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The map label for this gene is arg

Identifier: 15925154

GI number: 15925154

Start: 2298902

End: 2299810

Strand: Reverse

Name: arg

Synonym: SAV2164

Alternate gene names: 15925154

Gene position: 2299810-2298902 (Counterclockwise)

Preceding gene: 15925155

Following gene: 15925153

Centisome position: 79.9

GC content: 31.57

Gene sequence:

>909_bases
ATGACAAAGACAAAAGCAATTGATATTATAGGTGCACCATCAACATTTGGACAAAGAAAATTAGGTGTTGATTTAGGACC
AACAGCAATTAGATATGCTGGATTAATTTCAAGATTAAAGCAATTAGACCTTGATGTATATGACAAGGGGGATATTAAGG
TACCTGCTGTGAACATTGAAAAATTTCATAGTGAACAAAAAGGATTAAGAAATTATGATGAAATTATAGATGTTAATCAA
AAATTAAATAAAGAGGTTTCAGCATCAATTGAAAATAACAGATTTCCTCTAGTTCTTGGTGGTGATCATTCTATTGCGGT
AGGTTCAGTATCAGCAATAAGTAAACATTATAATAATTTAGGTGTTATTTGGTATGATGCACATGGTGATTTAAATATAC
CTGAAGAGTCACCAAGTGGAAATATTCATGGTATGCCTCTAAGGATTTTGACAGGCGAAGGTCCCAAAGAACTTTTAGAA
TTAAATAGTAATGTAATCAAGCCAGAAAACATCGTACTAATTGGTATGAGAGATTTAGATAAAGGTGAAAGACAATTTAT
CAAAGATCATAATATTAAAACATTTACTATGTCAGATATTGATAAATTAGGGATAAAGGAAGTAATTGAAAATACAATAG
AATATTTGAAGTCACGCAATGTTGATGGCGTTCATTTATCTTTAGATGTTGATGCTTTAGATCCGCTTGAAACGCCAGGC
ACTGGTACTAGAGTTTTGGGTGGTCTTAGTTATAGAGAAAGCCATTTTGCATTGGAATTACTGCATCAATCACATTTAAT
TTCCTCAATGGATTTAGTTGAAGTAAATCCATTGATTGACAGTAATAATCATACTGCTGAACAAGCGGTTTCATTAGTTG
GAACATTTTTTGGTGAAACTTTATTATAA

Upstream 100 bases:

>100_bases
TATGAAGTAATAAGATAAACAGATTATATGTGTAGCTATTGCTTGATAATGGTAAGCGCATACATTATTCTTTAATTACA
TAGAGCAAAGGGGGACGCTT

Downstream 100 bases:

>100_bases
ATAAATGATTTGTAGTGTATAAAGTATATTTTGCTTTTTGCACTACTTTTTTTAATTCACTAAAATGATTAAGAGTAGTT
ATAATCTTTAAAATAAATTT

Product: arginase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 302; Mature: 301

Protein sequence:

>302_residues
MTKTKAIDIIGAPSTFGQRKLGVDLGPTAIRYAGLISRLKQLDLDVYDKGDIKVPAVNIEKFHSEQKGLRNYDEIIDVNQ
KLNKEVSASIENNRFPLVLGGDHSIAVGSVSAISKHYNNLGVIWYDAHGDLNIPEESPSGNIHGMPLRILTGEGPKELLE
LNSNVIKPENIVLIGMRDLDKGERQFIKDHNIKTFTMSDIDKLGIKEVIENTIEYLKSRNVDGVHLSLDVDALDPLETPG
TGTRVLGGLSYRESHFALELLHQSHLISSMDLVEVNPLIDSNNHTAEQAVSLVGTFFGETLL

Sequences:

>Translated_302_residues
MTKTKAIDIIGAPSTFGQRKLGVDLGPTAIRYAGLISRLKQLDLDVYDKGDIKVPAVNIEKFHSEQKGLRNYDEIIDVNQ
KLNKEVSASIENNRFPLVLGGDHSIAVGSVSAISKHYNNLGVIWYDAHGDLNIPEESPSGNIHGMPLRILTGEGPKELLE
LNSNVIKPENIVLIGMRDLDKGERQFIKDHNIKTFTMSDIDKLGIKEVIENTIEYLKSRNVDGVHLSLDVDALDPLETPG
TGTRVLGGLSYRESHFALELLHQSHLISSMDLVEVNPLIDSNNHTAEQAVSLVGTFFGETLL
>Mature_301_residues
TKTKAIDIIGAPSTFGQRKLGVDLGPTAIRYAGLISRLKQLDLDVYDKGDIKVPAVNIEKFHSEQKGLRNYDEIIDVNQK
LNKEVSASIENNRFPLVLGGDHSIAVGSVSAISKHYNNLGVIWYDAHGDLNIPEESPSGNIHGMPLRILTGEGPKELLEL
NSNVIKPENIVLIGMRDLDKGERQFIKDHNIKTFTMSDIDKLGIKEVIENTIEYLKSRNVDGVHLSLDVDALDPLETPGT
GTRVLGGLSYRESHFALELLHQSHLISSMDLVEVNPLIDSNNHTAEQAVSLVGTFFGETLL

Specific function: Catalyzes The Formation Of Putrescine From Agmatine. [C]

COG id: COG0010

COG function: function code E; Arginase/agmatinase/formimionoglutamate hydrolase, arginase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the arginase family

Homologues:

Organism=Homo sapiens, GI10947139, Length=306, Percent_Identity=40.1960784313725, Blast_Score=222, Evalue=4e-58,
Organism=Homo sapiens, GI4502215, Length=304, Percent_Identity=39.1447368421053, Blast_Score=219, Evalue=2e-57,
Organism=Homo sapiens, GI37537722, Length=298, Percent_Identity=27.1812080536913, Blast_Score=75, Evalue=5e-14,
Organism=Escherichia coli, GI1789306, Length=208, Percent_Identity=27.8846153846154, Blast_Score=69, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI71996843, Length=296, Percent_Identity=31.4189189189189, Blast_Score=137, Evalue=8e-33,
Organism=Saccharomyces cerevisiae, GI6325146, Length=329, Percent_Identity=34.6504559270517, Blast_Score=180, Evalue=2e-46,
Organism=Drosophila melanogaster, GI24638886, Length=309, Percent_Identity=34.3042071197411, Blast_Score=170, Evalue=1e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ARGI_STAAC (P60086)

Other databases:

- EMBL:   Y09927
- EMBL:   Y09594
- EMBL:   CP000046
- RefSeq:   YP_186967.1
- ProteinModelPortal:   P60086
- SMR:   P60086
- STRING:   P60086
- EnsemblBacteria:   EBSTAT00000009789
- GeneID:   3237431
- GenomeReviews:   CP000046_GR
- KEGG:   sac:SACOL2154
- TIGR:   SACOL2154
- eggNOG:   COG0010
- GeneTree:   EBGT00050000025100
- HOGENOM:   HBG391953
- OMA:   ADIPNDS
- ProtClustDB:   CLSK885803
- BioCyc:   SAUR93062:SACOL2154-MONOMER
- InterPro:   IPR014033
- InterPro:   IPR006035
- InterPro:   IPR020855
- Gene3D:   G3DSA:3.40.800.10
- PANTHER:   PTHR11358:SF2
- PANTHER:   PTHR11358
- PRINTS:   PR00116
- TIGRFAMs:   TIGR01229

Pfam domain/function: PF00491 Arginase

EC number: =3.5.3.1

Molecular weight: Translated: 33265; Mature: 33134

Theoretical pI: Translated: 5.21; Mature: 5.21

Prosite motif: PS01053 ARGINASE_1; PS51409 ARGINASE_2; PS00147 ARGINASE_1 ; PS00148 ARGINASE_2

Important sites: BINDING 180-180 BINDING 274-274

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKTKAIDIIGAPSTFGQRKLGVDLGPTAIRYAGLISRLKQLDLDVYDKGDIKVPAVNIE
CCCCEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEECCCCEEEEEECHH
KFHSEQKGLRNYDEIIDVNQKLNKEVSASIENNRFPLVLGGDHSIAVGSVSAISKHYNNL
HHHHHHHHCCCHHHHHHHHHHHCHHHHHHCCCCCEEEEECCCCCEEECHHHHHHHHHCCE
GVIWYDAHGDLNIPEESPSGNIHGMPLRILTGEGPKELLELNSNVIKPENIVLIGMRDLD
EEEEEECCCCCCCCCCCCCCCCCCCEEEEEECCCHHHHHHHCCCCCCCCCEEEEEECCCC
KGERQFIKDHNIKTFTMSDIDKLGIKEVIENTIEYLKSRNVDGVHLSLDVDALDPLETPG
CHHHHHHHHCCEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCC
TGTRVLGGLSYRESHFALELLHQSHLISSMDLVEVNPLIDSNNHTAEQAVSLVGTFFGET
CCHHHHCCCCCCHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHH
LL
CC
>Mature Secondary Structure 
TKTKAIDIIGAPSTFGQRKLGVDLGPTAIRYAGLISRLKQLDLDVYDKGDIKVPAVNIE
CCCEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEECCCCEEEEEECHH
KFHSEQKGLRNYDEIIDVNQKLNKEVSASIENNRFPLVLGGDHSIAVGSVSAISKHYNNL
HHHHHHHHCCCHHHHHHHHHHHCHHHHHHCCCCCEEEEECCCCCEEECHHHHHHHHHCCE
GVIWYDAHGDLNIPEESPSGNIHGMPLRILTGEGPKELLELNSNVIKPENIVLIGMRDLD
EEEEEECCCCCCCCCCCCCCCCCCCEEEEEECCCHHHHHHHCCCCCCCCCEEEEEECCCC
KGERQFIKDHNIKTFTMSDIDKLGIKEVIENTIEYLKSRNVDGVHLSLDVDALDPLETPG
CHHHHHHHHCCEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCC
TGTRVLGGLSYRESHFALELLHQSHLISSMDLVEVNPLIDSNNHTAEQAVSLVGTFFGET
CCHHHHCCCCCCHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHH
LL
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10332717