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The map label for this gene is htsB [H]

Identifier: 15925166

GI number: 15925166

Start: 2316425

End: 2317456

Strand: Reverse

Name: htsB [H]

Synonym: SAV2176

Alternate gene names: 15925166

Gene position: 2317456-2316425 (Counterclockwise)

Preceding gene: 15925167

Following gene: 15925165

Centisome position: 80.51

GC content: 34.3

Gene sequence:

>1032_bases
ATGGCTATAAAAGAAATAAGTAGCCAATCTGCCATAGATCATAAAAGAAAAAGACGCACAACACTCACGTATATAGTGAG
TTTGTGCTTTCTTTTTATTTGTATATATTTAAATATGGCGATTGGTTCTTCGAAAATTAATTTTAGCGATATCATTCACT
ATGTTACTGGTCATACAGATACGAAAGCAACGTTTTTATTGCATAATGTACGTATGCCAAGGATGATTGCAGGGTTATTT
ATTGGCGGTGCATTAGCGGTATCTGGTTTGTTAATGCAAGCAATGACACGCAATCCGCTAGCATCACCTAAAATTTTTGG
TGTCAGTTCTGGTGCATCGTTTTTCATTGTATTTGTGACGATTATCATTCCATCATTAGAATATTATGCATTATATTTAG
GTGTGATAGGTGCATTTATAGGTGGTTTAACTGTTTATACACTTTCAGGTGCTACGAAAGGTATGACACCCATTAAATTA
GCATTGGCTGGTATGGCCATCCATTTGTTTTTTAGTAGTATGACTGAAGGTATTATTATTTTGAATGAGAATTCAAACGA
ACAAGTGATGTTTTGGCTTGTCGGTTCATTATCCAGTATGAAGTGGGATGAAATTTTAACCATTTTACCATGGATTATTG
GTGCTTTAATTGTAACGATTTTTATTGGACGTCAACTAACGATTATGGAACTAGGCGATGACATTGCTAAGGGATTGGGT
CAAAATATAAATAAAGTTAGAATTATCATTGGGCTATTAGTCATTATTCTTACAGGTATGTCGGTGTCAGTGGCAGGACC
AATTGGATTTGTTGGCTTAATCGTACCGCATATAGTCAAACGCTATGTGAGTAAGAATTATTTAGTCATGATTCCATTAA
CATTTATTATAGGTGCAGATTTGTTACTACTATCAGATGTATTAAGTCGTTTAATCACTTATCCTTACGAATCACCTGTA
GGTATTGTGACATCATTCGTAGGTGCACTTTACTTCTTATTTATAACGATTAAAGGGGTGAAAAGAATATGA

Upstream 100 bases:

>100_bases
GTGATGTTTGGGCAAGATCTCGTGGCTTAATTTCTTCTGAAGAAATGGCTAAAGAACTTGTTGAATTATCAAAAAAAGAA
CAAAAGTAAGGTGGAAGTAA

Downstream 100 bases:

>100_bases
TGACAACGAAAATTATACGTCGTTATAGTTTAATCACAATCCTTTTAATTGTGAGTATATTCATAAGTTTATGTGTAGGG
TCTGTCATGATTCATCCGAT

Product: heme transport system permease

Products: ADP; phosphate; iron dicitrate [Cytoplasm] [C]

Alternate protein names: Ferric-citrate import system permease protein [H]

Number of amino acids: Translated: 343; Mature: 342

Protein sequence:

>343_residues
MAIKEISSQSAIDHKRKRRTTLTYIVSLCFLFICIYLNMAIGSSKINFSDIIHYVTGHTDTKATFLLHNVRMPRMIAGLF
IGGALAVSGLLMQAMTRNPLASPKIFGVSSGASFFIVFVTIIIPSLEYYALYLGVIGAFIGGLTVYTLSGATKGMTPIKL
ALAGMAIHLFFSSMTEGIIILNENSNEQVMFWLVGSLSSMKWDEILTILPWIIGALIVTIFIGRQLTIMELGDDIAKGLG
QNINKVRIIIGLLVIILTGMSVSVAGPIGFVGLIVPHIVKRYVSKNYLVMIPLTFIIGADLLLLSDVLSRLITYPYESPV
GIVTSFVGALYFLFITIKGVKRI

Sequences:

>Translated_343_residues
MAIKEISSQSAIDHKRKRRTTLTYIVSLCFLFICIYLNMAIGSSKINFSDIIHYVTGHTDTKATFLLHNVRMPRMIAGLF
IGGALAVSGLLMQAMTRNPLASPKIFGVSSGASFFIVFVTIIIPSLEYYALYLGVIGAFIGGLTVYTLSGATKGMTPIKL
ALAGMAIHLFFSSMTEGIIILNENSNEQVMFWLVGSLSSMKWDEILTILPWIIGALIVTIFIGRQLTIMELGDDIAKGLG
QNINKVRIIIGLLVIILTGMSVSVAGPIGFVGLIVPHIVKRYVSKNYLVMIPLTFIIGADLLLLSDVLSRLITYPYESPV
GIVTSFVGALYFLFITIKGVKRI
>Mature_342_residues
AIKEISSQSAIDHKRKRRTTLTYIVSLCFLFICIYLNMAIGSSKINFSDIIHYVTGHTDTKATFLLHNVRMPRMIAGLFI
GGALAVSGLLMQAMTRNPLASPKIFGVSSGASFFIVFVTIIIPSLEYYALYLGVIGAFIGGLTVYTLSGATKGMTPIKLA
LAGMAIHLFFSSMTEGIIILNENSNEQVMFWLVGSLSSMKWDEILTILPWIIGALIVTIFIGRQLTIMELGDDIAKGLGQ
NINKVRIIIGLLVIILTGMSVSVAGPIGFVGLIVPHIVKRYVSKNYLVMIPLTFIIGADLLLLSDVLSRLITYPYESPVG
IVTSFVGALYFLFITIKGVKRI

Specific function: Part of the ABC transporter complex yfmCDEF involved in citrate-dependent Fe(3+) import. Involved in the translocation of the substrate across the membrane (Probable) [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790741, Length=285, Percent_Identity=33.3333333333333, Blast_Score=165, Evalue=4e-42,
Organism=Escherichia coli, GI1790740, Length=307, Percent_Identity=32.8990228013029, Blast_Score=161, Evalue=7e-41,
Organism=Escherichia coli, GI1786805, Length=303, Percent_Identity=32.013201320132, Blast_Score=136, Evalue=2e-33,
Organism=Escherichia coli, GI1786347, Length=275, Percent_Identity=32, Blast_Score=136, Evalue=2e-33,
Organism=Escherichia coli, GI1788004, Length=280, Percent_Identity=33.2142857142857, Blast_Score=118, Evalue=5e-28,
Organism=Escherichia coli, GI1786804, Length=332, Percent_Identity=26.5060240963855, Blast_Score=110, Evalue=9e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000522 [H]

Pfam domain/function: PF01032 FecCD [H]

EC number: NA

Molecular weight: Translated: 37467; Mature: 37336

Theoretical pI: Translated: 9.97; Mature: 9.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIKEISSQSAIDHKRKRRTTLTYIVSLCFLFICIYLNMAIGSSKINFSDIIHYVTGHTD
CCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCC
TKATFLLHNVRMPRMIAGLFIGGALAVSGLLMQAMTRNPLASPKIFGVSSGASFFIVFVT
CHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCHHHHHHHH
IIIPSLEYYALYLGVIGAFIGGLTVYTLSGATKGMTPIKLALAGMAIHLFFSSMTEGIII
HHHCCHHHHHHHHHHHHHHHHHHHEEEECCCCCCCCHHHHHHHHHHHHHHHHHHCCCEEE
LNENSNEQVMFWLVGSLSSMKWDEILTILPWIIGALIVTIFIGRQLTIMELGDDIAKGLG
EECCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEHHHCHHHHHHHC
QNINKVRIIIGLLVIILTGMSVSVAGPIGFVGLIVPHIVKRYVSKNYLVMIPLTFIIGAD
CCHHHHHHHHHHHHHHHCCCCEEECCHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHH
LLLLSDVLSRLITYPYESPVGIVTSFVGALYFLFITIKGVKRI
HHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AIKEISSQSAIDHKRKRRTTLTYIVSLCFLFICIYLNMAIGSSKINFSDIIHYVTGHTD
CCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCC
TKATFLLHNVRMPRMIAGLFIGGALAVSGLLMQAMTRNPLASPKIFGVSSGASFFIVFVT
CHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCHHHHHHHH
IIIPSLEYYALYLGVIGAFIGGLTVYTLSGATKGMTPIKLALAGMAIHLFFSSMTEGIII
HHHCCHHHHHHHHHHHHHHHHHHHEEEECCCCCCCCHHHHHHHHHHHHHHHHHHCCCEEE
LNENSNEQVMFWLVGSLSSMKWDEILTILPWIIGALIVTIFIGRQLTIMELGDDIAKGLG
EECCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEHHHCHHHHHHHC
QNINKVRIIIGLLVIILTGMSVSVAGPIGFVGLIVPHIVKRYVSKNYLVMIPLTFIIGAD
CCHHHHHHHHHHHHHHHCCCCEEECCHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHH
LLLLSDVLSRLITYPYESPVGIVTSFVGALYFLFITIKGVKRI
HHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; iron dicitrate [Periplasm]; H2O [C]

Specific reaction: ATP + iron dicitrate [Periplasm] + H2O = ADP + phosphate + iron dicitrate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9272861; 9384377 [H]