSTLAVAVGEEAA
HHHCCCHHHHHHHHHHHHHCHHHHCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCHHH
TVEEVCEPFLVRAGMVARTPRGRVATAQAWTHLGMVPPAGAAGLGQPGLFD
HHHHHHHHHHHHCCHHHCCCCCCEEHHHHHHHCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TAHDADWSDRDVSGALVPGEGDIDVSLRPRSLREFIGQPRVREQLQLVIEGAKNRGGTP
CCCCCCCCCCCCCCEEECCCCCEEEEECHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCC
DHILLSGPPGLGKTSLAMIIAAELGSSLRVTSGPALERAGDLAAMLSNLVEHDVLFIDEI
CEEEEECCCCCCHHHHHHHHHHHCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
HRIARPAEEMLYLAMEDFRVDVVVGKGPGATSIPLEVAPFTLVGATTRSGALTGPLRDRF
HHHHCCHHHHHHHHHHCCEEEEEEECCCCCCCCCEEECCEEEEECCCCCCCCCCCHHHHC
GFTAHMDFYEPAELQQVLARSAGILGIELGAEAAEEIARRSRGTPRIANRLLRRVRDFAE
CCEEECCCCCHHHHHHHHHHHCCEEEEECCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
VRADGVITRDVAKAALAVYDVDELGLDRLDRAVLTALTRSFGGGPVGVSTLAVAVGEEAA
HHHCCCHHHHHHHHHHHHHCHHHHCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCHHH
TVEEVCEPFLVRAGMVARTPRGRVATAQAWTHLGMVPPAGAAGLGQPGLFD
HHHHHHHHHHHHCCHHHCCCCCCEEHHHHHHHCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA