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The map label for this gene is cfa

Identifier: 52841365

GI number: 52841365

Start: 1246993

End: 1248159

Strand: Reverse

Name: cfa

Synonym: lpg1131

Alternate gene names: 52841365

Gene position: 1248159-1246993 (Counterclockwise)

Preceding gene: 52841366

Following gene: 52841364

Centisome position: 36.73

GC content: 35.9

Gene sequence:

>1167_bases
TTGAATGTTTCAACATCCTTTATAAAAAGGGAGTTTGATATGGATATTAAAAAAAACAAAGCAAAAATATTTGTTAATTA
CATGCTTCAGCTAGCCAATATCAATATCAATGGCCAAACACCTTGGGATATACAAATTTATAATGATGAGTTCTATTCCA
GATTATTGCGTGATGCCGATTTGGGTCTGGGTGAAAGTTACATGGACGGTTGGTGGGATTGTCAACGAATTGATTTATTT
ATTTCAAAACTGATTAACGCAAATCTTGAGTCCAAAATTAAAATTAATTTTAAATTGGCATTTAATGTCTTTTTATCAAA
AATATTGAACCTGCAAACCCAAAAACGTTCTCTACATGTTGGTAGACAACATTATGATAGAGGAAATGATCTGTTTCAGA
TTATGCTTGATAGCAACATGAACTACACTTGCGGTTATTGGAGAAAAGCTGAAAATTTGGAGCAAGCCCAACTCGACAAG
CTCGATCTGACCTGCAGAAAACTCTGCCTTAAACCCGGTATGAAATTGCTGGATATCGGATGTGGATGGGGAGGACTTGC
AAAATATGCTGCTGAAAACTATGGGGTATCAGTAGTTGGCATAACGATATCACAGCAACAATACGAGTTAGCTAAAACGC
GCTGTGCTCATTTGCCTGTTGAAATCCGATTTCAGGATTATAGAGACTTAAATGAAAAATTCGATCGTATAGTCTCCTTA
GGGATGTTTGAGCATGTTGGTTACAAGAATTACCGAAAATACATGGAGATTGTCCATCAATGTTTAAATGATGATGGTTT
GTTCATATTACACACTATAGGTTCCAATGAAAGTGTCACAAAAGCCACACCCTGGATTTCAAAATATATTTTTCCCAATG
GAATGATTCCATCCATCATGCAAATAGGCCAAGCTTCCGAAAAATTATTCGTTATGGAAGATTGGCATAATTTTGGAGCT
GATTATTACAAAACATTAATGGCATGGCATGAGAATTTCAATAAGGGATGGGACCAAATTAAATCCCAATATAGCGAAAA
ATTCTTTCGTATGTGGAATTATTATTTGCTCTCTTGTGCTGGCGCTTTTGATGCCAGAATGTTGCAATTATGGCAGATTG
TTTTTTCAAAGAAAGGAATTCAAGGAGGTTACTCTGCGCCGAGGTAA

Upstream 100 bases:

>100_bases
TTTTGCCCTTGATTTCGATTGTGTTGTTTTTTCTGATTATTATTTATTATCTTGTTACAGCCATAACAGACGCTTTGAGT
GGCTGATGATGTTGCATTGA

Downstream 100 bases:

>100_bases
ATGGTTTAAACGATTTATTCCGTATCGTAATACCTTCACCAGCAAACCTGGTTTTCCATGCCATGAAGTTGGCAAGATTA
TTCATATATCCCGTTAATTT

Product: cyclopropane fatty acyl phospholipid synthase

Products: NA

Alternate protein names: CFA synthase; Cyclopropane fatty acid synthase [H]

Number of amino acids: Translated: 388; Mature: 388

Protein sequence:

>388_residues
MNVSTSFIKREFDMDIKKNKAKIFVNYMLQLANININGQTPWDIQIYNDEFYSRLLRDADLGLGESYMDGWWDCQRIDLF
ISKLINANLESKIKINFKLAFNVFLSKILNLQTQKRSLHVGRQHYDRGNDLFQIMLDSNMNYTCGYWRKAENLEQAQLDK
LDLTCRKLCLKPGMKLLDIGCGWGGLAKYAAENYGVSVVGITISQQQYELAKTRCAHLPVEIRFQDYRDLNEKFDRIVSL
GMFEHVGYKNYRKYMEIVHQCLNDDGLFILHTIGSNESVTKATPWISKYIFPNGMIPSIMQIGQASEKLFVMEDWHNFGA
DYYKTLMAWHENFNKGWDQIKSQYSEKFFRMWNYYLLSCAGAFDARMLQLWQIVFSKKGIQGGYSAPR

Sequences:

>Translated_388_residues
MNVSTSFIKREFDMDIKKNKAKIFVNYMLQLANININGQTPWDIQIYNDEFYSRLLRDADLGLGESYMDGWWDCQRIDLF
ISKLINANLESKIKINFKLAFNVFLSKILNLQTQKRSLHVGRQHYDRGNDLFQIMLDSNMNYTCGYWRKAENLEQAQLDK
LDLTCRKLCLKPGMKLLDIGCGWGGLAKYAAENYGVSVVGITISQQQYELAKTRCAHLPVEIRFQDYRDLNEKFDRIVSL
GMFEHVGYKNYRKYMEIVHQCLNDDGLFILHTIGSNESVTKATPWISKYIFPNGMIPSIMQIGQASEKLFVMEDWHNFGA
DYYKTLMAWHENFNKGWDQIKSQYSEKFFRMWNYYLLSCAGAFDARMLQLWQIVFSKKGIQGGYSAPR
>Mature_388_residues
MNVSTSFIKREFDMDIKKNKAKIFVNYMLQLANININGQTPWDIQIYNDEFYSRLLRDADLGLGESYMDGWWDCQRIDLF
ISKLINANLESKIKINFKLAFNVFLSKILNLQTQKRSLHVGRQHYDRGNDLFQIMLDSNMNYTCGYWRKAENLEQAQLDK
LDLTCRKLCLKPGMKLLDIGCGWGGLAKYAAENYGVSVVGITISQQQYELAKTRCAHLPVEIRFQDYRDLNEKFDRIVSL
GMFEHVGYKNYRKYMEIVHQCLNDDGLFILHTIGSNESVTKATPWISKYIFPNGMIPSIMQIGQASEKLFVMEDWHNFGA
DYYKTLMAWHENFNKGWDQIKSQYSEKFFRMWNYYLLSCAGAFDARMLQLWQIVFSKKGIQGGYSAPR

Specific function: Transfers a methylene group from S-adenosyl-L-methionine to the cis double bond of an unsaturated fatty acid chain resulting in the replacement of the double bond with a methylene bridge [H]

COG id: COG2230

COG function: function code M; Cyclopropane fatty acid synthase and related methyltransferases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CFA/CMAS family [H]

Homologues:

Organism=Escherichia coli, GI1787951, Length=364, Percent_Identity=56.3186813186813, Blast_Score=442, Evalue=1e-125,
Organism=Caenorhabditis elegans, GI133904226, Length=423, Percent_Identity=29.3144208037825, Blast_Score=161, Evalue=6e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003333 [H]

Pfam domain/function: PF02353 CMAS [H]

EC number: =2.1.1.79 [H]

Molecular weight: Translated: 45413; Mature: 45413

Theoretical pI: Translated: 8.64; Mature: 8.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNVSTSFIKREFDMDIKKNKAKIFVNYMLQLANININGQTPWDIQIYNDEFYSRLLRDAD
CCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHEEEECCCCCEEEEEECHHHHHHHHHHCC
LGLGESYMDGWWDCQRIDLFISKLINANLESKIKINFKLAFNVFLSKILNLQTQKRSLHV
CCCCCHHHCCCCCHHHHHHHHHHHHCCCCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHHH
GRQHYDRGNDLFQIMLDSNMNYTCGYWRKAENLEQAQLDKLDLTCRKLCLKPGMKLLDIG
HHHHHCCCCCEEEEEECCCCCCEECCCHHHCCCCHHHHHHHHHHHHHHHHHCCCEEEEEC
CGWGGLAKYAAENYGVSVVGITISQQQYELAKTRCAHLPVEIRFQDYRDLNEKFDRIVSL
CCCHHHHHHHHHCCCEEEEEEEECHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHHH
GMFEHVGYKNYRKYMEIVHQCLNDDGLFILHTIGSNESVTKATPWISKYIFPNGMIPSIM
HHHHHCCHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCHHHHHHCCCCCCHHHHH
QIGQASEKLFVMEDWHNFGADYYKTLMAWHENFNKGWDQIKSQYSEKFFRMWNYYLLSCA
HHCCCCCEEEEEECHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GAFDARMLQLWQIVFSKKGIQGGYSAPR
CHHHHHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MNVSTSFIKREFDMDIKKNKAKIFVNYMLQLANININGQTPWDIQIYNDEFYSRLLRDAD
CCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHEEEECCCCCEEEEEECHHHHHHHHHHCC
LGLGESYMDGWWDCQRIDLFISKLINANLESKIKINFKLAFNVFLSKILNLQTQKRSLHV
CCCCCHHHCCCCCHHHHHHHHHHHHCCCCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHHH
GRQHYDRGNDLFQIMLDSNMNYTCGYWRKAENLEQAQLDKLDLTCRKLCLKPGMKLLDIG
HHHHHCCCCCEEEEEECCCCCCEECCCHHHCCCCHHHHHHHHHHHHHHHHHCCCEEEEEC
CGWGGLAKYAAENYGVSVVGITISQQQYELAKTRCAHLPVEIRFQDYRDLNEKFDRIVSL
CCCHHHHHHHHHCCCEEEEEEEECHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHHH
GMFEHVGYKNYRKYMEIVHQCLNDDGLFILHTIGSNESVTKATPWISKYIFPNGMIPSIM
HHHHHCCHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCHHHHHHCCCCCCHHHHH
QIGQASEKLFVMEDWHNFGADYYKTLMAWHENFNKGWDQIKSQYSEKFFRMWNYYLLSCA
HHCCCCCEEEEEECHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GAFDARMLQLWQIVFSKKGIQGGYSAPR
CHHHHHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]