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The map label for this gene is pgsA2 [H]

Identifier: 38234039

GI number: 38234039

Start: 1475349

End: 1475939

Strand: Reverse

Name: pgsA2 [H]

Synonym: DIP1458

Alternate gene names: 38234039

Gene position: 1475939-1475349 (Counterclockwise)

Preceding gene: 38234041

Following gene: 38234038

Centisome position: 59.31

GC content: 45.69

Gene sequence:

>591_bases
GTGAGTGTGAAACAGGAGCGCGAAAATACGTCAGAGCACAGCACACCATCTAATTGGAACGTTCCTAATGTGCTAACGAG
TTTGAGAATCATTGTGATTCCGTTGTTTGCATGGTTTGTTCTTCAAAGTGATGGTCACATCACGCGATGGTTATGGTGGG
CTTTTGGAACCTTTGTGGCGTTGATGATCACTGACAAGCTTGATGGTGATATTGCACGCGCCAAAAATCTGGTCACAAAT
TTTGGGAAAATTGCGGATCCGATTGCCGATAAAGCCCTGATGATTACCGCTTTAGTCACTCTCAATATCATTGGTTTAGT
ACCGTGGTGGATAACGATTGTCATCGTCGTACGTGAGCTCGGTATTACTTTGTGGCGTTTCTTTGAGCTCAAGAAAGGCA
ACGTGGTGCCGGCAAGTAAGGGGGGTAAAATTAAGACCACTTTGCAGGCTTTTGCCGTGGCACTCTATCTCTTGCCGTTG
CCTGATGCGGTGCAGCCGATTCAGTTCTTTGTAATGCTGTGTGCGGTTGTGGTGACTGTCGTAACGGGAGTTCAATATCT
AATCGATGCTAAGAAGCTAAAAAATGCTTGA

Upstream 100 bases:

>100_bases
GTCATAGCGAACATGGTAGTAGGCAGAGAAGAAAAAGGGGGAGAGTACTCCGAAGACGATGTGTGGTAGTACATAAGATT
TTGTTTTGAGGGTAGTGTGA

Downstream 100 bases:

>100_bases
CGACGCCACCCAAGCTGCTGTCACCCGTATGGTCGATAAATTAAAACAGCAGAATTGCACGATCTCTACGTGCGAATCGC
TTACTGCTGGGCTTATGGCG

Product: putative phosphatidyltransferase

Products: NA

Alternate protein names: Phosphatidylglycerophosphate synthase; PGP synthase [H]

Number of amino acids: Translated: 196; Mature: 195

Protein sequence:

>196_residues
MSVKQERENTSEHSTPSNWNVPNVLTSLRIIVIPLFAWFVLQSDGHITRWLWWAFGTFVALMITDKLDGDIARAKNLVTN
FGKIADPIADKALMITALVTLNIIGLVPWWITIVIVVRELGITLWRFFELKKGNVVPASKGGKIKTTLQAFAVALYLLPL
PDAVQPIQFFVMLCAVVVTVVTGVQYLIDAKKLKNA

Sequences:

>Translated_196_residues
MSVKQERENTSEHSTPSNWNVPNVLTSLRIIVIPLFAWFVLQSDGHITRWLWWAFGTFVALMITDKLDGDIARAKNLVTN
FGKIADPIADKALMITALVTLNIIGLVPWWITIVIVVRELGITLWRFFELKKGNVVPASKGGKIKTTLQAFAVALYLLPL
PDAVQPIQFFVMLCAVVVTVVTGVQYLIDAKKLKNA
>Mature_195_residues
SVKQERENTSEHSTPSNWNVPNVLTSLRIIVIPLFAWFVLQSDGHITRWLWWAFGTFVALMITDKLDGDIARAKNLVTNF
GKIADPIADKALMITALVTLNIIGLVPWWITIVIVVRELGITLWRFFELKKGNVVPASKGGKIKTTLQAFAVALYLLPLP
DAVQPIQFFVMLCAVVVTVVTGVQYLIDAKKLKNA

Specific function: This Protein Catalyzes The Committed Step To The Synthesis Of The Acidic Phospholipids. [C]

COG id: COG0558

COG function: function code I; Phosphatidylglycerophosphate synthase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CDP-alcohol phosphatidyltransferase class-I family [H]

Homologues:

Organism=Escherichia coli, GI1788220, Length=181, Percent_Identity=35.9116022099448, Blast_Score=70, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000462
- InterPro:   IPR004570 [H]

Pfam domain/function: PF01066 CDP-OH_P_transf [H]

EC number: =2.7.8.5 [H]

Molecular weight: Translated: 21872; Mature: 21741

Theoretical pI: Translated: 10.25; Mature: 10.25

Prosite motif: PS00379 CDP_ALCOHOL_P_TRANSF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVKQERENTSEHSTPSNWNVPNVLTSLRIIVIPLFAWFVLQSDGHITRWLWWAFGTFVA
CCCCHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
LMITDKLDGDIARAKNLVTNFGKIADPIADKALMITALVTLNIIGLVPWWITIVIVVREL
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GITLWRFFELKKGNVVPASKGGKIKTTLQAFAVALYLLPLPDAVQPIQFFVMLCAVVVTV
HHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
VTGVQYLIDAKKLKNA
HHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SVKQERENTSEHSTPSNWNVPNVLTSLRIIVIPLFAWFVLQSDGHITRWLWWAFGTFVA
CCCHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
LMITDKLDGDIARAKNLVTNFGKIADPIADKALMITALVTLNIIGLVPWWITIVIVVREL
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GITLWRFFELKKGNVVPASKGGKIKTTLQAFAVALYLLPLPDAVQPIQFFVMLCAVVVTV
HHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
VTGVQYLIDAKKLKNA
HHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9634230; 12368430; 12218036; 10889206 [H]