Click here to switch to the map view.

The map label for this gene is nudG [H]

Identifier: 38233612

GI number: 38233612

Start: 992898

End: 993293

Strand: Reverse

Name: nudG [H]

Synonym: DIP1017

Alternate gene names: 38233612

Gene position: 993293-992898 (Counterclockwise)

Preceding gene: 38233615

Following gene: 38233611

Centisome position: 39.91

GC content: 47.73

Gene sequence:

>396_bases
ATGAAAAAGCGCATCAAAGTTACCGGCGCAGTTCTCACACGCAACGGCCTCATTCTCGCAGCTCAACGCGGACAATCTAA
GAACCAGGGAAAGTTATGGGAATTCCCTGGAGGAAAAATTGAGCCAGGCGAAACCCCAGAAGAAGCACTCCAGCGCGAAC
TGCACGAAGAATTACGTTGCGACGCTCACGTAGGCAAATTCATTACAACAACGGAATTTGAATATGACTTTGGAATCGTC
GAGTTATCAACTTATTTCTGCACCCTGAATGGATCCGAGCCACAGCTGACTGAACACGAACAAATCAAGTGGCTACGTGC
CAGTGAACTCGCTCAGCTGGACTGGGCACCTGCAGATATACCTACGGTCAAACTTTTAGAAAACTTCACCAACTAA

Upstream 100 bases:

>100_bases
AAATACAGCGAAGTTGATATAAAGTGCGTTCTGTCCGCAGAGTATCCCTGCTCTTCGCAGCATTCAACACAATTCTTTTC
AAACGTTATATCGGAGTGAT

Downstream 100 bases:

>100_bases
GCGACTAAATATGTCTACTGCCGATTCAGCTCTTCCCTTTGGTGTCTATGAAACACCCATTACTCGTAGAATTTCTGAAC
GTCTTACAGAAACTCAAAAG

Product: NUDIX family hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 131; Mature: 131

Protein sequence:

>131_residues
MKKRIKVTGAVLTRNGLILAAQRGQSKNQGKLWEFPGGKIEPGETPEEALQRELHEELRCDAHVGKFITTTEFEYDFGIV
ELSTYFCTLNGSEPQLTEHEQIKWLRASELAQLDWAPADIPTVKLLENFTN

Sequences:

>Translated_131_residues
MKKRIKVTGAVLTRNGLILAAQRGQSKNQGKLWEFPGGKIEPGETPEEALQRELHEELRCDAHVGKFITTTEFEYDFGIV
ELSTYFCTLNGSEPQLTEHEQIKWLRASELAQLDWAPADIPTVKLLENFTN
>Mature_131_residues
MKKRIKVTGAVLTRNGLILAAQRGQSKNQGKLWEFPGGKIEPGETPEEALQRELHEELRCDAHVGKFITTTEFEYDFGIV
ELSTYFCTLNGSEPQLTEHEQIKWLRASELAQLDWAPADIPTVKLLENFTN

Specific function: Specific for pyrimidine substrates. Acts on 5-methyl- dCTP, CTP and dCTP in decreasing order [H]

COG id: COG0494

COG function: function code LR; NTP pyrophosphohydrolases including oxidative damage repair enzymes

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 nudix hydrolase domain [H]

Homologues:

Organism=Escherichia coli, GI1788056, Length=128, Percent_Identity=40.625, Blast_Score=92, Evalue=2e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020476
- InterPro:   IPR020084
- InterPro:   IPR000086
- InterPro:   IPR015797 [H]

Pfam domain/function: PF00293 NUDIX [H]

EC number: 3.6.1.-

Molecular weight: Translated: 14858; Mature: 14858

Theoretical pI: Translated: 5.01; Mature: 5.01

Prosite motif: PS00893 NUDIX

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKRIKVTGAVLTRNGLILAAQRGQSKNQGKLWEFPGGKIEPGETPEEALQRELHEELRC
CCCEEEEEEEEEECCCEEEEECCCCCCCCCCEEECCCCCCCCCCCHHHHHHHHHHHHHCC
DAHVGKFITTTEFEYDFGIVELSTYFCTLNGSEPQLTEHEQIKWLRASELAQLDWAPADI
CCCCCCEEEEEECCCCCCEEEEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCCCC
PTVKLLENFTN
CHHHHHHHCCC
>Mature Secondary Structure
MKKRIKVTGAVLTRNGLILAAQRGQSKNQGKLWEFPGGKIEPGETPEEALQRELHEELRC
CCCEEEEEEEEEECCCEEEEECCCCCCCCCCEEECCCCCCCCCCCHHHHHHHHHHHHHCC
DAHVGKFITTTEFEYDFGIVELSTYFCTLNGSEPQLTEHEQIKWLRASELAQLDWAPADI
CCCCCCEEEEEECCCCCCEEEEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCCCC
PTVKLLENFTN
CHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Fe; Mn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503; 11053429 [H]