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The map label for this gene is htsA [H]

Identifier: 15925167

GI number: 15925167

Start: 2317468

End: 2318451

Strand: Reverse

Name: htsA [H]

Synonym: SAV2177

Alternate gene names: 15925167

Gene position: 2318451-2317468 (Counterclockwise)

Preceding gene: 15925168

Following gene: 15925166

Centisome position: 80.54

GC content: 30.89

Gene sequence:

>984_bases
ATGAGAGGTCTAAAAACTTTTAGTATATTGGGATTAATAGTTGCCTTACTTTTAGTTGCAGCTTGTGGTAATACGGATAA
TTCAAGTAAAAAAGAATCATCAACTAAAGATACTATTTCGGTAAAAGATGAAAATGGTACAGTAAAAGTACCTAAAGATG
CAAAACGTATCGTTGTATTAGAGTACTCATTTGCAGATGCATTAGCAGCATTAGACGTTAAACCAGTTGGTATTGCTGAT
GATGGTAAGAAAAAACGTATCATTAAACCAGTTAGAGAAAAAATTGGGGATTATACTTCTGTAGGTACACGTAAACAGCC
AAACTTAGAGGAAATTAGTAAATTAAAACCGGATTTAATTATCGCTGATAGCAGTAGACATAAAGGTATTAATAAAGAAT
TAAACAAAATTGCACCAACATTATCATTAAAGAGTTTTGATGGAGACTACAAACAAAATATTAATTCGTTCAAAACAATT
GCTAAAGCTTTAAATAAAGAAAAAGAAGGCGAAAAACGTCTTGCTGAGCATGATAAATTAATCAATAAGTATAAAGATGA
AATTAAATTTGATAGAAATCAAAAAGTGCTTCCAGCAGTAGTTGCTAAAGCTGGTTTATTAGCACATCCAAACTATTCAT
ATGTTGGACAATTTTTAAACGAACTAGGATTTAAAAATGCATTAAGTGACGATGTAACAAAAGGTTTAAGTAAATATTTG
AAAGGACCTTACTTACAATTAGACACTGAACATTTAGCTGATTTAAATCCAGAGCGTATGATCATTATGACAGATCATGC
TAAAAAAGATTCTGCTGAATTCAAGAAGTTACAAGAAGATGCAACATGGAAAAAGTTGAATGCAGTTAAAAATAATCGCG
TGGATATTGTTGACCGTGATGTTTGGGCAAGATCTCGTGGCTTAATTTCTTCTGAAGAAATGGCTAAAGAACTTGTTGAA
TTATCAAAAAAAGAACAAAAGTAA

Upstream 100 bases:

>100_bases
ATACATTTTAGAAATATAAAAAAGATTGAACGCTACTTGACAATGATAATTGTTATCAATAAAATAATAAATGAAGTTAT
ACATATTAAGGAGTGGAACG

Downstream 100 bases:

>100_bases
GGTGGAAGTAAATGGCTATAAAAGAAATAAGTAGCCAATCTGCCATAGATCATAAAAGAAAAAGACGCACAACACTCACG
TATATAGTGAGTTTGTGCTT

Product: heme transport system lipoprotein

Products: ADP; phosphate; iron dicitrate [Cytoplasm] [C]

Alternate protein names: Ferric-citrate-binding protein [H]

Number of amino acids: Translated: 327; Mature: 327

Protein sequence:

>327_residues
MRGLKTFSILGLIVALLLVAACGNTDNSSKKESSTKDTISVKDENGTVKVPKDAKRIVVLEYSFADALAALDVKPVGIAD
DGKKKRIIKPVREKIGDYTSVGTRKQPNLEEISKLKPDLIIADSSRHKGINKELNKIAPTLSLKSFDGDYKQNINSFKTI
AKALNKEKEGEKRLAEHDKLINKYKDEIKFDRNQKVLPAVVAKAGLLAHPNYSYVGQFLNELGFKNALSDDVTKGLSKYL
KGPYLQLDTEHLADLNPERMIIMTDHAKKDSAEFKKLQEDATWKKLNAVKNNRVDIVDRDVWARSRGLISSEEMAKELVE
LSKKEQK

Sequences:

>Translated_327_residues
MRGLKTFSILGLIVALLLVAACGNTDNSSKKESSTKDTISVKDENGTVKVPKDAKRIVVLEYSFADALAALDVKPVGIAD
DGKKKRIIKPVREKIGDYTSVGTRKQPNLEEISKLKPDLIIADSSRHKGINKELNKIAPTLSLKSFDGDYKQNINSFKTI
AKALNKEKEGEKRLAEHDKLINKYKDEIKFDRNQKVLPAVVAKAGLLAHPNYSYVGQFLNELGFKNALSDDVTKGLSKYL
KGPYLQLDTEHLADLNPERMIIMTDHAKKDSAEFKKLQEDATWKKLNAVKNNRVDIVDRDVWARSRGLISSEEMAKELVE
LSKKEQK
>Mature_327_residues
MRGLKTFSILGLIVALLLVAACGNTDNSSKKESSTKDTISVKDENGTVKVPKDAKRIVVLEYSFADALAALDVKPVGIAD
DGKKKRIIKPVREKIGDYTSVGTRKQPNLEEISKLKPDLIIADSSRHKGINKELNKIAPTLSLKSFDGDYKQNINSFKTI
AKALNKEKEGEKRLAEHDKLINKYKDEIKFDRNQKVLPAVVAKAGLLAHPNYSYVGQFLNELGFKNALSDDVTKGLSKYL
KGPYLQLDTEHLADLNPERMIIMTDHAKKDSAEFKKLQEDATWKKLNAVKNNRVDIVDRDVWARSRGLISSEEMAKELVE
LSKKEQK

Specific function: Part of the ABC transporter complex yfmCDEF involved in citrate-dependent Fe(3+) import. Binds citrate-dependent Fe(3+) and delivers it to the surface of yfmDE (Probable) [H]

COG id: COG4594

COG function: function code P; ABC-type Fe3+-citrate transport system, periplasmic component

Gene ontology:

Cell location: Cell membrane; Lipid-anchor (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 Fe/B12 periplasmic-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87082411, Length=283, Percent_Identity=36.7491166077738, Blast_Score=187, Evalue=1e-48,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002491 [H]

Pfam domain/function: PF01497 Peripla_BP_2 [H]

EC number: NA

Molecular weight: Translated: 36592; Mature: 36592

Theoretical pI: Translated: 10.05; Mature: 10.05

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS50983 FE_B12_PBP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRGLKTFSILGLIVALLLVAACGNTDNSSKKESSTKDTISVKDENGTVKVPKDAKRIVVL
CCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEECCCCCEECCCCCCEEEEE
EYSFADALAALDVKPVGIADDGKKKRIIKPVREKIGDYTSVGTRKQPNLEEISKLKPDLI
EECHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCHHCCCCCCCCCHHHHHHCCCCEE
IADSSRHKGINKELNKIAPTLSLKSFDGDYKQNINSFKTIAKALNKEKEGEKRLAEHDKL
EECCCCCCCCHHHHHHHHCCCEECCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
INKYKDEIKFDRNQKVLPAVVAKAGLLAHPNYSYVGQFLNELGFKNALSDDVTKGLSKYL
HHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
KGPYLQLDTEHLADLNPERMIIMTDHAKKDSAEFKKLQEDATWKKLNAVKNNRVDIVDRD
CCCCEEECHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEECHH
VWARSRGLISSEEMAKELVELSKKEQK
HHHHHCCCCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MRGLKTFSILGLIVALLLVAACGNTDNSSKKESSTKDTISVKDENGTVKVPKDAKRIVVL
CCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEECCCCCEECCCCCCEEEEE
EYSFADALAALDVKPVGIADDGKKKRIIKPVREKIGDYTSVGTRKQPNLEEISKLKPDLI
EECHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCHHCCCCCCCCCHHHHHHCCCCEE
IADSSRHKGINKELNKIAPTLSLKSFDGDYKQNINSFKTIAKALNKEKEGEKRLAEHDKL
EECCCCCCCCHHHHHHHHCCCEECCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
INKYKDEIKFDRNQKVLPAVVAKAGLLAHPNYSYVGQFLNELGFKNALSDDVTKGLSKYL
HHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
KGPYLQLDTEHLADLNPERMIIMTDHAKKDSAEFKKLQEDATWKKLNAVKNNRVDIVDRD
CCCCEEECHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEECHH
VWARSRGLISSEEMAKELVELSKKEQK
HHHHHCCCCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; iron dicitrate [Periplasm]; H2O [C]

Specific reaction: ATP + iron dicitrate [Periplasm] + H2O = ADP + phosphate + iron dicitrate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9272861; 9384377 [H]