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The map label for this gene is asnB [H]

Identifier: 38234205

GI number: 38234205

Start: 1663954

End: 1665876

Strand: Direct

Name: asnB [H]

Synonym: DIP1630

Alternate gene names: 38234205

Gene position: 1663954-1665876 (Clockwise)

Preceding gene: 38234190

Following gene: 38234207

Centisome position: 66.86

GC content: 50.44

Gene sequence:

>1923_bases
ATGTGTGGACTTCTAGGCATGCTCTCCAGCACAGGACAGGCCAGTAAGTATGCAGCTGCTATAGAAAGTGCTTTGCCGTG
CATGCACCACCGAGGCCCTGACGAAGCAGGTACTTGGCATGACGACCATGCAGTTTTTGGCTTTAATCGCCTATCGATCA
TCGATCTCGAGCATTCTCACCAGCCCTTGCGATGGGGGCCTGAAGGCGAGCCCGACCGCTATGCCATGACTTTTAATGGC
GAGATCTACAACTATGTAGAGCTACGAAAAAAACTTCAAGACCTCGGCTACACCTTTAACACTTCAGGCGACGGCGAAAC
TATTGCTGTCGGTTTCCACCACTGGGGTGCAGATGTAGTGCTTCACTTGCGCGGAATGTTTGGCATAGCCATCTGGGACA
CCAAGGAACAACGTCTTTTCTTGGCCCGCGATCAATTTGGCATCAAGCCGTTGTACTTTGCTACTACCGAAGCTGGCACC
GTTTTCGCCTCGGAGAAAAAGTGCATCTTGGGTATGGCAGATGCTATTGGTCTAGATTTAGGACTTGACCAACGTGCTAT
CGAACACTACATCGATCTTCAATACGTTCCAGAGCCTGAAAGTCTTCATCAGCACATTCGACGCCTGGAGTCTGGCTGCT
TTGCTTTCGTTTCTGTGGGAGGCAATGTCGAGCAGACTCGTTACTTCCGTCCTCAGTTCCCCGCACAAGAATTCCCAAAG
GACAAGGAACAGGATCTCTTCGATCGAATCGCCAAGGCCCTAGAAGATAGCGTCGAAAAGCACATGCGTGCCGACGTCAC
TGTCGGTTCTTTCCTGTCTGGCGGCATCGACTCCACTGCGATTGCAACTTTGGCAAAACGCCATAATCCGAATCTGTTGA
CATTCACTACAGGATTTGAACGCGAAGGATATTCGGAAGTCGATGTGGCTGCAGAATCCGCTGCTGCCATTGGAGTAGAA
CATATCGTTAAGATTGTCTCTCCCGAGGAATATGCCAATGCCATTCCTCAAATCATGTGGTACTTGGATGATCCAGTAGC
TGATCCCTCCCTAGTCCCACTATTCTTCGTTGCTCAAGAAGCCCGCAAGCATGTCAAAGTGGTGTTGTCAGGCGAAGGAG
CAGACGAACTATTTGGTGGTTACACCATTTACAAAGAGCCGCTTTCTCTTGCTCCATTTGAAAAGATTCCTTCCCCGCTA
CGTCGCGGTCTTGGCAAAGTAGCCGAAGTTTTCCCTGACGGAATGCGTGGTAAATCCTTGCTCCAACGCGGTTCGATGAC
GATGGAAGAGCGTTATTACGGAAATGCTCGTTCCTTCAATTTTGATCAAATGAAGCGCGTTATCCCATGGGCCAAGAAGG
AATGGGATCACCGCGAAGTCACCGCACCGATCTACGCCCAGTCTGAGCACATGGACCCCGTTGCGCGAATGCAGCATTTG
GACCTTTTCACGTGGATGCGCGGCGATATCCTCGTCAAGGCCGACAAGATCAACATGGCTCACTCCTTGGAGCTTCGCGT
CCCGTTCTTGGATAAGGAAGTATTTGAGGTTGCTGAAACCATTCCTTATGACCTCAAGATTGCTAACGGAACGACCAAAT
ATGCGTTGCGTAAGGCCATGGAACAAATCGTTCCGCCGCACGTGCTACACCGCAAGAAACTCGGATTCCCAGTGCCTATG
CGCCACTGGCTAGCTGGCGATGAGCTGTTCGGTTGGGCTCAAGACACCATTAATGAGTCGATGACCGACCAATACTTTGA
CAAGGCAGCAGTCTTAGCAATGCTCAATGAGCACAAGAATGGTGTATCTGATCATTCCCGCAGGCTATGGACAGTCCTTG
CCTTTATGATTTGGCACGGAATTTTCGTCGAGCACCGCATTGATCCAGGCATCGAGAAACGCGATTATCCTGTGTACCTA
TAG

Upstream 100 bases:

>100_bases
TGTTCCCTCGATACGCGGTAGCGATTCAATCCCCCATCGTTGTTTCGGGGTAACGTAAGACAATCCGGAAGTTACCAATA
GACGAGGAGGATCTGCTCAC

Downstream 100 bases:

>100_bases
GCGATTGCTTGCTCAGCAACTCCATATAAAAAGATCCCGCTAGTTCTCCTAGAAAAACAACGGAGAACTAGCGGGAATTT
TTATTTACGTTTAGTTAAAT

Product: putative asparagine synthetase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 640; Mature: 640

Protein sequence:

>640_residues
MCGLLGMLSSTGQASKYAAAIESALPCMHHRGPDEAGTWHDDHAVFGFNRLSIIDLEHSHQPLRWGPEGEPDRYAMTFNG
EIYNYVELRKKLQDLGYTFNTSGDGETIAVGFHHWGADVVLHLRGMFGIAIWDTKEQRLFLARDQFGIKPLYFATTEAGT
VFASEKKCILGMADAIGLDLGLDQRAIEHYIDLQYVPEPESLHQHIRRLESGCFAFVSVGGNVEQTRYFRPQFPAQEFPK
DKEQDLFDRIAKALEDSVEKHMRADVTVGSFLSGGIDSTAIATLAKRHNPNLLTFTTGFEREGYSEVDVAAESAAAIGVE
HIVKIVSPEEYANAIPQIMWYLDDPVADPSLVPLFFVAQEARKHVKVVLSGEGADELFGGYTIYKEPLSLAPFEKIPSPL
RRGLGKVAEVFPDGMRGKSLLQRGSMTMEERYYGNARSFNFDQMKRVIPWAKKEWDHREVTAPIYAQSEHMDPVARMQHL
DLFTWMRGDILVKADKINMAHSLELRVPFLDKEVFEVAETIPYDLKIANGTTKYALRKAMEQIVPPHVLHRKKLGFPVPM
RHWLAGDELFGWAQDTINESMTDQYFDKAAVLAMLNEHKNGVSDHSRRLWTVLAFMIWHGIFVEHRIDPGIEKRDYPVYL

Sequences:

>Translated_640_residues
MCGLLGMLSSTGQASKYAAAIESALPCMHHRGPDEAGTWHDDHAVFGFNRLSIIDLEHSHQPLRWGPEGEPDRYAMTFNG
EIYNYVELRKKLQDLGYTFNTSGDGETIAVGFHHWGADVVLHLRGMFGIAIWDTKEQRLFLARDQFGIKPLYFATTEAGT
VFASEKKCILGMADAIGLDLGLDQRAIEHYIDLQYVPEPESLHQHIRRLESGCFAFVSVGGNVEQTRYFRPQFPAQEFPK
DKEQDLFDRIAKALEDSVEKHMRADVTVGSFLSGGIDSTAIATLAKRHNPNLLTFTTGFEREGYSEVDVAAESAAAIGVE
HIVKIVSPEEYANAIPQIMWYLDDPVADPSLVPLFFVAQEARKHVKVVLSGEGADELFGGYTIYKEPLSLAPFEKIPSPL
RRGLGKVAEVFPDGMRGKSLLQRGSMTMEERYYGNARSFNFDQMKRVIPWAKKEWDHREVTAPIYAQSEHMDPVARMQHL
DLFTWMRGDILVKADKINMAHSLELRVPFLDKEVFEVAETIPYDLKIANGTTKYALRKAMEQIVPPHVLHRKKLGFPVPM
RHWLAGDELFGWAQDTINESMTDQYFDKAAVLAMLNEHKNGVSDHSRRLWTVLAFMIWHGIFVEHRIDPGIEKRDYPVYL
>Mature_640_residues
MCGLLGMLSSTGQASKYAAAIESALPCMHHRGPDEAGTWHDDHAVFGFNRLSIIDLEHSHQPLRWGPEGEPDRYAMTFNG
EIYNYVELRKKLQDLGYTFNTSGDGETIAVGFHHWGADVVLHLRGMFGIAIWDTKEQRLFLARDQFGIKPLYFATTEAGT
VFASEKKCILGMADAIGLDLGLDQRAIEHYIDLQYVPEPESLHQHIRRLESGCFAFVSVGGNVEQTRYFRPQFPAQEFPK
DKEQDLFDRIAKALEDSVEKHMRADVTVGSFLSGGIDSTAIATLAKRHNPNLLTFTTGFEREGYSEVDVAAESAAAIGVE
HIVKIVSPEEYANAIPQIMWYLDDPVADPSLVPLFFVAQEARKHVKVVLSGEGADELFGGYTIYKEPLSLAPFEKIPSPL
RRGLGKVAEVFPDGMRGKSLLQRGSMTMEERYYGNARSFNFDQMKRVIPWAKKEWDHREVTAPIYAQSEHMDPVARMQHL
DLFTWMRGDILVKADKINMAHSLELRVPFLDKEVFEVAETIPYDLKIANGTTKYALRKAMEQIVPPHVLHRKKLGFPVPM
RHWLAGDELFGWAQDTINESMTDQYFDKAAVLAMLNEHKNGVSDHSRRLWTVLAFMIWHGIFVEHRIDPGIEKRDYPVYL

Specific function: Asparagine biosynthesis. [C]

COG id: COG0367

COG function: function code E; Asparagine synthase (glutamine-hydrolyzing)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-2 domain [H]

Homologues:

Organism=Homo sapiens, GI168229248, Length=421, Percent_Identity=27.790973871734, Blast_Score=118, Evalue=2e-26,
Organism=Homo sapiens, GI168229252, Length=421, Percent_Identity=27.790973871734, Blast_Score=118, Evalue=2e-26,
Organism=Homo sapiens, GI168229250, Length=421, Percent_Identity=27.790973871734, Blast_Score=118, Evalue=2e-26,
Organism=Homo sapiens, GI296010848, Length=394, Percent_Identity=28.1725888324873, Blast_Score=115, Evalue=2e-25,
Organism=Homo sapiens, GI296010852, Length=325, Percent_Identity=27.3846153846154, Blast_Score=89, Evalue=1e-17,
Organism=Homo sapiens, GI296010850, Length=325, Percent_Identity=27.3846153846154, Blast_Score=89, Evalue=1e-17,
Organism=Escherichia coli, GI1786889, Length=402, Percent_Identity=27.363184079602, Blast_Score=148, Evalue=9e-37,
Organism=Caenorhabditis elegans, GI25147557, Length=408, Percent_Identity=29.1666666666667, Blast_Score=123, Evalue=3e-28,
Organism=Caenorhabditis elegans, GI71993933, Length=408, Percent_Identity=29.1666666666667, Blast_Score=123, Evalue=3e-28,
Organism=Caenorhabditis elegans, GI17560178, Length=401, Percent_Identity=26.9326683291771, Blast_Score=108, Evalue=6e-24,
Organism=Saccharomyces cerevisiae, GI6321563, Length=429, Percent_Identity=26.8065268065268, Blast_Score=130, Evalue=4e-31,
Organism=Saccharomyces cerevisiae, GI6325403, Length=432, Percent_Identity=26.8518518518519, Blast_Score=129, Evalue=1e-30,
Organism=Drosophila melanogaster, GI45553209, Length=417, Percent_Identity=27.5779376498801, Blast_Score=132, Evalue=9e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006426
- InterPro:   IPR001962
- InterPro:   IPR017932
- InterPro:   IPR014729 [H]

Pfam domain/function: PF00733 Asn_synthase [H]

EC number: =6.3.5.4 [H]

Molecular weight: Translated: 72517; Mature: 72517

Theoretical pI: Translated: 6.10; Mature: 6.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCGLLGMLSSTGQASKYAAAIESALPCMHHRGPDEAGTWHDDHAVFGFNRLSIIDLEHSH
CCCHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEECCCCEEEEEECCCC
QPLRWGPEGEPDRYAMTFNGEIYNYVELRKKLQDLGYTFNTSGDGETIAVGFHHWGADVV
CCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHCCCEEECCCCCCEEEEEEECCCHHHH
LHLRGMFGIAIWDTKEQRLFLARDQFGIKPLYFATTEAGTVFASEKKCILGMADAIGLDL
HHHHHHHEEEEECCCCCEEEEECCCCCCCEEEEEECCCCEEEECCCCEEEEEHHHHCCCC
GLDQRAIEHYIDLQYVPEPESLHQHIRRLESGCFAFVSVGGNVEQTRYFRPQFPAQEFPK
CCCHHHHHHHHCCEECCCHHHHHHHHHHHHCCCEEEEEECCCHHHCCCCCCCCCHHHCCC
DKEQDLFDRIAKALEDSVEKHMRADVTVGSFLSGGIDSTAIATLAKRHNPNLLTFTTGFE
CHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCHHHHHHHHHHCCCCEEEEECCCC
REGYSEVDVAAESAAAIGVEHIVKIVSPEEYANAIPQIMWYLDDPVADPSLVPLFFVAQE
CCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHH
ARKHVKVVLSGEGADELFGGYTIYKEPLSLAPFEKIPSPLRRGLGKVAEVFPDGMRGKSL
HHCCEEEEEECCCHHHHHCCEEEEECCCCCCCHHHCCHHHHHHHHHHHHHCCCCCCHHHH
LQRGSMTMEERYYGNARSFNFDQMKRVIPWAKKEWDHREVTAPIYAQSEHMDPVARMQHL
HHHCCCCHHHHHCCCCCCCCHHHHHHHCCCHHCCCCCCCCCCCEEECCCCCCHHHHHHHH
DLFTWMRGDILVKADKINMAHSLELRVPFLDKEVFEVAETIPYDLKIANGTTKYALRKAM
HHHHCCCCCEEEEEECCCCEEEEEEECCCCCHHHHHHHHHCCCEEEECCCCHHHHHHHHH
EQIVPPHVLHRKKLGFPVPMRHWLAGDELFGWAQDTINESMTDQYFDKAAVLAMLNEHKN
HHHCCHHHHHHHHCCCCCCHHHHHCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCC
GVSDHSRRLWTVLAFMIWHGIFVEHRIDPGIEKRDYPVYL
CCCHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCCCC
>Mature Secondary Structure
MCGLLGMLSSTGQASKYAAAIESALPCMHHRGPDEAGTWHDDHAVFGFNRLSIIDLEHSH
CCCHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEECCCCEEEEEECCCC
QPLRWGPEGEPDRYAMTFNGEIYNYVELRKKLQDLGYTFNTSGDGETIAVGFHHWGADVV
CCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHCCCEEECCCCCCEEEEEEECCCHHHH
LHLRGMFGIAIWDTKEQRLFLARDQFGIKPLYFATTEAGTVFASEKKCILGMADAIGLDL
HHHHHHHEEEEECCCCCEEEEECCCCCCCEEEEEECCCCEEEECCCCEEEEEHHHHCCCC
GLDQRAIEHYIDLQYVPEPESLHQHIRRLESGCFAFVSVGGNVEQTRYFRPQFPAQEFPK
CCCHHHHHHHHCCEECCCHHHHHHHHHHHHCCCEEEEEECCCHHHCCCCCCCCCHHHCCC
DKEQDLFDRIAKALEDSVEKHMRADVTVGSFLSGGIDSTAIATLAKRHNPNLLTFTTGFE
CHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCHHHHHHHHHHCCCCEEEEECCCC
REGYSEVDVAAESAAAIGVEHIVKIVSPEEYANAIPQIMWYLDDPVADPSLVPLFFVAQE
CCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHH
ARKHVKVVLSGEGADELFGGYTIYKEPLSLAPFEKIPSPLRRGLGKVAEVFPDGMRGKSL
HHCCEEEEEECCCHHHHHCCEEEEECCCCCCCHHHCCHHHHHHHHHHHHHCCCCCCHHHH
LQRGSMTMEERYYGNARSFNFDQMKRVIPWAKKEWDHREVTAPIYAQSEHMDPVARMQHL
HHHCCCCHHHHHCCCCCCCCHHHHHHHCCCHHCCCCCCCCCCCEEECCCCCCHHHHHHHH
DLFTWMRGDILVKADKINMAHSLELRVPFLDKEVFEVAETIPYDLKIANGTTKYALRKAM
HHHHCCCCCEEEEEECCCCEEEEEEECCCCCHHHHHHHHHCCCEEEECCCCHHHHHHHHH
EQIVPPHVLHRKKLGFPVPMRHWLAGDELFGWAQDTINESMTDQYFDKAAVLAMLNEHKN
HHHCCHHHHHHHHCCCCCCHHHHHCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCC
GVSDHSRRLWTVLAFMIWHGIFVEHRIDPGIEKRDYPVYL
CCCHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]