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The map label for this gene is ynfJ [C]

Identifier: 39997459

GI number: 39997459

Start: 2589290

End: 2591134

Strand: Direct

Name: ynfJ [C]

Synonym: GSU2363

Alternate gene names: 39997459

Gene position: 2589290-2591134 (Clockwise)

Preceding gene: 39997457

Following gene: 39997465

Centisome position: 67.89

GC content: 63.2

Gene sequence:

>1845_bases
ATGAAGCTTGAGTTTCCCGGAAAATCTGCACGGTGGACCACACCGCTGATCCTCATCAGGGATCTTCATCTGCTGCGCCG
GTTCGTCCGAATGCGGCGGGCGGTTTTTTCTCTCCTCTCCCGGTTTCGGATCAGCGAAAATACGCTCATGGCGATTCTCG
CCGTGGGGATCGGCCTGTTGGCGGGACTGTGCAACTACGCCTTCCGCTCGTGCATCGACCTGTTCCGGTGGCTCATCATC
GACAGCGGCGGGCAGTTGACCGGCTATTCGCCCTATGCCTGGAACGCGAGCCGTCTCTGGGCTATCGCCTTTCCCATCAC
CGGCGCCATCGTCATGTTCCCCCTGTTCATCAAATTCAGGGAAGACATGGCCTTCGGCTTCCCCCGGTTTCTGGAAACGG
TCAATCTGCGGGGCGGGCGACTGCCGCTCAGGCTCATGTTCACCAGGGGGATTTCGTCGGCGCTCACCATCGGCTCCGGC
GGCTCCGCCGGCCAGGAAGGCCCCATCGCCCAGATCGGCGGCACGGCCGGCTCCGTGGTGGGGCACCTGCTCGGCATGTC
GGGAGAGCGTCTCAAGGTCCTCATCGGCTGCGGGGTCTCCGGCGGAGTTGCCGCCACCTTCAATGCCCCCCTTGCCGGGG
TGTTTTTCGCCCATGAAATCGTCCTTCTCTCCTCCTTCGAGCTCTCTTCCTTCACGAGCATCGTCATCTCGTCCGGCATG
GCCACCGTTGTCTCCCGGGCCATGTATGGCGACATCCCCGCCTTCGACGTGCCCGCCTACCAGCTCGTTCACCCCCTCGA
ACTTGCCTTCTACGCCCTGCTCGGGGTGGTGTGCGGCTGCCTCGCGGCCCTCTTCATAACAGGCTACGGGAAAACCAGGG
ACATGTTCTCGCGCCTCCCTATCAATCCACTGTGGAAACCTCTTCTGGGCGGGTTTCTCGTCGGCTGCGTCGCGGTTCTT
CTGCCCCAGGTCCAGGGCAACGGTTACGAGTTCATCGAAAAAGCCGTTTCCAACGACGTGGGGTGGCTCCTTGTCACGCT
CCTTATCGTCGGCAAGATGGTCGCCACCTGCGTAACGGTCGGCTCGGGGCTGCCGGGCGGGACCTTTGCGCCGTCCCTGT
TCATCGGTTCGGTCACCGGCATGAGTTTCGGCTTCCTGGCGAACAGCCTCTTCCCGTATCAGACGGCAACGCCGGGCGCC
TATGCCCTGGTGGGGATGGGCGCGTTCCTCGCATCGGTCACCCACGCGCCCATGACCGGCATCTTCCTGCTCTTCGAGAT
GACCGGTTCCTACAAGGTCATTGTGCCGATCATGCTCGCCTGCGCCATCGGCACCGCCGTGGCCCGCCACTTCCACAAAG
ACGGCATCGATACTGCCGACCTGGCCGCCCAGGGGATCGACCTGCGGGCCGGGCGAGAACAGAGGGTCCTGGAGCGAATC
CGGGTCAAGGGGGTCATGATGCGCGACCCGGAGATACTCCCGGAAACCATGACCATCCGCCAGTTCCTGGCCCGCAGCCA
TTCGCCGCGCCAGACCACCTTCCCCGTCGTCACTGGCGGGGGAGAGCTTTCCGGGGTCGTGGTCATCCATGACTTCCTGG
GGATCGCGTTCGAGCAGGAGCTTCTCGACCAGGTCACCTTGGGCGAAATGGCCGCCGTGGACATTTTGACCGTCACCAGC
GAAGACACTCTGGCGAAAGCACTCCAGATCTTCGAGCGCACGCCCCTGGACGAGCTTCCCGTTGTGGAGCCCGGCGGACA
AAGGCGGGTGGTCGGCATTCTCACCCGCCACGCCATTACCGGTGCGTACAACAGGGCAATGGTGACACAATCGCTCAAGG
AGTGA

Upstream 100 bases:

>100_bases
AACCGCGGCAGTATATAATTTGCATTCAAACAATCGGGATGCGACGGGGCGGCCCGCATTCCGAAAACCGGGCTTTCCCG
CCCAGGAGCCGCATCCTGCC

Downstream 100 bases:

>100_bases
ACACGGACCAATCCACAGACATTATCAATGTCTCAACTAATTGTCTCGTTTAGCTGGTACAGGGGGCAATGGTGAGGCAT
TGTGGCTGCCGGCATGGCGC

Product: chloride channel family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 614; Mature: 614

Protein sequence:

>614_residues
MKLEFPGKSARWTTPLILIRDLHLLRRFVRMRRAVFSLLSRFRISENTLMAILAVGIGLLAGLCNYAFRSCIDLFRWLII
DSGGQLTGYSPYAWNASRLWAIAFPITGAIVMFPLFIKFREDMAFGFPRFLETVNLRGGRLPLRLMFTRGISSALTIGSG
GSAGQEGPIAQIGGTAGSVVGHLLGMSGERLKVLIGCGVSGGVAATFNAPLAGVFFAHEIVLLSSFELSSFTSIVISSGM
ATVVSRAMYGDIPAFDVPAYQLVHPLELAFYALLGVVCGCLAALFITGYGKTRDMFSRLPINPLWKPLLGGFLVGCVAVL
LPQVQGNGYEFIEKAVSNDVGWLLVTLLIVGKMVATCVTVGSGLPGGTFAPSLFIGSVTGMSFGFLANSLFPYQTATPGA
YALVGMGAFLASVTHAPMTGIFLLFEMTGSYKVIVPIMLACAIGTAVARHFHKDGIDTADLAAQGIDLRAGREQRVLERI
RVKGVMMRDPEILPETMTIRQFLARSHSPRQTTFPVVTGGGELSGVVVIHDFLGIAFEQELLDQVTLGEMAAVDILTVTS
EDTLAKALQIFERTPLDELPVVEPGGQRRVVGILTRHAITGAYNRAMVTQSLKE

Sequences:

>Translated_614_residues
MKLEFPGKSARWTTPLILIRDLHLLRRFVRMRRAVFSLLSRFRISENTLMAILAVGIGLLAGLCNYAFRSCIDLFRWLII
DSGGQLTGYSPYAWNASRLWAIAFPITGAIVMFPLFIKFREDMAFGFPRFLETVNLRGGRLPLRLMFTRGISSALTIGSG
GSAGQEGPIAQIGGTAGSVVGHLLGMSGERLKVLIGCGVSGGVAATFNAPLAGVFFAHEIVLLSSFELSSFTSIVISSGM
ATVVSRAMYGDIPAFDVPAYQLVHPLELAFYALLGVVCGCLAALFITGYGKTRDMFSRLPINPLWKPLLGGFLVGCVAVL
LPQVQGNGYEFIEKAVSNDVGWLLVTLLIVGKMVATCVTVGSGLPGGTFAPSLFIGSVTGMSFGFLANSLFPYQTATPGA
YALVGMGAFLASVTHAPMTGIFLLFEMTGSYKVIVPIMLACAIGTAVARHFHKDGIDTADLAAQGIDLRAGREQRVLERI
RVKGVMMRDPEILPETMTIRQFLARSHSPRQTTFPVVTGGGELSGVVVIHDFLGIAFEQELLDQVTLGEMAAVDILTVTS
EDTLAKALQIFERTPLDELPVVEPGGQRRVVGILTRHAITGAYNRAMVTQSLKE
>Mature_614_residues
MKLEFPGKSARWTTPLILIRDLHLLRRFVRMRRAVFSLLSRFRISENTLMAILAVGIGLLAGLCNYAFRSCIDLFRWLII
DSGGQLTGYSPYAWNASRLWAIAFPITGAIVMFPLFIKFREDMAFGFPRFLETVNLRGGRLPLRLMFTRGISSALTIGSG
GSAGQEGPIAQIGGTAGSVVGHLLGMSGERLKVLIGCGVSGGVAATFNAPLAGVFFAHEIVLLSSFELSSFTSIVISSGM
ATVVSRAMYGDIPAFDVPAYQLVHPLELAFYALLGVVCGCLAALFITGYGKTRDMFSRLPINPLWKPLLGGFLVGCVAVL
LPQVQGNGYEFIEKAVSNDVGWLLVTLLIVGKMVATCVTVGSGLPGGTFAPSLFIGSVTGMSFGFLANSLFPYQTATPGA
YALVGMGAFLASVTHAPMTGIFLLFEMTGSYKVIVPIMLACAIGTAVARHFHKDGIDTADLAAQGIDLRAGREQRVLERI
RVKGVMMRDPEILPETMTIRQFLARSHSPRQTTFPVVTGGGELSGVVVIHDFLGIAFEQELLDQVTLGEMAAVDILTVTS
EDTLAKALQIFERTPLDELPVVEPGGQRRVVGILTRHAITGAYNRAMVTQSLKE

Specific function: Unknown

COG id: COG0038

COG function: function code P; Chloride channel protein EriC

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the chloride channel (TC 2.A.49) family. ClcB subfamily [H]

Homologues:

Organism=Homo sapiens, GI55770838, Length=554, Percent_Identity=22.9241877256318, Blast_Score=82, Evalue=2e-15,
Organism=Homo sapiens, GI4557473, Length=453, Percent_Identity=24.5033112582781, Blast_Score=82, Evalue=2e-15,
Organism=Homo sapiens, GI189217923, Length=453, Percent_Identity=24.5033112582781, Blast_Score=81, Evalue=3e-15,
Organism=Homo sapiens, GI189217921, Length=453, Percent_Identity=24.5033112582781, Blast_Score=81, Evalue=3e-15,
Organism=Homo sapiens, GI55770840, Length=438, Percent_Identity=23.5159817351598, Blast_Score=81, Evalue=3e-15,
Organism=Homo sapiens, GI153252026, Length=397, Percent_Identity=25.4408060453401, Blast_Score=81, Evalue=4e-15,
Organism=Escherichia coli, GI87081943, Length=411, Percent_Identity=28.9537712895377, Blast_Score=135, Evalue=8e-33,
Organism=Escherichia coli, GI1786350, Length=417, Percent_Identity=29.7362110311751, Blast_Score=125, Evalue=7e-30,
Organism=Caenorhabditis elegans, GI17532615, Length=505, Percent_Identity=22.3762376237624, Blast_Score=89, Evalue=6e-18,
Organism=Drosophila melanogaster, GI24665008, Length=542, Percent_Identity=21.7712177121771, Blast_Score=82, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014743
- InterPro:   IPR001807 [H]

Pfam domain/function: PF00654 Voltage_CLC [H]

EC number: NA

Molecular weight: Translated: 66029; Mature: 66029

Theoretical pI: Translated: 8.86; Mature: 8.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLEFPGKSARWTTPLILIRDLHLLRRFVRMRRAVFSLLSRFRISENTLMAILAVGIGLL
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
AGLCNYAFRSCIDLFRWLIIDSGGQLTGYSPYAWNASRLWAIAFPITGAIVMFPLFIKFR
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEECHHHHHHHHHHHHHHHH
EDMAFGFPRFLETVNLRGGRLPLRLMFTRGISSALTIGSGGSAGQEGPIAQIGGTAGSVV
HHHHCCCHHHHHHHCCCCCCCCEEEEEHHCCCHHEEECCCCCCCCCCCCHHCCCCHHHHH
GHLLGMSGERLKVLIGCGVSGGVAATFNAPLAGVFFAHEIVLLSSFELSSFTSIVISSGM
HHHHCCCCCCEEEEEECCCCCCEEEEECCCHHHHHHHHHHHHHCCCCHHHHHHHHHHCCH
ATVVSRAMYGDIPAFDVPAYQLVHPLELAFYALLGVVCGCLAALFITGYGKTRDMFSRLP
HHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCC
INPLWKPLLGGFLVGCVAVLLPQVQGNGYEFIEKAVSNDVGWLLVTLLIVGKMVATCVTV
CCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
GSGLPGGTFAPSLFIGSVTGMSFGFLANSLFPYQTATPGAYALVGMGAFLASVTHAPMTG
CCCCCCCCCCCHHHHHHHHCCHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHH
IFLLFEMTGSYKVIVPIMLACAIGTAVARHFHKDGIDTADLAAQGIDLRAGREQRVLERI
HEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCCHHHHHHHH
RVKGVMMRDPEILPETMTIRQFLARSHSPRQTTFPVVTGGGELSGVVVIHDFLGIAFEQE
HHCCEEECCCCCCCHHHHHHHHHHCCCCCCCCCCCEEECCCCCCEEEEEHHHHHHHHHHH
LLDQVTLGEMAAVDILTVTSEDTLAKALQIFERTPLDELPVVEPGGQRRVVGILTRHAIT
HHHHHHHCHHHHEEEEEECCHHHHHHHHHHHHHCCCCCCCCCCCCCCEEHHHHHHHHHHH
GAYNRAMVTQSLKE
HHHHHHHHHHHHCC
>Mature Secondary Structure
MKLEFPGKSARWTTPLILIRDLHLLRRFVRMRRAVFSLLSRFRISENTLMAILAVGIGLL
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
AGLCNYAFRSCIDLFRWLIIDSGGQLTGYSPYAWNASRLWAIAFPITGAIVMFPLFIKFR
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEECHHHHHHHHHHHHHHHH
EDMAFGFPRFLETVNLRGGRLPLRLMFTRGISSALTIGSGGSAGQEGPIAQIGGTAGSVV
HHHHCCCHHHHHHHCCCCCCCCEEEEEHHCCCHHEEECCCCCCCCCCCCHHCCCCHHHHH
GHLLGMSGERLKVLIGCGVSGGVAATFNAPLAGVFFAHEIVLLSSFELSSFTSIVISSGM
HHHHCCCCCCEEEEEECCCCCCEEEEECCCHHHHHHHHHHHHHCCCCHHHHHHHHHHCCH
ATVVSRAMYGDIPAFDVPAYQLVHPLELAFYALLGVVCGCLAALFITGYGKTRDMFSRLP
HHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCC
INPLWKPLLGGFLVGCVAVLLPQVQGNGYEFIEKAVSNDVGWLLVTLLIVGKMVATCVTV
CCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
GSGLPGGTFAPSLFIGSVTGMSFGFLANSLFPYQTATPGAYALVGMGAFLASVTHAPMTG
CCCCCCCCCCCHHHHHHHHCCHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHH
IFLLFEMTGSYKVIVPIMLACAIGTAVARHFHKDGIDTADLAAQGIDLRAGREQRVLERI
HEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCCHHHHHHHH
RVKGVMMRDPEILPETMTIRQFLARSHSPRQTTFPVVTGGGELSGVVVIHDFLGIAFEQE
HHCCEEECCCCCCCHHHHHHHHHHCCCCCCCCCCCEEECCCCCCEEEEEHHHHHHHHHHH
LLDQVTLGEMAAVDILTVTSEDTLAKALQIFERTPLDELPVVEPGGQRRVVGILTRHAIT
HHHHHHHCHHHHEEEEEECCHHHHHHHHHHHHHCCCCCCCCCCCCCCEEHHHHHHHHHHH
GAYNRAMVTQSLKE
HHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]