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The map label for this gene is corA [H]

Identifier: 38233805

GI number: 38233805

Start: 1216886

End: 1217986

Strand: Reverse

Name: corA [H]

Synonym: DIP1215

Alternate gene names: 38233805

Gene position: 1217986-1216886 (Counterclockwise)

Preceding gene: 38233807

Following gene: 38233803

Centisome position: 48.94

GC content: 46.5

Gene sequence:

>1101_bases
ATGAACGAAAAGAATCGCCAGCTACCAGCATTCACCCCGCGAAATCGCCGCACGCACCCCATAAGCGCTGAGCGTAAGCA
ACTTGGTGTTGACGATATTGTTGATCACTGCATGATTTATGTTGATGGACGAGCAATTCAAGGGTGGTTCGATTACGGAT
CCGGCTTAAAACGCGTGAAGGACTTCATTGCTTCGGGCCATAAAGCTTTCATGTGGTTATCTCTCGAAGAACCCAGCGAA
CAACACATGATGCAGGTTGCCGATGATCTCCACATCCACGAACTCATCGTCGAAGACGCTGTAACTGCACATCAGAGGCC
TAAAGTCGAACGCTACGACGATCAAATCTTCATGGTGGTTCGATCAGTTTTCTACCGTGATCACGAAACGGTTGATGACG
CAAACGAAATTATTAAAACCGGTGAAGTTCAAATGCTGATTGGCGAACACTTCATCATCACAATCCGACACCGTACCCCT
ATGCCTGATTTAACGATGCGTCTCGACGACCCACAAGAAATCAGCAGCTATGGGCCGATGATCATAGCTTGGGCGTGGGC
AGATTATCTTGTCGACGGATACCTGCGTATCGTCAATATACTTGCCGAAGAAGTTGATGAGCTTGAAGAAGAAGTATTTA
CCCCAGGTAGCAGCTTCAACATCGAGCACATCTACATGATTAAACGCGAAATTTTAGAAATGCGACACGCCATTGATCCG
TTAGCTCCCGCTTTACGCATGCTCGTTACACAGCATAAGGATATGATCGCGAAACAACTCCGGTCGTATCTGCGAGATGT
CCTTGACCATGAAATGGTAGCCAAGGACTATGTGGCAAACTTTGACGAACGTCTTAGTTCCCTAATCGACGCTGGCGTGG
CAAAGATTTCACTACAGCAAAACTCTGATATGCGCGCTATATCTGCCTATGTTGGTATGGCAGCGGTTCCTACACTTATC
GCCGGAATTTACGGAATGAATTTTGAAAATATGCCGGAACTAGCTACCAACTACGGCTACTACATTGTAATTCTTGTCAT
GGTACTAACCGTGAGTCTCATGTGGTGGTACTTCCGCAAGATGAATTGGATTGGAAACTAA

Upstream 100 bases:

>100_bases
AGTTATGTGAATGCTGGGGGTTTCGTACTTTGATGTCGTTCCAAGTTGGCATACGTTCAATAATAGACACTAAAACACAA
AAAGAGGTCTGCATAAAGCT

Downstream 100 bases:

>100_bases
GCCATTTTATCTTTCTGGCGCTTTTCTGGTTGCGGAGCTACCAACAAAGTACGAAGTGTTGCTCGCGCCACTAGCTTGCC
CCTGTGGTGCATGTCAACGG

Product: magnesium/cobalt transporter CorA

Products: Ni2; [Cytoplasm]; Co; 2 [Cytoplasm]; Mg (II) [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 366; Mature: 366

Protein sequence:

>366_residues
MNEKNRQLPAFTPRNRRTHPISAERKQLGVDDIVDHCMIYVDGRAIQGWFDYGSGLKRVKDFIASGHKAFMWLSLEEPSE
QHMMQVADDLHIHELIVEDAVTAHQRPKVERYDDQIFMVVRSVFYRDHETVDDANEIIKTGEVQMLIGEHFIITIRHRTP
MPDLTMRLDDPQEISSYGPMIIAWAWADYLVDGYLRIVNILAEEVDELEEEVFTPGSSFNIEHIYMIKREILEMRHAIDP
LAPALRMLVTQHKDMIAKQLRSYLRDVLDHEMVAKDYVANFDERLSSLIDAGVAKISLQQNSDMRAISAYVGMAAVPTLI
AGIYGMNFENMPELATNYGYYIVILVMVLTVSLMWWYFRKMNWIGN

Sequences:

>Translated_366_residues
MNEKNRQLPAFTPRNRRTHPISAERKQLGVDDIVDHCMIYVDGRAIQGWFDYGSGLKRVKDFIASGHKAFMWLSLEEPSE
QHMMQVADDLHIHELIVEDAVTAHQRPKVERYDDQIFMVVRSVFYRDHETVDDANEIIKTGEVQMLIGEHFIITIRHRTP
MPDLTMRLDDPQEISSYGPMIIAWAWADYLVDGYLRIVNILAEEVDELEEEVFTPGSSFNIEHIYMIKREILEMRHAIDP
LAPALRMLVTQHKDMIAKQLRSYLRDVLDHEMVAKDYVANFDERLSSLIDAGVAKISLQQNSDMRAISAYVGMAAVPTLI
AGIYGMNFENMPELATNYGYYIVILVMVLTVSLMWWYFRKMNWIGN
>Mature_366_residues
MNEKNRQLPAFTPRNRRTHPISAERKQLGVDDIVDHCMIYVDGRAIQGWFDYGSGLKRVKDFIASGHKAFMWLSLEEPSE
QHMMQVADDLHIHELIVEDAVTAHQRPKVERYDDQIFMVVRSVFYRDHETVDDANEIIKTGEVQMLIGEHFIITIRHRTP
MPDLTMRLDDPQEISSYGPMIIAWAWADYLVDGYLRIVNILAEEVDELEEEVFTPGSSFNIEHIYMIKREILEMRHAIDP
LAPALRMLVTQHKDMIAKQLRSYLRDVLDHEMVAKDYVANFDERLSSLIDAGVAKISLQQNSDMRAISAYVGMAAVPTLI
AGIYGMNFENMPELATNYGYYIVILVMVLTVSLMWWYFRKMNWIGN

Specific function: Mediates influx of magnesium ions [H]

COG id: COG0598

COG function: function code P; Mg2+ and Co2+ transporters

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family [H]

Homologues:

Organism=Escherichia coli, GI2367297, Length=107, Percent_Identity=33.6448598130841, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004488
- InterPro:   IPR002523 [H]

Pfam domain/function: PF01544 CorA [H]

EC number: NA

Molecular weight: Translated: 42430; Mature: 42430

Theoretical pI: Translated: 5.05; Mature: 5.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
6.0 %Met     (Translated Protein)
6.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
6.0 %Met     (Mature Protein)
6.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNEKNRQLPAFTPRNRRTHPISAERKQLGVDDIVDHCMIYVDGRAIQGWFDYGSGLKRVK
CCCCCCCCCCCCCCCCCCCCCCHHHHHCCHHHHHHHHEEEECCCEEEHHHHHCHHHHHHH
DFIASGHKAFMWLSLEEPSEQHMMQVADDLHIHELIVEDAVTAHQRPKVERYDDQIFMVV
HHHHCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
RSVFYRDHETVDDANEIIKTGEVQMLIGEHFIITIRHRTPMPDLTMRLDDPQEISSYGPM
HHHHHHCCCCHHHHHHHHHCCCEEEEECCEEEEEEECCCCCCCCEEECCCHHHHHHCCCE
IIAWAWADYLVDGYLRIVNILAEEVDELEEEVFTPGSSFNIEHIYMIKREILEMRHAIDP
EEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCH
LAPALRMLVTQHKDMIAKQLRSYLRDVLDHEMVAKDYVANFDERLSSLIDAGVAKISLQQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECC
NSDMRAISAYVGMAAVPTLIAGIYGMNFENMPELATNYGYYIVILVMVLTVSLMWWYFRK
CCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
MNWIGN
HHHCCC
>Mature Secondary Structure
MNEKNRQLPAFTPRNRRTHPISAERKQLGVDDIVDHCMIYVDGRAIQGWFDYGSGLKRVK
CCCCCCCCCCCCCCCCCCCCCCHHHHHCCHHHHHHHHEEEECCCEEEHHHHHCHHHHHHH
DFIASGHKAFMWLSLEEPSEQHMMQVADDLHIHELIVEDAVTAHQRPKVERYDDQIFMVV
HHHHCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
RSVFYRDHETVDDANEIIKTGEVQMLIGEHFIITIRHRTPMPDLTMRLDDPQEISSYGPM
HHHHHHCCCCHHHHHHHHHCCCEEEEECCEEEEEEECCCCCCCCEEECCCHHHHHHCCCE
IIAWAWADYLVDGYLRIVNILAEEVDELEEEVFTPGSSFNIEHIYMIKREILEMRHAIDP
EEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCH
LAPALRMLVTQHKDMIAKQLRSYLRDVLDHEMVAKDYVANFDERLSSLIDAGVAKISLQQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECC
NSDMRAISAYVGMAAVPTLIAGIYGMNFENMPELATNYGYYIVILVMVLTVSLMWWYFRK
CCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
MNWIGN
HHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Ni2; [Periplasm]; Co; 2 [Periplasm]; Mg (II) [Periplasm] [C]

Specific reaction: Ni2+ [Periplasm] = Ni2+ [Cytoplasm] Co+2 [Periplasm] = Co+2 [Cytoplasm] Mg (II) [Periplasm] = Mg (II) [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]