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The map label for this gene is aceE [H]

Identifier: 38234258

GI number: 38234258

Start: 1723276

End: 1726011

Strand: Direct

Name: aceE [H]

Synonym: DIP1687

Alternate gene names: 38234258

Gene position: 1723276-1726011 (Clockwise)

Preceding gene: 38234255

Following gene: 38234259

Centisome position: 69.25

GC content: 57.24

Gene sequence:

>2736_bases
ATGTCAGACCCTAATGAGGGTATGCGCCCTGAAGACAGCAACTTCGCAATGATCCGCGACGGTGTTGCTTCATATCTCAA
CGACGCCGACCCAGAAGAGACTCGCGAATGGATGGAATCTCTCGATGGCATGCTCGAGGGTTCCAGTCCCGATCGTGCCC
GATTCCTGATGCTGCGTCTCCTCGAGCGCGCTTCAGCCCGTCGCGTTCCACTACCACCGATGACGTCGACAGACTTTGTC
AACACCATTCCCACCACGATGGAACCTGAATTCCCCGGTGACGAGGAAATTGAGAAACGCTACCGTCGTTGGATCCGCTG
GAATGCTGCCATCATGGTTCACCGCGCCCAGCGCCCAGGCATTGGCGTTGGTGGACACATCTCCACCTACGCTGGTGCAG
CACCACTGTATGAAGTCGGCTTCAACCACTTCTTCCGCGGCAAGGACCACCCAGGTGGTGGCGACCATGTGTTCTTCCAA
GGCCACGCTTCCCCAGGTATGTATGCCCGTGCATTCATGGAAGGTCGTCTGACCGAAGACGACCTCGATGGCTTCCGCCA
AGAAGTATCGCGTCCACAGGGGGGACTCCCCTCCTACCCCCACCCTCACGGTATGAAGGACTTCTGGGAGTTCCCGACCG
TGTCAATGGGCCTTGGCCCAATGGACGCTATTTACCAAGCACGCTTTAACCGCTACCTTCACAACCGCGGCATCAAGGAC
ACCTCACAGCAGCACGTCTGGGCGTTCCTTGGCGACGGCGAAATGGATGAGCCAGAATCTCGCGGCCTCATTCAGATGGC
AGCGTTGAATAACTTGGACAACCTGACCTTCGTTGTTAACTGCAACTTGCAGCGTCTCGACGGCCCTGTTCGCGGTAACA
CCAAGATCATTCAAGAGCTGGAGTCCTTCTTCCGCGGCGCCGGCTGGTCTGTTATCAAGGTTGTTTGGGGACGCGAGTGG
GATCAGCTCTTCGAAGCTGATAAGGATGGTGCTCTCGTCGACCTCATGAATACCACCTCTGATGGTGACTTCCAGACCTT
TAAGGCTAACGACGGCGCCTACGTGCGCGAGCACTTCTTCAACCGCGATCCACGCACCGCCAAGCTTGTCGAAGACTGGT
CGGATGAAGACATCTGGAAGCTGCGCCGCGGTGGTCACGACTACCGCAAGATCTACGCTGCATTCCAGCGCGCGCTTGAG
ACAAAGGATCGCCCAACCGTGATTCTTGCTCACACCATTAAGGGCTACGGCTTGGGCCACAACTTCGAGGGCCGCAATGC
CACCCACCAGATGAAGAAGCTCACTCTGGACGATCTCAAGCAGTTCCGCGATAAGCAGGGCGTACCAATTACCGACGAAG
AATTGGAAAAGGATCCATATCTTCCTCCGTACTACCACCCAGGCGAGGATGCCCCAGAGATCAAGTACCTCTTGGAGCGT
CGTAAGTCTTTGGGCGGATTCGTACCGGAGCGTCGCGAATCCTACACCCCGCTGCATGTCCCCGAGCTCGACAAGCTCCG
CAGCCTTCGTAAAGGCTCCGGCAAGCAGCAAGTCGCCACCACTATGGCCGTGGTTCGCGCCTTCAAGGAACTCATGCGCG
ACCCAGAGCTGGGCAAGCGCATCGTCCCGATCATTCCTGACGAGGCTCGTACCTTCGGCATGGACTCATGGTTCCCAACC
ATGAAGATCTACAACCCACATGGTCAAAACTATGTGCCAGTAGACCATGACCTCATGCTTTCCTACCGTGAGGCCAAGGA
CGGCCAAATCCTCCACGAGGGCATCAACGAAGCCGGATCTACCGCTTCCTTCATTGCTGCAGCTACGTCCTACGCCACCC
ACGGCGAAGCCATGATCCCGCTGTACATCTTCTACTCGATGTTCGGTTTCCAGCGCACTGGCGATTCCTTCTGGGCAGCA
GGCGACCAAATGGCACGTGGCTTCATCTTGGGCGCAACCGCCGGTCGTACAACCTTGACAGGCGAAGGCCTCCAGCACAT
GGATGGTCACTCCCAGATCTTGGCCTCGACCAACCCAGCGGTCGTTTCCTACGACCCAGCATTCTCCTACGAGATTGCCC
ACCTTCTGCGCGAAGGTATCGACCGCATGTACGGCCCAGGCCGTGGTGAGGACGTGATGTACTACCTCACCATCTACAAC
GAGCCAATTTCACAGCCAGCCGAGCCAGAGGACTTGGACGTTGAGGGCCTACACAAGGGCGTTTACCTTTACGAAAAGGC
AGACGGTGGCGAGCACGAGGTGTCCCTCTTGGCGTCCGGCATTGGTATGCAACAAGCACTGCGCGCCAAAGAGATTCTTC
GCGACGAGTTCAACATCGGCGCTAACATCTTCTCGGTTACTTCTTGGGTAGAGTTGGCACGCGAAGGACACGCCAAGGAA
CGTGAGGCACTGCGCAACCCAGGAATTGAGCAGGAAGAGGCGTTTGCCACCACCCAACTCAAGAAGGGCTCCGGACCGTA
CATCGCCGTTTCCGACTTTGCTACCGATCTGCAAGAACAGATCCGCCGCTTTGTCCCAGGCGACTACACCACCTTGGGCG
CCGACGGCTTCGGCTTCTCCGATACCCGCCCAGCCGCCCGTCGCTTCTTCAACATCGATGCCGAGTCCGTTGTTGTCGCA
GCACTGAATGGCTTAGTAAAGCAAGGCAAGATTGATCGCAGCGTTGCAGCCGAAGCAGCTCAGCGTTTCAACCTCACCGA
CCCAACCAAAGCTTAA

Upstream 100 bases:

>100_bases
AGTATCCTGTAGTAAAACCTGTGGTGCTGTCACCATGTTTGGAGTACTCACCCATTCGTGGCCGACACCCACACGACACG
TACAACTATGGAGGTGGCGA

Downstream 100 bases:

>100_bases
AGATTAAATCCAAAAATGTACCGTCACCACATAATTTCTTATGTGGTGACGGTACATTTTTGGTGAAACCGCTCAAGAAA
CTAAATTATTTCTCACTCGG

Product: pyruvate dehydrogenase subunit E1

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 911; Mature: 910

Protein sequence:

>911_residues
MSDPNEGMRPEDSNFAMIRDGVASYLNDADPEETREWMESLDGMLEGSSPDRARFLMLRLLERASARRVPLPPMTSTDFV
NTIPTTMEPEFPGDEEIEKRYRRWIRWNAAIMVHRAQRPGIGVGGHISTYAGAAPLYEVGFNHFFRGKDHPGGGDHVFFQ
GHASPGMYARAFMEGRLTEDDLDGFRQEVSRPQGGLPSYPHPHGMKDFWEFPTVSMGLGPMDAIYQARFNRYLHNRGIKD
TSQQHVWAFLGDGEMDEPESRGLIQMAALNNLDNLTFVVNCNLQRLDGPVRGNTKIIQELESFFRGAGWSVIKVVWGREW
DQLFEADKDGALVDLMNTTSDGDFQTFKANDGAYVREHFFNRDPRTAKLVEDWSDEDIWKLRRGGHDYRKIYAAFQRALE
TKDRPTVILAHTIKGYGLGHNFEGRNATHQMKKLTLDDLKQFRDKQGVPITDEELEKDPYLPPYYHPGEDAPEIKYLLER
RKSLGGFVPERRESYTPLHVPELDKLRSLRKGSGKQQVATTMAVVRAFKELMRDPELGKRIVPIIPDEARTFGMDSWFPT
MKIYNPHGQNYVPVDHDLMLSYREAKDGQILHEGINEAGSTASFIAAATSYATHGEAMIPLYIFYSMFGFQRTGDSFWAA
GDQMARGFILGATAGRTTLTGEGLQHMDGHSQILASTNPAVVSYDPAFSYEIAHLLREGIDRMYGPGRGEDVMYYLTIYN
EPISQPAEPEDLDVEGLHKGVYLYEKADGGEHEVSLLASGIGMQQALRAKEILRDEFNIGANIFSVTSWVELAREGHAKE
REALRNPGIEQEEAFATTQLKKGSGPYIAVSDFATDLQEQIRRFVPGDYTTLGADGFGFSDTRPAARRFFNIDAESVVVA
ALNGLVKQGKIDRSVAAEAAQRFNLTDPTKA

Sequences:

>Translated_911_residues
MSDPNEGMRPEDSNFAMIRDGVASYLNDADPEETREWMESLDGMLEGSSPDRARFLMLRLLERASARRVPLPPMTSTDFV
NTIPTTMEPEFPGDEEIEKRYRRWIRWNAAIMVHRAQRPGIGVGGHISTYAGAAPLYEVGFNHFFRGKDHPGGGDHVFFQ
GHASPGMYARAFMEGRLTEDDLDGFRQEVSRPQGGLPSYPHPHGMKDFWEFPTVSMGLGPMDAIYQARFNRYLHNRGIKD
TSQQHVWAFLGDGEMDEPESRGLIQMAALNNLDNLTFVVNCNLQRLDGPVRGNTKIIQELESFFRGAGWSVIKVVWGREW
DQLFEADKDGALVDLMNTTSDGDFQTFKANDGAYVREHFFNRDPRTAKLVEDWSDEDIWKLRRGGHDYRKIYAAFQRALE
TKDRPTVILAHTIKGYGLGHNFEGRNATHQMKKLTLDDLKQFRDKQGVPITDEELEKDPYLPPYYHPGEDAPEIKYLLER
RKSLGGFVPERRESYTPLHVPELDKLRSLRKGSGKQQVATTMAVVRAFKELMRDPELGKRIVPIIPDEARTFGMDSWFPT
MKIYNPHGQNYVPVDHDLMLSYREAKDGQILHEGINEAGSTASFIAAATSYATHGEAMIPLYIFYSMFGFQRTGDSFWAA
GDQMARGFILGATAGRTTLTGEGLQHMDGHSQILASTNPAVVSYDPAFSYEIAHLLREGIDRMYGPGRGEDVMYYLTIYN
EPISQPAEPEDLDVEGLHKGVYLYEKADGGEHEVSLLASGIGMQQALRAKEILRDEFNIGANIFSVTSWVELAREGHAKE
REALRNPGIEQEEAFATTQLKKGSGPYIAVSDFATDLQEQIRRFVPGDYTTLGADGFGFSDTRPAARRFFNIDAESVVVA
ALNGLVKQGKIDRSVAAEAAQRFNLTDPTKA
>Mature_910_residues
SDPNEGMRPEDSNFAMIRDGVASYLNDADPEETREWMESLDGMLEGSSPDRARFLMLRLLERASARRVPLPPMTSTDFVN
TIPTTMEPEFPGDEEIEKRYRRWIRWNAAIMVHRAQRPGIGVGGHISTYAGAAPLYEVGFNHFFRGKDHPGGGDHVFFQG
HASPGMYARAFMEGRLTEDDLDGFRQEVSRPQGGLPSYPHPHGMKDFWEFPTVSMGLGPMDAIYQARFNRYLHNRGIKDT
SQQHVWAFLGDGEMDEPESRGLIQMAALNNLDNLTFVVNCNLQRLDGPVRGNTKIIQELESFFRGAGWSVIKVVWGREWD
QLFEADKDGALVDLMNTTSDGDFQTFKANDGAYVREHFFNRDPRTAKLVEDWSDEDIWKLRRGGHDYRKIYAAFQRALET
KDRPTVILAHTIKGYGLGHNFEGRNATHQMKKLTLDDLKQFRDKQGVPITDEELEKDPYLPPYYHPGEDAPEIKYLLERR
KSLGGFVPERRESYTPLHVPELDKLRSLRKGSGKQQVATTMAVVRAFKELMRDPELGKRIVPIIPDEARTFGMDSWFPTM
KIYNPHGQNYVPVDHDLMLSYREAKDGQILHEGINEAGSTASFIAAATSYATHGEAMIPLYIFYSMFGFQRTGDSFWAAG
DQMARGFILGATAGRTTLTGEGLQHMDGHSQILASTNPAVVSYDPAFSYEIAHLLREGIDRMYGPGRGEDVMYYLTIYNE
PISQPAEPEDLDVEGLHKGVYLYEKADGGEHEVSLLASGIGMQQALRAKEILRDEFNIGANIFSVTSWVELAREGHAKER
EALRNPGIEQEEAFATTQLKKGSGPYIAVSDFATDLQEQIRRFVPGDYTTLGADGFGFSDTRPAARRFFNIDAESVVVAA
LNGLVKQGKIDRSVAAEAAQRFNLTDPTKA

Specific function: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components:pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydroge

COG id: COG2609

COG function: function code C; Pyruvate dehydrogenase complex, dehydrogenase (E1) component

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1786304, Length=882, Percent_Identity=51.1337868480726, Blast_Score=912, Evalue=0.0,

Paralogues:

None

Copy number: 1140 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 400 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). 6,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004660
- InterPro:   IPR009014
- InterPro:   IPR015941
- InterPro:   IPR005474 [H]

Pfam domain/function: PF00456 Transketolase_N [H]

EC number: =1.2.4.1 [H]

Molecular weight: Translated: 102510; Mature: 102379

Theoretical pI: Translated: 5.36; Mature: 5.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDPNEGMRPEDSNFAMIRDGVASYLNDADPEETREWMESLDGMLEGSSPDRARFLMLRL
CCCCCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
LERASARRVPLPPMTSTDFVNTIPTTMEPEFPGDEEIEKRYRRWIRWNAAIMVHRAQRPG
HHHHHCCCCCCCCCCCCCHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCEEEEEECCCCC
IGVGGHISTYAGAAPLYEVGFNHFFRGKDHPGGGDHVFFQGHASPGMYARAFMEGRLTED
CCCCCCHHHHCCCCHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCCHHHHHHHHCCCCHH
DLDGFRQEVSRPQGGLPSYPHPHGMKDFWEFPTVSMGLGPMDAIYQARFNRYLHNRGIKD
HHHHHHHHHCCCCCCCCCCCCCCCCHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCC
TSQQHVWAFLGDGEMDEPESRGLIQMAALNNLDNLTFVVNCNLQRLDGPVRGNTKIIQEL
CCCCEEEEEECCCCCCCCCCCCEEEEEHHCCCCCEEEEEECCHHHCCCCCCCCHHHHHHH
ESFFRGAGWSVIKVVWGREWDQLFEADKDGALVDLMNTTSDGDFQTFKANDGAYVREHFF
HHHHCCCCCEEEHEECCCCHHHHHCCCCCCCEEEEECCCCCCCEEEEECCCCHHHHHHHC
NRDPRTAKLVEDWSDEDIWKLRRGGHDYRKIYAAFQRALETKDRPTVILAHTIKGYGLGH
CCCCCHHHHHHCCCCHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCC
NFEGRNATHQMKKLTLDDLKQFRDKQGVPITDEELEKDPYLPPYYHPGEDAPEIKYLLER
CCCCCCHHHHHHHCCHHHHHHHHHCCCCCCCHHHHCCCCCCCCCCCCCCCCHHHHHHHHH
RKSLGGFVPERRESYTPLHVPELDKLRSLRKGSGKQQVATTMAVVRAFKELMRDPELGKR
HHHHCCCCCCHHCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCHHHCCE
IVPIIPDEARTFGMDSWFPTMKIYNPHGQNYVPVDHDLMLSYREAKDGQILHEGINEAGS
EECCCCCCHHHCCCCCCCCCEEEECCCCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHCCC
TASFIAAATSYATHGEAMIPLYIFYSMFGFQRTGDSFWAAGDQMARGFILGATAGRTTLT
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCHHHHCCHHHHCCEEEECCCCCCEEC
GEGLQHMDGHSQILASTNPAVVSYDPAFSYEIAHLLREGIDRMYGPGRGEDVMYYLTIYN
CCCHHHCCCCHHEEECCCCCEEEECCCHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEEC
EPISQPAEPEDLDVEGLHKGVYLYEKADGGEHEVSLLASGIGMQQALRAKEILRDEFNIG
CCCCCCCCCCCCCHHHHCCCEEEEECCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHCCC
ANIFSVTSWVELAREGHAKEREALRNPGIEQEEAFATTQLKKGSGPYIAVSDFATDLQEQ
CHHHHHHHHHHHHHHCCHHHHHHHHCCCCCHHHHHHHHHHCCCCCCEEEEHHHHHHHHHH
IRRFVPGDYTTLGADGFGFSDTRPAARRFFNIDAESVVVAALNGLVKQGKIDRSVAAEAA
HHHHCCCCCEEECCCCCCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHH
QRFNLTDPTKA
HHCCCCCCCCC
>Mature Secondary Structure 
SDPNEGMRPEDSNFAMIRDGVASYLNDADPEETREWMESLDGMLEGSSPDRARFLMLRL
CCCCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
LERASARRVPLPPMTSTDFVNTIPTTMEPEFPGDEEIEKRYRRWIRWNAAIMVHRAQRPG
HHHHHCCCCCCCCCCCCCHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCEEEEEECCCCC
IGVGGHISTYAGAAPLYEVGFNHFFRGKDHPGGGDHVFFQGHASPGMYARAFMEGRLTED
CCCCCCHHHHCCCCHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCCHHHHHHHHCCCCHH
DLDGFRQEVSRPQGGLPSYPHPHGMKDFWEFPTVSMGLGPMDAIYQARFNRYLHNRGIKD
HHHHHHHHHCCCCCCCCCCCCCCCCHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCC
TSQQHVWAFLGDGEMDEPESRGLIQMAALNNLDNLTFVVNCNLQRLDGPVRGNTKIIQEL
CCCCEEEEEECCCCCCCCCCCCEEEEEHHCCCCCEEEEEECCHHHCCCCCCCCHHHHHHH
ESFFRGAGWSVIKVVWGREWDQLFEADKDGALVDLMNTTSDGDFQTFKANDGAYVREHFF
HHHHCCCCCEEEHEECCCCHHHHHCCCCCCCEEEEECCCCCCCEEEEECCCCHHHHHHHC
NRDPRTAKLVEDWSDEDIWKLRRGGHDYRKIYAAFQRALETKDRPTVILAHTIKGYGLGH
CCCCCHHHHHHCCCCHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCC
NFEGRNATHQMKKLTLDDLKQFRDKQGVPITDEELEKDPYLPPYYHPGEDAPEIKYLLER
CCCCCCHHHHHHHCCHHHHHHHHHCCCCCCCHHHHCCCCCCCCCCCCCCCCHHHHHHHHH
RKSLGGFVPERRESYTPLHVPELDKLRSLRKGSGKQQVATTMAVVRAFKELMRDPELGKR
HHHHCCCCCCHHCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCHHHCCE
IVPIIPDEARTFGMDSWFPTMKIYNPHGQNYVPVDHDLMLSYREAKDGQILHEGINEAGS
EECCCCCCHHHCCCCCCCCCEEEECCCCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHCCC
TASFIAAATSYATHGEAMIPLYIFYSMFGFQRTGDSFWAAGDQMARGFILGATAGRTTLT
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCHHHHCCHHHHCCEEEECCCCCCEEC
GEGLQHMDGHSQILASTNPAVVSYDPAFSYEIAHLLREGIDRMYGPGRGEDVMYYLTIYN
CCCHHHCCCCHHEEECCCCCEEEECCCHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEEC
EPISQPAEPEDLDVEGLHKGVYLYEKADGGEHEVSLLASGIGMQQALRAKEILRDEFNIG
CCCCCCCCCCCCCHHHHCCCEEEEECCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHCCC
ANIFSVTSWVELAREGHAKEREALRNPGIEQEEAFATTQLKKGSGPYIAVSDFATDLQEQ
CHHHHHHHHHHHHHHCCHHHHHHHHCCCCCHHHHHHHHHHCCCCCCEEEEHHHHHHHHHH
IRRFVPGDYTTLGADGFGFSDTRPAARRFFNIDAESVVVAALNGLVKQGKIDRSVAAEAA
HHHHCCCCCEEECCCCCCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHH
QRFNLTDPTKA
HHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA