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The map label for this gene is zur [H]

Identifier: 38234281

GI number: 38234281

Start: 1747858

End: 1748286

Strand: Direct

Name: zur [H]

Synonym: DIP1710

Alternate gene names: 38234281

Gene position: 1747858-1748286 (Clockwise)

Preceding gene: 38234280

Following gene: 38234297

Centisome position: 70.23

GC content: 51.52

Gene sequence:

>429_bases
ATGAATCGCACCATTGATCGTTCGGTCCCGAAGTTGGGGGTTCGTAGCACCCGGCAGCGCACTGCTGTCGTTGGGGTTCT
CAAAGATCTTGATTATTTCGCTTCTGCCAAAGTGATTCATCAAGAACTGACTAAACGTGATCTCAAGGTCGGTCTGACAA
CTGTGTACCGAACCTTGCAATCACTTTCAGAAATCGAAGCAGTCGATGTCCTCCATATGTCCAATGGCGAAACCCTCTAC
CGCCACTGCTTGAGCGATGAACACCACCACCACTTGGTGTGCACTGAATGTGGCCGCACCGTGGAGATCGATGGCGGCCC
AGTAGAAAAGTGGGCTAAAGAAGTAGCCCAGCTACATGGATTCCAAGTAACTGGGCACGATGCCGAAATCTACGGCCTCT
GCGAAAGCTGCTCTGCAGCAACCGAATAA

Upstream 100 bases:

>100_bases
CATCTCAACATTCTGTTGAAAAAGGAGTACGCTTAGTGTTGAAAGAGTTCTTGCCACACTCTCTTTAACTGCCACATCGC
AAAAACTTAAGGAATGCTCC

Downstream 100 bases:

>100_bases
CTCTTTTTATCCGAGCGCTACTCCAAACGCTTTGCCTAAGAGGTAGGTCACACCCGCTGCGGCCATACCAATGGCAAGCT
GGCGAAGCGCTCTTTTTAGT

Product: putative ferric uptake regulatory protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 142; Mature: 142

Protein sequence:

>142_residues
MNRTIDRSVPKLGVRSTRQRTAVVGVLKDLDYFASAKVIHQELTKRDLKVGLTTVYRTLQSLSEIEAVDVLHMSNGETLY
RHCLSDEHHHHLVCTECGRTVEIDGGPVEKWAKEVAQLHGFQVTGHDAEIYGLCESCSAATE

Sequences:

>Translated_142_residues
MNRTIDRSVPKLGVRSTRQRTAVVGVLKDLDYFASAKVIHQELTKRDLKVGLTTVYRTLQSLSEIEAVDVLHMSNGETLY
RHCLSDEHHHHLVCTECGRTVEIDGGPVEKWAKEVAQLHGFQVTGHDAEIYGLCESCSAATE
>Mature_142_residues
MNRTIDRSVPKLGVRSTRQRTAVVGVLKDLDYFASAKVIHQELTKRDLKVGLTTVYRTLQSLSEIEAVDVLHMSNGETLY
RHCLSDEHHHHLVCTECGRTVEIDGGPVEKWAKEVAQLHGFQVTGHDAEIYGLCESCSAATE

Specific function: Required for the zinc-specific repression of two operons implicated in zinc uptake, yciC and ycdHIyceA. Also represses the expression of rpmE2, the gene for ribosomal protein L31B, which is expressed only after the end of exponential growth [H]

COG id: COG0735

COG function: function code P; Fe2+/Zn2+ uptake regulation proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Fur family [H]

Homologues:

Organism=Escherichia coli, GI1786899, Length=129, Percent_Identity=30.2325581395349, Blast_Score=73, Evalue=7e-15,

Paralogues:

None

Copy number: 3432 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002481 [H]

Pfam domain/function: PF01475 FUR [H]

EC number: NA

Molecular weight: Translated: 15844; Mature: 15844

Theoretical pI: Translated: 6.59; Mature: 6.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.5 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
3.5 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRTIDRSVPKLGVRSTRQRTAVVGVLKDLDYFASAKVIHQELTKRDLKVGLTTVYRTLQ
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SLSEIEAVDVLHMSNGETLYRHCLSDEHHHHLVCTECGRTVEIDGGPVEKWAKEVAQLHG
HHHHHHHHHHEECCCCHHHHHHHCCCCCCCEEEEECCCCEEEECCCCHHHHHHHHHHHCC
FQVTGHDAEIYGLCESCSAATE
CEEECCCHHHHHHHHHHCCCCC
>Mature Secondary Structure
MNRTIDRSVPKLGVRSTRQRTAVVGVLKDLDYFASAKVIHQELTKRDLKVGLTTVYRTLQ
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SLSEIEAVDVLHMSNGETLYRHCLSDEHHHHLVCTECGRTVEIDGGPVEKWAKEVAQLHG
HHHHHHHHHHEECCCCHHHHHHHCCCCCCCEEEEECCCCEEEECCCCHHHHHHHHHHHCC
FQVTGHDAEIYGLCESCSAATE
CEEECCCHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377; 9811636 [H]