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The map label for this gene is ftsY

Identifier: 52842876

GI number: 52842876

Start: 3016947

End: 3018053

Strand: Reverse

Name: ftsY

Synonym: lpg2670

Alternate gene names: 52842876

Gene position: 3018053-3016947 (Counterclockwise)

Preceding gene: 52842884

Following gene: 52842875

Centisome position: 88.82

GC content: 42.91

Gene sequence:

>1107_bases
ATGATAGAATTTCATATTTTTAAGGAATTGTACACTAAAATGATTAAATGGTTTAAACGAAATCAAAATTCCGAACCAAA
TTTGGATGCCGAAGAGCAACAAGATCATGCCAAAAGCAGCATGGAATCCAGGCTTGAAGAACCCCAGGAACTGACTGTCA
AAGAGCCTTCGCCCAAAGAAAGTATTTTTGCCCGGTTTAGGAAAGGCCTTAGCAAAACCCGTCATCAATTGGGGGAAGGC
ATAAGTCGGCTGCTGTTAGGTAAAAAAGAAATCAGCCAGGAGTTACTCGAAGAGCTAGAGACCTTATTAATTAGTGCTGA
TTTAGGTTTGGACACCACTCAAGACGTATTGAAACAGCTAAATGAAGGCTTGGCACGAAAGCAACTGTCTAATGGTGAAG
CAGTTTATCTGACTCTAAAGACAAATTTGCAAACTATTTTGAGCCAGGAAGAGAAACCGCTTTCCATAGAAACTGAAGAC
GGCTCTCCCTTTGTCATATTAATGGTTGGTGTCAATGGAGCCGGTAAAACAACCACGATTGGTAAACTAGCCAAACAATT
CCAAAAGCAGGGAAAAAAAGTCATGTTAGCTGCGGGCGATACGTTTCGGGCGGCTGCGGTGGAACAATTGCATGTATGGG
GCGAAAGAAATGGCATACCTGTTATTGCCCAGCATACCGGCGCTGACAGTGCCTCAGTAATATTTGATGCTCTTCAGGCT
GCCAAAGCGAGAAAAATAGATGTTTTAATCGCTGATACAGCCGGGCGTTTGCATACTCAAAGCAATTTAATGGAAGAGTT
GAAAAAAGTGAAAAGAGTCATGCAGAAACTCGATCCCAAGGCACCTCATGAAACCATGTTGGTATTGGATGCGAGTATTG
GGCAGAACGCCTTGGCTCAGGCAAAGCAGTTTCATGAAGCAGTACAATTAACTGGAATTACTATGACCAAGCTTGATGGG
ACAGCCAAAGGCGGGATATTATTTGCTATAGCGAATGATTTGGGGATACCTTTTCGTTATTTAGGGGTAGGGGAGGGCAT
TGAAGATTTGAGGCCCTTTGACGCAGCGCAATTTGTTAGTGCGATATTCGATGATGATCACATTTGA

Upstream 100 bases:

>100_bases
TTTAACGTATACTCCTGGACTTGGCTAAAAGCCTGAAATGAGAGTAGCATCATAAGAGAAATGAGTAATTTGTGCACAAT
GTCACCTCAAAGCTAAAAAG

Downstream 100 bases:

>100_bases
CCAGGTTAGTAAACGTTATCCGGGGGGCTTTGAGGCATTAAGCCAAGTTAATTTTTCTTTGCAAAAAGGAGAAATGGTCT
TTCTTACTGGCCATTCAGGT

Product: cell division membrane protein FtsY

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 368; Mature: 368

Protein sequence:

>368_residues
MIEFHIFKELYTKMIKWFKRNQNSEPNLDAEEQQDHAKSSMESRLEEPQELTVKEPSPKESIFARFRKGLSKTRHQLGEG
ISRLLLGKKEISQELLEELETLLISADLGLDTTQDVLKQLNEGLARKQLSNGEAVYLTLKTNLQTILSQEEKPLSIETED
GSPFVILMVGVNGAGKTTTIGKLAKQFQKQGKKVMLAAGDTFRAAAVEQLHVWGERNGIPVIAQHTGADSASVIFDALQA
AKARKIDVLIADTAGRLHTQSNLMEELKKVKRVMQKLDPKAPHETMLVLDASIGQNALAQAKQFHEAVQLTGITMTKLDG
TAKGGILFAIANDLGIPFRYLGVGEGIEDLRPFDAAQFVSAIFDDDHI

Sequences:

>Translated_368_residues
MIEFHIFKELYTKMIKWFKRNQNSEPNLDAEEQQDHAKSSMESRLEEPQELTVKEPSPKESIFARFRKGLSKTRHQLGEG
ISRLLLGKKEISQELLEELETLLISADLGLDTTQDVLKQLNEGLARKQLSNGEAVYLTLKTNLQTILSQEEKPLSIETED
GSPFVILMVGVNGAGKTTTIGKLAKQFQKQGKKVMLAAGDTFRAAAVEQLHVWGERNGIPVIAQHTGADSASVIFDALQA
AKARKIDVLIADTAGRLHTQSNLMEELKKVKRVMQKLDPKAPHETMLVLDASIGQNALAQAKQFHEAVQLTGITMTKLDG
TAKGGILFAIANDLGIPFRYLGVGEGIEDLRPFDAAQFVSAIFDDDHI
>Mature_368_residues
MIEFHIFKELYTKMIKWFKRNQNSEPNLDAEEQQDHAKSSMESRLEEPQELTVKEPSPKESIFARFRKGLSKTRHQLGEG
ISRLLLGKKEISQELLEELETLLISADLGLDTTQDVLKQLNEGLARKQLSNGEAVYLTLKTNLQTILSQEEKPLSIETED
GSPFVILMVGVNGAGKTTTIGKLAKQFQKQGKKVMLAAGDTFRAAAVEQLHVWGERNGIPVIAQHTGADSASVIFDALQA
AKARKIDVLIADTAGRLHTQSNLMEELKKVKRVMQKLDPKAPHETMLVLDASIGQNALAQAKQFHEAVQLTGITMTKLDG
TAKGGILFAIANDLGIPFRYLGVGEGIEDLRPFDAAQFVSAIFDDDHI

Specific function: Functional homolog of SRP receptor. Probably involved in the reception and insertion of a subset of proteins at the cytoplasmic membrane. Binds to the ribosome in the presence of the SRP particle and a non-hydrolyzable GTP analog. This abolishes trigger f

COG id: COG0552

COG function: function code U; Signal recognition particle GTPase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP-binding SRP family [H]

Homologues:

Organism=Homo sapiens, GI4507215, Length=280, Percent_Identity=30.7142857142857, Blast_Score=137, Evalue=1e-32,
Organism=Homo sapiens, GI226371618, Length=203, Percent_Identity=36.4532019704434, Blast_Score=134, Evalue=2e-31,
Organism=Homo sapiens, GI23308697, Length=332, Percent_Identity=27.710843373494, Blast_Score=107, Evalue=3e-23,
Organism=Homo sapiens, GI295424842, Length=332, Percent_Identity=27.710843373494, Blast_Score=106, Evalue=3e-23,
Organism=Homo sapiens, GI89061728, Length=143, Percent_Identity=32.1678321678322, Blast_Score=84, Evalue=2e-16,
Organism=Escherichia coli, GI1789874, Length=310, Percent_Identity=65.1612903225806, Blast_Score=394, Evalue=1e-111,
Organism=Escherichia coli, GI1788963, Length=276, Percent_Identity=35.1449275362319, Blast_Score=168, Evalue=6e-43,
Organism=Caenorhabditis elegans, GI17539958, Length=269, Percent_Identity=28.2527881040892, Blast_Score=119, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI193206261, Length=311, Percent_Identity=29.5819935691318, Blast_Score=115, Evalue=5e-26,
Organism=Saccharomyces cerevisiae, GI6325345, Length=250, Percent_Identity=35.2, Blast_Score=142, Evalue=7e-35,
Organism=Saccharomyces cerevisiae, GI6320498, Length=330, Percent_Identity=27.5757575757576, Blast_Score=104, Evalue=2e-23,
Organism=Drosophila melanogaster, GI17647949, Length=203, Percent_Identity=35.9605911330049, Blast_Score=129, Evalue=3e-30,
Organism=Drosophila melanogaster, GI24641198, Length=316, Percent_Identity=25.9493670886076, Blast_Score=101, Evalue=9e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004390
- InterPro:   IPR003593
- InterPro:   IPR000897
- InterPro:   IPR013822 [H]

Pfam domain/function: PF00448 SRP54; PF02881 SRP54_N [H]

EC number: NA

Molecular weight: Translated: 40681; Mature: 40681

Theoretical pI: Translated: 6.26; Mature: 6.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIEFHIFKELYTKMIKWFKRNQNSEPNLDAEEQQDHAKSSMESRLEEPQELTVKEPSPKE
CCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHH
SIFARFRKGLSKTRHQLGEGISRLLLGKKEISQELLEELETLLISADLGLDTTQDVLKQL
HHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHH
NEGLARKQLSNGEAVYLTLKTNLQTILSQEEKPLSIETEDGSPFVILMVGVNGAGKTTTI
HHHHHHHHCCCCCEEEEEEECCHHHHHCCCCCCCEEEECCCCCEEEEEEECCCCCCCHHH
GKLAKQFQKQGKKVMLAAGDTFRAAAVEQLHVWGERNGIPVIAQHTGADSASVIFDALQA
HHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHH
AKARKIDVLIADTAGRLHTQSNLMEELKKVKRVMQKLDPKAPHETMLVLDASIGQNALAQ
HHCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCHHHHHH
AKQFHEAVQLTGITMTKLDGTAKGGILFAIANDLGIPFRYLGVGEGIEDLRPFDAAQFVS
HHHHHHHHHHCCEEEEECCCCCCCCEEEEEECCCCCCEEEEECCCCHHHCCCCCHHHHHH
AIFDDDHI
HHHCCCCC
>Mature Secondary Structure
MIEFHIFKELYTKMIKWFKRNQNSEPNLDAEEQQDHAKSSMESRLEEPQELTVKEPSPKE
CCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHH
SIFARFRKGLSKTRHQLGEGISRLLLGKKEISQELLEELETLLISADLGLDTTQDVLKQL
HHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHH
NEGLARKQLSNGEAVYLTLKTNLQTILSQEEKPLSIETEDGSPFVILMVGVNGAGKTTTI
HHHHHHHHCCCCCEEEEEEECCHHHHHCCCCCCCEEEECCCCCEEEEEEECCCCCCCHHH
GKLAKQFQKQGKKVMLAAGDTFRAAAVEQLHVWGERNGIPVIAQHTGADSASVIFDALQA
HHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHH
AKARKIDVLIADTAGRLHTQSNLMEELKKVKRVMQKLDPKAPHETMLVLDASIGQNALAQ
HHCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCHHHHHH
AKQFHEAVQLTGITMTKLDGTAKGGILFAIANDLGIPFRYLGVGEGIEDLRPFDAAQFVS
HHHHHHHHHHCCEEEEECCCCCCCCEEEEEECCCCCCEEEEECCCCHHHCCCCCHHHHHH
AIFDDDHI
HHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3025556; 8041620; 9278503; 2161989; 8194520; 9002525 [H]