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The map label for this gene is dcuD [H]

Identifier: 38233739

GI number: 38233739

Start: 1135099

End: 1136511

Strand: Reverse

Name: dcuD [H]

Synonym: DIP1149

Alternate gene names: 38233739

Gene position: 1136511-1135099 (Counterclockwise)

Preceding gene: 38233740

Following gene: 38233737

Centisome position: 45.67

GC content: 49.26

Gene sequence:

>1413_bases
GTGCTTTATCTTCTCATAGCCCTCATTTCCTTCGCCGCAGTGATGTACCTAATTATCAAGAAAGTCAACGCTGCTGCTGC
GATTTTCTTCGTGGGTGTACTTCTTCTTATGATTGCGGCTATTTCTGGGAAGGCCGAACCGTCAGTAGAAATTAAACCAT
CTGGTAATAGTTTTTACGATGAGCTGCTTGTCATCGAGGCACTTTTTAAATCCAGATTTTCTGGTATTGGCATGGCCATC
ATGGTGCTCTTTGGTTTTGTCTCCTACATGCGCACAATCGGTGCCGACGCCAAAGCAGTCGTTCTTTTGTCCGCACCACT
CCAAAAAATGCGCGGTTCTTACTGGATGGTACCGATCGGTTTTACCATTGGAACTGCGTTGTCCCTGATTGTGCCATCAG
CGTCCGCACTTTCTCTGCTATTGGTCGCTACCCTATTACCAGCACTCGTCGCAGCCGGTCTCACCCCACTCACCGTGGCC
GCTATCATCGTCACCTCATCAACCATCGTAGCTACACCTTTGGAAGCTGGACTTATCCAAGGTGCTGATCTCGTGGGTAT
GCCAATTTCAGAATATGTGTACGGCAACGTTGCTAAGGCCACTATTCCAACTCTTGTGATCACTGCTTTTGTCCACATGG
CTTGGCAACATCATTGCGACAAAGTAGACGCACGCAAATCAGCACTTCCCACAAGTGATGCTCCTTCGATTCAGCATGAC
ACGTCAGCAGTTGACGACGCGCTCCGGCGCGCCGCTGGCCTCCCCGCATACTATGCCCTACTCCCCTTGCTTCCACTCCT
TCTCATTTTGGTGACAGCCGTCTTACATCGCGCAGACCTACTATCTTTTGAAGCTGGCATTTTGCCGGTGACAATTGTGT
CACTATTCATTTCGCTGATAATCGAAGCCATCCGGCATCGAAGCCTCATGAATGCACTAGAAACAGTGAAACTCTTTTTT
AAAGGCATGGGAGAAGGCGCTGCGGGTGTGGTCGCACTATTGGTTGCAGCTGCGGTACTCGTCGAGGGCGTAACCCAGCT
AGGCGTGATCGATATGCTGATTAATGCTACTGAAGGATCCTCTGGCGCTACTGTGATTATCATTTTGGCATTCGTAGCTT
CAACAGCACTTATGTCAGCTTTAACGGGATCTGGCACTGCCCCTTACTTCGCATTCTCTGAAGTCGTACCGTCACTTGCA
GCCCAGACTGGTGTTCTCCCCGTTCAAATGCTTACGGCAATTTGGGGAACGTCGAATTTGATGCGCCAGGTGTCCCCCGT
CAACGCGGCAGTCATTATTGTTTCGACTGCGATTAATGTCAGCCCTATCAAACTCGTCAAACGTACATCTGTACCGATGA
TTGTTGCCACGATTTTGAACGTTGTGTTTGCATTCCTTTTCATTCACGTTTAG

Upstream 100 bases:

>100_bases
AGATCACCGCGTCAGTTTGGCAAGGTCGAATGCTTTCACACGCAAAGACCAGTGCTCCTTATACGACGCGGACGGTCGCT
ATGTCGAAGGACCTCAGATA

Downstream 100 bases:

>100_bases
TACGCCATACGACATAGAAAAAGGTGGGGGTCCTAGCAAAATACGCTAGGACCCCCACCTTAAAGGTTTTTAATCAGTAC
TGATTAGTTACCAGCAAGCT

Product: putative transport protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 470; Mature: 470

Protein sequence:

>470_residues
MLYLLIALISFAAVMYLIIKKVNAAAAIFFVGVLLLMIAAISGKAEPSVEIKPSGNSFYDELLVIEALFKSRFSGIGMAI
MVLFGFVSYMRTIGADAKAVVLLSAPLQKMRGSYWMVPIGFTIGTALSLIVPSASALSLLLVATLLPALVAAGLTPLTVA
AIIVTSSTIVATPLEAGLIQGADLVGMPISEYVYGNVAKATIPTLVITAFVHMAWQHHCDKVDARKSALPTSDAPSIQHD
TSAVDDALRRAAGLPAYYALLPLLPLLLILVTAVLHRADLLSFEAGILPVTIVSLFISLIIEAIRHRSLMNALETVKLFF
KGMGEGAAGVVALLVAAAVLVEGVTQLGVIDMLINATEGSSGATVIIILAFVASTALMSALTGSGTAPYFAFSEVVPSLA
AQTGVLPVQMLTAIWGTSNLMRQVSPVNAAVIIVSTAINVSPIKLVKRTSVPMIVATILNVVFAFLFIHV

Sequences:

>Translated_470_residues
MLYLLIALISFAAVMYLIIKKVNAAAAIFFVGVLLLMIAAISGKAEPSVEIKPSGNSFYDELLVIEALFKSRFSGIGMAI
MVLFGFVSYMRTIGADAKAVVLLSAPLQKMRGSYWMVPIGFTIGTALSLIVPSASALSLLLVATLLPALVAAGLTPLTVA
AIIVTSSTIVATPLEAGLIQGADLVGMPISEYVYGNVAKATIPTLVITAFVHMAWQHHCDKVDARKSALPTSDAPSIQHD
TSAVDDALRRAAGLPAYYALLPLLPLLLILVTAVLHRADLLSFEAGILPVTIVSLFISLIIEAIRHRSLMNALETVKLFF
KGMGEGAAGVVALLVAAAVLVEGVTQLGVIDMLINATEGSSGATVIIILAFVASTALMSALTGSGTAPYFAFSEVVPSLA
AQTGVLPVQMLTAIWGTSNLMRQVSPVNAAVIIVSTAINVSPIKLVKRTSVPMIVATILNVVFAFLFIHV
>Mature_470_residues
MLYLLIALISFAAVMYLIIKKVNAAAAIFFVGVLLLMIAAISGKAEPSVEIKPSGNSFYDELLVIEALFKSRFSGIGMAI
MVLFGFVSYMRTIGADAKAVVLLSAPLQKMRGSYWMVPIGFTIGTALSLIVPSASALSLLLVATLLPALVAAGLTPLTVA
AIIVTSSTIVATPLEAGLIQGADLVGMPISEYVYGNVAKATIPTLVITAFVHMAWQHHCDKVDARKSALPTSDAPSIQHD
TSAVDDALRRAAGLPAYYALLPLLPLLLILVTAVLHRADLLSFEAGILPVTIVSLFISLIIEAIRHRSLMNALETVKLFF
KGMGEGAAGVVALLVAAAVLVEGVTQLGVIDMLINATEGSSGATVIIILAFVASTALMSALTGSGTAPYFAFSEVVPSLA
AQTGVLPVQMLTAIWGTSNLMRQVSPVNAAVIIVSTAINVSPIKLVKRTSVPMIVATILNVVFAFLFIHV

Specific function: May have a role in the transport of dicarboxylates from the periplasm across the inner membrane. Seems not to be essential for growth. It is likely to be a cryptic gene, as no or low expression has been found under a number of growth conditions and when t

COG id: COG3069

COG function: function code C; C4-dicarboxylate transporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dcuC/dcuD transporter (TC 2.A.61) family [H]

Homologues:

Organism=Escherichia coli, GI1789622, Length=470, Percent_Identity=32.1276595744681, Blast_Score=213, Evalue=2e-56,
Organism=Escherichia coli, GI1786839, Length=436, Percent_Identity=32.3394495412844, Blast_Score=167, Evalue=2e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018385
- InterPro:   IPR004669 [H]

Pfam domain/function: PF03606 DcuC [H]

EC number: NA

Molecular weight: Translated: 49209; Mature: 49209

Theoretical pI: Translated: 8.40; Mature: 8.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLYLLIALISFAAVMYLIIKKVNAAAAIFFVGVLLLMIAAISGKAEPSVEIKPSGNSFYD
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCHHHH
ELLVIEALFKSRFSGIGMAIMVLFGFVSYMRTIGADAKAVVLLSAPLQKMRGSYWMVPIG
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHCCCEEEEEEC
FTIGTALSLIVPSASALSLLLVATLLPALVAAGLTPLTVAAIIVTSSTIVATPLEAGLIQ
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCHHEECCHHHHHHC
GADLVGMPISEYVYGNVAKATIPTLVITAFVHMAWQHHCDKVDARKSALPTSDAPSIQHD
CCCCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCH
TSAVDDALRRAAGLPAYYALLPLLPLLLILVTAVLHRADLLSFEAGILPVTIVSLFISLI
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
IEAIRHRSLMNALETVKLFFKGMGEGAAGVVALLVAAAVLVEGVTQLGVIDMLINATEGS
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
SGATVIIILAFVASTALMSALTGSGTAPYFAFSEVVPSLAAQTGVLPVQMLTAIWGTSNL
CCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHCCHHH
MRQVSPVNAAVIIVSTAINVSPIKLVKRTSVPMIVATILNVVFAFLFIHV
HHHHCCCCEEEEEEEECCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLYLLIALISFAAVMYLIIKKVNAAAAIFFVGVLLLMIAAISGKAEPSVEIKPSGNSFYD
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCHHHH
ELLVIEALFKSRFSGIGMAIMVLFGFVSYMRTIGADAKAVVLLSAPLQKMRGSYWMVPIG
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHCCCEEEEEEC
FTIGTALSLIVPSASALSLLLVATLLPALVAAGLTPLTVAAIIVTSSTIVATPLEAGLIQ
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCHHEECCHHHHHHC
GADLVGMPISEYVYGNVAKATIPTLVITAFVHMAWQHHCDKVDARKSALPTSDAPSIQHD
CCCCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCH
TSAVDDALRRAAGLPAYYALLPLLPLLLILVTAVLHRADLLSFEAGILPVTIVSLFISLI
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
IEAIRHRSLMNALETVKLFFKGMGEGAAGVVALLVAAAVLVEGVTQLGVIDMLINATEGS
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
SGATVIIILAFVASTALMSALTGSGTAPYFAFSEVVPSLAAQTGVLPVQMLTAIWGTSNL
CCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHCCHHH
MRQVSPVNAAVIIVSTAINVSPIKLVKRTSVPMIVATILNVVFAFLFIHV
HHHHCCCCEEEEEEEECCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]