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The map label for this gene is actP [H]

Identifier: 39995625

GI number: 39995625

Start: 551782

End: 553305

Strand: Reverse

Name: actP [H]

Synonym: GSU0518

Alternate gene names: 39995625

Gene position: 553305-551782 (Counterclockwise)

Preceding gene: 39995626

Following gene: 39995624

Centisome position: 14.51

GC content: 65.35

Gene sequence:

>1524_bases
ATGACTGACGCGAATCTCGTCCCCCTCCTTATCGTGACGGCTGCCCTGGCCACCTTCATCATTACCGGGCTGCGGGCACG
GGCGCGGGAAGCGGGAGACTACGGCTTCGGCGGGCGCTACATCGGCCGGATCGGCGGGGGTGCCGCCATTGCCAGCAACT
GGATGAGCGCGGCCAGCTTCCTGGGCATGGGCGGCCTTCTCTACCTCCAGGGCTACTACGCCCTTGCGTACGTCATAGGC
TGGACCGGCGGCTACGTGCTGCTGCTGGTCCTCATGGCCGGCCAGATTCGCCGCTTCGGCAAGTACACGGCCCCGGACTT
CGTGGGGGACCGGTATGCGTCGCCGGGCGCGCGCCTCATCTCGGCGGCCATTTCCATTACTATTTCGGTGATCTACTGCA
CGGCTCAGTTCAAGGGAATCGGCATGCTCTTCGGCTGGCTCTTCGCCACCGACTACCGCACCGGAGTCATTCTGGGCGCC
ACCGTGGCGGTGGGGTACGTAATTCTTTCGGGAATGCTGGGGGTGGCCCGCAACCAGCAGCTCCAGTACACCCTGCTCAT
TGTCTCGTTCATCCTCCCTCTCATGGCCCTGGCTCATAAGCTCGGCTACTTCTGGGTACTCCCCCAGTTCGGCTACGGCG
TTGCCATCCAGGACCTCAAGCGCGAGTTCGGCATCAACTTCGCAGCCCCCTTCGCCTCGGCCGGCCTCTTCCAGTGGGTG
GCCCTCTGCTTCACCCTTATGGTTGGCACCGCCGGTCTTCCCCACGTCCTGTCGCGCTTCTACGTGGTCCCAAACATTCG
CGACGCCCGGTGGAGCCTGGTCTGGGGCCTGTTCTTCATCGCTCTCATCTACTGGTCGGCTCCCGCCTACGCCGTCTTCG
CCCGGCTGCTGGAGGCCCGCTCCGGCATGGCCCCCCCGCCGGTGGCCGCCGGCAAGATGGCCGACATCATCGTGATCAAG
ACCGCAGTCATGGGAGGGCTTCCCTCCTGGATGATCGGCATCCTGGCCGCCGGCGCCATGAGCGCCGCCTTTTTCACAGT
GGCGGGACTGCTCATCACCGGCGCGGCATCCCTTTCCCACGATATCTATTACCGCCTCATCAACCCCCGTGCCTCCGAGG
GTTCCAAGATGGCCCTGGCCAAGGGTGCGGTGGTGGTCCTTGCGGCGATCGTCCTGGCCATCGCACTGAACCCGCCAGGG
CTCATCGCCGAGATCACGGCCGTCGCCTTCGCCCTGGCCGGCAACACGATCTTCCCCGCCTTTCTCCTGGGAATCTGGTG
GAGCCGCGCCAACCGCCACGGTGTCATCGCCGGAATGCTGACCGGCGTCCTCATCACCTTCTCCACCCCCCTGTTCGGTG
GCCTGGTACCGGCGGTGGCGAAGGTCTTCCCCCTCACCTCATCGGCCCTGATCGGCGCGCCGCTGGTGATAGGAGTCATG
ATTGTCGTGTCGCTGCTCACGCCGCCGCCCCCAGAAGCGGTGCGTCGCTTCCTGGCTGAACAGGTTCACGGCCACATGGA
CTGA

Upstream 100 bases:

>100_bases
GGCCAGTTCCTCCCCCTCTGGTTCATCATTCTTTGCGTCCTCTTCAACATCTACATAGACCGGCACACCGAGCAGCACAG
CCGCAGGAGGGACCGCAGCC

Downstream 100 bases:

>100_bases
CGCACGGAACAAGGAGACGCCATGCCGCTCTTTCTCGCGGTAAAAAATGACGATGTCCTTAGCCGCCGGGGAACCGCGGA
CTTCCTGGAAGGGATGCGCC

Product: sodium/solute symporter

Products: NA

Alternate protein names: Acetate permease; Acetate transporter ActP [H]

Number of amino acids: Translated: 507; Mature: 506

Protein sequence:

>507_residues
MTDANLVPLLIVTAALATFIITGLRARAREAGDYGFGGRYIGRIGGGAAIASNWMSAASFLGMGGLLYLQGYYALAYVIG
WTGGYVLLLVLMAGQIRRFGKYTAPDFVGDRYASPGARLISAAISITISVIYCTAQFKGIGMLFGWLFATDYRTGVILGA
TVAVGYVILSGMLGVARNQQLQYTLLIVSFILPLMALAHKLGYFWVLPQFGYGVAIQDLKREFGINFAAPFASAGLFQWV
ALCFTLMVGTAGLPHVLSRFYVVPNIRDARWSLVWGLFFIALIYWSAPAYAVFARLLEARSGMAPPPVAAGKMADIIVIK
TAVMGGLPSWMIGILAAGAMSAAFFTVAGLLITGAASLSHDIYYRLINPRASEGSKMALAKGAVVVLAAIVLAIALNPPG
LIAEITAVAFALAGNTIFPAFLLGIWWSRANRHGVIAGMLTGVLITFSTPLFGGLVPAVAKVFPLTSSALIGAPLVIGVM
IVVSLLTPPPPEAVRRFLAEQVHGHMD

Sequences:

>Translated_507_residues
MTDANLVPLLIVTAALATFIITGLRARAREAGDYGFGGRYIGRIGGGAAIASNWMSAASFLGMGGLLYLQGYYALAYVIG
WTGGYVLLLVLMAGQIRRFGKYTAPDFVGDRYASPGARLISAAISITISVIYCTAQFKGIGMLFGWLFATDYRTGVILGA
TVAVGYVILSGMLGVARNQQLQYTLLIVSFILPLMALAHKLGYFWVLPQFGYGVAIQDLKREFGINFAAPFASAGLFQWV
ALCFTLMVGTAGLPHVLSRFYVVPNIRDARWSLVWGLFFIALIYWSAPAYAVFARLLEARSGMAPPPVAAGKMADIIVIK
TAVMGGLPSWMIGILAAGAMSAAFFTVAGLLITGAASLSHDIYYRLINPRASEGSKMALAKGAVVVLAAIVLAIALNPPG
LIAEITAVAFALAGNTIFPAFLLGIWWSRANRHGVIAGMLTGVLITFSTPLFGGLVPAVAKVFPLTSSALIGAPLVIGVM
IVVSLLTPPPPEAVRRFLAEQVHGHMD
>Mature_506_residues
TDANLVPLLIVTAALATFIITGLRARAREAGDYGFGGRYIGRIGGGAAIASNWMSAASFLGMGGLLYLQGYYALAYVIGW
TGGYVLLLVLMAGQIRRFGKYTAPDFVGDRYASPGARLISAAISITISVIYCTAQFKGIGMLFGWLFATDYRTGVILGAT
VAVGYVILSGMLGVARNQQLQYTLLIVSFILPLMALAHKLGYFWVLPQFGYGVAIQDLKREFGINFAAPFASAGLFQWVA
LCFTLMVGTAGLPHVLSRFYVVPNIRDARWSLVWGLFFIALIYWSAPAYAVFARLLEARSGMAPPPVAAGKMADIIVIKT
AVMGGLPSWMIGILAAGAMSAAFFTVAGLLITGAASLSHDIYYRLINPRASEGSKMALAKGAVVVLAAIVLAIALNPPGL
IAEITAVAFALAGNTIFPAFLLGIWWSRANRHGVIAGMLTGVLITFSTPLFGGLVPAVAKVFPLTSSALIGAPLVIGVMI
VVSLLTPPPPEAVRRFLAEQVHGHMD

Specific function: Transports acetate [H]

COG id: COG4147

COG function: function code R; Predicted symporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family [H]

Homologues:

Organism=Homo sapiens, GI310128183, Length=502, Percent_Identity=24.3027888446215, Blast_Score=75, Evalue=2e-13,
Organism=Escherichia coli, GI1790503, Length=438, Percent_Identity=30.8219178082192, Blast_Score=155, Evalue=6e-39,
Organism=Escherichia coli, GI1787251, Length=499, Percent_Identity=26.25250501002, Blast_Score=106, Evalue=4e-24,
Organism=Escherichia coli, GI87082237, Length=437, Percent_Identity=24.4851258581236, Blast_Score=71, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014083
- InterPro:   IPR001734
- InterPro:   IPR018212
- InterPro:   IPR019900 [H]

Pfam domain/function: PF00474 SSF [H]

EC number: NA

Molecular weight: Translated: 53698; Mature: 53566

Theoretical pI: Translated: 10.13; Mature: 10.13

Prosite motif: PS50283 NA_SOLUT_SYMP_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDANLVPLLIVTAALATFIITGLRARAREAGDYGFGGRYIGRIGGGAAIASNWMSAASF
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHCCCCHHHHHHHHHHHHH
LGMGGLLYLQGYYALAYVIGWTGGYVLLLVLMAGQIRRFGKYTAPDFVGDRYASPGARLI
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHH
SAAISITISVIYCTAQFKGIGMLFGWLFATDYRTGVILGATVAVGYVILSGMLGVARNQQ
HHHHHHHHHEEEEEHHHCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCC
LQYTLLIVSFILPLMALAHKLGYFWVLPQFGYGVAIQDLKREFGINFAAPFASAGLFQWV
HHHHHHHHHHHHHHHHHHHHHCEEEEECCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHH
ALCFTLMVGTAGLPHVLSRFYVVPNIRDARWSLVWGLFFIALIYWSAPAYAVFARLLEAR
HHHHHHHHCCCCHHHHHHHHEECCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
SGMAPPPVAAGKMADIIVIKTAVMGGLPSWMIGILAAGAMSAAFFTVAGLLITGAASLSH
CCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DIYYRLINPRASEGSKMALAKGAVVVLAAIVLAIALNPPGLIAEITAVAFALAGNTIFPA
HHHHEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCHHHHH
FLLGIWWSRANRHGVIAGMLTGVLITFSTPLFGGLVPAVAKVFPLTSSALIGAPLVIGVM
HHHHHHHHCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
IVVSLLTPPPPEAVRRFLAEQVHGHMD
HHHHHCCCCCHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
TDANLVPLLIVTAALATFIITGLRARAREAGDYGFGGRYIGRIGGGAAIASNWMSAASF
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHCCCCHHHHHHHHHHHHH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HHHHHCCCCCHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA