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The map label for this gene is secF [H]

Identifier: 38233956

GI number: 38233956

Start: 1389519

End: 1390631

Strand: Reverse

Name: secF [H]

Synonym: DIP1371

Alternate gene names: 38233956

Gene position: 1390631-1389519 (Counterclockwise)

Preceding gene: 38233957

Following gene: 38233955

Centisome position: 55.88

GC content: 47.35

Gene sequence:

>1113_bases
ATGAGTGGCAATAGCGTTTTGTCAAAGCTCTACACCGGTGATGGTGGACTAGACTTCGTTGGACGCCGTCGAACGTGGTA
CCGAACCACACTTATCATTGTGGCGATTTGTTTCATTGCGATAGCCGTTCGCGGTTTTAGTCTTGGAATTGATTTTGTTG
GTGGCACCAAGATGAATATGCCGGCAGCACAATTGGAAACTTCAGAAGTTGCTGACACATTCAAAGATGCCACAGGTATC
GAACCAGAGTTGGTTCAAATTGTGGGATCTGGTGATACGCGTATCTTGGAAATCAACTCTGAGCGACTAAGCGAAGATCA
AATTTCTCAAGCTCGTGTAGCACTTTTTGAGAAATATCAGCCTGTGGGGTCCCAAGGTCAACCAACGCCAGACGCTATCG
GTGATTCTACGGTATCGGAATCCTGGGGATCTACGATTACCCAGCGCATGCTGATCTCGATGTTTGTATTCCTAGCGGCA
GTTTTTGTCTACATTACGGTTCGCTTGGAAAAAGAAATGGCAGTAGCCGCAATTGTTGCGTTGCTCGTAGATTTGATTGT
TATTTCTGGCGTTTATGCTCTAGTTGGCTTCGAAGTTTCTCCTGCGACTATTATCGGTCTTCTTACCGTCCTAGCTTTCT
CGTTGTATGACACAGTCATCGTGTTTGACAAGGTGCGCGAAAATACAGCTGGATATTTGGGTAATCGCACTCGCACCTAT
GCGGAACACGCAAACCTAGCTGTTAATCAAACGGTGATGCGTTCAATCTCGACGACGATTATCTCAGCACTTCCAATTAT
TGCTTTGATTGTTATCGCTGTGTGGCTCATGGGAGTCGGTACCCTGAAAGACTTGGCTCTTGTCCAGCTCATTGGTGTTA
TTGAAGGTACTTTCTCGTCCGTATTCCTTGCCACTCCAATCTTGGTGTCATTAAAGAATCGCTCTAAGAAGACCGCCGAG
CATAACCGACAAGTAGAAATGCACCGATGCGGTGCAGAAGCTCAAGATGACTCTGCCCCTGAGCAATCTGCTGAATCTAC
GCAGAAGCGTACGGTGTCTGGCCCACAGGTTACAACGTCGACAGGTGCAAGTTGGCGTCCTGACCGAGGGTAA

Upstream 100 bases:

>100_bases
CGCATCTCGAAAGCCGTGGACATCTTCAGGTGCAGCAAATGGCATGGGAAAAATTATTTCTATGCATCACGGTGCCAACG
CAGCCAAAGGAGAAGAATAA

Downstream 100 bases:

>100_bases
CTACACATTATTGATTGAAAATTCCCCCTGAATTGAACTAACTTCTTTCAATTCAGGGGGAATTTTCATATGGGGTGCGG
CCAACTAGATAGGGTGGATT

Product: preprotein translocase subunit SecF

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 370; Mature: 369

Protein sequence:

>370_residues
MSGNSVLSKLYTGDGGLDFVGRRRTWYRTTLIIVAICFIAIAVRGFSLGIDFVGGTKMNMPAAQLETSEVADTFKDATGI
EPELVQIVGSGDTRILEINSERLSEDQISQARVALFEKYQPVGSQGQPTPDAIGDSTVSESWGSTITQRMLISMFVFLAA
VFVYITVRLEKEMAVAAIVALLVDLIVISGVYALVGFEVSPATIIGLLTVLAFSLYDTVIVFDKVRENTAGYLGNRTRTY
AEHANLAVNQTVMRSISTTIISALPIIALIVIAVWLMGVGTLKDLALVQLIGVIEGTFSSVFLATPILVSLKNRSKKTAE
HNRQVEMHRCGAEAQDDSAPEQSAESTQKRTVSGPQVTTSTGASWRPDRG

Sequences:

>Translated_370_residues
MSGNSVLSKLYTGDGGLDFVGRRRTWYRTTLIIVAICFIAIAVRGFSLGIDFVGGTKMNMPAAQLETSEVADTFKDATGI
EPELVQIVGSGDTRILEINSERLSEDQISQARVALFEKYQPVGSQGQPTPDAIGDSTVSESWGSTITQRMLISMFVFLAA
VFVYITVRLEKEMAVAAIVALLVDLIVISGVYALVGFEVSPATIIGLLTVLAFSLYDTVIVFDKVRENTAGYLGNRTRTY
AEHANLAVNQTVMRSISTTIISALPIIALIVIAVWLMGVGTLKDLALVQLIGVIEGTFSSVFLATPILVSLKNRSKKTAE
HNRQVEMHRCGAEAQDDSAPEQSAESTQKRTVSGPQVTTSTGASWRPDRG
>Mature_369_residues
SGNSVLSKLYTGDGGLDFVGRRRTWYRTTLIIVAICFIAIAVRGFSLGIDFVGGTKMNMPAAQLETSEVADTFKDATGIE
PELVQIVGSGDTRILEINSERLSEDQISQARVALFEKYQPVGSQGQPTPDAIGDSTVSESWGSTITQRMLISMFVFLAAV
FVYITVRLEKEMAVAAIVALLVDLIVISGVYALVGFEVSPATIIGLLTVLAFSLYDTVIVFDKVRENTAGYLGNRTRTYA
EHANLAVNQTVMRSISTTIISALPIIALIVIAVWLMGVGTLKDLALVQLIGVIEGTFSSVFLATPILVSLKNRSKKTAEH
NRQVEMHRCGAEAQDDSAPEQSAESTQKRTVSGPQVTTSTGASWRPDRG

Specific function: Involved in protein export [H]

COG id: COG0341

COG function: function code U; Preprotein translocase subunit SecF

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the secD/secF family. SecF subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786610, Length=318, Percent_Identity=28.6163522012579, Blast_Score=96, Evalue=4e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022813
- InterPro:   IPR022646
- InterPro:   IPR022645
- InterPro:   IPR005665 [H]

Pfam domain/function: PF07549 Sec_GG; PF02355 SecD_SecF [H]

EC number: NA

Molecular weight: Translated: 39917; Mature: 39786

Theoretical pI: Translated: 5.22; Mature: 5.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGNSVLSKLYTGDGGLDFVGRRRTWYRTTLIIVAICFIAIAVRGFSLGIDFVGGTKMNM
CCCHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCC
PAAQLETSEVADTFKDATGIEPELVQIVGSGDTRILEINSERLSEDQISQARVALFEKYQ
CHHHHHHHHHHHHHHHCCCCCHHHHHEECCCCEEEEEECHHHCCHHHHHHHHHHHHHHHC
PVGSQGQPTPDAIGDSTVSESWGSTITQRMLISMFVFLAAVFVYITVRLEKEMAVAAIVA
CCCCCCCCCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLVDLIVISGVYALVGFEVSPATIIGLLTVLAFSLYDTVIVFDKVRENTAGYLGNRTRTY
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
AEHANLAVNQTVMRSISTTIISALPIIALIVIAVWLMGVGTLKDLALVQLIGVIEGTFSS
HHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
VFLATPILVSLKNRSKKTAEHNRQVEMHRCGAEAQDDSAPEQSAESTQKRTVSGPQVTTS
HHHHHHHHHHHHHCCHHHHHHHCCHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCCCEECC
TGASWRPDRG
CCCCCCCCCC
>Mature Secondary Structure 
SGNSVLSKLYTGDGGLDFVGRRRTWYRTTLIIVAICFIAIAVRGFSLGIDFVGGTKMNM
CCHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCC
PAAQLETSEVADTFKDATGIEPELVQIVGSGDTRILEINSERLSEDQISQARVALFEKYQ
CHHHHHHHHHHHHHHHCCCCCHHHHHEECCCCEEEEEECHHHCCHHHHHHHHHHHHHHHC
PVGSQGQPTPDAIGDSTVSESWGSTITQRMLISMFVFLAAVFVYITVRLEKEMAVAAIVA
CCCCCCCCCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLVDLIVISGVYALVGFEVSPATIIGLLTVLAFSLYDTVIVFDKVRENTAGYLGNRTRTY
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
AEHANLAVNQTVMRSISTTIISALPIIALIVIAVWLMGVGTLKDLALVQLIGVIEGTFSS
HHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
VFLATPILVSLKNRSKKTAEHNRQVEMHRCGAEAQDDSAPEQSAESTQKRTVSGPQVTTS
HHHHHHHHHHHHHCCHHHHHHHCCHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCCCEECC
TGASWRPDRG
CCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]