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The map label for this gene is ppiD [H]

Identifier: 39997188

GI number: 39997188

Start: 2296177

End: 2297760

Strand: Direct

Name: ppiD [H]

Synonym: GSU2090

Alternate gene names: 39997188

Gene position: 2296177-2297760 (Clockwise)

Preceding gene: 39997175

Following gene: 39997189

Centisome position: 60.2

GC content: 60.92

Gene sequence:

>1584_bases
ATGCTCGGCATCATGAGGAAGTACAAGCAGTCCCCCGTCATCAAGGTGGTCTTCGGCGTCATCGTTCTCTCCTTCATCGG
AACCATCTTCCTGGTCTGGGGCAAGGGAGAAGGCAAGCTGACTCCTTCCAGCTACGCCGTCAAGGTCGACAGGACCAAAA
TCAGCTACGAGGAATTTCAGCGGACCTACTACCGGCTGCGCGACATTTATGTCCAGCTCTACGGTCCCGCCCTCACCCCC
GACCTGGAAAAACAGCTCAACGTCAAGAAGCAGGCCCTCGACACCCTCGTCGAAGGTGCGCTCGTTCGCAACGCCGCCCG
GGATATGGGAATCAAGGTCAGCAAGGATGATGTTCAGCAGGCCATCGCCGCCATGCCCTCGTTCCAGGTGAACGGAGCCT
TCAGCTTCAACCAGTACGTACAGGTCCTCAAAGCCAACAGGATTGCGCCCAAGGAGTTCGAAGAGGGGCAGAAGGATGAG
CTGATGATCAAGAAGGCCCAGGACCAGATCAAATCCCGGGCCACGGTGAGCGACGACGAGGCGCGCGAGCTTTTCCGCAA
GCGCAACGACCGGCTCGCGATTTCCTATGTATCCTACTCCCCCGACGACGTGAAGGCGGAGATCAAGCTCACCGACCAGG
AGCTTACCGACTTTCTCGCCAAGAACCAGAACGACTTCAAGACCCCCGAGAAGATCAGCATCACCTACGTGATGGTCGAT
CCCCTGAAGGTGGGTGGCCTTGAGGTGAGTGAGGCCGATATCCAGGCCTGGTACCAGAAGAACATCGACCGCTACCAGGG
ACCTGCAGGCATCCTTCCGCTGGCCGAGGTCAAGGAGAAGGTCCGGGAGGACGCCCGGCGCTTCAAGGCCGGTCAGCACG
CTTACGAACTGGCCGCCGCCGCTATCAACAAGAACAAGGCAACCGGCGACATCGGCGCCGTGGCCCGGGCCCTGGGCGCC
AAGACGGAAGAGACCGCCCTGTTCACGGCCCAGCAGCCCGCACCCGCCCTGGCCGGCGAAACAGAGCTGATCCGCCGGGC
CTTCATCCTCAAGGAGGGCGAACTGGGTGGCCCTGTGGAAACGAAAAAGGGAATCTACCTGATCAAGATCAAGGAGCGCA
AACCCGCCGAAGTGCCGCCGCTGGCCCAGATTCGCGCCCAGGTCGAAGAGAAGGCCAAGACAGCGAAGGCAGTGGATCTG
GCGAAGAAGAAAGCCGAAGAGGCCCAGGCAAAGCTGGCCAAAGGCGATTCGACCGGCCTCACGCTCCGGGATTCCGGCCC
CTTCGCCTTCGACGCCAAGGGGAACATCCCCACGGTGGGCGCCTCGCCGGAGCTCATGGAAGCAGCCTTCAAACTCACCA
CCGCGGCGCCGGCACCCAAGGAGCCGATCCGGGTAGGCGCCCGCTGGATTGCCTTCCGCCTCAAGGAACGCACCGAGCTG
AACGCCGCCAACTTTGCGGCGCAAAAGGAAAAGATCAAGCAGGAGATCCTGCCGCGCAAGCAGGACGACGAATATCGCAA
ATGGATCGAAGAGCTTCGGAGCAAGGCGAAGATCGAGATCAACCCCGCCCTCAAGGACATTTGA

Upstream 100 bases:

>100_bases
GTGTAATCATGTTGCGTTCCCATAGGTACTTATAGTAGTATTCGGACCCGTCGTTTCCACGGCGCATCCGAATCCATCCG
GCACAAAGGAGTCCCCGCCA

Downstream 100 bases:

>100_bases
CCATTAACAAGAGGAGATTCAAGCCATGGCAGAACTGGTGCTCAAGACCGATTTCCCCGACCTGAAACTTGCCGGCCGCG
GCAAGGTACGCGACATTTAC

Product: hypothetical protein

Products: NA

Alternate protein names: PPIase D; Rotamase D [H]

Number of amino acids: Translated: 527; Mature: 527

Protein sequence:

>527_residues
MLGIMRKYKQSPVIKVVFGVIVLSFIGTIFLVWGKGEGKLTPSSYAVKVDRTKISYEEFQRTYYRLRDIYVQLYGPALTP
DLEKQLNVKKQALDTLVEGALVRNAARDMGIKVSKDDVQQAIAAMPSFQVNGAFSFNQYVQVLKANRIAPKEFEEGQKDE
LMIKKAQDQIKSRATVSDDEARELFRKRNDRLAISYVSYSPDDVKAEIKLTDQELTDFLAKNQNDFKTPEKISITYVMVD
PLKVGGLEVSEADIQAWYQKNIDRYQGPAGILPLAEVKEKVREDARRFKAGQHAYELAAAAINKNKATGDIGAVARALGA
KTEETALFTAQQPAPALAGETELIRRAFILKEGELGGPVETKKGIYLIKIKERKPAEVPPLAQIRAQVEEKAKTAKAVDL
AKKKAEEAQAKLAKGDSTGLTLRDSGPFAFDAKGNIPTVGASPELMEAAFKLTTAAPAPKEPIRVGARWIAFRLKERTEL
NAANFAAQKEKIKQEILPRKQDDEYRKWIEELRSKAKIEINPALKDI

Sequences:

>Translated_527_residues
MLGIMRKYKQSPVIKVVFGVIVLSFIGTIFLVWGKGEGKLTPSSYAVKVDRTKISYEEFQRTYYRLRDIYVQLYGPALTP
DLEKQLNVKKQALDTLVEGALVRNAARDMGIKVSKDDVQQAIAAMPSFQVNGAFSFNQYVQVLKANRIAPKEFEEGQKDE
LMIKKAQDQIKSRATVSDDEARELFRKRNDRLAISYVSYSPDDVKAEIKLTDQELTDFLAKNQNDFKTPEKISITYVMVD
PLKVGGLEVSEADIQAWYQKNIDRYQGPAGILPLAEVKEKVREDARRFKAGQHAYELAAAAINKNKATGDIGAVARALGA
KTEETALFTAQQPAPALAGETELIRRAFILKEGELGGPVETKKGIYLIKIKERKPAEVPPLAQIRAQVEEKAKTAKAVDL
AKKKAEEAQAKLAKGDSTGLTLRDSGPFAFDAKGNIPTVGASPELMEAAFKLTTAAPAPKEPIRVGARWIAFRLKERTEL
NAANFAAQKEKIKQEILPRKQDDEYRKWIEELRSKAKIEINPALKDI
>Mature_527_residues
MLGIMRKYKQSPVIKVVFGVIVLSFIGTIFLVWGKGEGKLTPSSYAVKVDRTKISYEEFQRTYYRLRDIYVQLYGPALTP
DLEKQLNVKKQALDTLVEGALVRNAARDMGIKVSKDDVQQAIAAMPSFQVNGAFSFNQYVQVLKANRIAPKEFEEGQKDE
LMIKKAQDQIKSRATVSDDEARELFRKRNDRLAISYVSYSPDDVKAEIKLTDQELTDFLAKNQNDFKTPEKISITYVMVD
PLKVGGLEVSEADIQAWYQKNIDRYQGPAGILPLAEVKEKVREDARRFKAGQHAYELAAAAINKNKATGDIGAVARALGA
KTEETALFTAQQPAPALAGETELIRRAFILKEGELGGPVETKKGIYLIKIKERKPAEVPPLAQIRAQVEEKAKTAKAVDL
AKKKAEEAQAKLAKGDSTGLTLRDSGPFAFDAKGNIPTVGASPELMEAAFKLTTAAPAPKEPIRVGARWIAFRLKERTEL
NAANFAAQKEKIKQEILPRKQDDEYRKWIEELRSKAKIEINPALKDI

Specific function: PPIases accelerate the folding of proteins. Seems to be involved in the folding of outer membrane proteins [H]

COG id: COG0760

COG function: function code O; Parvulin-like peptidyl-prolyl isomerase

Gene ontology:

Cell location: Cell inner membrane; Single-pass type II membrane protein; Periplasmic side [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PpiC domain [H]

Homologues:

Organism=Escherichia coli, GI1786645, Length=407, Percent_Identity=23.5872235872236, Blast_Score=122, Evalue=5e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000297
- InterPro:   IPR023058
- InterPro:   IPR015391
- InterPro:   IPR008880 [H]

Pfam domain/function: PF00639 Rotamase; PF09312 SurA_N [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 58729; Mature: 58729

Theoretical pI: Translated: 9.96; Mature: 9.96

Prosite motif: PS50198 PPIC_PPIASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLGIMRKYKQSPVIKVVFGVIVLSFIGTIFLVWGKGEGKLTPSSYAVKVDRTKISYEEFQ
CCCHHHHHHCCCHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCCEEEEEECCCCCHHHHH
RTYYRLRDIYVQLYGPALTPDLEKQLNVKKQALDTLVEGALVRNAARDMGIKVSKDDVQQ
HHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECHHHHHH
AIAAMPSFQVNGAFSFNQYVQVLKANRIAPKEFEEGQKDELMIKKAQDQIKSRATVSDDE
HHHHCCCCEECCCCCHHHHHHHHHHCCCCCHHHCCCCHHHHHHHHHHHHHHHCCCCCCHH
ARELFRKRNDRLAISYVSYSPDDVKAEIKLTDQELTDFLAKNQNDFKTPEKISITYVMVD
HHHHHHHCCCCEEEEEEECCCCCCEEEEEECHHHHHHHHHCCCCCCCCCCEEEEEEEEEC
PLKVGGLEVSEADIQAWYQKNIDRYQGPAGILPLAEVKEKVREDARRFKAGQHAYELAAA
CEEECCEEECHHHHHHHHHHCHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHH
AINKNKATGDIGAVARALGAKTEETALFTAQQPAPALAGETELIRRAFILKEGELGGPVE
HHCCCCCCCHHHHHHHHHCCCCCCCEEEECCCCCCCCCCHHHHHHHHHHHCCCCCCCCCC
TKKGIYLIKIKERKPAEVPPLAQIRAQVEEKAKTAKAVDLAKKKAEEAQAKLAKGDSTGL
CCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCE
TLRDSGPFAFDAKGNIPTVGASPELMEAAFKLTTAAPAPKEPIRVGARWIAFRLKERTEL
EEECCCCEEEECCCCCCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHC
NAANFAAQKEKIKQEILPRKQDDEYRKWIEELRSKAKIEINPALKDI
CHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCEEEECCHHCCC
>Mature Secondary Structure
MLGIMRKYKQSPVIKVVFGVIVLSFIGTIFLVWGKGEGKLTPSSYAVKVDRTKISYEEFQ
CCCHHHHHHCCCHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCCEEEEEECCCCCHHHHH
RTYYRLRDIYVQLYGPALTPDLEKQLNVKKQALDTLVEGALVRNAARDMGIKVSKDDVQQ
HHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECHHHHHH
AIAAMPSFQVNGAFSFNQYVQVLKANRIAPKEFEEGQKDELMIKKAQDQIKSRATVSDDE
HHHHCCCCEECCCCCHHHHHHHHHHCCCCCHHHCCCCHHHHHHHHHHHHHHHCCCCCCHH
ARELFRKRNDRLAISYVSYSPDDVKAEIKLTDQELTDFLAKNQNDFKTPEKISITYVMVD
HHHHHHHCCCCEEEEEEECCCCCCEEEEEECHHHHHHHHHCCCCCCCCCCEEEEEEEEEC
PLKVGGLEVSEADIQAWYQKNIDRYQGPAGILPLAEVKEKVREDARRFKAGQHAYELAAA
CEEECCEEECHHHHHHHHHHCHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHH
AINKNKATGDIGAVARALGAKTEETALFTAQQPAPALAGETELIRRAFILKEGELGGPVE
HHCCCCCCCHHHHHHHHHCCCCCCCEEEECCCCCCCCCCHHHHHHHHHHHCCCCCCCCCC
TKKGIYLIKIKERKPAEVPPLAQIRAQVEEKAKTAKAVDLAKKKAEEAQAKLAKGDSTGL
CCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCE
TLRDSGPFAFDAKGNIPTVGASPELMEAAFKLTTAAPAPKEPIRVGARWIAFRLKERTEL
EEECCCCEEEECCCCCCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHC
NAANFAAQKEKIKQEILPRKQDDEYRKWIEELRSKAKIEINPALKDI
CHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCEEEECCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]