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The map label for this gene is htsC [H]

Identifier: 15925165

GI number: 15925165

Start: 2315460

End: 2316428

Strand: Reverse

Name: htsC [H]

Synonym: SAV2175

Alternate gene names: 15925165

Gene position: 2316428-2315460 (Counterclockwise)

Preceding gene: 15925166

Following gene: 15925164

Centisome position: 80.47

GC content: 33.44

Gene sequence:

>969_bases
ATGATGACAACGAAAATTATACGTCGTTATAGTTTAATCACAATCCTTTTAATTGTGAGTATATTCATAAGTTTATGTGT
AGGGTCTGTCATGATTCATCCGATTGATGCTATTAAGGGAATCTTTACACAAGATGATTTTATTTTAAATGAGTATCGTA
TACCTAGAACATTACTTGGTATTATTATCGGTAGTAGCTTGGCTATATCAGGTGCAATTATACAAGCTGTAATAAGAAAC
CCGTTAGCCTCACCTGATGTTATAGGTATTTCTAAAGGTGCCAGTTTAGCTGCTGTAATTATTATTATGATCTTTCCAAC
AGCACCATTGTTTGTTTTACCTATAGGTTCATTCTTAGGTGCCTTTGCAGTAAGTTTATTTTTATCATTTTTAATTTCAA
AATATGATGTTAAAGGTTCAAAGCTTGCCTTAATTGGTTTAGCAATAGGCGCAATATGTACGGCGATTGTGCAGTTCTTA
TTAATCAGAAATCCACTGGAAGCAAACAAAGCGCTTGTTTGGTTGACAGGTAGTCTATATGGACATGATATGTCGAATAT
TTATACTATATTACCTTGGTTTTTAATAACGATACCAATCATCATTTTATTGAGTTATCAATTAGATGTATTGAATCTAG
GTGATGCTGTTGCAACCGCACTCGGTTTAAAAGTTAAAACTATTAAAATGCTATTGCTAATTTTAGCAGTAATATTAGCA
GGATCCGCAATTTCAGTTGTCGGTGGTATTAGCTTTTTAGGATTAATTGCACCTCATATTGCGAGACAATTAATAGGAAA
TAAAACATTACACGTTATTATCATGTCGGGGTTAATTGGTGCTATATTGTTAACATTTGGAGATGGTTTAGCCCGTGGCA
TTCATCCGCCACTGGATATTCCTGTAGGGGTTATCATTGCAATTATCGGTGCACCATACTTCTTAATATTATTACGAAGA
ATGAAATAA

Upstream 100 bases:

>100_bases
GTTTAATCACTTATCCTTACGAATCACCTGTAGGTATTGTGACATCATTCGTAGGTGCACTTTACTTCTTATTTATAACG
ATTAAAGGGGTGAAAAGAAT

Downstream 100 bases:

>100_bases
CTAACATATGATTAGAGTTTAAAAAAGGTTAAGTACGAAATCAGTAATTGTACTTAACCTTTTTTGAATTCATCTTGAAA
AATTACAAGTAATAGCGTAT

Product: heme transport system permease

Products: ADP; phosphate; iron dicitrate [Cytoplasm] [C]

Alternate protein names: Ferric-citrate import system permease protein [H]

Number of amino acids: Translated: 322; Mature: 322

Protein sequence:

>322_residues
MMTTKIIRRYSLITILLIVSIFISLCVGSVMIHPIDAIKGIFTQDDFILNEYRIPRTLLGIIIGSSLAISGAIIQAVIRN
PLASPDVIGISKGASLAAVIIIMIFPTAPLFVLPIGSFLGAFAVSLFLSFLISKYDVKGSKLALIGLAIGAICTAIVQFL
LIRNPLEANKALVWLTGSLYGHDMSNIYTILPWFLITIPIIILLSYQLDVLNLGDAVATALGLKVKTIKMLLLILAVILA
GSAISVVGGISFLGLIAPHIARQLIGNKTLHVIIMSGLIGAILLTFGDGLARGIHPPLDIPVGVIIAIIGAPYFLILLRR
MK

Sequences:

>Translated_322_residues
MMTTKIIRRYSLITILLIVSIFISLCVGSVMIHPIDAIKGIFTQDDFILNEYRIPRTLLGIIIGSSLAISGAIIQAVIRN
PLASPDVIGISKGASLAAVIIIMIFPTAPLFVLPIGSFLGAFAVSLFLSFLISKYDVKGSKLALIGLAIGAICTAIVQFL
LIRNPLEANKALVWLTGSLYGHDMSNIYTILPWFLITIPIIILLSYQLDVLNLGDAVATALGLKVKTIKMLLLILAVILA
GSAISVVGGISFLGLIAPHIARQLIGNKTLHVIIMSGLIGAILLTFGDGLARGIHPPLDIPVGVIIAIIGAPYFLILLRR
MK
>Mature_322_residues
MMTTKIIRRYSLITILLIVSIFISLCVGSVMIHPIDAIKGIFTQDDFILNEYRIPRTLLGIIIGSSLAISGAIIQAVIRN
PLASPDVIGISKGASLAAVIIIMIFPTAPLFVLPIGSFLGAFAVSLFLSFLISKYDVKGSKLALIGLAIGAICTAIVQFL
LIRNPLEANKALVWLTGSLYGHDMSNIYTILPWFLITIPIIILLSYQLDVLNLGDAVATALGLKVKTIKMLLLILAVILA
GSAISVVGGISFLGLIAPHIARQLIGNKTLHVIIMSGLIGAILLTFGDGLARGIHPPLDIPVGVIIAIIGAPYFLILLRR
MK

Specific function: Part of the ABC transporter complex yfmCDEF involved in citrate-dependent Fe(3+) import. Involved in the translocation of the substrate across the membrane (Probable) [H]

COG id: COG0609

COG function: function code P; ABC-type Fe3+-siderophore transport system, permease component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790740, Length=279, Percent_Identity=41.9354838709677, Blast_Score=218, Evalue=4e-58,
Organism=Escherichia coli, GI1790741, Length=326, Percent_Identity=30.9815950920245, Blast_Score=135, Evalue=3e-33,
Organism=Escherichia coli, GI1786347, Length=309, Percent_Identity=32.3624595469256, Blast_Score=135, Evalue=3e-33,
Organism=Escherichia coli, GI1786804, Length=322, Percent_Identity=31.6770186335404, Blast_Score=123, Evalue=2e-29,
Organism=Escherichia coli, GI1786805, Length=295, Percent_Identity=34.2372881355932, Blast_Score=115, Evalue=4e-27,
Organism=Escherichia coli, GI1788004, Length=301, Percent_Identity=29.9003322259136, Blast_Score=114, Evalue=1e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000522 [H]

Pfam domain/function: PF01032 FecCD [H]

EC number: NA

Molecular weight: Translated: 34361; Mature: 34361

Theoretical pI: Translated: 10.28; Mature: 10.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMTTKIIRRYSLITILLIVSIFISLCVGSVMIHPIDAIKGIFTQDDFILNEYRIPRTLLG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCHHHHHH
IIIGSSLAISGAIIQAVIRNPLASPDVIGISKGASLAAVIIIMIFPTAPLFVLPIGSFLG
HHHHHHHHHHHHHHHHHHHCCCCCCCCEECCCCCHHHHHHHHHHHCCCCHHHHHHHHHHH
AFAVSLFLSFLISKYDVKGSKLALIGLAIGAICTAIVQFLLIRNPLEANKALVWLTGSLY
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCC
GHDMSNIYTILPWFLITIPIIILLSYQLDVLNLGDAVATALGLKVKTIKMLLLILAVILA
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCHHHHHHHHCCHHHHHHHHHHHHHHHHC
GSAISVVGGISFLGLIAPHIARQLIGNKTLHVIIMSGLIGAILLTFGDGLARGIHPPLDI
CCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCC
PVGVIIAIIGAPYFLILLRRMK
CHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MMTTKIIRRYSLITILLIVSIFISLCVGSVMIHPIDAIKGIFTQDDFILNEYRIPRTLLG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCHHHHHH
IIIGSSLAISGAIIQAVIRNPLASPDVIGISKGASLAAVIIIMIFPTAPLFVLPIGSFLG
HHHHHHHHHHHHHHHHHHHCCCCCCCCEECCCCCHHHHHHHHHHHCCCCHHHHHHHHHHH
AFAVSLFLSFLISKYDVKGSKLALIGLAIGAICTAIVQFLLIRNPLEANKALVWLTGSLY
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCC
GHDMSNIYTILPWFLITIPIIILLSYQLDVLNLGDAVATALGLKVKTIKMLLLILAVILA
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCHHHHHHHHCCHHHHHHHHHHHHHHHHC
GSAISVVGGISFLGLIAPHIARQLIGNKTLHVIIMSGLIGAILLTFGDGLARGIHPPLDI
CCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCC
PVGVIIAIIGAPYFLILLRRMK
CHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; iron dicitrate [Periplasm]; H2O [C]

Specific reaction: ATP + iron dicitrate [Periplasm] + H2O = ADP + phosphate + iron dicitrate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9272861; 9384377 [H]