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The map label for this gene is pbp [H]

Identifier: 41406940

GI number: 41406940

Start: 861215

End: 862801

Strand: Direct

Name: pbp [H]

Synonym: MAP0842

Alternate gene names: 41406940

Gene position: 861215-862801 (Clockwise)

Preceding gene: 41406939

Following gene: 41406941

Centisome position: 17.83

GC content: 68.18

Gene sequence:

>1587_bases
ATGAGCAAACGCGCGGCGGTCCTGACGGCGGTGCTGCTCGGGTTGACCGGATGCGGCTCCGCGCAGCAACCGGCCGGCGC
GCCGCCGCGACCGTCCGACGTCCCGCCCAACCAGGTGTCCGCCCTGGCGATCCCGGCCGGCCGTATCGACGAGGCCGTGG
CGAAGGTGGACGGCCTCGTTGCCGACCTGATGAGAAGCAGCGGCATCCCCGGGATGGCCGTGGCCATCGTGCATGGCGGG
AAGGTGTTGTACGCCAAGGGATTCGGCGTCAAGGATGTGACCAGGGGGCAGGGCCGGGACAACGCGGTGGACACCGACAC
CGTCTTCCAGCTGGCGTCGGTGTCCAAATCGGTGGGCGCGACGGTGGTCGCACACGAAGTCAGCGACCACGTCGTGGGGT
GGGACACGCCCGTGGTTTCCACGCTGCCGTGGTTCGCGCTCGGCGACCCCTACGTCACCGGCCATGTCACCGTCGGCGAT
CTGTACTCGCACCGCTCCGGGCTGCCCGATCATGCGGGCGACAAACTCGAAGATCTGGGCTATGGCCGTCGGCAGATCTG
CGAGCGACTCAGGTTGCTGCCGCTGCGGCCTTTCCGAAACAGCTACGCCTACACCAACTATGGGATCACCGCCGCCGCCG
AGGCGGTGGCGGCCGCGGCCGGCAAAACCTGGGAAGAGCTCTCCGACGAGGTGCTCTACCGCCCGTTGGGAATGACGTCG
ACCAGCTCGCGGTTCGCCGACTTCCTCGCCCGGCCCAACCGCGCGGTCAACCACATCAAGATCGGCGACAGCTGGCAGGC
CCGTTTCCAGCGAAACCCGGACGCCCAGTCACCGGCGGGCGGGGTGAGCTCATCGGTGCACGACATGGCCCGCTGGCTGA
TGATGTTGCTGGACAACGGAACCCACGACGGCCAGCACATCGCATCGCCGGAGGCGCTGCTGCCCGCCCTGAGCCCGCAA
GTGGTGTCCGCCCCCGCGACCACACCGAAGGCGCGCACCGGATTCTACGGATACGGCTTCAACACCTCGGTGGATGCCTC
GGGGCGCACCGAATACAGCCATTCCGGCGCCTTCGATCTGGGCGCAGCCACCAATTTCGTCGTGCTGCCGTCGGAGGACC
TGGCGATCATCGCGTTGACCAACGCCGCGCCCAACGGCATCCCGGAGACGCTGACCGCCGAATTCATGGACCTCGTGCAG
TACGGCCAGATCCGCGAGGACTGGGCCGCCCTGTACCGGAAAGCCATTGGCTGGCTGAACAATCCGCTGGGTTCGCTGGT
GGGCAAGCAGCCGCCGTCCGCCCCCGCGCCGGCCAGGCCGCTGCGCGACTACACCGGCGTCTACGCCAACGACTACTGGG
GCCCGGCCGTGATCAACGAGCACGACGGCGCCCTGCAGTTGACGATGGGCCCGCAACACCGGACCGCCACCCTCACACAC
TGGGACGGCGACACCTTCACCTTCCCGCTGACCGGCGAAAACGCCCCGCCCGGAACGGTTTCCACGGCCACGTTTACCGG
TTCGCCGGCGGCCAGGCTCAACCTGGAGTACTACGACACCGACCAGCTGGGGACGTTCACCCGATGA

Upstream 100 bases:

>100_bases
CGGTGCCGGTCCCCGGTCAGCGCATCGATCCCGCGGCCCCGCAGAAACCCGACCCGTGGTGGCGGCTCTGAATCTGCCGT
CGCCGCGTTAGTGTTCGCGC

Downstream 100 bases:

>100_bases
ACACAGGCCTGACCGACGCCGAGGTGGCCCAGCGGGTCGCGCACGGCCAGCGCAACGCGGTGCGGCAGCGCGCGACGCGC
AGCATCGCCGACATCGTCCG

Product: hypothetical protein

Products: NA

Alternate protein names: PBP-4 [H]

Number of amino acids: Translated: 528; Mature: 527

Protein sequence:

>528_residues
MSKRAAVLTAVLLGLTGCGSAQQPAGAPPRPSDVPPNQVSALAIPAGRIDEAVAKVDGLVADLMRSSGIPGMAVAIVHGG
KVLYAKGFGVKDVTRGQGRDNAVDTDTVFQLASVSKSVGATVVAHEVSDHVVGWDTPVVSTLPWFALGDPYVTGHVTVGD
LYSHRSGLPDHAGDKLEDLGYGRRQICERLRLLPLRPFRNSYAYTNYGITAAAEAVAAAAGKTWEELSDEVLYRPLGMTS
TSSRFADFLARPNRAVNHIKIGDSWQARFQRNPDAQSPAGGVSSSVHDMARWLMMLLDNGTHDGQHIASPEALLPALSPQ
VVSAPATTPKARTGFYGYGFNTSVDASGRTEYSHSGAFDLGAATNFVVLPSEDLAIIALTNAAPNGIPETLTAEFMDLVQ
YGQIREDWAALYRKAIGWLNNPLGSLVGKQPPSAPAPARPLRDYTGVYANDYWGPAVINEHDGALQLTMGPQHRTATLTH
WDGDTFTFPLTGENAPPGTVSTATFTGSPAARLNLEYYDTDQLGTFTR

Sequences:

>Translated_528_residues
MSKRAAVLTAVLLGLTGCGSAQQPAGAPPRPSDVPPNQVSALAIPAGRIDEAVAKVDGLVADLMRSSGIPGMAVAIVHGG
KVLYAKGFGVKDVTRGQGRDNAVDTDTVFQLASVSKSVGATVVAHEVSDHVVGWDTPVVSTLPWFALGDPYVTGHVTVGD
LYSHRSGLPDHAGDKLEDLGYGRRQICERLRLLPLRPFRNSYAYTNYGITAAAEAVAAAAGKTWEELSDEVLYRPLGMTS
TSSRFADFLARPNRAVNHIKIGDSWQARFQRNPDAQSPAGGVSSSVHDMARWLMMLLDNGTHDGQHIASPEALLPALSPQ
VVSAPATTPKARTGFYGYGFNTSVDASGRTEYSHSGAFDLGAATNFVVLPSEDLAIIALTNAAPNGIPETLTAEFMDLVQ
YGQIREDWAALYRKAIGWLNNPLGSLVGKQPPSAPAPARPLRDYTGVYANDYWGPAVINEHDGALQLTMGPQHRTATLTH
WDGDTFTFPLTGENAPPGTVSTATFTGSPAARLNLEYYDTDQLGTFTR
>Mature_527_residues
SKRAAVLTAVLLGLTGCGSAQQPAGAPPRPSDVPPNQVSALAIPAGRIDEAVAKVDGLVADLMRSSGIPGMAVAIVHGGK
VLYAKGFGVKDVTRGQGRDNAVDTDTVFQLASVSKSVGATVVAHEVSDHVVGWDTPVVSTLPWFALGDPYVTGHVTVGDL
YSHRSGLPDHAGDKLEDLGYGRRQICERLRLLPLRPFRNSYAYTNYGITAAAEAVAAAAGKTWEELSDEVLYRPLGMTST
SSRFADFLARPNRAVNHIKIGDSWQARFQRNPDAQSPAGGVSSSVHDMARWLMMLLDNGTHDGQHIASPEALLPALSPQV
VSAPATTPKARTGFYGYGFNTSVDASGRTEYSHSGAFDLGAATNFVVLPSEDLAIIALTNAAPNGIPETLTAEFMDLVQY
GQIREDWAALYRKAIGWLNNPLGSLVGKQPPSAPAPARPLRDYTGVYANDYWGPAVINEHDGALQLTMGPQHRTATLTHW
DGDTFTFPLTGENAPPGTVSTATFTGSPAARLNLEYYDTDQLGTFTR

Specific function: Involved in cell wall biosynthesis and may also act as a sensor of external penicillins [H]

COG id: COG1680

COG function: function code V; Beta-lactamase class C and other penicillin binding proteins

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the beta-lactamase family [H]

Homologues:

Organism=Caenorhabditis elegans, GI115533026, Length=370, Percent_Identity=25.1351351351351, Blast_Score=74, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR001466 [H]

Pfam domain/function: PF00144 Beta-lactamase [H]

EC number: NA

Molecular weight: Translated: 56164; Mature: 56033

Theoretical pI: Translated: 6.15; Mature: 6.15

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKRAAVLTAVLLGLTGCGSAQQPAGAPPRPSDVPPNQVSALAIPAGRIDEAVAKVDGLV
CCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHH
ADLMRSSGIPGMAVAIVHGGKVLYAKGFGVKDVTRGQGRDNAVDTDTVFQLASVSKSVGA
HHHHHHCCCCCEEEEEEECCEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCC
TVVAHEVSDHVVGWDTPVVSTLPWFALGDPYVTGHVTVGDLYSHRSGLPDHAGDKLEDLG
EEEEEHHCCCCCCCCCCHHHHCCHHCCCCCEEEEEEEHHHHHHHCCCCCCCCCCHHHHCC
YGRRQICERLRLLPLRPFRNSYAYTNYGITAAAEAVAAAAGKTWEELSDEVLYRPLGMTS
CCHHHHHHHHHCCCCCCCCCCCCEECCCHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCC
TSSRFADFLARPNRAVNHIKIGDSWQARFQRNPDAQSPAGGVSSSVHDMARWLMMLLDNG
CHHHHHHHHHCCCCCCCEEEECCCHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCC
THDGQHIASPEALLPALSPQVVSAPATTPKARTGFYGYGFNTSVDASGRTEYSHSGAFDL
CCCCCCCCCCHHHHHCCCCCCEECCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCEEC
GAATNFVVLPSEDLAIIALTNAAPNGIPETLTAEFMDLVQYGQIREDWAALYRKAIGWLN
CCCCCEEEECCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHC
NPLGSLVGKQPPSAPAPARPLRDYTGVYANDYWGPAVINEHDGALQLTMGPQHRTATLTH
CCHHHHHCCCCCCCCCCCCCHHHHCCCCCCCCCCCCEEECCCCEEEEEECCCCCEEEEEE
WDGDTFTFPLTGENAPPGTVSTATFTGSPAARLNLEYYDTDQLGTFTR
ECCCEEEEEECCCCCCCCCEEEEEECCCCCEEEEEEEECCCCCCCCCC
>Mature Secondary Structure 
SKRAAVLTAVLLGLTGCGSAQQPAGAPPRPSDVPPNQVSALAIPAGRIDEAVAKVDGLV
CCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHH
ADLMRSSGIPGMAVAIVHGGKVLYAKGFGVKDVTRGQGRDNAVDTDTVFQLASVSKSVGA
HHHHHHCCCCCEEEEEEECCEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCC
TVVAHEVSDHVVGWDTPVVSTLPWFALGDPYVTGHVTVGDLYSHRSGLPDHAGDKLEDLG
EEEEEHHCCCCCCCCCCHHHHCCHHCCCCCEEEEEEEHHHHHHHCCCCCCCCCCHHHHCC
YGRRQICERLRLLPLRPFRNSYAYTNYGITAAAEAVAAAAGKTWEELSDEVLYRPLGMTS
CCHHHHHHHHHCCCCCCCCCCCCEECCCHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCC
TSSRFADFLARPNRAVNHIKIGDSWQARFQRNPDAQSPAGGVSSSVHDMARWLMMLLDNG
CHHHHHHHHHCCCCCCCEEEECCCHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCC
THDGQHIASPEALLPALSPQVVSAPATTPKARTGFYGYGFNTSVDASGRTEYSHSGAFDL
CCCCCCCCCCHHHHHCCCCCCEECCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCEEC
GAATNFVVLPSEDLAIIALTNAAPNGIPETLTAEFMDLVQYGQIREDWAALYRKAIGWLN
CCCCCEEEECCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHC
NPLGSLVGKQPPSAPAPARPLRDYTGVYANDYWGPAVINEHDGALQLTMGPQHRTATLTH
CCHHHHHCCCCCCCCCCCCCHHHHCCCCCCCCCCCCEEECCCCEEEEEECCCCCEEEEEE
WDGDTFTFPLTGENAPPGTVSTATFTGSPAARLNLEYYDTDQLGTFTR
ECCCEEEEEECCCCCCCCCEEEEEECCCCCEEEEEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8440253 [H]