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The map label for this gene is yleA [C]

Identifier: 15899133

GI number: 15899133

Start: 2167742

End: 2169007

Strand: Reverse

Name: yleA [C]

Synonym: SSO2380

Alternate gene names: 15899133

Gene position: 2169007-2167742 (Counterclockwise)

Preceding gene: 15899141

Following gene: 15899132

Centisome position: 72.49

GC content: 35.07

Gene sequence:

>1266_bases
ATGAAAAACATTTACGTTGAGACATATGGATGTGCACTAAATAGGGCAGATACTTACGTAATGATGACTTTGCTTAAAAG
TGAGGGTTATAATTTTGTAGAAAACCCAGAGAATGCCGATATAATTATACTGAATACTTGTGCAGTAAGACTAGAAACTG
AAGAGAGAATGAAACAAAGAATTAAGGAGTTAAACACGTTATCTAAAAAATTAGTAGTAGCGGGGTGTATGAGTAGTGCA
GAACCAGCTACAGTTCTTTCCATAGCCCCAAATGCATCATTAATAGGTCCCCAATCCGTTGAAAGAATAGTTGATATAGT
AAAATCAGAAGAACGTAAAATAGTTATTGAGGGTGATAGAGCACTTATAACCCCTAGGACCTTTGATGGAAAAATTGCCA
TAATCCCAGTAGCTGATGGATGTGCGGGCAACTGCAGCTTCTGCATAACTAAATTAGCTCGGAGGAAGTTGAGAAGCTAT
CCATTGAGAGAAATAGTTAACGCTGCAAGAGATGCTATACAATCTGGTGCTAGAGAAATAGAATTGACTGGTCAAGATAC
TGCAGCCTATGGATTAGATTTAGGGGGATCTATAAGTTTAGTTGATGTAGTAAATAAAGTAGCGGATATAGATGGAGACT
TCATGATAAGGATAGGCATGATGACACCAGAACAAGCTATGAGGATAATGGATGATCTAATAGAAGCTATAAGAAACCCA
AAGGTATATAAGTTCATACATTTACCCGTCCAAAGTGGAGATGATAGAGTATTAAAACTAATGAACAGAAAATATACTGT
AGATGAATATAAAGAGTTGATAAGTGAAATAAGACATAAAATACCATTTGTTAACATAACCACGGATATAATTGTAGGCC
ACCCCGGAGAAGATGAAGAGGCATTTAATAACACGTTATTGCTTATGAAGGAATTAAGATTTGAAAGAATACACCTAGCA
ATGTACTCCATAAGGCCAAATACTAGAAGTGCGTCAATGCCTCAAGTTCCAGATAGTATAAAGAAAAAGAGAATTCAAAT
AGCTAATAAACTATATGAGGATCTTGCATTATCTATTCATTTAGATTATGTAGGAAGTACTAGTAGAGTTATTACAACAG
AATTAGGTCGTAAGGGATCAGTGATAGGAAGATTAATGAATTACATCCCAGTTGTGATTAGATCTGAAAATGTAGAATTA
GGAAAATGGTATGATGTTAAAATAACTGAAGCATCATTCTATGATTTGCGTGGGATTCTTGCTTAA

Upstream 100 bases:

>100_bases
GTAATTTCGAGTATAGCCTATCAAGCATTTCTACGTATTCTTTTTCTGAACTCACATTAAACCTATAAGCAAATAGGGTT
TAAAATACTATTGAAGAATA

Downstream 100 bases:

>100_bases
AAAATTTAAACCCTATAGAGGAATGTATATTCAGTATGCCCGAAAGTGTATATATTGCATCGGCTGTTAGAACGCCTATT
GGAAAGTTTGGCGGTGCTTT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 421; Mature: 421

Protein sequence:

>421_residues
MKNIYVETYGCALNRADTYVMMTLLKSEGYNFVENPENADIIILNTCAVRLETEERMKQRIKELNTLSKKLVVAGCMSSA
EPATVLSIAPNASLIGPQSVERIVDIVKSEERKIVIEGDRALITPRTFDGKIAIIPVADGCAGNCSFCITKLARRKLRSY
PLREIVNAARDAIQSGAREIELTGQDTAAYGLDLGGSISLVDVVNKVADIDGDFMIRIGMMTPEQAMRIMDDLIEAIRNP
KVYKFIHLPVQSGDDRVLKLMNRKYTVDEYKELISEIRHKIPFVNITTDIIVGHPGEDEEAFNNTLLLMKELRFERIHLA
MYSIRPNTRSASMPQVPDSIKKKRIQIANKLYEDLALSIHLDYVGSTSRVITTELGRKGSVIGRLMNYIPVVIRSENVEL
GKWYDVKITEASFYDLRGILA

Sequences:

>Translated_421_residues
MKNIYVETYGCALNRADTYVMMTLLKSEGYNFVENPENADIIILNTCAVRLETEERMKQRIKELNTLSKKLVVAGCMSSA
EPATVLSIAPNASLIGPQSVERIVDIVKSEERKIVIEGDRALITPRTFDGKIAIIPVADGCAGNCSFCITKLARRKLRSY
PLREIVNAARDAIQSGAREIELTGQDTAAYGLDLGGSISLVDVVNKVADIDGDFMIRIGMMTPEQAMRIMDDLIEAIRNP
KVYKFIHLPVQSGDDRVLKLMNRKYTVDEYKELISEIRHKIPFVNITTDIIVGHPGEDEEAFNNTLLLMKELRFERIHLA
MYSIRPNTRSASMPQVPDSIKKKRIQIANKLYEDLALSIHLDYVGSTSRVITTELGRKGSVIGRLMNYIPVVIRSENVEL
GKWYDVKITEASFYDLRGILA
>Mature_421_residues
MKNIYVETYGCALNRADTYVMMTLLKSEGYNFVENPENADIIILNTCAVRLETEERMKQRIKELNTLSKKLVVAGCMSSA
EPATVLSIAPNASLIGPQSVERIVDIVKSEERKIVIEGDRALITPRTFDGKIAIIPVADGCAGNCSFCITKLARRKLRSY
PLREIVNAARDAIQSGAREIELTGQDTAAYGLDLGGSISLVDVVNKVADIDGDFMIRIGMMTPEQAMRIMDDLIEAIRNP
KVYKFIHLPVQSGDDRVLKLMNRKYTVDEYKELISEIRHKIPFVNITTDIIVGHPGEDEEAFNNTLLLMKELRFERIHLA
MYSIRPNTRSASMPQVPDSIKKKRIQIANKLYEDLALSIHLDYVGSTSRVITTELGRKGSVIGRLMNYIPVVIRSENVEL
GKWYDVKITEASFYDLRGILA

Specific function: Unknown

COG id: COG0621

COG function: function code J; 2-methylthioadenine synthetase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 TRAM domain [H]

Homologues:

Organism=Homo sapiens, GI93277076, Length=442, Percent_Identity=30.9954751131222, Blast_Score=239, Evalue=4e-63,
Organism=Homo sapiens, GI28872784, Length=476, Percent_Identity=26.0504201680672, Blast_Score=163, Evalue=2e-40,
Organism=Homo sapiens, GI28872782, Length=476, Percent_Identity=26.0504201680672, Blast_Score=163, Evalue=3e-40,
Organism=Escherichia coli, GI1786882, Length=444, Percent_Identity=31.0810810810811, Blast_Score=212, Evalue=4e-56,
Organism=Escherichia coli, GI1787057, Length=436, Percent_Identity=28.2110091743119, Blast_Score=165, Evalue=4e-42,
Organism=Caenorhabditis elegans, GI71996771, Length=355, Percent_Identity=28.7323943661972, Blast_Score=168, Evalue=4e-42,
Organism=Caenorhabditis elegans, GI17553146, Length=459, Percent_Identity=26.5795206971678, Blast_Score=162, Evalue=4e-40,
Organism=Drosophila melanogaster, GI19922432, Length=432, Percent_Identity=31.9444444444444, Blast_Score=229, Evalue=2e-60,
Organism=Drosophila melanogaster, GI21356207, Length=477, Percent_Identity=27.2536687631027, Blast_Score=170, Evalue=1e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006638
- InterPro:   IPR005839
- InterPro:   IPR020612
- InterPro:   IPR013848
- InterPro:   IPR006466
- InterPro:   IPR007197
- InterPro:   IPR002792 [H]

Pfam domain/function: PF04055 Radical_SAM; PF01938 TRAM; PF00919 UPF0004 [H]

EC number: NA

Molecular weight: Translated: 47264; Mature: 47264

Theoretical pI: Translated: 7.42; Mature: 7.42

Prosite motif: PS50926 TRAM

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNIYVETYGCALNRADTYVMMTLLKSEGYNFVENPENADIIILNTCAVRLETEERMKQR
CCCEEEEEECCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCEEEEEEEEEEECHHHHHHHH
IKELNTLSKKLVVAGCMSSAEPATVLSIAPNASLIGPQSVERIVDIVKSEERKIVIEGDR
HHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHCCCCCEEEEECCE
ALITPRTFDGKIAIIPVADGCAGNCSFCITKLARRKLRSYPLREIVNAARDAIQSGAREI
EEECCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCEEE
ELTGQDTAAYGLDLGGSISLVDVVNKVADIDGDFMIRIGMMTPEQAMRIMDDLIEAIRNP
EECCCCCEEECCCCCCCCHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHHHCCC
KVYKFIHLPVQSGDDRVLKLMNRKYTVDEYKELISEIRHKIPFVNITTDIIVGHPGEDEE
CEEEEEEEECCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHCCEEEEEEEEEEECCCCCHH
AFNNTLLLMKELRFERIHLAMYSIRPNTRSASMPQVPDSIKKKRIQIANKLYEDLALSIH
HHHHHHHHHHHHHHHHEEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHEEEEE
LDYVGSTSRVITTELGRKGSVIGRLMNYIPVVIRSENVELGKWYDVKITEASFYDLRGIL
EEECCCCCEEEEECCCCCCHHHHHHHHHCEEEEECCCCCCCCEEEEEEECCHHHHHHCCC
A
C
>Mature Secondary Structure
MKNIYVETYGCALNRADTYVMMTLLKSEGYNFVENPENADIIILNTCAVRLETEERMKQR
CCCEEEEEECCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCEEEEEEEEEEECHHHHHHHH
IKELNTLSKKLVVAGCMSSAEPATVLSIAPNASLIGPQSVERIVDIVKSEERKIVIEGDR
HHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHCCCCCEEEEECCE
ALITPRTFDGKIAIIPVADGCAGNCSFCITKLARRKLRSYPLREIVNAARDAIQSGAREI
EEECCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCEEE
ELTGQDTAAYGLDLGGSISLVDVVNKVADIDGDFMIRIGMMTPEQAMRIMDDLIEAIRNP
EECCCCCEEECCCCCCCCHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHHHCCC
KVYKFIHLPVQSGDDRVLKLMNRKYTVDEYKELISEIRHKIPFVNITTDIIVGHPGEDEE
CEEEEEEEECCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHCCEEEEEEEEEEECCCCCHH
AFNNTLLLMKELRFERIHLAMYSIRPNTRSASMPQVPDSIKKKRIQIANKLYEDLALSIH
HHHHHHHHHHHHHHHHEEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHEEEEE
LDYVGSTSRVITTELGRKGSVIGRLMNYIPVVIRSENVELGKWYDVKITEASFYDLRGIL
EEECCCCCEEEEECCCCCCHHHHHHHHHCEEEEECCCCCCCCEEEEEEECCHHHHHHCCC
A
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]