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The map label for this gene is sucC

Identifier: 41406994

GI number: 41406994

Start: 923899

End: 925119

Strand: Direct

Name: sucC

Synonym: MAP0896

Alternate gene names: 41406994

Gene position: 923899-925119 (Clockwise)

Preceding gene: 41406991

Following gene: 41406995

Centisome position: 19.13

GC content: 66.83

Gene sequence:

>1221_bases
TTGCGGCACCGCCCACCAAGAGGCCTAGTAGTTGAGTCGAGCGAAGACAGAGAGTCCATGGACCTTTTCGAGTATCAAGC
AAAAGAATTGTTCGCCAAGCACAACGTACCGACCACGCCGGGACGGGTGACCGACACCGCCGAGGGTGCTCGGGACATCG
CCGCCGAGATCGGCCGTCCTGTCATGGTCAAGGCGCAGGTCAAGACCGGTGGCCGCGGCAAGGCGGGCGGCGTGAAATAT
GCCGCCACGCCCGAGGACGCCTACACCCACGCCAAGAACATCCTCGGCCTGGACATCAAGGGCCACGTCGTCAAGAAGCT
GCTGGTGTCCGAGGCCAGCGACATCGCCGAGGAGTACTACATCTCCTTCCTGCTGGACCGCGCCAACCGCACCTACCTGG
CCATGTGCTCGGTCGAGGGCGGCATGGAGATCGAAGAGGTGGCCGCCACCGAGCCTGAGCGGCTGGCCAAGGTGCCGGTG
GACGCCGTCACCGGCGTGGACCTGGCGACCGCGCGGTCCATCGCCGAGAAGGGCCACCTGCCCGCCGAGGTGCTCGACGC
GGCCGCGGTCACCATCAACAAGCTGTGGGAGCTCTTCGTCGCCGAGGACGCCACCCTGGTCGAGGTCAACCCGCTGGTGC
GCACCCCCGACAACCAGATCCTGGCGCTGGACGGCAAGGTCACCCTGGACGCCAACGCCGACTTCCGGCAGCCCGGCCAC
GCCGCGTTCGAGGACCGCGACGCCACCGACCCGCTGGAGCTCAAGGCCAAGGAACACGACCTCAACTACGTGAAGCTGGA
CGGCCAGGTCGGCATCATCGGTAACGGCGCGGGCCTGGCGATGTCCACCCTGGACGTCGTCGCCTACGCGGGCGAGAAGC
ACGGCGGGGTCAAGCCGGCCAACTTCCTCGACATCGGCGGCGGCGCGTCGGCGGAGGTGATGGCCGCGGGCCTGGACGTC
ATCCTGCACGACAAGCAGGTCAAGAGCGTGTTCGTGAACGTGTTCGGCGGTATCACCTCCTGCGACGCCGTCGCCAACGG
CATCGTGACCGCCCTGAACATGCTCGGTGACGAGGCGAACAAGCCGCTGGTGGTTCGGCTCGACGGCAACAACGTCGACC
AGGGTCGCCGCATCCTCGCCGAAGCCAACCACCCGCTGGTGATCCAGGCCGAGACCATGGACTCCGGCGCCGACAAAGCC
GCCGAGCTGGCGAACAAGTAA

Upstream 100 bases:

>100_bases
TAGCCGGTCTATCCGGGTCCCGTGAGCTGTGCCACATCGGCGGACGCGGCGGTAGCAGCGGTTTGGCGGGTGGATACAGT
TCGTCCGTGCGAGTTGCCGA

Downstream 100 bases:

>100_bases
GGGAGCCAAGCCATGTCGATCTTTTTGAACAAGGACTCCAAGGTCATCGTCCAGGGCATCACCGGCGGCGAGGGCACCAA
GCACACCGCGCTGATGCTCA

Product: succinyl-CoA synthetase subunit beta

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit beta; SCS-beta [H]

Number of amino acids: Translated: 406; Mature: 406

Protein sequence:

>406_residues
MRHRPPRGLVVESSEDRESMDLFEYQAKELFAKHNVPTTPGRVTDTAEGARDIAAEIGRPVMVKAQVKTGGRGKAGGVKY
AATPEDAYTHAKNILGLDIKGHVVKKLLVSEASDIAEEYYISFLLDRANRTYLAMCSVEGGMEIEEVAATEPERLAKVPV
DAVTGVDLATARSIAEKGHLPAEVLDAAAVTINKLWELFVAEDATLVEVNPLVRTPDNQILALDGKVTLDANADFRQPGH
AAFEDRDATDPLELKAKEHDLNYVKLDGQVGIIGNGAGLAMSTLDVVAYAGEKHGGVKPANFLDIGGGASAEVMAAGLDV
ILHDKQVKSVFVNVFGGITSCDAVANGIVTALNMLGDEANKPLVVRLDGNNVDQGRRILAEANHPLVIQAETMDSGADKA
AELANK

Sequences:

>Translated_406_residues
MRHRPPRGLVVESSEDRESMDLFEYQAKELFAKHNVPTTPGRVTDTAEGARDIAAEIGRPVMVKAQVKTGGRGKAGGVKY
AATPEDAYTHAKNILGLDIKGHVVKKLLVSEASDIAEEYYISFLLDRANRTYLAMCSVEGGMEIEEVAATEPERLAKVPV
DAVTGVDLATARSIAEKGHLPAEVLDAAAVTINKLWELFVAEDATLVEVNPLVRTPDNQILALDGKVTLDANADFRQPGH
AAFEDRDATDPLELKAKEHDLNYVKLDGQVGIIGNGAGLAMSTLDVVAYAGEKHGGVKPANFLDIGGGASAEVMAAGLDV
ILHDKQVKSVFVNVFGGITSCDAVANGIVTALNMLGDEANKPLVVRLDGNNVDQGRRILAEANHPLVIQAETMDSGADKA
AELANK
>Mature_406_residues
MRHRPPRGLVVESSEDRESMDLFEYQAKELFAKHNVPTTPGRVTDTAEGARDIAAEIGRPVMVKAQVKTGGRGKAGGVKY
AATPEDAYTHAKNILGLDIKGHVVKKLLVSEASDIAEEYYISFLLDRANRTYLAMCSVEGGMEIEEVAATEPERLAKVPV
DAVTGVDLATARSIAEKGHLPAEVLDAAAVTINKLWELFVAEDATLVEVNPLVRTPDNQILALDGKVTLDANADFRQPGH
AAFEDRDATDPLELKAKEHDLNYVKLDGQVGIIGNGAGLAMSTLDVVAYAGEKHGGVKPANFLDIGGGASAEVMAAGLDV
ILHDKQVKSVFVNVFGGITSCDAVANGIVTALNMLGDEANKPLVVRLDGNNVDQGRRILAEANHPLVIQAETMDSGADKA
AELANK

Specific function: Tricarboxylic acid cycle. [C]

COG id: COG0045

COG function: function code C; Succinyl-CoA synthetase, beta subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-grasp domain [H]

Homologues:

Organism=Homo sapiens, GI157779135, Length=385, Percent_Identity=37.6623376623377, Blast_Score=247, Evalue=1e-65,
Organism=Homo sapiens, GI11321583, Length=401, Percent_Identity=35.1620947630923, Blast_Score=244, Evalue=1e-64,
Organism=Homo sapiens, GI294862256, Length=388, Percent_Identity=37.1134020618557, Blast_Score=236, Evalue=3e-62,
Organism=Escherichia coli, GI1786948, Length=376, Percent_Identity=42.5531914893617, Blast_Score=270, Evalue=2e-73,
Organism=Caenorhabditis elegans, GI17539378, Length=401, Percent_Identity=35.4114713216958, Blast_Score=245, Evalue=3e-65,
Organism=Caenorhabditis elegans, GI17567829, Length=403, Percent_Identity=34.9875930521092, Blast_Score=240, Evalue=1e-63,
Organism=Saccharomyces cerevisiae, GI6321683, Length=407, Percent_Identity=35.8722358722359, Blast_Score=240, Evalue=2e-64,
Organism=Drosophila melanogaster, GI21356231, Length=403, Percent_Identity=34.9875930521092, Blast_Score=237, Evalue=8e-63,
Organism=Drosophila melanogaster, GI161078106, Length=414, Percent_Identity=35.024154589372, Blast_Score=231, Evalue=1e-60,
Organism=Drosophila melanogaster, GI24645208, Length=414, Percent_Identity=35.024154589372, Blast_Score=231, Evalue=1e-60,
Organism=Drosophila melanogaster, GI281361397, Length=415, Percent_Identity=34.9397590361446, Blast_Score=227, Evalue=1e-59,
Organism=Drosophila melanogaster, GI281361395, Length=415, Percent_Identity=34.9397590361446, Blast_Score=227, Evalue=1e-59,

Paralogues:

None

Copy number: 340 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2361 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011761
- InterPro:   IPR013650
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR005811
- InterPro:   IPR017866
- InterPro:   IPR005809
- InterPro:   IPR016102 [H]

Pfam domain/function: PF08442 ATP-grasp_2; PF00549 Ligase_CoA [H]

EC number: =6.2.1.5 [H]

Molecular weight: Translated: 43160; Mature: 43160

Theoretical pI: Translated: 4.72; Mature: 4.72

Prosite motif: PS50975 ATP_GRASP ; PS01217 SUCCINYL_COA_LIG_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRHRPPRGLVVESSEDRESMDLFEYQAKELFAKHNVPTTPGRVTDTAEGARDIAAEIGRP
CCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCCC
VMVKAQVKTGGRGKAGGVKYAATPEDAYTHAKNILGLDIKGHVVKKLLVSEASDIAEEYY
EEEEEEECCCCCCCCCCEEEECCCHHHHHHHHHEEEECCHHHHHHHHHHHHHHHHHHHHH
ISFLLDRANRTYLAMCSVEGGMEIEEVAATEPERLAKVPVDAVTGVDLATARSIAEKGHL
HHHHHHCCCCEEEEEEECCCCCCHHHHHCCCHHHHHHCCCHHHCCCHHHHHHHHHHHCCC
PAEVLDAAAVTINKLWELFVAEDATLVEVNPLVRTPDNQILALDGKVTLDANADFRQPGH
CHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCEECCCCCEEEECCEEEECCCCCCCCCCC
AAFEDRDATDPLELKAKEHDLNYVKLDGQVGIIGNGAGLAMSTLDVVAYAGEKHGGVKPA
CCCCCCCCCCCCEEEEECCCCCEEEECCEEEEEECCCCHHHHHHHHHHCCCCCCCCCCCC
NFLDIGGGASAEVMAAGLDVILHDKQVKSVFVNVFGGITSCDAVANGIVTALNMLGDEAN
CEEECCCCCCHHHHHCCCEEEEECHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCC
KPLVVRLDGNNVDQGRRILAEANHPLVIQAETMDSGADKAAELANK
CCEEEEECCCCCCCHHHHHHCCCCCEEEEEECCCCCCHHHHHHHCC
>Mature Secondary Structure
MRHRPPRGLVVESSEDRESMDLFEYQAKELFAKHNVPTTPGRVTDTAEGARDIAAEIGRP
CCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCCC
VMVKAQVKTGGRGKAGGVKYAATPEDAYTHAKNILGLDIKGHVVKKLLVSEASDIAEEYY
EEEEEEECCCCCCCCCCEEEECCCHHHHHHHHHEEEECCHHHHHHHHHHHHHHHHHHHHH
ISFLLDRANRTYLAMCSVEGGMEIEEVAATEPERLAKVPVDAVTGVDLATARSIAEKGHL
HHHHHHCCCCEEEEEEECCCCCCHHHHHCCCHHHHHHCCCHHHCCCHHHHHHHHHHHCCC
PAEVLDAAAVTINKLWELFVAEDATLVEVNPLVRTPDNQILALDGKVTLDANADFRQPGH
CHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCEECCCCCEEEECCEEEECCCCCCCCCCC
AAFEDRDATDPLELKAKEHDLNYVKLDGQVGIIGNGAGLAMSTLDVVAYAGEKHGGVKPA
CCCCCCCCCCCCEEEEECCCCCEEEECCEEEEEECCCCHHHHHHHHHHCCCCCCCCCCCC
NFLDIGGGASAEVMAAGLDVILHDKQVKSVFVNVFGGITSCDAVANGIVTALNMLGDEAN
CEEECCCCCCHHHHHCCCEEEEECHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCC
KPLVVRLDGNNVDQGRRILAEANHPLVIQAETMDSGADKAAELANK
CCEEEEECCCCCCCHHHHHHCCCCCEEEEEECCCCCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA