Click here to switch to the map view.

The map label for this gene is lacA

Identifier: 15925185

GI number: 15925185

Start: 2338098

End: 2338526

Strand: Reverse

Name: lacA

Synonym: SAV2195

Alternate gene names: 15925185

Gene position: 2338526-2338098 (Counterclockwise)

Preceding gene: 15925186

Following gene: 15925184

Centisome position: 81.24

GC content: 36.6

Gene sequence:

>429_bases
ATGGCGATTATTATTGGTTCAGATGAAGCTGGCAAACGATTAAAAGAAGTCATCAAATCATACTTATTAGACAATAAATA
TGATGTTGTTGACGTAACAGAAGGACAGGAAGTTGACTTTGTTGATGCAACTTTGGCTGTAGCAAAAGATGTTCAAAGTC
AAGAAGGTAACTTAGGTATTGTTATCGATGCATTTGGTGCAGGTAGCTTTATGGTTGCTACAAAAATCAAAGGCATGATT
GCTGCTGAAGTATCAGATGAACGCTCTGGATATATGACTAGAGGCCATAACAATTCAAGAATGATCACTATGGGATCTGA
AATTGTTGGAGACACATTAGCGAAAAATGTCGTTAAAGGTTTTGTTGAAGGTAAATACGATGGTGGTAGACACCAAATCC
GCGTAGATATGCTTAATAAAATGTGCTAA

Upstream 100 bases:

>100_bases
TCAAATTGAAAGCCTTTTCTCAAGATTTTCATAAGCTACAAATAAATATGTCATATTTTAAGAAAGGTATTTCAAAATTA
AAGTAAAAAGGAGTCTTATT

Downstream 100 bases:

>100_bases
GGAGGAAAAATTACTATGAAGATTGCATTAGGATGCGACCATATTGTTACAGATACAAAAATGCGTGTATCTGAATTTTT
AAAATCAAAAGGACATGAAG

Product: galactose-6-phosphate isomerase subunit LacA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 142; Mature: 141

Protein sequence:

>142_residues
MAIIIGSDEAGKRLKEVIKSYLLDNKYDVVDVTEGQEVDFVDATLAVAKDVQSQEGNLGIVIDAFGAGSFMVATKIKGMI
AAEVSDERSGYMTRGHNNSRMITMGSEIVGDTLAKNVVKGFVEGKYDGGRHQIRVDMLNKMC

Sequences:

>Translated_142_residues
MAIIIGSDEAGKRLKEVIKSYLLDNKYDVVDVTEGQEVDFVDATLAVAKDVQSQEGNLGIVIDAFGAGSFMVATKIKGMI
AAEVSDERSGYMTRGHNNSRMITMGSEIVGDTLAKNVVKGFVEGKYDGGRHQIRVDMLNKMC
>Mature_141_residues
AIIIGSDEAGKRLKEVIKSYLLDNKYDVVDVTEGQEVDFVDATLAVAKDVQSQEGNLGIVIDAFGAGSFMVATKIKGMIA
AEVSDERSGYMTRGHNNSRMITMGSEIVGDTLAKNVVKGFVEGKYDGGRHQIRVDMLNKMC

Specific function: In Addition To Its Activity On D-Ribose 5-Phosphate It Probably Also Has Activity On D-Allose 6-Phosphate. [C]

COG id: COG0698

COG function: function code G; Ribose 5-phosphate isomerase RpiB

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lacAB/rpiB family

Homologues:

Organism=Escherichia coli, GI1790528, Length=141, Percent_Identity=31.9148936170213, Blast_Score=74, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): LACA_STAA1 (A7X579)

Other databases:

- EMBL:   AP009324
- RefSeq:   YP_001442769.1
- ProteinModelPortal:   A7X579
- SMR:   A7X579
- STRING:   A7X579
- EnsemblBacteria:   EBSTAT00000003021
- GeneID:   5561476
- GenomeReviews:   AP009324_GR
- KEGG:   saw:SAHV_2179
- eggNOG:   COG0698
- GeneTree:   EBGT00050000024804
- HOGENOM:   HBG636953
- OMA:   SAMASNK
- ProtClustDB:   PRK08621
- BioCyc:   SAUR418127:SAHV_2179-MONOMER
- HAMAP:   MF_01555
- InterPro:   IPR004783
- InterPro:   IPR003500
- Gene3D:   G3DSA:3.40.1400.10
- PIRSF:   PIRSF005384
- TIGRFAMs:   TIGR01118
- TIGRFAMs:   TIGR00689

Pfam domain/function: PF02502 LacAB_rpiB; SSF89623 Rib/Gal_isomrase

EC number: =5.3.1.26

Molecular weight: Translated: 15395; Mature: 15264

Theoretical pI: Translated: 4.97; Mature: 4.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
5.6 %Met     (Translated Protein)
6.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
5.0 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIIIGSDEAGKRLKEVIKSYLLDNKYDVVDVTEGQEVDFVDATLAVAKDVQSQEGNLGI
CEEEECCCHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCHHHHHHHHHHHHHCCCCCEEE
VIDAFGAGSFMVATKIKGMIAAEVSDERSGYMTRGHNNSRMITMGSEIVGDTLAKNVVKG
EEEECCCCCEEEEEHHCCEEEEECCCCCCCCEECCCCCCEEEEECHHHHHHHHHHHHHHH
FVEGKYDGGRHQIRVDMLNKMC
HHCCCCCCCCEEEEEEHHHCCC
>Mature Secondary Structure 
AIIIGSDEAGKRLKEVIKSYLLDNKYDVVDVTEGQEVDFVDATLAVAKDVQSQEGNLGI
EEEECCCHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCHHHHHHHHHHHHHCCCCCEEE
VIDAFGAGSFMVATKIKGMIAAEVSDERSGYMTRGHNNSRMITMGSEIVGDTLAKNVVKG
EEEECCCCCEEEEEHHCCEEEEECCCCCCCCEECCCCCCEEEEECHHHHHHHHHHHHHHH
FVEGKYDGGRHQIRVDMLNKMC
HHCCCCCCCCEEEEEEHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA