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The map label for this gene is 38233670

Identifier: 38233670

GI number: 38233670

Start: 1057910

End: 1058614

Strand: Reverse

Name: 38233670

Synonym: DIP1076

Alternate gene names: NA

Gene position: 1058614-1057910 (Counterclockwise)

Preceding gene: 38233672

Following gene: 38233667

Centisome position: 42.54

GC content: 47.94

Gene sequence:

>705_bases
ATGAATAACATTGCAGCTCCCGACCAATCTTTTAATCCCGCACATGTCTTGAGTTTCGATTTAGAAACCACCTCTGCCAA
TCCTTTCGAAGCACGCATTGTCACTTCTGCGTTGGTACGAATTGATAGTTCTGGCGCCCATCCTGTGGAATTGCTAGCTG
ATCCAGGAGTAGAAATCCCAGAAGCCGCCAGCAAAGTTCATGGAATTAGCACAGAGTATGCCCGTGAACACGGCGAACCA
CACGAGGCCGTGCTCAAACGCACCGTTGATGAAATCTATGCTGCATGGGAAGAAGGATTCACCCTTGTGGTGTACAACGC
ACCGTACGATTTGACGGTATTACGCCAGCTCACCGGAGATTTTGTTGTTAAGGGCCCAGTGTACGACCCATATTTGATTG
ACCGCATTATGGATCGCTTCCGTAAAGGAAAGCGTACTCTGACCGATTTGTGTTCTGTTTATGGTGTGCGGATGGACAAT
GCTCATGAGGCAACCTCTGATGCCTTAGCCGCTGCACGTATTGCATGGATGCAGGCGAAGAAACGCTTTAAAGACGATCT
AGCGGCCTACTCACATGATGAATTAATGGAGTATCAAGCAGTTCAGTACTACGAGCTGCAAAAAGACATGAAGAAATACC
TCGATGGGCTTGGCCGAGATACATCAACTGTCAATTTCGGGTGGCCAATGCAAAATTCGCGCTAA

Upstream 100 bases:

>100_bases
TCACGCAGCCCAGTGTAGCGGGGTAGGCAATTGCCGTGTTAACAACGCTTTTCGACGCCCAGTTACCCCCATGTCACGGT
TATTCTCTAGGGTAAGCGTT

Downstream 100 bases:

>100_bases
CACACGACCATATGGAGCCACCTCGTGTGAAGCGCTGACAGATTTAAAGGTCACCTGCATCTTCACGCAGCATCGTGCGT
ACCCGCACGATGTGCTGGAG

Product: DNA polymerase III subunit epsilon

Products: diphosphate; DNAn+1

Alternate protein names: DNA Polymerase III Epsilon Subunit; Exonuclease RNAse T And DNA Polymerase III; Exonuclease; DNA Polymerase III; DNA Polymerase III Epsilon Subunit-Like 3-5' Exonuclease; DNA Exonuclease; DNA Polymerase III Subunit Epsilon-Like 3-5' Exonuclease

Number of amino acids: Translated: 234; Mature: 234

Protein sequence:

>234_residues
MNNIAAPDQSFNPAHVLSFDLETTSANPFEARIVTSALVRIDSSGAHPVELLADPGVEIPEAASKVHGISTEYAREHGEP
HEAVLKRTVDEIYAAWEEGFTLVVYNAPYDLTVLRQLTGDFVVKGPVYDPYLIDRIMDRFRKGKRTLTDLCSVYGVRMDN
AHEATSDALAAARIAWMQAKKRFKDDLAAYSHDELMEYQAVQYYELQKDMKKYLDGLGRDTSTVNFGWPMQNSR

Sequences:

>Translated_234_residues
MNNIAAPDQSFNPAHVLSFDLETTSANPFEARIVTSALVRIDSSGAHPVELLADPGVEIPEAASKVHGISTEYAREHGEP
HEAVLKRTVDEIYAAWEEGFTLVVYNAPYDLTVLRQLTGDFVVKGPVYDPYLIDRIMDRFRKGKRTLTDLCSVYGVRMDN
AHEATSDALAAARIAWMQAKKRFKDDLAAYSHDELMEYQAVQYYELQKDMKKYLDGLGRDTSTVNFGWPMQNSR
>Mature_234_residues
MNNIAAPDQSFNPAHVLSFDLETTSANPFEARIVTSALVRIDSSGAHPVELLADPGVEIPEAASKVHGISTEYAREHGEP
HEAVLKRTVDEIYAAWEEGFTLVVYNAPYDLTVLRQLTGDFVVKGPVYDPYLIDRIMDRFRKGKRTLTDLCSVYGVRMDN
AHEATSDALAAARIAWMQAKKRFKDDLAAYSHDELMEYQAVQYYELQKDMKKYLDGLGRDTSTVNFGWPMQNSR

Specific function: Unknown

COG id: COG0847

COG function: function code L; DNA polymerase III, epsilon subunit and related 3'-5' exonucleases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 2.7.7.7

Molecular weight: Translated: 26353; Mature: 26353

Theoretical pI: Translated: 5.00; Mature: 5.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNIAAPDQSFNPAHVLSFDLETTSANPFEARIVTSALVRIDSSGAHPVELLADPGVEIP
CCCCCCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHCCCCCCCCCEECCCCCCCC
EAASKVHGISTEYAREHGEPHEAVLKRTVDEIYAAWEEGFTLVVYNAPYDLTVLRQLTGD
HHHHHHCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHCC
FVVKGPVYDPYLIDRIMDRFRKGKRTLTDLCSVYGVRMDNAHEATSDALAAARIAWMQAK
EEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHH
KRFKDDLAAYSHDELMEYQAVQYYELQKDMKKYLDGLGRDTSTVNFGWPMQNSR
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCC
>Mature Secondary Structure
MNNIAAPDQSFNPAHVLSFDLETTSANPFEARIVTSALVRIDSSGAHPVELLADPGVEIP
CCCCCCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHCCCCCCCCCEECCCCCCCC
EAASKVHGISTEYAREHGEPHEAVLKRTVDEIYAAWEEGFTLVVYNAPYDLTVLRQLTGD
HHHHHHCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHCC
FVVKGPVYDPYLIDRIMDRFRKGKRTLTDLCSVYGVRMDNAHEATSDALAAARIAWMQAK
EEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHH
KRFKDDLAAYSHDELMEYQAVQYYELQKDMKKYLDGLGRDTSTVNFGWPMQNSR
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: deoxynucleoside triphosphate; DNAn

Specific reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1)

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA