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The map label for this gene is atpA1

Identifier: 52841282

GI number: 52841282

Start: 1146245

End: 1147717

Strand: Reverse

Name: atpA1

Synonym: lpg1048

Alternate gene names: 52841282

Gene position: 1147717-1146245 (Counterclockwise)

Preceding gene: 52841283

Following gene: 52841281

Centisome position: 33.78

GC content: 43.65

Gene sequence:

>1473_bases
ATGAATTGGTCTAACACCCCTTCTTTTCTTGAGAAGCAACGACAACGCCTTGAGCGCTATCAATTTCAAATCAAGGTATC
CGAACAAGGGCGGGTGGTTTCTGTTGGAGATGGGATTATCTGGATTAAGGGCTTACCAGGGGCTGCCATCGATGAAATTC
TTATTTCAGAGGATGAGTGCTGTATCGCGATGGTGTTCCACCTCACCGAAGAGCTGGTTGGCGCTGTGATGCTGGTACAA
ACCAAAAAATTAAAGGCAGGCACCCCTATTTTTCCTCTGAAACGCGTATTGAGTATTCCTGTAGGTGATAAACTGCTTGG
GCGAGTGATTGATCCTCTAGGCCATCCATTAGACGGCGGTGAGATTCCGCCCCATGAAGAACAAGGATTACTGGATAGGC
TGTCCCCACCTATTCTTCACCGTGACTTTGTGAATCGACCATTGTACACAGGAAATAAGATGCTTGATAATCTAATTCCC
ATTGGAAAAGGACAAAGGGAGTTACTGATTGGGGATAATGGGCTTGGTAAAAGTGCTTTGGCCCTTGACATTGTGATGAA
TCAAAAAGATAAAAAAGTGTATTGTGTCTATGTGTTGATTGGCCAAAAACGTTCCACGGTAAGCTCTACCATTCAATTAT
TAAAAGAAGCCAATGCATTGGACTATACGACTGTTGTAGTAGCCCAAGCGACGGCCTTACCAGGATTACTTTATCTGGCT
CCTTTTGCAGGGTGCGCCATTGCCGAACACTGGATGAAAAAGGGCTTAGATGCCCTGGTGATCTATGATGATTTGAGTGC
TCATGCCAATAGTTATCGTGAACTGTCCCTTTTACTGCGTAGACCTCCTGGACGTGAGGCATTTCCTGCGGACATTTTTT
ATCTGCATTCCCGTTTATTAGAACGCTCCACCTGTCTTTCCCCTGCTCTGGGCGGCGGTAGTATGACGGCGTTGCCTATT
ATCGAAACCAAAGAAGGTGAAATGGCCACTTATATTCCAACGAATCTCATCTCCATCACTGATGGGCAAATCTTTTTTGA
TGAATCCTTATTCTCTTCTGGATTTCTTCCCGCCATTGATATCACCAAATCGGTCTCACGAGTCGGTGGTAAAGCGCAGC
ATCCGCAAATTAAAAAAGAATCCGGTCGAATGAAACTGGATTACCTGCAATTTCTTGATTTGGAACTGTTCACCCGCTTT
GGGGCGAAACTGGATGCCAAAATGCAAAAGCAGATTCAAAAAGGGCGAGTTTTAAGAGAAATTCTAAAACAAGAACGTTT
TTCACCACTACCCATTGAATTTCAACTCGCATGGCTTATTGCTTACAATGAGGGTTTCTTTGACGAATTGAATTTAGAAG
ACATCCCCAAAATGCTCAAAAAAATAGAGGAAGAAATAAAACAAAGCACTTTATCCTTGGGAAGCCCACGAGAACAATGG
AAAAAAGCGATAAAAGAATGGCTAATGGCATAG

Upstream 100 bases:

>100_bases
GAAAATCCAAAGCTTCTCGCGGGATTAACCCTGCAAATGGGCCCCATGTGCTTGCAAGCCAATCTTCGTGATGAATTAAA
ATTCTTTATAGAGACAAAAA

Downstream 100 bases:

>100_bases
AACGGACTCATTATCCACTCCAAAGCAATGAGTATCACTTAATACCCGGATGGTATCATGACGAAACGAACCAAACTCAA
AGAACATGTTCATACTTTAG

Product: F0F1 ATP synthase subunit alpha

Products: NA

Alternate protein names: ATP synthase F1 sector subunit alpha 1; F-ATPase subunit alpha 1

Number of amino acids: Translated: 490; Mature: 490

Protein sequence:

>490_residues
MNWSNTPSFLEKQRQRLERYQFQIKVSEQGRVVSVGDGIIWIKGLPGAAIDEILISEDECCIAMVFHLTEELVGAVMLVQ
TKKLKAGTPIFPLKRVLSIPVGDKLLGRVIDPLGHPLDGGEIPPHEEQGLLDRLSPPILHRDFVNRPLYTGNKMLDNLIP
IGKGQRELLIGDNGLGKSALALDIVMNQKDKKVYCVYVLIGQKRSTVSSTIQLLKEANALDYTTVVVAQATALPGLLYLA
PFAGCAIAEHWMKKGLDALVIYDDLSAHANSYRELSLLLRRPPGREAFPADIFYLHSRLLERSTCLSPALGGGSMTALPI
IETKEGEMATYIPTNLISITDGQIFFDESLFSSGFLPAIDITKSVSRVGGKAQHPQIKKESGRMKLDYLQFLDLELFTRF
GAKLDAKMQKQIQKGRVLREILKQERFSPLPIEFQLAWLIAYNEGFFDELNLEDIPKMLKKIEEEIKQSTLSLGSPREQW
KKAIKEWLMA

Sequences:

>Translated_490_residues
MNWSNTPSFLEKQRQRLERYQFQIKVSEQGRVVSVGDGIIWIKGLPGAAIDEILISEDECCIAMVFHLTEELVGAVMLVQ
TKKLKAGTPIFPLKRVLSIPVGDKLLGRVIDPLGHPLDGGEIPPHEEQGLLDRLSPPILHRDFVNRPLYTGNKMLDNLIP
IGKGQRELLIGDNGLGKSALALDIVMNQKDKKVYCVYVLIGQKRSTVSSTIQLLKEANALDYTTVVVAQATALPGLLYLA
PFAGCAIAEHWMKKGLDALVIYDDLSAHANSYRELSLLLRRPPGREAFPADIFYLHSRLLERSTCLSPALGGGSMTALPI
IETKEGEMATYIPTNLISITDGQIFFDESLFSSGFLPAIDITKSVSRVGGKAQHPQIKKESGRMKLDYLQFLDLELFTRF
GAKLDAKMQKQIQKGRVLREILKQERFSPLPIEFQLAWLIAYNEGFFDELNLEDIPKMLKKIEEEIKQSTLSLGSPREQW
KKAIKEWLMA
>Mature_490_residues
MNWSNTPSFLEKQRQRLERYQFQIKVSEQGRVVSVGDGIIWIKGLPGAAIDEILISEDECCIAMVFHLTEELVGAVMLVQ
TKKLKAGTPIFPLKRVLSIPVGDKLLGRVIDPLGHPLDGGEIPPHEEQGLLDRLSPPILHRDFVNRPLYTGNKMLDNLIP
IGKGQRELLIGDNGLGKSALALDIVMNQKDKKVYCVYVLIGQKRSTVSSTIQLLKEANALDYTTVVVAQATALPGLLYLA
PFAGCAIAEHWMKKGLDALVIYDDLSAHANSYRELSLLLRRPPGREAFPADIFYLHSRLLERSTCLSPALGGGSMTALPI
IETKEGEMATYIPTNLISITDGQIFFDESLFSSGFLPAIDITKSVSRVGGKAQHPQIKKESGRMKLDYLQFLDLELFTRF
GAKLDAKMQKQIQKGRVLREILKQERFSPLPIEFQLAWLIAYNEGFFDELNLEDIPKMLKKIEEEIKQSTLSLGSPREQW
KKAIKEWLMA

Specific function: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit

COG id: COG0056

COG function: function code C; F0F1-type ATP synthase, alpha subunit

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase alpha/beta chains family

Homologues:

Organism=Homo sapiens, GI50345984, Length=467, Percent_Identity=43.8972162740899, Blast_Score=395, Evalue=1e-110,
Organism=Homo sapiens, GI4757810, Length=467, Percent_Identity=43.8972162740899, Blast_Score=395, Evalue=1e-110,
Organism=Homo sapiens, GI32189394, Length=360, Percent_Identity=24.7222222222222, Blast_Score=87, Evalue=4e-17,
Organism=Homo sapiens, GI19913428, Length=409, Percent_Identity=24.4498777506112, Blast_Score=80, Evalue=4e-15,
Organism=Homo sapiens, GI19913426, Length=300, Percent_Identity=25, Blast_Score=77, Evalue=3e-14,
Organism=Escherichia coli, GI1790172, Length=462, Percent_Identity=43.0735930735931, Blast_Score=386, Evalue=1e-108,
Organism=Escherichia coli, GI1788251, Length=272, Percent_Identity=31.9852941176471, Blast_Score=112, Evalue=6e-26,
Organism=Escherichia coli, GI1790170, Length=310, Percent_Identity=24.5161290322581, Blast_Score=98, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI71988063, Length=467, Percent_Identity=43.4689507494647, Blast_Score=403, Evalue=1e-112,
Organism=Caenorhabditis elegans, GI71988080, Length=467, Percent_Identity=43.4689507494647, Blast_Score=402, Evalue=1e-112,
Organism=Caenorhabditis elegans, GI71988074, Length=467, Percent_Identity=40.8993576017131, Blast_Score=363, Evalue=1e-101,
Organism=Caenorhabditis elegans, GI17510931, Length=286, Percent_Identity=25.8741258741259, Blast_Score=85, Evalue=8e-17,
Organism=Caenorhabditis elegans, GI25144756, Length=310, Percent_Identity=23.2258064516129, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17570191, Length=288, Percent_Identity=25.3472222222222, Blast_Score=80, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6319370, Length=449, Percent_Identity=43.8752783964365, Blast_Score=372, Evalue=1e-103,
Organism=Saccharomyces cerevisiae, GI6319603, Length=287, Percent_Identity=26.4808362369338, Blast_Score=91, Evalue=5e-19,
Organism=Saccharomyces cerevisiae, GI6322581, Length=332, Percent_Identity=24.0963855421687, Blast_Score=82, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24658560, Length=454, Percent_Identity=45.5947136563877, Blast_Score=406, Evalue=1e-113,
Organism=Drosophila melanogaster, GI24638766, Length=310, Percent_Identity=24.1935483870968, Blast_Score=86, Evalue=8e-17,
Organism=Drosophila melanogaster, GI28574560, Length=311, Percent_Identity=24.7588424437299, Blast_Score=83, Evalue=4e-16,
Organism=Drosophila melanogaster, GI281361666, Length=289, Percent_Identity=24.9134948096886, Blast_Score=80, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24646341, Length=289, Percent_Identity=24.9134948096886, Blast_Score=80, Evalue=3e-15,
Organism=Drosophila melanogaster, GI17136796, Length=289, Percent_Identity=24.9134948096886, Blast_Score=80, Evalue=3e-15,

Paralogues:

None

Copy number: 9,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): ATPA1_LEGPA (Q5X2Q3)

Other databases:

- EMBL:   CR628336
- RefSeq:   YP_124645.1
- ProteinModelPortal:   Q5X2Q3
- SMR:   Q5X2Q3
- STRING:   Q5X2Q3
- GeneID:   3119402
- GenomeReviews:   CR628336_GR
- KEGG:   lpp:lpp2334
- LegioList:   lpp2334
- eggNOG:   COG0056
- HOGENOM:   HBG565875
- OMA:   HAQTYRE
- ProtClustDB:   PRK13343
- BioCyc:   LPNE297246:LPP2334-MONOMER
- HAMAP:   MF_01346
- InterPro:   IPR020003
- InterPro:   IPR000194
- InterPro:   IPR005294
- InterPro:   IPR017458
- InterPro:   IPR018118
- InterPro:   IPR000793
- PANTHER:   PTHR15184:SF3
- TIGRFAMs:   TIGR00962

Pfam domain/function: PF00006 ATP-synt_ab; PF00306 ATP-synt_ab_C; SSF47917 ATPase_a/b_C; SSF50615 ATPase_a/b_N

EC number: =3.6.3.14

Molecular weight: Translated: 54852; Mature: 54852

Theoretical pI: Translated: 7.91; Mature: 7.91

Prosite motif: PS00152 ATPASE_ALPHA_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNWSNTPSFLEKQRQRLERYQFQIKVSEQGRVVSVGDGIIWIKGLPGAAIDEILISEDEC
CCCCCCHHHHHHHHHHHHHHEEEEEECCCCCEEEECCCEEEEECCCCHHHHHHHCCCCCH
CIAMVFHLTEELVGAVMLVQTKKLKAGTPIFPLKRVLSIPVGDKLLGRVIDPLGHPLDGG
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCHHHHHHHHHHHCCCCCCC
EIPPHEEQGLLDRLSPPILHRDFVNRPLYTGNKMLDNLIPIGKGQRELLIGDNGLGKSAL
CCCCCCCCCHHHHCCCCHHHHHHHCCCCCCCHHHHHHCCCCCCCCCEEEECCCCCCCHHE
ALDIVMNQKDKKVYCVYVLIGQKRSTVSSTIQLLKEANALDYTTVVVAQATALPGLLYLA
EEEEEECCCCCEEEEEEEEECCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCHHHHHH
PFAGCAIAEHWMKKGLDALVIYDDLSAHANSYRELSLLLRRPPGREAFPADIFYLHSRLL
HHHHHHHHHHHHHCCCCEEEEEECHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHH
ERSTCLSPALGGGSMTALPIIETKEGEMATYIPTNLISITDGQIFFDESLFSSGFLPAID
HHHHHCCCCCCCCCEEEEEEEECCCCCEEEECCCCEEEEECCCEEECHHHHCCCCCCHHH
ITKSVSRVGGKAQHPQIKKESGRMKLDYLQFLDLELFTRFGAKLDAKMQKQIQKGRVLRE
HHHHHHHHCCCCCCCCCHHHCCCEEEHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
ILKQERFSPLPIEFQLAWLIAYNEGFFDELNLEDIPKMLKKIEEEIKQSTLSLGSPREQW
HHHHHCCCCCCEEEEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHH
KKAIKEWLMA
HHHHHHHHCC
>Mature Secondary Structure
MNWSNTPSFLEKQRQRLERYQFQIKVSEQGRVVSVGDGIIWIKGLPGAAIDEILISEDEC
CCCCCCHHHHHHHHHHHHHHEEEEEECCCCCEEEECCCEEEEECCCCHHHHHHHCCCCCH
CIAMVFHLTEELVGAVMLVQTKKLKAGTPIFPLKRVLSIPVGDKLLGRVIDPLGHPLDGG
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCHHHHHHHHHHHCCCCCCC
EIPPHEEQGLLDRLSPPILHRDFVNRPLYTGNKMLDNLIPIGKGQRELLIGDNGLGKSAL
CCCCCCCCCHHHHCCCCHHHHHHHCCCCCCCHHHHHHCCCCCCCCCEEEECCCCCCCHHE
ALDIVMNQKDKKVYCVYVLIGQKRSTVSSTIQLLKEANALDYTTVVVAQATALPGLLYLA
EEEEEECCCCCEEEEEEEEECCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCHHHHHH
PFAGCAIAEHWMKKGLDALVIYDDLSAHANSYRELSLLLRRPPGREAFPADIFYLHSRLL
HHHHHHHHHHHHHCCCCEEEEEECHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHH
ERSTCLSPALGGGSMTALPIIETKEGEMATYIPTNLISITDGQIFFDESLFSSGFLPAID
HHHHHCCCCCCCCCEEEEEEEECCCCCEEEECCCCEEEEECCCEEECHHHHCCCCCCHHH
ITKSVSRVGGKAQHPQIKKESGRMKLDYLQFLDLELFTRFGAKLDAKMQKQIQKGRVLRE
HHHHHHHHCCCCCCCCCHHHCCCEEEHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
ILKQERFSPLPIEFQLAWLIAYNEGFFDELNLEDIPKMLKKIEEEIKQSTLSLGSPREQW
HHHHHCCCCCCEEEEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHH
KKAIKEWLMA
HHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA