Click here to switch to the map view.

The map label for this gene is mer [H]

Identifier: 41406835

GI number: 41406835

Start: 759775

End: 760731

Strand: Direct

Name: mer [H]

Synonym: MAP0737

Alternate gene names: 41406835

Gene position: 759775-760731 (Clockwise)

Preceding gene: 41406834

Following gene: 41406837

Centisome position: 15.73

GC content: 70.01

Gene sequence:

>957_bases
GTGCGAATCGGATTGATGGTCGGCTCGGACAAGGAGCGGACGCGTGCTGAGCGGCTGGCCGGGCTGGTCGACGACGCGGC
CACCGCCGAACGCGGCGGTTTCACCGCGTTCTGGATGCCCCAGGTGCCCGGCTACCTCGACGCGCTCACCGCGGTGGCGC
TGATCGGGCAGGCCACCGAGCGCATCGAGATCGGAACGGCGGTGGTCCCGATCCAGACCCGCCACCCGATGGCCCTGGCG
CAGCAGGCATTGACCACCCAGGTCGCCTGCGGCGGGCGGTTCACGTTGGGCATCGGGCCCTCGCATCACTGGATCGTCAA
CGGCCAACTGGGACTGCCCTATGAACGTCCGGCACGCCTGACGAGGAACTACCTGCAGGTGCTCGGCGCGGCGTTCGCCG
GACCGGGCAGCGTCGACGTCGACAACGAAAGTTATTGCGTGCATTCGCCGGTCGACGTCACGGATTCATTCGGTGTCTCG
ATCCTGTTGTCGGCGCTGGGGCCGACGATGCTGCAACTGGCGGGCGAGCGCGCCGACGGCACCATACTGTGGATGGCCGA
CGAGCGGGCGATCGGCGACCATGTGGTGCCGCGGATCACCGCGGCGGCCGGCGGTGCCGGACGGCCGGCGCCTCGAGTCG
TCGCCGGGGTTCCGGTCGCAGTCTGCTCGAACAGCGAGATCGACGATGCGCGAGCCTATGCCGGCGAGATGCTCGGTCAC
GCGGAGTTCTCCCCGAATTACGTCCGGCTGCTGCAGCACGGCGACGCCGAAGACGTCGGCGACACCATGGCGGCCGGCGA
CGAGTCGGCCGTGCTGCGCAGGTTGCGGCGGTACCGCGACGCGGGCGCTACCGACCTGGCGGCGCGGATCGTGCCACTGG
GCAACGACGCGCGCGAGCGGGCCGAATCGCGGCGCCGCACTCACGAATTCCTGTCGTCGGTGTGCCCGGCGTTGTGA

Upstream 100 bases:

>100_bases
GCGCTGGGCCGACGCGGGCGTCGAACCCCTGTTTGCCGCACCGTTTTTCGCGGTGGTGCCCTACGAATGGGATCGCTATG
TCCCGTAGCCGGGGGGCGGC

Downstream 100 bases:

>100_bases
GGCTCAGCGGGTGAAGCCCCACTCTGCTTCGTTCTCTTCGGTTTTCAGGTGCTCCGCCGGATCCGTCGCCTCGGCCAGCG
GTGGGCGATGGGAAGGGGCG

Product: hypothetical protein

Products: NA

Alternate protein names: Coenzyme F420-dependent N(5),N(10)-methylenetetrahydromethanopterin reductase; Methylene-H(4)MPT reductase [H]

Number of amino acids: Translated: 318; Mature: 318

Protein sequence:

>318_residues
MRIGLMVGSDKERTRAERLAGLVDDAATAERGGFTAFWMPQVPGYLDALTAVALIGQATERIEIGTAVVPIQTRHPMALA
QQALTTQVACGGRFTLGIGPSHHWIVNGQLGLPYERPARLTRNYLQVLGAAFAGPGSVDVDNESYCVHSPVDVTDSFGVS
ILLSALGPTMLQLAGERADGTILWMADERAIGDHVVPRITAAAGGAGRPAPRVVAGVPVAVCSNSEIDDARAYAGEMLGH
AEFSPNYVRLLQHGDAEDVGDTMAAGDESAVLRRLRRYRDAGATDLAARIVPLGNDARERAESRRRTHEFLSSVCPAL

Sequences:

>Translated_318_residues
MRIGLMVGSDKERTRAERLAGLVDDAATAERGGFTAFWMPQVPGYLDALTAVALIGQATERIEIGTAVVPIQTRHPMALA
QQALTTQVACGGRFTLGIGPSHHWIVNGQLGLPYERPARLTRNYLQVLGAAFAGPGSVDVDNESYCVHSPVDVTDSFGVS
ILLSALGPTMLQLAGERADGTILWMADERAIGDHVVPRITAAAGGAGRPAPRVVAGVPVAVCSNSEIDDARAYAGEMLGH
AEFSPNYVRLLQHGDAEDVGDTMAAGDESAVLRRLRRYRDAGATDLAARIVPLGNDARERAESRRRTHEFLSSVCPAL
>Mature_318_residues
MRIGLMVGSDKERTRAERLAGLVDDAATAERGGFTAFWMPQVPGYLDALTAVALIGQATERIEIGTAVVPIQTRHPMALA
QQALTTQVACGGRFTLGIGPSHHWIVNGQLGLPYERPARLTRNYLQVLGAAFAGPGSVDVDNESYCVHSPVDVTDSFGVS
ILLSALGPTMLQLAGERADGTILWMADERAIGDHVVPRITAAAGGAGRPAPRVVAGVPVAVCSNSEIDDARAYAGEMLGH
AEFSPNYVRLLQHGDAEDVGDTMAAGDESAVLRRLRRYRDAGATDLAARIVPLGNDARERAESRRRTHEFLSSVCPAL

Specific function: Catalyzes the reversible reduction of methylene-H(4)MPT to methyl-H(4)MPT [H]

COG id: COG2141

COG function: function code C; Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mer family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011251
- InterPro:   IPR016048
- InterPro:   IPR019946 [H]

Pfam domain/function: PF00296 Bac_luciferase [H]

EC number: =1.5.99.11 [H]

Molecular weight: Translated: 33788; Mature: 33788

Theoretical pI: Translated: 5.86; Mature: 5.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIGLMVGSDKERTRAERLAGLVDDAATAERGGFTAFWMPQVPGYLDALTAVALIGQATE
CEEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHHHHHH
RIEIGTAVVPIQTRHPMALAQQALTTQVACGGRFTLGIGPSHHWIVNGQLGLPYERPARL
HEEECEEEEEECCCCCHHHHHHHHHHHHCCCCEEEEECCCCCEEEEECCCCCCCCCHHHH
TRNYLQVLGAAFAGPGSVDVDNESYCVHSPVDVTDSFGVSILLSALGPTMLQLAGERADG
HHHHHHHHHHHHCCCCCCCCCCCCEEEECCCCCCCHHHHHHHHHHHCHHHHHHHCCCCCC
TILWMADERAIGDHVVPRITAAAGGAGRPAPRVVAGVPVAVCSNSEIDDARAYAGEMLGH
EEEEEECCCCCCCHHHHHHHHCCCCCCCCCCCEEECCCEEEECCCCCHHHHHHHHHHHCC
AEFSPNYVRLLQHGDAEDVGDTMAAGDESAVLRRLRRYRDAGATDLAARIVPLGNDARER
CCCCCHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHEEEECCCHHHHH
AESRRRTHEFLSSVCPAL
HHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MRIGLMVGSDKERTRAERLAGLVDDAATAERGGFTAFWMPQVPGYLDALTAVALIGQATE
CEEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHHHHHH
RIEIGTAVVPIQTRHPMALAQQALTTQVACGGRFTLGIGPSHHWIVNGQLGLPYERPARL
HEEECEEEEEECCCCCHHHHHHHHHHHHCCCCEEEEECCCCCEEEEECCCCCCCCCHHHH
TRNYLQVLGAAFAGPGSVDVDNESYCVHSPVDVTDSFGVSILLSALGPTMLQLAGERADG
HHHHHHHHHHHHCCCCCCCCCCCCEEEECCCCCCCHHHHHHHHHHHCHHHHHHHCCCCCC
TILWMADERAIGDHVVPRITAAAGGAGRPAPRVVAGVPVAVCSNSEIDDARAYAGEMLGH
EEEEEECCCCCCCHHHHHHHHCCCCCCCCCCCEEECCCEEEECCCCCHHHHHHHHHHHCC
AEFSPNYVRLLQHGDAEDVGDTMAAGDESAVLRRLRRYRDAGATDLAARIVPLGNDARER
CCCCCHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHEEEECCCHHHHH
AESRRRTHEFLSSVCPAL
HHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11932238 [H]