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The map label for this gene is ywbI [H]

Identifier: 39997880

GI number: 39997880

Start: 3066335

End: 3067252

Strand: Direct

Name: ywbI [H]

Synonym: GSU2787

Alternate gene names: 39997880

Gene position: 3066335-3067252 (Clockwise)

Preceding gene: 39997876

Following gene: 39997881

Centisome position: 80.39

GC content: 61.98

Gene sequence:

>918_bases
ATGGAAATCAGACAGTTGCGCTTTTTCATCGAGATCGCCCGGAAACTGAGCTTCACCCGGGCGGCGGAAACGCTCCACAT
AGCACAGCCCGCCCTGAGCACCGCCATCAGGAAGCTGGAGGACGAGCTGGGGCTTACGCTCTTCAACCGCAGCGACCGGA
AGATCGCCCTCACGGCGGAGGGAGAAACATTCCTGCGCCACGCAACGGCAATCCTTGACGACGTGCGGAAGGCGGAGCGG
GAGATGGCCGACATCCGTGGACTAACGGCGGGGGAGGTACGAGTGGGGGTGACTCCGATGCTCAGCACCTACTTTTTCCC
GAAGATCATCGCCGGGTTCAAAAAGCGTCACCCTGCCCTGCAGCTATCGGTGTACGGTGACAGCGCCGCGCGGATTCAGC
GGATGGTCGCGGGCGGAGAGCTCGATATGGGGGTTGTGGCCGGCGGTGCCATCCCGGAGGACCTGGAATACCATCATCTC
CTCCATGAGGAGATCGTGGCCTGCGTTCCGGCCGATCACCCCCTGGCCGGTCGGAAGTCGGTTCCCTTTGCCGAGCTGCT
GCGTGAACCGCTGATCCTCTTCAAGGAGGGATACCATCTGCGGGAACTGATCGACGAAGCCGCAGCCCACGTCGGGGAAG
CCCCCCGGGCGGTGTTCGAGTCGAACCTCTTCTCTCTTATCAGGAACCTGGTCCTGGAGGGAGTCGGGATTTCATTCCTG
CTGCGGATGGTGGTCGCCGACGAGAAGGATCTTGTAGCGCTGCGCTGCGACCCTCCCCTCCACCTGGATCTCTTCATCGC
CTGGAAACGGCAGACAGGGCTCTCGCGGGCAAACCGCGCCTTTGCCGATTACCTCATTGACCAGACCGACGAATACTACC
GGCTGTCGGAGATGTACGGCTCTTTCCCGTTGCCCTAG

Upstream 100 bases:

>100_bases
GCAGAAACGGTCTTTGCAAATGCAGTCACCCCTGTAACCCATACCGATCAGCTATGGTTTAACAGCATTGACCGGCTCAC
ACCCGCACGAAAGGTCACCC

Downstream 100 bases:

>100_bases
CTACCATTCTTGACACCTCCGGATTGCCTGTTATTTTTTGAGCACAAACCACCCTGCCCGCCCGTCCCCTGCCACCGAAA
AACGCACGCTTCCCGACACG

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 305; Mature: 305

Protein sequence:

>305_residues
MEIRQLRFFIEIARKLSFTRAAETLHIAQPALSTAIRKLEDELGLTLFNRSDRKIALTAEGETFLRHATAILDDVRKAER
EMADIRGLTAGEVRVGVTPMLSTYFFPKIIAGFKKRHPALQLSVYGDSAARIQRMVAGGELDMGVVAGGAIPEDLEYHHL
LHEEIVACVPADHPLAGRKSVPFAELLREPLILFKEGYHLRELIDEAAAHVGEAPRAVFESNLFSLIRNLVLEGVGISFL
LRMVVADEKDLVALRCDPPLHLDLFIAWKRQTGLSRANRAFADYLIDQTDEYYRLSEMYGSFPLP

Sequences:

>Translated_305_residues
MEIRQLRFFIEIARKLSFTRAAETLHIAQPALSTAIRKLEDELGLTLFNRSDRKIALTAEGETFLRHATAILDDVRKAER
EMADIRGLTAGEVRVGVTPMLSTYFFPKIIAGFKKRHPALQLSVYGDSAARIQRMVAGGELDMGVVAGGAIPEDLEYHHL
LHEEIVACVPADHPLAGRKSVPFAELLREPLILFKEGYHLRELIDEAAAHVGEAPRAVFESNLFSLIRNLVLEGVGISFL
LRMVVADEKDLVALRCDPPLHLDLFIAWKRQTGLSRANRAFADYLIDQTDEYYRLSEMYGSFPLP
>Mature_305_residues
MEIRQLRFFIEIARKLSFTRAAETLHIAQPALSTAIRKLEDELGLTLFNRSDRKIALTAEGETFLRHATAILDDVRKAER
EMADIRGLTAGEVRVGVTPMLSTYFFPKIIAGFKKRHPALQLSVYGDSAARIQRMVAGGELDMGVVAGGAIPEDLEYHHL
LHEEIVACVPADHPLAGRKSVPFAELLREPLILFKEGYHLRELIDEAAAHVGEAPRAVFESNLFSLIRNLVLEGVGISFL
LRMVVADEKDLVALRCDPPLHLDLFIAWKRQTGLSRANRAFADYLIDQTDEYYRLSEMYGSFPLP

Specific function: Positive Regulatory Protein For The Cyn Operon. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI157672245, Length=291, Percent_Identity=34.020618556701, Blast_Score=157, Evalue=1e-39,
Organism=Escherichia coli, GI1790399, Length=263, Percent_Identity=31.5589353612167, Blast_Score=129, Evalue=3e-31,
Organism=Escherichia coli, GI1787879, Length=317, Percent_Identity=30.5993690851735, Blast_Score=128, Evalue=4e-31,
Organism=Escherichia coli, GI1788887, Length=246, Percent_Identity=32.9268292682927, Blast_Score=127, Evalue=1e-30,
Organism=Escherichia coli, GI1787530, Length=281, Percent_Identity=28.8256227758007, Blast_Score=125, Evalue=5e-30,
Organism=Escherichia coli, GI1788748, Length=290, Percent_Identity=27.2413793103448, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI87081904, Length=260, Percent_Identity=31.1538461538462, Blast_Score=108, Evalue=6e-25,
Organism=Escherichia coli, GI1787601, Length=184, Percent_Identity=31.5217391304348, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI145693105, Length=242, Percent_Identity=28.5123966942149, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1788481, Length=289, Percent_Identity=27.3356401384083, Blast_Score=95, Evalue=6e-21,
Organism=Escherichia coli, GI1788296, Length=289, Percent_Identity=27.3356401384083, Blast_Score=95, Evalue=7e-21,
Organism=Escherichia coli, GI1786401, Length=288, Percent_Identity=27.7777777777778, Blast_Score=90, Evalue=1e-19,
Organism=Escherichia coli, GI2367136, Length=251, Percent_Identity=25.0996015936255, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1788297, Length=242, Percent_Identity=26.4462809917355, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI1789204, Length=250, Percent_Identity=24, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1788706, Length=173, Percent_Identity=31.2138728323699, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1787589, Length=161, Percent_Identity=32.9192546583851, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1787806, Length=245, Percent_Identity=24.4897959183673, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI87082132, Length=263, Percent_Identity=25.0950570342205, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI1790208, Length=200, Percent_Identity=26.5, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI1786508, Length=179, Percent_Identity=30.7262569832402, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1789173, Length=122, Percent_Identity=32.7868852459016, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI48994962, Length=83, Percent_Identity=40.9638554216867, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1787128, Length=295, Percent_Identity=23.728813559322, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1790262, Length=246, Percent_Identity=23.9837398373984, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI1789506, Length=180, Percent_Identity=25, Blast_Score=65, Evalue=7e-12,
Organism=Escherichia coli, GI1789639, Length=122, Percent_Identity=26.2295081967213, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI145693193, Length=153, Percent_Identity=27.4509803921569, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1786713, Length=308, Percent_Identity=25, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34221; Mature: 34221

Theoretical pI: Translated: 6.36; Mature: 6.36

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEIRQLRFFIEIARKLSFTRAAETLHIAQPALSTAIRKLEDELGLTLFNRSDRKIALTAE
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEECCCCCEEEEEEC
GETFLRHATAILDDVRKAEREMADIRGLTAGEVRVGVTPMLSTYFFPKIIAGFKKRHPAL
CHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCHHHHHHHHHHHHHHHHHHCCCEE
QLSVYGDSAARIQRMVAGGELDMGVVAGGAIPEDLEYHHLLHEEIVACVPADHPLAGRKS
EEEEECCHHHHHHHHHCCCCCCCCEEECCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCC
VPFAELLREPLILFKEGYHLRELIDEAAAHVGEAPRAVFESNLFSLIRNLVLEGVGISFL
CCHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCHHHH
LRMVVADEKDLVALRCDPPLHLDLFIAWKRQTGLSRANRAFADYLIDQTDEYYRLSEMYG
HHHHHCCCCCEEEEECCCCCEEEEEEEEEHHHCHHHHHHHHHHHHHCCCHHHHHHHHHCC
SFPLP
CCCCC
>Mature Secondary Structure
MEIRQLRFFIEIARKLSFTRAAETLHIAQPALSTAIRKLEDELGLTLFNRSDRKIALTAE
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEECCCCCEEEEEEC
GETFLRHATAILDDVRKAEREMADIRGLTAGEVRVGVTPMLSTYFFPKIIAGFKKRHPAL
CHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCHHHHHHHHHHHHHHHHHHCCCEE
QLSVYGDSAARIQRMVAGGELDMGVVAGGAIPEDLEYHHLLHEEIVACVPADHPLAGRKS
EEEEECCHHHHHHHHHCCCCCCCCEEECCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCC
VPFAELLREPLILFKEGYHLRELIDEAAAHVGEAPRAVFESNLFSLIRNLVLEGVGISFL
CCHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCHHHH
LRMVVADEKDLVALRCDPPLHLDLFIAWKRQTGLSRANRAFADYLIDQTDEYYRLSEMYG
HHHHHCCCCCEEEEECCCCCEEEEEEEEEHHHCHHHHHHHHHHHHHCCCHHHHHHHHHCC
SFPLP
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7934828; 9384377 [H]