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The map label for this gene is 15899167

Identifier: 15899167

GI number: 15899167

Start: 2195006

End: 2196502

Strand: Reverse

Name: 15899167

Synonym: SSO2415

Alternate gene names: NA

Gene position: 2196502-2195006 (Counterclockwise)

Preceding gene: 15899170

Following gene: 15899166

Centisome position: 73.41

GC content: 36.07

Gene sequence:

>1497_bases
GTGAAAGTATTAGTAGTAACTGGAACTTTAGCTGCACCAATACTTTCTGAAGTTGCTAAAAACATTAAAGATACTAAAGT
TGAGATTAAGGTACTTAATTACCCTGTTGCCTCATTAATGAGTACAAAGTTTATAGCAGAAAACTTGAAGCAGACCAAAT
TTGATGCAGATTACATCCTTTTACCAGGTTTAGTCTATGGCGACGCCAAAATTGTTGAGGAAGTTACGGGAGTGAGAACT
TTTAAAGGGACAGAGGAAGCATGGGATCTCCCTAGAGTAATTGAGGCATTGAAAAATGGGATACAACTCTCCACAACGGA
ATCTGCTGATAAGATCATAGGTAAAATGGATAATATTGAAGAGAAGCTAAGAAAAATGGAGGAAGAAGCTAAGATTTCGT
TTGAAATAAATGGAATTAAGATTACAACTTATCCACCGCCATTTAGAATTTTCTTGGAAATAGACAATAAGCAAGAATTC
GAGAAATTGGATAGAATAAGAAAAAACGTTGACGTAGTAGTATTAGGTTTTCCAGTGGGTCACTACGATTTGGACGAGGT
TAAAAATAAGGTTAAACAATTAGTGGACTACGGTTACGTTGTTGGAATAGATGCTGAATCGCCCAGAGAATTAAAAGAAG
GTGTAAGAGCTGGAGCTTCATTCGTATTTAACCTAAATGAAAATAACTTTGAGGAACTTGAGGAAATTAGGAAAGAAGCA
GCATTTGTTGTAGCCCCGTTTAACACTGAAAATAGAGGAGAAATAACTATTGATCTCGTAAAAAAAGCCAAACAAAAAGG
ATTCGATAAATTAATAGCAGATCCCGTATTATCGCCTCCCCTAAGAGGGTTAGTAAGCAGTATAATTGGGTATAAGTACG
TCAGAGAGACGTTGCAAGATATACCTATTCTAATGGGAATTCTTAACGTGACTGAACTCATTGATGCAGATAGTATAGGA
ATGAATGCACTACTAACCGCAATTGCTGGAGAGTTGGGAATTTCTAACTTATTAATTATGGAAAAGGGGAAAACGAGGTG
GAGTAGTTGGGAAGTATCACAAGCTACAAAAATGATAAGTGTAGCTTTGAAGGAAAATAGACTTCCCAAAGATATAGGAA
TAGATTTGTTAGTACTTAAGGATAAGAGAAGATTTAGGGAGAGTTTTAACGCTGACGTGATTGTTAATAGGCGTATAGAG
CCTGAAATGGATAATACCGGATTTGCAAAAATTTTCGTGAGTGAAGATGGATTTGGAGTAGAATGGATTGGGAAAAACAA
GATAACAATAAAAGGAAAAGATGGGCTAAGCATTGGCAGAGAGCTGATTAGGAGAGTTAAGGATATTAGCAAAGAGCATG
CCGTGTATATAGGATATGAGTTGGCCAAGGCTGAGATTGCGTATCAACTTGATAAAAATTATATTCAAGACAAGCCATTG
TTCAAAAAGATAATTAATGATAATCTCCATACCGAGCACGATAAGAAAAGAGGTTAA

Upstream 100 bases:

>100_bases
AAGACTCACAACTATACTATATTACTAAATAATTTTTAAGAGTTTTGTTCAACGATTCTAAAAACGTGAAATTAAATACC
GTAAAAACTAGAATAAATGT

Downstream 100 bases:

>100_bases
CGATTTTACGTTTGTCTTCAGTGTAATTCCGCCGATAATTACGCTAAAGAATGCAGATGAAGACGTAAAGGAATTTCTCT
TACAATTGTCTAAATCTTTT

Product: dihydropteroate synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 498; Mature: 498

Protein sequence:

>498_residues
MKVLVVTGTLAAPILSEVAKNIKDTKVEIKVLNYPVASLMSTKFIAENLKQTKFDADYILLPGLVYGDAKIVEEVTGVRT
FKGTEEAWDLPRVIEALKNGIQLSTTESADKIIGKMDNIEEKLRKMEEEAKISFEINGIKITTYPPPFRIFLEIDNKQEF
EKLDRIRKNVDVVVLGFPVGHYDLDEVKNKVKQLVDYGYVVGIDAESPRELKEGVRAGASFVFNLNENNFEELEEIRKEA
AFVVAPFNTENRGEITIDLVKKAKQKGFDKLIADPVLSPPLRGLVSSIIGYKYVRETLQDIPILMGILNVTELIDADSIG
MNALLTAIAGELGISNLLIMEKGKTRWSSWEVSQATKMISVALKENRLPKDIGIDLLVLKDKRRFRESFNADVIVNRRIE
PEMDNTGFAKIFVSEDGFGVEWIGKNKITIKGKDGLSIGRELIRRVKDISKEHAVYIGYELAKAEIAYQLDKNYIQDKPL
FKKIINDNLHTEHDKKRG

Sequences:

>Translated_498_residues
MKVLVVTGTLAAPILSEVAKNIKDTKVEIKVLNYPVASLMSTKFIAENLKQTKFDADYILLPGLVYGDAKIVEEVTGVRT
FKGTEEAWDLPRVIEALKNGIQLSTTESADKIIGKMDNIEEKLRKMEEEAKISFEINGIKITTYPPPFRIFLEIDNKQEF
EKLDRIRKNVDVVVLGFPVGHYDLDEVKNKVKQLVDYGYVVGIDAESPRELKEGVRAGASFVFNLNENNFEELEEIRKEA
AFVVAPFNTENRGEITIDLVKKAKQKGFDKLIADPVLSPPLRGLVSSIIGYKYVRETLQDIPILMGILNVTELIDADSIG
MNALLTAIAGELGISNLLIMEKGKTRWSSWEVSQATKMISVALKENRLPKDIGIDLLVLKDKRRFRESFNADVIVNRRIE
PEMDNTGFAKIFVSEDGFGVEWIGKNKITIKGKDGLSIGRELIRRVKDISKEHAVYIGYELAKAEIAYQLDKNYIQDKPL
FKKIINDNLHTEHDKKRG
>Mature_498_residues
MKVLVVTGTLAAPILSEVAKNIKDTKVEIKVLNYPVASLMSTKFIAENLKQTKFDADYILLPGLVYGDAKIVEEVTGVRT
FKGTEEAWDLPRVIEALKNGIQLSTTESADKIIGKMDNIEEKLRKMEEEAKISFEINGIKITTYPPPFRIFLEIDNKQEF
EKLDRIRKNVDVVVLGFPVGHYDLDEVKNKVKQLVDYGYVVGIDAESPRELKEGVRAGASFVFNLNENNFEELEEIRKEA
AFVVAPFNTENRGEITIDLVKKAKQKGFDKLIADPVLSPPLRGLVSSIIGYKYVRETLQDIPILMGILNVTELIDADSIG
MNALLTAIAGELGISNLLIMEKGKTRWSSWEVSQATKMISVALKENRLPKDIGIDLLVLKDKRRFRESFNADVIVNRRIE
PEMDNTGFAKIFVSEDGFGVEWIGKNKITIKGKDGLSIGRELIRRVKDISKEHAVYIGYELAKAEIAYQLDKNYIQDKPL
FKKIINDNLHTEHDKKRG

Specific function: Unknown. Does not possess dihydropteroate synthase (DHPS) activity since it does not catalyze the condensation of 6- hydroxymethyl-7,8-dihydropterin pyrophosphate (DHPP) and 4- aminobenzoate to form 7,8-dihydropteroate [H]

COG id: COG0294

COG function: function code H; Dihydropteroate synthase and related enzymes

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 pterin-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005236
- InterPro:   IPR011005
- InterPro:   IPR000489 [H]

Pfam domain/function: PF00809 Pterin_bind [H]

EC number: NA

Molecular weight: Translated: 56176; Mature: 56176

Theoretical pI: Translated: 6.26; Mature: 6.26

Prosite motif: PS50972 PTERIN_BINDING

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVLVVTGTLAAPILSEVAKNIKDTKVEIKVLNYPVASLMSTKFIAENLKQTKFDADYIL
CEEEEEECCHHHHHHHHHHHCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHCCCCCEEE
LPGLVYGDAKIVEEVTGVRTFKGTEEAWDLPRVIEALKNGIQLSTTESADKIIGKMDNIE
ECCEEECCHHHHHHHHCCCCCCCCHHHCCHHHHHHHHHCCCEEEECCHHHHHHHHHHHHH
EKLRKMEEEAKISFEINGIKITTYPPPFRIFLEIDNKQEFEKLDRIRKNVDVVVLGFPVG
HHHHHHHHHCEEEEEEEEEEEEECCCCEEEEEEECCHHHHHHHHHHHCCCCEEEEECCCC
HYDLDEVKNKVKQLVDYGYVVGIDAESPRELKEGVRAGASFVFNLNENNFEELEEIRKEA
CCCHHHHHHHHHHHHHCCEEEEECCCCHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHCC
AFVVAPFNTENRGEITIDLVKKAKQKGFDKLIADPVLSPPLRGLVSSIIGYKYVRETLQD
EEEEEECCCCCCCCEEHHHHHHHHHCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHH
IPILMGILNVTELIDADSIGMNALLTAIAGELGISNLLIMEKGKTRWSSWEVSQATKMIS
HHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCHHHHHHHHH
VALKENRLPKDIGIDLLVLKDKRRFRESFNADVIVNRRIEPEMDNTGFAKIFVSEDGFGV
HHHHHCCCCHHHCCEEEEECCHHHHHHCCCCCEEEECCCCCCCCCCCEEEEEECCCCCCE
EWIGKNKITIKGKDGLSIGRELIRRVKDISKEHAVYIGYELAKAEIAYQLDKNYIQDKPL
EEECCCEEEEECCCCHHHHHHHHHHHHHCCCCCEEEEEEEHHHHHHHHHHHHHHCCCCHH
FKKIINDNLHTEHDKKRG
HHHHHCCCCCCCCCCCCC
>Mature Secondary Structure
MKVLVVTGTLAAPILSEVAKNIKDTKVEIKVLNYPVASLMSTKFIAENLKQTKFDADYIL
CEEEEEECCHHHHHHHHHHHCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHCCCCCEEE
LPGLVYGDAKIVEEVTGVRTFKGTEEAWDLPRVIEALKNGIQLSTTESADKIIGKMDNIE
ECCEEECCHHHHHHHHCCCCCCCCHHHCCHHHHHHHHHCCCEEEECCHHHHHHHHHHHHH
EKLRKMEEEAKISFEINGIKITTYPPPFRIFLEIDNKQEFEKLDRIRKNVDVVVLGFPVG
HHHHHHHHHCEEEEEEEEEEEEECCCCEEEEEEECCHHHHHHHHHHHCCCCEEEEECCCC
HYDLDEVKNKVKQLVDYGYVVGIDAESPRELKEGVRAGASFVFNLNENNFEELEEIRKEA
CCCHHHHHHHHHHHHHCCEEEEECCCCHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHCC
AFVVAPFNTENRGEITIDLVKKAKQKGFDKLIADPVLSPPLRGLVSSIIGYKYVRETLQD
EEEEEECCCCCCCCEEHHHHHHHHHCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHH
IPILMGILNVTELIDADSIGMNALLTAIAGELGISNLLIMEKGKTRWSSWEVSQATKMIS
HHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCHHHHHHHHH
VALKENRLPKDIGIDLLVLKDKRRFRESFNADVIVNRRIEPEMDNTGFAKIFVSEDGFGV
HHHHHCCCCHHHCCEEEEECCHHHHHHCCCCCEEEECCCCCCCCCCCEEEEEECCCCCCE
EWIGKNKITIKGKDGLSIGRELIRRVKDISKEHAVYIGYELAKAEIAYQLDKNYIQDKPL
EEECCCEEEEECCCCHHHHHHHHHHHHHCCCCCEEEEEEEHHHHHHHHHHHHHHCCCCHH
FKKIINDNLHTEHDKKRG
HHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]