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The map label for this gene is gcvH [C]

Identifier: 15923314

GI number: 15923314

Start: 371168

End: 371500

Strand: Direct

Name: gcvH [C]

Synonym: SAV0324

Alternate gene names: 15923314

Gene position: 371168-371500 (Clockwise)

Preceding gene: 15923313

Following gene: 15923315

Centisome position: 12.89

GC content: 36.34

Gene sequence:

>333_bases
ATGAAAAAGTTAGCCAATTATTTATGGGTAGAAAAAGTAGGAGATTTGTATGTGTTTAGTATGACACCTGAATTGCAAGA
TGATATTGGGACAGTAGGTTATGTTGAATTCGTAAGTCCAGATGAAGTTAAAGTGGATGATGAAATTGTGAGTATCGAAG
CATCGAAAACGGTCATTGATGTGCAAACGCCATTGTCAGGAACGATTATTGAGCGAAATACAAAAGCGGAAGAAGAACCG
ACAATTTTAAACTCTGAAAAACCAGAAGAAAATTGGTTGTTCAAATTGGATGATGTCGATAAAGAAGCATTCCTAGCATT
ACCGGAGGCTTAA

Upstream 100 bases:

>100_bases
ACCGCTTATTCCAGGTATTGAACAGCGTTGTAAAACATTAAAATTACTCGCGGAAATTTATTTGTAGCATTTTAAATAGA
AGAGAAAGGATGAAGATAAG

Downstream 100 bases:

>100_bases
ATGGAAACGTTAAAATCAAATAAAGCGAGACTTGAATATTTAATCAATGATATGCGTCGAGAGAGAAATGACAATGACGT
ATTGGTAATGCCATCTTCAT

Product: putative glycine cleavage system H protein

Products: Proton; NADH; NH3; CO2; 5,10-methylene-THF [C]

Alternate protein names: GcvH Family Protein

Number of amino acids: Translated: 110; Mature: 110

Protein sequence:

>110_residues
MKKLANYLWVEKVGDLYVFSMTPELQDDIGTVGYVEFVSPDEVKVDDEIVSIEASKTVIDVQTPLSGTIIERNTKAEEEP
TILNSEKPEENWLFKLDDVDKEAFLALPEA

Sequences:

>Translated_110_residues
MKKLANYLWVEKVGDLYVFSMTPELQDDIGTVGYVEFVSPDEVKVDDEIVSIEASKTVIDVQTPLSGTIIERNTKAEEEP
TILNSEKPEENWLFKLDDVDKEAFLALPEA
>Mature_110_residues
MKKLANYLWVEKVGDLYVFSMTPELQDDIGTVGYVEFVSPDEVKVDDEIVSIEASKTVIDVQTPLSGTIIERNTKAEEEP
TILNSEKPEENWLFKLDDVDKEAFLALPEA

Specific function: The Glycine Cleavage System Catalyzes The Degradation Of Glycine. The H Protein Shuttles The Methylamine Group Of Glycine From The P Protein To The T Protein. [C]

COG id: COG0509

COG function: function code E; Glycine cleavage system H protein (lipoate-binding)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Drosophila melanogaster, GI17865652, Length=91, Percent_Identity=36.2637362637363, Blast_Score=63, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 12422; Mature: 12422

Theoretical pI: Translated: 3.87; Mature: 3.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKLANYLWVEKVGDLYVFSMTPELQDDIGTVGYVEFVSPDEVKVDDEIVSIEASKTVID
CCHHHHHHHHCCCCCEEEEEECCCCCCCCCCEEEEEEECCCCEEECCEEEEEECCCEEEE
VQTPLSGTIIERNTKAEEEPTILNSEKPEENWLFKLDDVDKEAFLALPEA
EECCCCCEEEECCCCCCCCCCCCCCCCCCCCCEEEECCCCCCEEEECCCC
>Mature Secondary Structure
MKKLANYLWVEKVGDLYVFSMTPELQDDIGTVGYVEFVSPDEVKVDDEIVSIEASKTVID
CCHHHHHHHHCCCCCEEEEEECCCCCCCCCCEEEEEEECCCCEEECCEEEEEECCCEEEE
VQTPLSGTIIERNTKAEEEPTILNSEKPEENWLFKLDDVDKEAFLALPEA
EECCCCCEEEECCCCCCCCCCCCCCCCCCCCCEEEECCCCCCEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: Lipoyl Cofactor. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NAD; L-glycine; THF [C]

Specific reaction: NAD + L-glycine + THF = Proton + NADH + NH3 + CO2 + 5,10-methylene-THF [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA