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The map label for this gene is uppP

Identifier: 39995495

GI number: 39995495

Start: 419107

End: 419916

Strand: Reverse

Name: uppP

Synonym: GSU0387

Alternate gene names: 39995495

Gene position: 419916-419107 (Counterclockwise)

Preceding gene: 39995498

Following gene: 39995494

Centisome position: 11.01

GC content: 63.33

Gene sequence:

>810_bases
ATGGACATCATGCACGCAGCGGTCCTCGGCATTCTGCAGGGGCTCACCGAAATACTTCCCATCAGCAGTTCCGCGCACCT
CATCCTTGTCCCCTGGCTTCTGGGATGGCCTGAGTCGGGGCTCACTTTCGACGTGGGGCTACACGTGGGGACCTTGATCG
CACTCTGCGTATACTTCCGCCGTGATATCGCATACTTGATAAGTGATGCCATCACCGGACTGCGGGAAGGCTTCGGGAGC
CAAACGTCCAGGCTCCCGTTCTTCATCATCGCCGGTACCGTACCGGCAGCCATTGCCGGCAAGACCCTGGAGAAGCCCAT
TGAAGAGTTTTTCCGGGGCAGCCACACCCTCATTGCCCTGCTCCTCATCGCCTTCGGCCTTCTCCTGGCGCTGGCCGACA
CCACCGGCCCCAAACGCTGGAGGATGGACCGGGTAGACCTGAGGGGAGCACTGTTGATCGGCCTGGCCCAGTGCCTCGCC
CTGATCCCCGGCGTCTCCCGCTCGGGCATTACCATTACGGCGGCACTGTTCCTCGGCTTTACCCGCGATACGGCAGCCCG
CTTCTCCTTTCTCCTGTCCCTTCCCATCGTGGCCGGAGCCGGCATCCTGAAAATGGGTGAACTGGCCCGCCACGGCATTC
CCGCAGGAGAGCTGGCGCCCCTGCTGGCAGGCATGGCGACATCGGCCGTTTCGGGCTACCTGGGCGTGGCATTGCTCCTC
AGGCTCGTCCAGCGCTACTCCCTCTACCCCTTCGTCTGGTACCGGCTCCTGGCGGGCGGGGCGGTTCTCGCCTACCTTTT
TGCCCGCTGA

Upstream 100 bases:

>100_bases
ACAGCGTTACCGTTCCATGAAAACGCAATCTTTGTTTTGACTTGATTTTCCAAGGGGTTTCATCTACGGTCTAGCGTCGA
CAAAGGGGGAAACACCATCC

Downstream 100 bases:

>100_bases
CCCCGCTTCAATCTTTTAATTATTTTTATTTCATAGTAGAGTTTCCCTCCCGGCCCACGGTCGAGGAACAGTGCATCCAG
GGAGGGACTGCATGGCAGGC

Product: undecaprenol kinase

Products: NA

Alternate protein names: Bacitracin resistance protein; Undecaprenyl pyrophosphate phosphatase

Number of amino acids: Translated: 269; Mature: 269

Protein sequence:

>269_residues
MDIMHAAVLGILQGLTEILPISSSAHLILVPWLLGWPESGLTFDVGLHVGTLIALCVYFRRDIAYLISDAITGLREGFGS
QTSRLPFFIIAGTVPAAIAGKTLEKPIEEFFRGSHTLIALLLIAFGLLLALADTTGPKRWRMDRVDLRGALLIGLAQCLA
LIPGVSRSGITITAALFLGFTRDTAARFSFLLSLPIVAGAGILKMGELARHGIPAGELAPLLAGMATSAVSGYLGVALLL
RLVQRYSLYPFVWYRLLAGGAVLAYLFAR

Sequences:

>Translated_269_residues
MDIMHAAVLGILQGLTEILPISSSAHLILVPWLLGWPESGLTFDVGLHVGTLIALCVYFRRDIAYLISDAITGLREGFGS
QTSRLPFFIIAGTVPAAIAGKTLEKPIEEFFRGSHTLIALLLIAFGLLLALADTTGPKRWRMDRVDLRGALLIGLAQCLA
LIPGVSRSGITITAALFLGFTRDTAARFSFLLSLPIVAGAGILKMGELARHGIPAGELAPLLAGMATSAVSGYLGVALLL
RLVQRYSLYPFVWYRLLAGGAVLAYLFAR
>Mature_269_residues
MDIMHAAVLGILQGLTEILPISSSAHLILVPWLLGWPESGLTFDVGLHVGTLIALCVYFRRDIAYLISDAITGLREGFGS
QTSRLPFFIIAGTVPAAIAGKTLEKPIEEFFRGSHTLIALLLIAFGLLLALADTTGPKRWRMDRVDLRGALLIGLAQCLA
LIPGVSRSGITITAALFLGFTRDTAARFSFLLSLPIVAGAGILKMGELARHGIPAGELAPLLAGMATSAVSGYLGVALLL
RLVQRYSLYPFVWYRLLAGGAVLAYLFAR

Specific function: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin

COG id: COG1968

COG function: function code V; Uncharacterized bacitracin resistance protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uppP family

Homologues:

Organism=Escherichia coli, GI1789437, Length=276, Percent_Identity=34.7826086956522, Blast_Score=139, Evalue=1e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): UPPP_GEOSL (P60938)

Other databases:

- EMBL:   AE017180
- RefSeq:   NP_951446.1
- GeneID:   2686573
- GenomeReviews:   AE017180_GR
- KEGG:   gsu:GSU0387
- NMPDR:   fig|243231.1.peg.384
- TIGR:   GSU0387
- HOGENOM:   HBG391969
- OMA:   SAYICVK
- ProtClustDB:   CLSK827794
- BioCyc:   GSUL243231:GSU_0387-MONOMER
- BRENDA:   3.6.1.27
- GO:   GO:0016311
- HAMAP:   MF_01006
- InterPro:   IPR003824
- TIGRFAMs:   TIGR00753

Pfam domain/function: PF02673 BacA

EC number: =3.6.1.27

Molecular weight: Translated: 28743; Mature: 28743

Theoretical pI: Translated: 9.67; Mature: 9.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xc810f54)-; HASH(0xc19e67c)-; HASH(0xbccece0)-; HASH(0xaefc694)-; HASH(0xb3b9614)-; HASH(0xc6e5bb8)-; HASH(0xaf4d360)-; HASH(0xc2c2250)-;

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDIMHAAVLGILQGLTEILPISSSAHLILVPWLLGWPESGLTFDVGLHVGTLIALCVYFR
CCHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHCCCCCCCEEEHHHHHHHHHHHHHHHH
RDIAYLISDAITGLREGFGSQTSRLPFFIIAGTVPAAIAGKTLEKPIEEFFRGSHTLIAL
HHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHCCCHHHHHH
LLIAFGLLLALADTTGPKRWRMDRVDLRGALLIGLAQCLALIPGVSRSGITITAALFLGF
HHHHHHHHHHHHCCCCCHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHH
TRDTAARFSFLLSLPIVAGAGILKMGELARHGIPAGELAPLLAGMATSAVSGYLGVALLL
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
RLVQRYSLYPFVWYRLLAGGAVLAYLFAR
HHHHHHCCHHHHHHHHHHHHHHHHHHHCH
>Mature Secondary Structure
MDIMHAAVLGILQGLTEILPISSSAHLILVPWLLGWPESGLTFDVGLHVGTLIALCVYFR
CCHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHCCCCCCCEEEHHHHHHHHHHHHHHHH
RDIAYLISDAITGLREGFGSQTSRLPFFIIAGTVPAAIAGKTLEKPIEEFFRGSHTLIAL
HHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHCCCHHHHHH
LLIAFGLLLALADTTGPKRWRMDRVDLRGALLIGLAQCLALIPGVSRSGITITAALFLGF
HHHHHHHHHHHHCCCCCHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHH
TRDTAARFSFLLSLPIVAGAGILKMGELARHGIPAGELAPLLAGMATSAVSGYLGVALLL
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
RLVQRYSLYPFVWYRLLAGGAVLAYLFAR
HHHHHHCCHHHHHHHHHHHHHHHHHHHCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA