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The map label for this gene is aroB [H]

Identifier: 41407091

GI number: 41407091

Start: 1033680

End: 1034630

Strand: Direct

Name: aroB [H]

Synonym: MAP0993

Alternate gene names: 41407091

Gene position: 1033680-1034630 (Clockwise)

Preceding gene: 41407090

Following gene: 41407092

Centisome position: 21.4

GC content: 71.5

Gene sequence:

>951_bases
ATGGTGACCGGCAGGCTCGCGGGAATCGACTGCGGCACCAACTCGATCCGGTTGCTGATCGCCGACGTGCGCGACGGCCG
GCTGCGCGACGTGCACCGGGAGACCCGGATCGTGCGGTTGGGTCAGGGTGTGGACGCGACCGGGGAGTTCGCGCCGGAGG
CCATCGCGCGCACCCGCGCGGCGCTGAGCGACTACGCGGATCTGCTGAAACAACATGGTGTGCAGCGGGTGCGGATGGTG
GCCACGTCGGCCGCCCGGGACGTCGGCAACCGGGCCGACTTCTTTTCCATGACGGCCGACGTGCTGGGCGCGGTGCTGCC
CGGTGCGGTGGCCGAAGTGATCACCGGCGCCGACGAGGCCGAGCTGTCGTTCCGCGGGGCGGTCGGCGAATTGGACAGTG
CGGCCGGTCCTTTCGTGGTCGTCGACCTGGGCGGCGGGTCGACGGAGATCGTGGTCGGCGGCAGTGACGGGGTGACGGCG
AGCCACTCGGCCGACATCGGCTGCGTGCGGCTGACCGAGCGATGCCTGCATTCCGACCCGCCGACGCCCGAGGAGGTGGC
GCTGGCCCGTCAGGTGGTGCGCGAACGGCTCGAGGTCGCGCTGGGGGTGGTGCCCGTGGAAGGGGCGCGAACCTGGGTCG
GGGTGGCCGGGACGATGACCACGCTGTCGGCGCTGGCTCACGATTTGCCCGCGTATGATTCTGCGGCCATTCATCTTTCG
CGGGTGAGCGGGCGGGATCTGCTGGCGGTGTGCGAACGGCTGATCGGCATGACGCGGGCCCAGCGCGCGGCGCTGCCGCC
GATGCACGCGGGTCGGGCCGACGTGATCGCCGGAGGCGCGGTCGTGGTGGAGGAACTGGCGCGGGAGTTGCGTGCCCGCG
CGGGCATCGACGAGCTGACGGTCAGCGAGCACGACATCCTGGACGGCATCGTGCTGTCCATCGCGGGGTAG

Upstream 100 bases:

>100_bases
ATTCGCTGGCCAAGGGGCCGGGCGTGAATCCCTTTGGGGACCAGGCGTTGTCGATCCTGGCCGCCGATCCCGCGCTGGCC
GGAGTTTTACAGGAGGGCCG

Downstream 100 bases:

>100_bases
GCCACTTCGGTCACGGACGTCTCCGCTGGAGGTCCCTCACGGATGTCCCTGCTGGAGGCGAGGTGTTAAGTGCCCGCCTC
TGAGCGACAACCGGGGATGT

Product: hypothetical protein

Products: NA

Alternate protein names: 3-dehydroquinate synthase; Unknown phosphatase [H]

Number of amino acids: Translated: 316; Mature: 316

Protein sequence:

>316_residues
MVTGRLAGIDCGTNSIRLLIADVRDGRLRDVHRETRIVRLGQGVDATGEFAPEAIARTRAALSDYADLLKQHGVQRVRMV
ATSAARDVGNRADFFSMTADVLGAVLPGAVAEVITGADEAELSFRGAVGELDSAAGPFVVVDLGGGSTEIVVGGSDGVTA
SHSADIGCVRLTERCLHSDPPTPEEVALARQVVRERLEVALGVVPVEGARTWVGVAGTMTTLSALAHDLPAYDSAAIHLS
RVSGRDLLAVCERLIGMTRAQRAALPPMHAGRADVIAGGAVVVEELARELRARAGIDELTVSEHDILDGIVLSIAG

Sequences:

>Translated_316_residues
MVTGRLAGIDCGTNSIRLLIADVRDGRLRDVHRETRIVRLGQGVDATGEFAPEAIARTRAALSDYADLLKQHGVQRVRMV
ATSAARDVGNRADFFSMTADVLGAVLPGAVAEVITGADEAELSFRGAVGELDSAAGPFVVVDLGGGSTEIVVGGSDGVTA
SHSADIGCVRLTERCLHSDPPTPEEVALARQVVRERLEVALGVVPVEGARTWVGVAGTMTTLSALAHDLPAYDSAAIHLS
RVSGRDLLAVCERLIGMTRAQRAALPPMHAGRADVIAGGAVVVEELARELRARAGIDELTVSEHDILDGIVLSIAG
>Mature_316_residues
MVTGRLAGIDCGTNSIRLLIADVRDGRLRDVHRETRIVRLGQGVDATGEFAPEAIARTRAALSDYADLLKQHGVQRVRMV
ATSAARDVGNRADFFSMTADVLGAVLPGAVAEVITGADEAELSFRGAVGELDSAAGPFVVVDLGGGSTEIVVGGSDGVTA
SHSADIGCVRLTERCLHSDPPTPEEVALARQVVRERLEVALGVVPVEGARTWVGVAGTMTTLSALAHDLPAYDSAAIHLS
RVSGRDLLAVCERLIGMTRAQRAALPPMHAGRADVIAGGAVVVEELARELRARAGIDELTVSEHDILDGIVLSIAG

Specific function: Conversion Of Pppgpp To Ppgpp. Guanosine Pentaphosphate (Pppgpp) Is A Cytoplasmic Signaling Molecule Which Together With Ppgpp Controls The "Stringent Response", An Adaptive Process That Allows Bacteria To Respond To Amino Acid Starvation, Resulting In T

COG id: COG0248

COG function: function code FP; Exopolyphosphatase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the gppA/ppx family [H]

Homologues:

Organism=Escherichia coli, GI48994966, Length=219, Percent_Identity=30.5936073059361, Blast_Score=91, Evalue=9e-20,
Organism=Escherichia coli, GI1788848, Length=215, Percent_Identity=29.3023255813954, Blast_Score=84, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002658
- InterPro:   IPR016037
- InterPro:   IPR003695 [H]

Pfam domain/function: PF01761 DHQ_synthase; PF02541 Ppx-GppA [H]

EC number: =4.2.3.4 [H]

Molecular weight: Translated: 32929; Mature: 32929

Theoretical pI: Translated: 4.97; Mature: 4.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVTGRLAGIDCGTNSIRLLIADVRDGRLRDVHRETRIVRLGQGVDATGEFAPEAIARTRA
CCCCEEEEECCCCCCEEEEEEECCCCHHHHHHHHHHEEEECCCCCCCCCCCHHHHHHHHH
ALSDYADLLKQHGVQRVRMVATSAARDVGNRADFFSMTADVLGAVLPGAVAEVITGADEA
HHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCH
ELSFRGAVGELDSAAGPFVVVDLGGGSTEIVVGGSDGVTASHSADIGCVRLTERCLHSDP
HEEECCCCCCCCCCCCCEEEEEECCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHCCCC
PTPEEVALARQVVRERLEVALGVVPVEGARTWVGVAGTMTTLSALAHDLPAYDSAAIHLS
CCHHHHHHHHHHHHHHHHHHHCCEECCCCCEEEEHHHHHHHHHHHHHHCCCCCCCEEEEE
RVSGRDLLAVCERLIGMTRAQRAALPPMHAGRADVIAGGAVVVEELARELRARAGIDELT
CCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEECHHHHHHHHHHHHHHHCCCCHHC
VSEHDILDGIVLSIAG
CCHHHHHHHHEEEECC
>Mature Secondary Structure
MVTGRLAGIDCGTNSIRLLIADVRDGRLRDVHRETRIVRLGQGVDATGEFAPEAIARTRA
CCCCEEEEECCCCCCEEEEEEECCCCHHHHHHHHHHEEEECCCCCCCCCCCHHHHHHHHH
ALSDYADLLKQHGVQRVRMVATSAARDVGNRADFFSMTADVLGAVLPGAVAEVITGADEA
HHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCH
ELSFRGAVGELDSAAGPFVVVDLGGGSTEIVVGGSDGVTASHSADIGCVRLTERCLHSDP
HEEECCCCCCCCCCCCCEEEEEECCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHCCCC
PTPEEVALARQVVRERLEVALGVVPVEGARTWVGVAGTMTTLSALAHDLPAYDSAAIHLS
CCHHHHHHHHHHHHHHHHHHHCCEECCCCCEEEEHHHHHHHHHHHHHHCCCCCCCEEEEE
RVSGRDLLAVCERLIGMTRAQRAALPPMHAGRADVIAGGAVVVEELARELRARAGIDELT
CCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEECHHHHHHHHHHHHHHHCCCCHHC
VSEHDILDGIVLSIAG
CCHHHHHHHHEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11889109 [H]