Click here to switch to the map view.

The map label for this gene is gmhA

Identifier: 41407034

GI number: 41407034

Start: 966158

End: 966766

Strand: Direct

Name: gmhA

Synonym: MAP0936

Alternate gene names: 41407034

Gene position: 966158-966766 (Clockwise)

Preceding gene: 41407033

Following gene: 41407035

Centisome position: 20.0

GC content: 69.79

Gene sequence:

>609_bases
ATGACGGGGCCCGATGTGGTGCCGCCGAGCGTGGAGTTGGTGCAGCGGCGACTGGCCGAGACGATCGCGGTCAAGCAGCA
GATGCAGAACGGCGTCGTCGCCGCCCAGGCCGTCGAGGTGGCGCGCGCGATGATCGACTGCCTGCGGGCCGGCGGAAAGG
TGATCCTGTTCGGCAACGGCGGATCCGCGCAGGACGCCGGACATCTGGCCGCAGAACTCATGGGCCGCTTCGCTTTTGAC
CGCCCGGGCCTGGCGGCCATGAGCCTTCCCGACGCCACCGCGGCGATCACCGCGATCGGTAACGACTACTCGTACGACGA
GGTGTTCGCCCGCCAGGTGCTGGCCGCCGGGCGGGCCGGGGACGTGGTGGTCGGGCTGACCACATCGGGCAACTCCGCCA
ACGTCGTTCGCGCGCTCGAGGCCGCCCGCCAGGCCGGGATGACGACCGTCACCCTCACCGGTGCGGGCGGCGGCAAGGTG
GCCGACGTCGCGCAGATCTGCATCCGAATTCCCAGCGACGACACCGGCCGGATCCAGGAAGCGAGCCTGCACCTGGGGCA
TTCGATTTGCGAAATGGTCGAAGCGGCACTGTTTCCCCGGCCGTCCTGA

Upstream 100 bases:

>100_bases
ACTTCGCCAAAAAGCACCGGCTCATCGAGGCGCTGGAAGGCGCCGGGGCCGCCGTCACCGAATTCGCCTTCGAGAGCAAG
GGATTGACGACATGGCAGGC

Downstream 100 bases:

>100_bases
CCGCGACGATGCCCGCACCCGAGCTGCGCGACGTCCGCACGGTCTTCCTGGACCGCGACGGCACCGTCAACGTCAAGGCC
GCCGAGGGCGAGTACATCAA

Product: hypothetical protein

Products: NA

Alternate protein names: Sedoheptulose 7-phosphate isomerase [H]

Number of amino acids: Translated: 202; Mature: 201

Protein sequence:

>202_residues
MTGPDVVPPSVELVQRRLAETIAVKQQMQNGVVAAQAVEVARAMIDCLRAGGKVILFGNGGSAQDAGHLAAELMGRFAFD
RPGLAAMSLPDATAAITAIGNDYSYDEVFARQVLAAGRAGDVVVGLTTSGNSANVVRALEAARQAGMTTVTLTGAGGGKV
ADVAQICIRIPSDDTGRIQEASLHLGHSICEMVEAALFPRPS

Sequences:

>Translated_202_residues
MTGPDVVPPSVELVQRRLAETIAVKQQMQNGVVAAQAVEVARAMIDCLRAGGKVILFGNGGSAQDAGHLAAELMGRFAFD
RPGLAAMSLPDATAAITAIGNDYSYDEVFARQVLAAGRAGDVVVGLTTSGNSANVVRALEAARQAGMTTVTLTGAGGGKV
ADVAQICIRIPSDDTGRIQEASLHLGHSICEMVEAALFPRPS
>Mature_201_residues
TGPDVVPPSVELVQRRLAETIAVKQQMQNGVVAAQAVEVARAMIDCLRAGGKVILFGNGGSAQDAGHLAAELMGRFAFDR
PGLAAMSLPDATAAITAIGNDYSYDEVFARQVLAAGRAGDVVVGLTTSGNSANVVRALEAARQAGMTTVTLTGAGGGKVA
DVAQICIRIPSDDTGRIQEASLHLGHSICEMVEAALFPRPS

Specific function: Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate [H]

COG id: COG0279

COG function: function code G; Phosphoheptose isomerase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SIS domain [H]

Homologues:

Organism=Escherichia coli, GI1786416, Length=190, Percent_Identity=42.6315789473684, Blast_Score=144, Evalue=5e-36,
Organism=Escherichia coli, GI1789539, Length=183, Percent_Identity=39.8907103825137, Blast_Score=133, Evalue=7e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004515
- InterPro:   IPR020620
- InterPro:   IPR001347 [H]

Pfam domain/function: PF01380 SIS [H]

EC number: =5.3.1.28 [H]

Molecular weight: Translated: 20757; Mature: 20626

Theoretical pI: Translated: 5.22; Mature: 5.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGPDVVPPSVELVQRRLAETIAVKQQMQNGVVAAQAVEVARAMIDCLRAGGKVILFGNG
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCEEEEEECC
GSAQDAGHLAAELMGRFAFDRPGLAAMSLPDATAAITAIGNDYSYDEVFARQVLAAGRAG
CCCCHHHHHHHHHHHHHHCCCCCCEEECCCCHHHEEEECCCCCCHHHHHHHHHHHCCCCC
DVVVGLTTSGNSANVVRALEAARQAGMTTVTLTGAGGGKVADVAQICIRIPSDDTGRIQE
CEEEEEECCCCCHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHCCCCCCCCCHHH
ASLHLGHSICEMVEAALFPRPS
HHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
TGPDVVPPSVELVQRRLAETIAVKQQMQNGVVAAQAVEVARAMIDCLRAGGKVILFGNG
CCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCEEEEEECC
GSAQDAGHLAAELMGRFAFDRPGLAAMSLPDATAAITAIGNDYSYDEVFARQVLAAGRAG
CCCCHHHHHHHHHHHHHHCCCCCCEEECCCCHHHEEEECCCCCCHHHHHHHHHHHCCCCC
DVVVGLTTSGNSANVVRALEAARQAGMTTVTLTGAGGGKVADVAQICIRIPSDDTGRIQE
CEEEEEECCCCCHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHCCCCCCCCCHHH
ASLHLGHSICEMVEAALFPRPS
HHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA