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The map label for this gene is cbiC [H]

Identifier: 15899069

GI number: 15899069

Start: 2110381

End: 2111379

Strand: Reverse

Name: cbiC [H]

Synonym: SSO2308

Alternate gene names: 15899069

Gene position: 2111379-2110381 (Counterclockwise)

Preceding gene: 15899070

Following gene: 15899068

Centisome position: 70.56

GC content: 37.44

Gene sequence:

>999_bases
GTGGATAGACAATCCAATACTGCAGTAATATTAATAGGTCATGGTTCGAGGAGAGAAACGTATAATAGTGATATAGAAAA
TATGATAAATTACTTAAAGGAAAAGATCTCATCTCCAATATATTTAACTTACAATGAATTCGCTAAGCCTGATTGGAGAT
CATTACTAAACAATGTCGTAAGAGAGGGATATAGGAGAATAGTCATAGGCTTAGTATTTCTAGGAAGAGGGAATCACGTC
TTTAGAGATATAATGGGAGAGTTAGGAATCCAACGATTAAACAGTTGGGTTGTAAGTAAGATAAGTGGAAAGGAGGTAGA
ACTGTACGTTACTGAACCACTCTCCTCGTCTCCCTTGATTGGATTAGCATTATATTACAGATTAGCCAGAGCCTTGAATG
CACTTCCAACTCTTGAATACACTGAGGATCCTTACGAAATCGAAGAGAGTAGTATGAACTTAATTCTATCGAATCTGGAC
GTTAAGGACGAAAGGGAGAAAAGAATAATTGGTAAGGCCATTTTTGCGTCTGGAAATCCGGAATTAGCCAGATATTTAAA
GCTAACTAATTTAGATGCAGGGATTGAGGCAATAAAAGCTGGAAGTGAAATCGTGGCTGATGTGAAAATGGTTTCTGTAG
GTATAAGATGGAGAAAGGTTACTTGTATGATAGATAATGAGAGAACGAAGGAGTTATCAAAGGAATTAGGAATAACCAGA
GCAGCAGCCGCTATGAGATTATCAATTGGACAAGGTGGTAAGGTAGTAGTTATAGGAAACGCTCCTACTGCACTTATGGA
AACGATTAAATTAGTTAAAGAAGGAATTGATATACCGTTTATAGTAGCAACACCCCCTGGTTTCACTAACGCTAAAGAGT
CAAAGGAGGCGTTAATAGAGACTAAAATTCCATCTGTAGTATTAACTGGAACTTATGGTGGGAGTGGAATAGCAGTGGCG
ATTATTAATGAGATTATCAAAATGGCAATGGAGGGATGA

Upstream 100 bases:

>100_bases
TAGATTCAGTGATAAATGCTAAACTTATATTAGGACTCATAAATGAGCTACGTAGGTGTACATTAACAATCCTTAAATAC
TAGATGGTGAAAGAGAATAT

Downstream 100 bases:

>100_bases
AAATGGGGAGGTTATATATTGTTGGAATCGGACCAGGATCAAAAGAACAAAGGACAATTAAGGCGCAAGAAGTTCTGGAA
AAGTCCAATGTAATAATTGG

Product: bifunctional sirohydrochlorin cobalt chelatase/precorrin-8X methylmutase

Products: hydrogenobyrinate

Alternate protein names: Cobalt-precorrin isomerase; HBA synthase [H]

Number of amino acids: Translated: 332; Mature: 332

Protein sequence:

>332_residues
MDRQSNTAVILIGHGSRRETYNSDIENMINYLKEKISSPIYLTYNEFAKPDWRSLLNNVVREGYRRIVIGLVFLGRGNHV
FRDIMGELGIQRLNSWVVSKISGKEVELYVTEPLSSSPLIGLALYYRLARALNALPTLEYTEDPYEIEESSMNLILSNLD
VKDEREKRIIGKAIFASGNPELARYLKLTNLDAGIEAIKAGSEIVADVKMVSVGIRWRKVTCMIDNERTKELSKELGITR
AAAAMRLSIGQGGKVVVIGNAPTALMETIKLVKEGIDIPFIVATPPGFTNAKESKEALIETKIPSVVLTGTYGGSGIAVA
IINEIIKMAMEG

Sequences:

>Translated_332_residues
MDRQSNTAVILIGHGSRRETYNSDIENMINYLKEKISSPIYLTYNEFAKPDWRSLLNNVVREGYRRIVIGLVFLGRGNHV
FRDIMGELGIQRLNSWVVSKISGKEVELYVTEPLSSSPLIGLALYYRLARALNALPTLEYTEDPYEIEESSMNLILSNLD
VKDEREKRIIGKAIFASGNPELARYLKLTNLDAGIEAIKAGSEIVADVKMVSVGIRWRKVTCMIDNERTKELSKELGITR
AAAAMRLSIGQGGKVVVIGNAPTALMETIKLVKEGIDIPFIVATPPGFTNAKESKEALIETKIPSVVLTGTYGGSGIAVA
IINEIIKMAMEG
>Mature_332_residues
MDRQSNTAVILIGHGSRRETYNSDIENMINYLKEKISSPIYLTYNEFAKPDWRSLLNNVVREGYRRIVIGLVFLGRGNHV
FRDIMGELGIQRLNSWVVSKISGKEVELYVTEPLSSSPLIGLALYYRLARALNALPTLEYTEDPYEIEESSMNLILSNLD
VKDEREKRIIGKAIFASGNPELARYLKLTNLDAGIEAIKAGSEIVADVKMVSVGIRWRKVTCMIDNERTKELSKELGITR
AAAAMRLSIGQGGKVVVIGNAPTALMETIKLVKEGIDIPFIVATPPGFTNAKESKEALIETKIPSVVLTGTYGGSGIAVA
IINEIIKMAMEG

Specific function: Catalyzes the conversion of cobalt-precorrin-8X to cobyrinic acid; a methyl migration reaction during the transformation of cobalt-precorrin-3 to form cobyrinic acid [H]

COG id: COG2082

COG function: function code H; Precorrin isomerase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CobH family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003722 [H]

Pfam domain/function: PF02570 CbiC [H]

EC number: 5.4.1.2

Molecular weight: Translated: 36650; Mature: 36650

Theoretical pI: Translated: 8.33; Mature: 8.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDRQSNTAVILIGHGSRRETYNSDIENMINYLKEKISSPIYLTYNEFAKPDWRSLLNNVV
CCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEHHHCCCHHHHHHHHHH
REGYRRIVIGLVFLGRGNHVFRDIMGELGIQRLNSWVVSKISGKEVELYVTEPLSSSPLI
HHHHHHHHHHHEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCHH
GLALYYRLARALNALPTLEYTEDPYEIEESSMNLILSNLDVKDEREKRIIGKAIFASGNP
HHHHHHHHHHHHHCCCCCCCCCCCCHHHHCCHHEEEECCCCCCHHHHHHHHHHEECCCCH
ELARYLKLTNLDAGIEAIKAGSEIVADVKMVSVGIRWRKVTCMIDNERTKELSKELGITR
HHHHHHHHCCCCHHHHHHHCCHHHHHHHHHEEECEEEEEEEEEECCHHHHHHHHHHCCHH
AAAAMRLSIGQGGKVVVIGNAPTALMETIKLVKEGIDIPFIVATPPGFTNAKESKEALIE
HHHHHEEEECCCCEEEEECCCCHHHHHHHHHHHCCCCCCEEEECCCCCCCCHHHHHHHHH
TKIPSVVLTGTYGGSGIAVAIINEIIKMAMEG
HCCCEEEEEECCCCCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MDRQSNTAVILIGHGSRRETYNSDIENMINYLKEKISSPIYLTYNEFAKPDWRSLLNNVV
CCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEHHHCCCHHHHHHHHHH
REGYRRIVIGLVFLGRGNHVFRDIMGELGIQRLNSWVVSKISGKEVELYVTEPLSSSPLI
HHHHHHHHHHHEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCHH
GLALYYRLARALNALPTLEYTEDPYEIEESSMNLILSNLDVKDEREKRIIGKAIFASGNP
HHHHHHHHHHHHHCCCCCCCCCCCCHHHHCCHHEEEECCCCCCHHHHHHHHHHEECCCCH
ELARYLKLTNLDAGIEAIKAGSEIVADVKMVSVGIRWRKVTCMIDNERTKELSKELGITR
HHHHHHHHCCCCHHHHHHHCCHHHHHHHHHEEECEEEEEEEEEECCHHHHHHHHHHCCHH
AAAAMRLSIGQGGKVVVIGNAPTALMETIKLVKEGIDIPFIVATPPGFTNAKESKEALIE
HHHHHEEEECCCCEEEEECCCCHHHHHHHHHHHCCCCCCEEEECCCCCCCCHHHHHHHHH
TKIPSVVLTGTYGGSGIAVAIINEIIKMAMEG
HCCCEEEEEECCCCCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Precorrin 8X

Specific reaction: precorrin-8X = hydrogenobyrinate

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]