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The map label for this gene is aroF [H]

Identifier: 39997389

GI number: 39997389

Start: 2509036

End: 2510103

Strand: Direct

Name: aroF [H]

Synonym: GSU2291

Alternate gene names: 39997389

Gene position: 2509036-2510103 (Clockwise)

Preceding gene: 39997388

Following gene: 39997391

Centisome position: 65.78

GC content: 59.83

Gene sequence:

>1068_bases
ATGATTCGCACGAGCAACCTGAAGATCAAAAGTATTACCCCCATCATTGCACCGGGGGAATTACGCCAGGTGTTTCCCCA
GTCGGAGGAGGCGGCCGAGTTCGTCAACTCCAGCCGCGCCCATATCAAGAATATCCTCAAGGGCAAGGATCCGCGCCTGA
TGGTGGTGGTGGGCCCCTGTTCCATTCACGATCCGAAATCGGCTCTGGAGTATGCGGGGCGGCTGGCACGCCTGGCGGCC
GAACTGTCGGATCAGCTATTCATCGTGATGCGGGTCTACTTCGAAAAGCCCCGCACTACCGTAGGCTGGAAGGGACTCAT
CAATGACCCCGACATGAACGGCACCCATCAGATATCCAAGGGGCTCGGCATCGCCCGGCGGCTGCTGTCCGAAATAACGG
AAATGCTCCTGCCGGTGGCAACCGAAATGCTTGACCCCATCACGCCCGACTACCTCGCGGATTGCATCTCCTGGGGAGCC
ATCGGCGCTCGTACCACCGAGAGCCAGACCCACCGCGAGATGGCCAGCGGCCTCTCGTTCCCCGTGGGATTCAAGAACGG
CACCGACGGCAATCTCCAGATAGCCATCGACGCCATGAATGCGGCACTCCATTCCCACAGCTTTCTCGGCGTCAACCGGG
AGGGGCGCACCTCCATCATTCAGACCACCGGCAACCCCGATGTCCACATCGTCCTGCGGGGAGGCAAAAAACCGAACTAT
TTCCCCGAAGACATCAGAAAGACCGAAGAGATGCTGGAAAAGGGGGGGCTCTTCCCCACCATCATGGTCGACTGCAGCCA
CGGCAACTCGGAAAAACGCCACGAGAAGCAGCCCGACGTACTCTCTTCCGTCGTGGACCAGATTGCGGCCGGCAACCGCT
CCATCTCCGGCGTCATGATCGAGAGTTTTCTGGAAGAAGGGAACCAGTCGATCCCCAGAGATCTCTCAACCCTCAAGTAC
GGCGTATCCATCACCGACAAGTGCATTGACTGGAAGACCACCGAAACCATCCTGCGCTCGGCCCACGACCGCCTCAAGGC
CGCGGGAGGCAGGCCCCTGCACGGGTAA

Upstream 100 bases:

>100_bases
GGATGACTCGTAGTTCTGGCAAAAACCGGAAAAACGTGCTATTGCTACCCCAACTCGACCATTTCATCGTATTTTCATAT
AGTTCAAGGAGACTAAACCC

Downstream 100 bases:

>100_bases
GCCCACGGTCAGGCAAAGGTAACGCGGGGCAGTTCCAGGGCTTCGGCCAGGGCATGGTGAGCGATGCCGCCCCGCCAGGT
ATTGAGGGCTCCCCCCAGGG

Product: phospho-2-dehydro-3-deoxyheptonate aldolase

Products: NA

Alternate protein names: 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase; DAHP synthase; Phospho-2-keto-3-deoxyheptonate aldolase [H]

Number of amino acids: Translated: 355; Mature: 355

Protein sequence:

>355_residues
MIRTSNLKIKSITPIIAPGELRQVFPQSEEAAEFVNSSRAHIKNILKGKDPRLMVVVGPCSIHDPKSALEYAGRLARLAA
ELSDQLFIVMRVYFEKPRTTVGWKGLINDPDMNGTHQISKGLGIARRLLSEITEMLLPVATEMLDPITPDYLADCISWGA
IGARTTESQTHREMASGLSFPVGFKNGTDGNLQIAIDAMNAALHSHSFLGVNREGRTSIIQTTGNPDVHIVLRGGKKPNY
FPEDIRKTEEMLEKGGLFPTIMVDCSHGNSEKRHEKQPDVLSSVVDQIAAGNRSISGVMIESFLEEGNQSIPRDLSTLKY
GVSITDKCIDWKTTETILRSAHDRLKAAGGRPLHG

Sequences:

>Translated_355_residues
MIRTSNLKIKSITPIIAPGELRQVFPQSEEAAEFVNSSRAHIKNILKGKDPRLMVVVGPCSIHDPKSALEYAGRLARLAA
ELSDQLFIVMRVYFEKPRTTVGWKGLINDPDMNGTHQISKGLGIARRLLSEITEMLLPVATEMLDPITPDYLADCISWGA
IGARTTESQTHREMASGLSFPVGFKNGTDGNLQIAIDAMNAALHSHSFLGVNREGRTSIIQTTGNPDVHIVLRGGKKPNY
FPEDIRKTEEMLEKGGLFPTIMVDCSHGNSEKRHEKQPDVLSSVVDQIAAGNRSISGVMIESFLEEGNQSIPRDLSTLKY
GVSITDKCIDWKTTETILRSAHDRLKAAGGRPLHG
>Mature_355_residues
MIRTSNLKIKSITPIIAPGELRQVFPQSEEAAEFVNSSRAHIKNILKGKDPRLMVVVGPCSIHDPKSALEYAGRLARLAA
ELSDQLFIVMRVYFEKPRTTVGWKGLINDPDMNGTHQISKGLGIARRLLSEITEMLLPVATEMLDPITPDYLADCISWGA
IGARTTESQTHREMASGLSFPVGFKNGTDGNLQIAIDAMNAALHSHSFLGVNREGRTSIIQTTGNPDVHIVLRGGKKPNY
FPEDIRKTEEMLEKGGLFPTIMVDCSHGNSEKRHEKQPDVLSSVVDQIAAGNRSISGVMIESFLEEGNQSIPRDLSTLKY
GVSITDKCIDWKTTETILRSAHDRLKAAGGRPLHG

Specific function: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) [H]

COG id: COG0722

COG function: function code E; 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I DAHP synthase family [H]

Homologues:

Organism=Escherichia coli, GI1788953, Length=341, Percent_Identity=58.3577712609971, Blast_Score=426, Evalue=1e-120,
Organism=Escherichia coli, GI1786969, Length=348, Percent_Identity=56.3218390804598, Blast_Score=390, Evalue=1e-110,
Organism=Escherichia coli, GI1787996, Length=338, Percent_Identity=51.4792899408284, Blast_Score=357, Evalue=1e-100,
Organism=Saccharomyces cerevisiae, GI6320240, Length=343, Percent_Identity=53.6443148688047, Blast_Score=377, Evalue=1e-105,
Organism=Saccharomyces cerevisiae, GI6319726, Length=336, Percent_Identity=52.9761904761905, Blast_Score=352, Evalue=4e-98,

Paralogues:

None

Copy number: 2,200 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR006218
- InterPro:   IPR006219 [H]

Pfam domain/function: PF00793 DAHP_synth_1 [H]

EC number: =2.5.1.54 [H]

Molecular weight: Translated: 38975; Mature: 38975

Theoretical pI: Translated: 7.69; Mature: 7.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRTSNLKIKSITPIIAPGELRQVFPQSEEAAEFVNSSRAHIKNILKGKDPRLMVVVGPC
CCCCCCEEEECCCCEECCCHHHHHCCCCHHHHHHHHCCHHHHHHHHCCCCCEEEEEECCC
SIHDPKSALEYAGRLARLAAELSDQLFIVMRVYFEKPRTTVGWKGLINDPDMNGTHQISK
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHH
GLGIARRLLSEITEMLLPVATEMLDPITPDYLADCISWGAIGARTTESQTHREMASGLSF
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCC
PVGFKNGTDGNLQIAIDAMNAALHSHSFLGVNREGRTSIIQTTGNPDVHIVLRGGKKPNY
CCCCCCCCCCCEEEEEEHHHHHHHHCCEECCCCCCCCEEEEECCCCCEEEEEECCCCCCC
FPEDIRKTEEMLEKGGLFPTIMVDCSHGNSEKRHEKQPDVLSSVVDQIAAGNRSISGVMI
CHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHCCCHHHHHHHHHHHHCCCCCCHHHHH
ESFLEEGNQSIPRDLSTLKYGVSITDKCIDWKTTETILRSAHDRLKAAGGRPLHG
HHHHHHCCCCCCHHHHHHHHCCCCHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MIRTSNLKIKSITPIIAPGELRQVFPQSEEAAEFVNSSRAHIKNILKGKDPRLMVVVGPC
CCCCCCEEEECCCCEECCCHHHHHCCCCHHHHHHHHCCHHHHHHHHCCCCCEEEEEECCC
SIHDPKSALEYAGRLARLAAELSDQLFIVMRVYFEKPRTTVGWKGLINDPDMNGTHQISK
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHH
GLGIARRLLSEITEMLLPVATEMLDPITPDYLADCISWGAIGARTTESQTHREMASGLSF
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCC
PVGFKNGTDGNLQIAIDAMNAALHSHSFLGVNREGRTSIIQTTGNPDVHIVLRGGKKPNY
CCCCCCCCCCCEEEEEEHHHHHHHHCCEECCCCCCCCEEEEECCCCCEEEEEECCCCCCC
FPEDIRKTEEMLEKGGLFPTIMVDCSHGNSEKRHEKQPDVLSSVVDQIAAGNRSISGVMI
CHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHCCCHHHHHHHHHHHHCCCCCCHHHHH
ESFLEEGNQSIPRDLSTLKYGVSITDKCIDWKTTETILRSAHDRLKAAGGRPLHG
HHHHHHCCCCCCHHHHHHHHCCCCHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 6146618; 6396419; 9205837; 9278503; 1977738; 6104668; 2857723; 9056491 [H]