Click here to switch to the map view.

The map label for this gene is eda

Identifier: 52841174

GI number: 52841174

Start: 1016427

End: 1016990

Strand: Reverse

Name: eda

Synonym: lpg0939

Alternate gene names: 52841174

Gene position: 1016990-1016427 (Counterclockwise)

Preceding gene: 52841175

Following gene: 52841161

Centisome position: 29.93

GC content: 38.3

Gene sequence:

>564_bases
ATGATTATTGAAAAAATCTTAGGTAATCAATCTGTGATCATATCACTGGATATCGATAATTTTTTATTTGACAGACTCGA
TCAAATTGCAAATTCCGATTTGGATTTAGTAGAGATCAACTCGACCGATACCAATTTATTGGTAAAGATTAAAACACAAT
ACCCATCTCTAAAAATTGGAGCCGGCGGCATAATTGATACTCAACAATTAGAGCAATGCTACCAGGCGGGTGTACATTTT
GCCTCTAGCCCCGGCTTTTTAGCTTCTATAGCCCAAACTGCAAGTGTTTATTCGATGTGCTATTTTCCAAGTGTAGCTAC
CATATCAGAAGCTATGGCCGCAGCGAATATTGGATTTAAACAAGTGCGACCCTACCCTGCCAATCTGACATTTTGTAATG
CTCTAAGCAAATATTTACCAGGATTAAATCTGTTCCCAGCTGAAATTGACTGGAATGAAGCTGAGCTTTTCCTAAACTTG
CCAGCTGTAGCAGCAGTAATTATTCATAACCCTGACCATAAGCAACTGAATGGATTAGTTAGGTTGGCACAATCAATTAT
CTGA

Upstream 100 bases:

>100_bases
CATCATCAAACAAATTGTTGTTTTTCTTATCAATACCCTTGCCAACAATCAGCAAGTCTTCTAACATTGAAAGATTATTG
CAGAATTTTCGGAATAAAAC

Downstream 100 bases:

>100_bases
AAATAAATCGATTCTAATTGGTAAGCATTGTTTTCCATTAATAATGCATGACAAGCTTTGGTATAGTATTTTGACTTAGA
AAATGGCTAAGATACTAAAC

Product: 2-dehydro-3-deoxy-phosphogluconate aldolase

Products: Glyceraldehyde 3-phosphate; Pyruvate [C]

Alternate protein names: Eda 2-Dehydro-3-Deoxy-Phosphogluconate Aldolase

Number of amino acids: Translated: 187; Mature: 187

Protein sequence:

>187_residues
MIIEKILGNQSVIISLDIDNFLFDRLDQIANSDLDLVEINSTDTNLLVKIKTQYPSLKIGAGGIIDTQQLEQCYQAGVHF
ASSPGFLASIAQTASVYSMCYFPSVATISEAMAAANIGFKQVRPYPANLTFCNALSKYLPGLNLFPAEIDWNEAELFLNL
PAVAAVIIHNPDHKQLNGLVRLAQSII

Sequences:

>Translated_187_residues
MIIEKILGNQSVIISLDIDNFLFDRLDQIANSDLDLVEINSTDTNLLVKIKTQYPSLKIGAGGIIDTQQLEQCYQAGVHF
ASSPGFLASIAQTASVYSMCYFPSVATISEAMAAANIGFKQVRPYPANLTFCNALSKYLPGLNLFPAEIDWNEAELFLNL
PAVAAVIIHNPDHKQLNGLVRLAQSII
>Mature_187_residues
MIIEKILGNQSVIISLDIDNFLFDRLDQIANSDLDLVEINSTDTNLLVKIKTQYPSLKIGAGGIIDTQQLEQCYQAGVHF
ASSPGFLASIAQTASVYSMCYFPSVATISEAMAAANIGFKQVRPYPANLTFCNALSKYLPGLNLFPAEIDWNEAELFLNL
PAVAAVIIHNPDHKQLNGLVRLAQSII

Specific function: KEY ENZYME IN THE ENTNER-DOUDOROFF PATHWAY. PARTICIPATES IN THE REGULATION OF THE INTRACELLULAR LEVEL OF GLYOXYLATE. [C]

COG id: COG0800

COG function: function code G; 2-keto-3-deoxy-6-phosphogluconate aldolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 4.1.3.16; 4.1.2.14 [C]

Molecular weight: Translated: 20416; Mature: 20416

Theoretical pI: Translated: 4.51; Mature: 4.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIIEKILGNQSVIISLDIDNFLFDRLDQIANSDLDLVEINSTDTNLLVKIKTQYPSLKIG
CCHHHHHCCCEEEEEEECHHHHHHHHHHHHCCCCCEEEECCCCCEEEEEEECCCCCEEEC
AGGIIDTQQLEQCYQAGVHFASSPGFLASIAQTASVYSMCYFPSVATISEAMAAANIGFK
CCCCCCHHHHHHHHHHCCEECCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHH
QVRPYPANLTFCNALSKYLPGLNLFPAEIDWNEAELFLNLPAVAAVIIHNPDHKQLNGLV
HCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCEEEEEECHHHEEEEEECCCHHHHHHHH
RLAQSII
HHHHHCC
>Mature Secondary Structure
MIIEKILGNQSVIISLDIDNFLFDRLDQIANSDLDLVEINSTDTNLLVKIKTQYPSLKIG
CCHHHHHCCCEEEEEEECHHHHHHHHHHHHCCCCCEEEECCCCCEEEEEEECCCCCEEEC
AGGIIDTQQLEQCYQAGVHFASSPGFLASIAQTASVYSMCYFPSVATISEAMAAANIGFK
CCCCCCHHHHHHHHHHCCEECCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHH
QVRPYPANLTFCNALSKYLPGLNLFPAEIDWNEAELFLNLPAVAAVIIHNPDHKQLNGLV
HCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCEEEEEECHHHEEEEEECCCHHHHHHHH
RLAQSII
HHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 2-Dehydro-3-deoxy-D-gluconate 6-phosphate [C]

Specific reaction: 2-Dehydro-3-deoxy-D-gluconate 6-phosphate --> Glyceraldehyde 3-phosphate + Pyruvate [C]

General reaction: Condensation; Elimination [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA