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The map label for this gene is rutG [H]

Identifier: 38234019

GI number: 38234019

Start: 1456969

End: 1458255

Strand: Reverse

Name: rutG [H]

Synonym: DIP1438

Alternate gene names: 38234019

Gene position: 1458255-1456969 (Counterclockwise)

Preceding gene: 38234020

Following gene: 38234013

Centisome position: 58.6

GC content: 48.64

Gene sequence:

>1287_bases
GTGAGTACAGCATCTTGGGGTTGGACCCTACACGGAGATGGCAAGACCATCGCACCAGGCGCAGTTGTTGCACCTGAAGA
ACGGCTCAGTTGGAGCCGAACCATCGGCATTGGAATGCAACATGTGATCGCTATGTTTGGCGCTACATTGTTGGTTCCAA
CTCTCACTGGATTTCCTGTCAACACCACCTTGCTATTCTCCGGAATTAGCACGATGGTGTTTCTTCTTATTACGAGAAAT
CGTCTTCCTTCGTATCTGGGAAGTTCCTTTGGATTCATCGCACCTTTGATGGCTTCTCAAGGAGAAGGGATTGGCGTACA
ACTCGGTGGCGTTGTTGCGACTGGCCTTGCCTTAATTCTAGTGGGCTTTATTGTTAAATCCGCAGGCCGGAAAGTAATTG
ATTTGGTTATGCCGCCTGCAGTAACTGGCGCCATTGTTGCCCTGATCGGCCTCAACTTAGCTCCAAGCGCTGCTGGAAAC
TTTCAATCGCAGCCCTTAGTTGCAGTTGTAACACTAGCGAGCATTTTGCTTTTTACGGTTGCCGGACGTGGGATGGTTGC
TCGCCTAGGCATTCTTATTGGTGTAATTATTGGTTGGGTTTTTGCCGCTATAACCGGCAACCTTGCTGAAGGCGCGAGTG
ATAGTGTTCGGGAGGCGGCTTGGATTGGTTTCCCACAATTTCATACGCCAGAATTCACAACACACGCTATTTTAGTAACG
CTGCCAGTTGTTATTGTTTTGATTGCTGAAAACGTTGGACATGTTAAAGCTGTGAGCGAAATGACGGGGCGTAACCTCGA
TGATTTAGCTGGTGATGCTTTGATTGCAGACGGTATCGGAACAACCTTTGCCGGTGCATTCGGTGGCTCAGGAACTACGA
CATATGCCGAAAATATCGGTGTCATGGCGGCTACGAAAGTCTATTCCACAGCGGCCTACTGGGTAGCAGCGCTTACAGCT
GTGGTGCTTGCGTTCATTCCAAAATTTGGAGCCCTAATTTTTACTATTCCAACTGGAGTTCTTGGTGGCGCTGCATTAGT
TCTTTACGGATTGATCGGCATGCTCGGTGTTCGTATCTGGCAAGACAATAAGGTTAACTTCAATAACCCAGTTAACCTCA
CAGCAGCAGCCGTGGCGCTTATCGCCGGTATCGGTAACCTCACCTTAGTGATCGGTGGGATTGAGCTTCAAGGAATCGCG
TGGGGTTCAATGGGTATTATCGTTTTCTATCCTGTACTCAAGTGGTTGTATCTTCGTGTGGGCGAAGGAAACAACGCACG
TTTCTAA

Upstream 100 bases:

>100_bases
GAGCTACGAGTTGATTAAGCACCTGACTTCATCTGCAATGGGGTAGACCCATGATGTTGTATTTGTTTTATTCCTTGTGT
GGGAGCCATAATGAGGTTTC

Downstream 100 bases:

>100_bases
TAAAAATTGTGCCCGAAAACCTGAGAGGTTTTTCGGGCACAATTTTGCTATTTACGTGTATTTAACCGCTGTGGCCCTTA
AGCATATCTTCAAAATTAGT

Product: putative transport membrane protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 428; Mature: 427

Protein sequence:

>428_residues
MSTASWGWTLHGDGKTIAPGAVVAPEERLSWSRTIGIGMQHVIAMFGATLLVPTLTGFPVNTTLLFSGISTMVFLLITRN
RLPSYLGSSFGFIAPLMASQGEGIGVQLGGVVATGLALILVGFIVKSAGRKVIDLVMPPAVTGAIVALIGLNLAPSAAGN
FQSQPLVAVVTLASILLFTVAGRGMVARLGILIGVIIGWVFAAITGNLAEGASDSVREAAWIGFPQFHTPEFTTHAILVT
LPVVIVLIAENVGHVKAVSEMTGRNLDDLAGDALIADGIGTTFAGAFGGSGTTTYAENIGVMAATKVYSTAAYWVAALTA
VVLAFIPKFGALIFTIPTGVLGGAALVLYGLIGMLGVRIWQDNKVNFNNPVNLTAAAVALIAGIGNLTLVIGGIELQGIA
WGSMGIIVFYPVLKWLYLRVGEGNNARF

Sequences:

>Translated_428_residues
MSTASWGWTLHGDGKTIAPGAVVAPEERLSWSRTIGIGMQHVIAMFGATLLVPTLTGFPVNTTLLFSGISTMVFLLITRN
RLPSYLGSSFGFIAPLMASQGEGIGVQLGGVVATGLALILVGFIVKSAGRKVIDLVMPPAVTGAIVALIGLNLAPSAAGN
FQSQPLVAVVTLASILLFTVAGRGMVARLGILIGVIIGWVFAAITGNLAEGASDSVREAAWIGFPQFHTPEFTTHAILVT
LPVVIVLIAENVGHVKAVSEMTGRNLDDLAGDALIADGIGTTFAGAFGGSGTTTYAENIGVMAATKVYSTAAYWVAALTA
VVLAFIPKFGALIFTIPTGVLGGAALVLYGLIGMLGVRIWQDNKVNFNNPVNLTAAAVALIAGIGNLTLVIGGIELQGIA
WGSMGIIVFYPVLKWLYLRVGEGNNARF
>Mature_427_residues
STASWGWTLHGDGKTIAPGAVVAPEERLSWSRTIGIGMQHVIAMFGATLLVPTLTGFPVNTTLLFSGISTMVFLLITRNR
LPSYLGSSFGFIAPLMASQGEGIGVQLGGVVATGLALILVGFIVKSAGRKVIDLVMPPAVTGAIVALIGLNLAPSAAGNF
QSQPLVAVVTLASILLFTVAGRGMVARLGILIGVIIGWVFAAITGNLAEGASDSVREAAWIGFPQFHTPEFTTHAILVTL
PVVIVLIAENVGHVKAVSEMTGRNLDDLAGDALIADGIGTTFAGAFGGSGTTTYAENIGVMAATKVYSTAAYWVAALTAV
VLAFIPKFGALIFTIPTGVLGGAALVLYGLIGMLGVRIWQDNKVNFNNPVNLTAAAVALIAGIGNLTLVIGGIELQGIAW
GSMGIIVFYPVLKWLYLRVGEGNNARF

Specific function: May function as a proton-driven pyrimidine uptake system [H]

COG id: COG2233

COG function: function code F; Xanthine/uracil permeases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xanthine/uracil permease family. Nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) subfamily [H]

Homologues:

Organism=Escherichia coli, GI87081818, Length=421, Percent_Identity=44.8931116389549, Blast_Score=327, Evalue=7e-91,
Organism=Escherichia coli, GI1788843, Length=397, Percent_Identity=40.8060453400504, Blast_Score=255, Evalue=4e-69,
Organism=Escherichia coli, GI87082181, Length=391, Percent_Identity=27.3657289002558, Blast_Score=112, Evalue=4e-26,
Organism=Escherichia coli, GI1790087, Length=383, Percent_Identity=26.3707571801567, Blast_Score=75, Evalue=7e-15,
Organism=Escherichia coli, GI87082178, Length=240, Percent_Identity=28.3333333333333, Blast_Score=64, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17541904, Length=226, Percent_Identity=26.9911504424779, Blast_Score=69, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17558856, Length=170, Percent_Identity=30, Blast_Score=66, Evalue=4e-11,
Organism=Drosophila melanogaster, GI21356175, Length=423, Percent_Identity=24.822695035461, Blast_Score=75, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019918
- InterPro:   IPR006042
- InterPro:   IPR006043 [H]

Pfam domain/function: PF00860 Xan_ur_permease [H]

EC number: NA

Molecular weight: Translated: 44216; Mature: 44084

Theoretical pI: Translated: 8.79; Mature: 8.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTASWGWTLHGDGKTIAPGAVVAPEERLSWSRTIGIGMQHVIAMFGATLLVPTLTGFPV
CCCCCCCEEEECCCCEECCCCEECCHHHHCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
NTTLLFSGISTMVFLLITRNRLPSYLGSSFGFIAPLMASQGEGIGVQLGGVVATGLALIL
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCEEEEHHHHHHHHHHHH
VGFIVKSAGRKVIDLVMPPAVTGAIVALIGLNLAPSAAGNFQSQPLVAVVTLASILLFTV
HHHHHHHCCCCEEHHHCCCHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
AGRGMVARLGILIGVIIGWVFAAITGNLAEGASDSVREAAWIGFPQFHTPEFTTHAILVT
CCCCHHHHHHHHHHHHHHHHHHHHHCCHHCCCCHHHHHHHHCCCCCCCCCCHHHHHHHHH
LPVVIVLIAENVGHVKAVSEMTGRNLDDLAGDALIADGIGTTFAGAFGGSGTTTYAENIG
HHHHHHHHHCCCCHHHHHHHHHCCCHHHHCCCEEEECCCCHHHHHCCCCCCCCHHHHCCC
VMAATKVYSTAAYWVAALTAVVLAFIPKFGALIFTIPTGVLGGAALVLYGLIGMLGVRIW
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECHHHHHHHHHHHHHHHHHHHEEEE
QDNKVNFNNPVNLTAAAVALIAGIGNLTLVIGGIELQGIAWGSMGIIVFYPVLKWLYLRV
CCCCCCCCCCCHHHHHHHHHHHCCCCEEEEEECEEEEEEEECCCHHHHHHHHHHHHHEEE
GEGNNARF
CCCCCCCC
>Mature Secondary Structure 
STASWGWTLHGDGKTIAPGAVVAPEERLSWSRTIGIGMQHVIAMFGATLLVPTLTGFPV
CCCCCCEEEECCCCEECCCCEECCHHHHCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
NTTLLFSGISTMVFLLITRNRLPSYLGSSFGFIAPLMASQGEGIGVQLGGVVATGLALIL
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCEEEEHHHHHHHHHHHH
VGFIVKSAGRKVIDLVMPPAVTGAIVALIGLNLAPSAAGNFQSQPLVAVVTLASILLFTV
HHHHHHHCCCCEEHHHCCCHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
AGRGMVARLGILIGVIIGWVFAAITGNLAEGASDSVREAAWIGFPQFHTPEFTTHAILVT
CCCCHHHHHHHHHHHHHHHHHHHHHCCHHCCCCHHHHHHHHCCCCCCCCCCHHHHHHHHH
LPVVIVLIAENVGHVKAVSEMTGRNLDDLAGDALIADGIGTTFAGAFGGSGTTTYAENIG
HHHHHHHHHCCCCHHHHHHHHHCCCHHHHCCCEEEECCCCHHHHHCCCCCCCCHHHHCCC
VMAATKVYSTAAYWVAALTAVVLAFIPKFGALIFTIPTGVLGGAALVLYGLIGMLGVRIW
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECHHHHHHHHHHHHHHHHHHHEEEE
QDNKVNFNNPVNLTAAAVALIAGIGNLTLVIGGIELQGIAWGSMGIIVFYPVLKWLYLRV
CCCCCCCCCCCHHHHHHHHHHHCCCCEEEEEECEEEEEEEECCCHHHHHHHHHHHHHEEE
GEGNNARF
CCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503 [H]