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The map label for this gene is gmhB [H]

Identifier: 41407035

GI number: 41407035

Start: 966775

End: 967341

Strand: Direct

Name: gmhB [H]

Synonym: MAP0937

Alternate gene names: 41407035

Gene position: 966775-967341 (Clockwise)

Preceding gene: 41407034

Following gene: 41407036

Centisome position: 20.02

GC content: 71.43

Gene sequence:

>567_bases
ATGCCCGCACCCGAGCTGCGCGACGTCCGCACGGTCTTCCTGGACCGCGACGGCACCGTCAACGTCAAGGCCGCCGAGGG
CGAGTACATCAAGTCGCCGGCCGAGCTGGTGCTGTTGCCCGGTGCGGCCCGGGCGCTGGCCGCGCTGAACGCTGCGGGCC
TGCGGACCGTGTTGGTCACCAATCAGCGCTGGCTCTCCGAGCCGACGGCGGCGCCGGCCGATTTCGCCGCCGTACACGAC
CGGCTGGTACGACTGCTCGCCGACCGGGGCGCGCGCATCGATGCCGCTTACCACTGCCCCCACCCCGCGAACAGCTGCGA
CTGCCGCAAACCCGGCCCCGGCATGCTGTTGCGCGCGGCGGCCGAGCACGACGTGGATTTGGCCGCTTCCGTCATGATCG
GCGACAGCGACGTCGACATGGTGGCGGGCCGCGCGGCCGGAACGAAGACGATTCTGATCCGCCCCGGCGCCCGGCAGGCC
GTCGCAGAGGCCGATTTCGTGGTCGACGACCTGGCCGCGGCCGTCGAACTCATCCTGAATGCCGGAAAAACCCCGCCTGC
CGGGTGA

Upstream 100 bases:

>100_bases
ACGACACCGGCCGGATCCAGGAAGCGAGCCTGCACCTGGGGCATTCGATTTGCGAAATGGTCGAAGCGGCACTGTTTCCC
CGGCCGTCCTGACCGCGACG

Downstream 100 bases:

>100_bases
TCGGCGCTGCCTGCTTGCCGCGGTCGTGACCTGCTCATAACCTTGGCAACATCCGAGCGCGTCGGGGAGCGTGGGGCCTG
GCGCAACCGACAAATGGCGG

Product: hypothetical protein

Products: NA

Alternate protein names: D-glycero-D-manno-heptose 1,7-bisphosphate phosphatase [H]

Number of amino acids: Translated: 188; Mature: 187

Protein sequence:

>188_residues
MPAPELRDVRTVFLDRDGTVNVKAAEGEYIKSPAELVLLPGAARALAALNAAGLRTVLVTNQRWLSEPTAAPADFAAVHD
RLVRLLADRGARIDAAYHCPHPANSCDCRKPGPGMLLRAAAEHDVDLAASVMIGDSDVDMVAGRAAGTKTILIRPGARQA
VAEADFVVDDLAAAVELILNAGKTPPAG

Sequences:

>Translated_188_residues
MPAPELRDVRTVFLDRDGTVNVKAAEGEYIKSPAELVLLPGAARALAALNAAGLRTVLVTNQRWLSEPTAAPADFAAVHD
RLVRLLADRGARIDAAYHCPHPANSCDCRKPGPGMLLRAAAEHDVDLAASVMIGDSDVDMVAGRAAGTKTILIRPGARQA
VAEADFVVDDLAAAVELILNAGKTPPAG
>Mature_187_residues
PAPELRDVRTVFLDRDGTVNVKAAEGEYIKSPAELVLLPGAARALAALNAAGLRTVLVTNQRWLSEPTAAPADFAAVHDR
LVRLLADRGARIDAAYHCPHPANSCDCRKPGPGMLLRAAAEHDVDLAASVMIGDSDVDMVAGRAAGTKTILIRPGARQAV
AEADFVVDDLAAAVELILNAGKTPPAG

Specific function: Converts the D-glycero-beta-D-manno-heptose 1,7- bisphosphate intermediate into D-glycero-beta-D-manno-heptose 1- phosphate by removing the phosphate group at the C-7 position [H]

COG id: COG0241

COG function: function code E; Histidinol phosphatase and related phosphatases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gmhB family [H]

Homologues:

Organism=Escherichia coli, GI1786399, Length=178, Percent_Identity=37.6404494382022, Blast_Score=102, Evalue=1e-23,
Organism=Escherichia coli, GI87082027, Length=139, Percent_Identity=33.0935251798561, Blast_Score=86, Evalue=1e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006549
- InterPro:   IPR004446
- InterPro:   IPR006543 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: NA

Molecular weight: Translated: 19617; Mature: 19485

Theoretical pI: Translated: 5.65; Mature: 5.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPAPELRDVRTVFLDRDGTVNVKAAEGEYIKSPAELVLLPGAARALAALNAAGLRTVLVT
CCCCCCCCEEEEEECCCCEEEEEECCCCCCCCCCEEEEECCHHHHHHHHHHCCEEEEEEE
NQRWLSEPTAAPADFAAVHDRLVRLLADRGARIDAAYHCPHPANSCDCRKPGPGMLLRAA
CCHHHCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCCCCCEEEEC
AEHDVDLAASVMIGDSDVDMVAGRAAGTKTILIRPGARQAVAEADFVVDDLAAAVELILN
CCCCCCEEEEEEECCCCHHHHCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHH
AGKTPPAG
CCCCCCCC
>Mature Secondary Structure 
PAPELRDVRTVFLDRDGTVNVKAAEGEYIKSPAELVLLPGAARALAALNAAGLRTVLVT
CCCCCCCEEEEEECCCCEEEEEECCCCCCCCCCEEEEECCHHHHHHHHHHCCEEEEEEE
NQRWLSEPTAAPADFAAVHDRLVRLLADRGARIDAAYHCPHPANSCDCRKPGPGMLLRAA
CCHHHCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCCCCCEEEEC
AEHDVDLAASVMIGDSDVDMVAGRAAGTKTILIRPGARQAVAEADFVVDDLAAAVELILN
CCCCCCEEEEEEECCCCHHHHCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHH
AGKTPPAG
CCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11248100 [H]