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The map label for this gene is atpA

Identifier: 52841285

GI number: 52841285

Start: 1148725

End: 1149417

Strand: Reverse

Name: atpA

Synonym: lpg1051

Alternate gene names: 52841285

Gene position: 1149417-1148725 (Counterclockwise)

Preceding gene: 52841286

Following gene: 52841284

Centisome position: 33.83

GC content: 41.41

Gene sequence:

>693_bases
GTGGGAGAAGAAGGATTCTTAGCGCATTTTGCCTTTTCAATCGGTGGATTACCCATCACACAAAGCGTCTTAACCACGTG
GTTCATTATGATCTCCTTATTCATCATGGCATGGAGTACCACTTACAAATGCTCTCTCCTACAGCCAAGCACGTACCAAC
TCATTTGGGAGGGTGTTTTAAGCACCATGTACGATGCAATAAAAGAAGTATTGCCCGAGCACGTTGAACTGATATTTCCT
TTTGTAGCCACCTTGTGGATTTTTATCCTTGTTTCCAATTTAATTGGTGTTATTCCGGGATTTTATTCACCAACAGCGGA
TTTATCGGTGACGGCATCCCTTGCGATAATGACTTTTTTATCGGTACACTGGTTTGGAATTCGTGCCGAGGGGTGGCGAG
AGTATTTGAAACATTATATTAAGCCAACTCCTTTTTTATTGCCTTTTCATTTAATCAGCGAAATCTCTCGAACCTTAGCA
TTGGCTGTCCGCTTGTTTGGTAATATCATGAGCTTGCAATTAACCGCCCTGATTGTCCTCATGATTGCCGGATTTTTAGT
TCCTATTCCAATACTCATTTTACATATTATTGAAGCCATCATCCAAGCGTATATTTTTGGCATGCTGGCCTTAATATACA
TTGCTGGGGGCATTCAAGCCCATGAGCTTAAAAGCCAAGGAGAATCGTTATGA

Upstream 100 bases:

>100_bases
AGAAAATAAAAGGGTATTCCATCAGTTGGACCATCAATTTAATCCTCCTTGGGGTGATTATTGGTGCCATTAACGTGTAT
CTTTTAATTAAGGACTAACT

Downstream 100 bases:

>100_bases
ATGACATAAGTTGGTTTAGTTTAGCGTCAACCGTTATTGCCGCAATAGCCATTGCCATAGGAACTATAGGGCCGGCTCTA
GCCATGGGGCGCGCGATTAG

Product: F0F1 ATP synthase subunit A

Products: ADP; phosphate; H+

Alternate protein names: ATP synthase F0 sector subunit a; F-ATPase subunit 6 [H]

Number of amino acids: Translated: 230; Mature: 229

Protein sequence:

>230_residues
MGEEGFLAHFAFSIGGLPITQSVLTTWFIMISLFIMAWSTTYKCSLLQPSTYQLIWEGVLSTMYDAIKEVLPEHVELIFP
FVATLWIFILVSNLIGVIPGFYSPTADLSVTASLAIMTFLSVHWFGIRAEGWREYLKHYIKPTPFLLPFHLISEISRTLA
LAVRLFGNIMSLQLTALIVLMIAGFLVPIPILILHIIEAIIQAYIFGMLALIYIAGGIQAHELKSQGESL

Sequences:

>Translated_230_residues
MGEEGFLAHFAFSIGGLPITQSVLTTWFIMISLFIMAWSTTYKCSLLQPSTYQLIWEGVLSTMYDAIKEVLPEHVELIFP
FVATLWIFILVSNLIGVIPGFYSPTADLSVTASLAIMTFLSVHWFGIRAEGWREYLKHYIKPTPFLLPFHLISEISRTLA
LAVRLFGNIMSLQLTALIVLMIAGFLVPIPILILHIIEAIIQAYIFGMLALIYIAGGIQAHELKSQGESL
>Mature_229_residues
GEEGFLAHFAFSIGGLPITQSVLTTWFIMISLFIMAWSTTYKCSLLQPSTYQLIWEGVLSTMYDAIKEVLPEHVELIFPF
VATLWIFILVSNLIGVIPGFYSPTADLSVTASLAIMTFLSVHWFGIRAEGWREYLKHYIKPTPFLLPFHLISEISRTLAL
AVRLFGNIMSLQLTALIVLMIAGFLVPIPILILHIIEAIIQAYIFGMLALIYIAGGIQAHELKSQGESL

Specific function: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane [H]

COG id: COG0356

COG function: function code C; F0F1-type ATP synthase, subunit a

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase A chain family [H]

Homologues:

Organism=Escherichia coli, GI1790176, Length=214, Percent_Identity=26.1682242990654, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000568
- InterPro:   IPR023011 [H]

Pfam domain/function: PF00119 ATP-synt_A [H]

EC number: 3.6.3.14

Molecular weight: Translated: 25723; Mature: 25592

Theoretical pI: Translated: 6.14; Mature: 6.14

Prosite motif: PS00449 ATPASE_A

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGEEGFLAHFAFSIGGLPITQSVLTTWFIMISLFIMAWSTTYKCSLLQPSTYQLIWEGVL
CCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHH
STMYDAIKEVLPEHVELIFPFVATLWIFILVSNLIGVIPGFYSPTADLSVTASLAIMTFL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHH
SVHWFGIRAEGWREYLKHYIKPTPFLLPFHLISEISRTLALAVRLFGNIMSLQLTALIVL
HHHHHCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MIAGFLVPIPILILHIIEAIIQAYIFGMLALIYIAGGIQAHELKSQGESL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCC
>Mature Secondary Structure 
GEEGFLAHFAFSIGGLPITQSVLTTWFIMISLFIMAWSTTYKCSLLQPSTYQLIWEGVL
CCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHH
STMYDAIKEVLPEHVELIFPFVATLWIFILVSNLIGVIPGFYSPTADLSVTASLAIMTFL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHH
SVHWFGIRAEGWREYLKHYIKPTPFLLPFHLISEISRTLALAVRLFGNIMSLQLTALIVL
HHHHHCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MIAGFLVPIPILILHIIEAIIQAYIFGMLALIYIAGGIQAHELKSQGESL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: Borate; diphosphate; HCO3- [C]

Metal ions: Co2+; Fe2+; Mn2+; Zn2+ [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; H2O; H+

Specific reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out)

General reaction: Phosphorous acid anhydride hydrolysis [C]

Inhibitor: Ca2+; CN-; Efrapeptin; Ethidiumbromide; Guanidines analogs; Oligomycin; Quercetin; Trialkyl tin derivatives; Venturicidin [C]

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA