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The map label for this gene is rpiA [H]

Identifier: 15897858

GI number: 15897858

Start: 837100

End: 837783

Strand: Reverse

Name: rpiA [H]

Synonym: SSO0978

Alternate gene names: 15897858

Gene position: 837783-837100 (Counterclockwise)

Preceding gene: 15897859

Following gene: 15897844

Centisome position: 28.0

GC content: 34.36

Gene sequence:

>684_bases
GTGGATCCAAAGGAATTACTAGCAACGTATACTTTGAACTATCTAAGAGGAAAAAAGATAATAGGCGTTGGTACTGGAAA
AACTGTTAAGAAATTGATAGAAGTTTTAAGTAGTGAAGAAAATCTTAAAGAAAGCTCATTATTTGTTGCGAGCTCTATCG
ATACTGAAATCGAATTAAGTAAGCGCGGTTTTAAAGTACTTTCCCTTTTCTCCGCTATTCAACCAGAAATTTACGTCGAT
AGCTTCGATATAGTTACCAAAGACGGTATTATGATAAAGGGTGGAGGAGGTGCCTTGCTTAGGGAAAAACTTTTGGCATA
CTTTTCTAAATACAGAATTTTTATAGGAGAATCTACTAAACTAAAAGACACTAAAGTGATTGATATTCCAATTGAGGTCA
TAAGCGTTGGAGTAAGTTATGTCAAATACAAATTAGAGAAAATGGGATTTACCGTGAAAATAAGGGAGGGAAGCGGTAAA
ATGGGGCCAATTATTTCAGATAATGGAAATGTGATTTTGGACGTTTCTGTTAAAACTGAAAATCTATGCGAGTTTGACAG
AATGATAAAGAATATACCATCAATAGTAGAAACTGGAATTTTCTGCAAGGAATTATATAATAAGATCATATTGGCTAATG
AACAAGGTAGAATTGAAGAAATGGATGCGGGGGACGGGATTTGA

Upstream 100 bases:

>100_bases
TAATTTGTTTATAAATGATGAGCTTCCAGGCTTAGATCGGTGAAGAGGGATGTGCAAACGCTGAGTTAGGTTTTATATTT
ACTTTACTAACCATATACTC

Downstream 100 bases:

>100_bases
ACCCGCGAAGGCCTTCGCCAGCGGATCTCTCACTTAAGGGGTCTTGAGTCCGCCCCCTTTGACCAGCTCGGGCACCCCCG
CACATTTTAAATATAAACTC

Product: ribose 5-phosphate isomerase (rpiA)

Products: NA

Alternate protein names: Phosphoriboisomerase A; PRI [H]

Number of amino acids: Translated: 227; Mature: 227

Protein sequence:

>227_residues
MDPKELLATYTLNYLRGKKIIGVGTGKTVKKLIEVLSSEENLKESSLFVASSIDTEIELSKRGFKVLSLFSAIQPEIYVD
SFDIVTKDGIMIKGGGGALLREKLLAYFSKYRIFIGESTKLKDTKVIDIPIEVISVGVSYVKYKLEKMGFTVKIREGSGK
MGPIISDNGNVILDVSVKTENLCEFDRMIKNIPSIVETGIFCKELYNKIILANEQGRIEEMDAGDGI

Sequences:

>Translated_227_residues
MDPKELLATYTLNYLRGKKIIGVGTGKTVKKLIEVLSSEENLKESSLFVASSIDTEIELSKRGFKVLSLFSAIQPEIYVD
SFDIVTKDGIMIKGGGGALLREKLLAYFSKYRIFIGESTKLKDTKVIDIPIEVISVGVSYVKYKLEKMGFTVKIREGSGK
MGPIISDNGNVILDVSVKTENLCEFDRMIKNIPSIVETGIFCKELYNKIILANEQGRIEEMDAGDGI
>Mature_227_residues
MDPKELLATYTLNYLRGKKIIGVGTGKTVKKLIEVLSSEENLKESSLFVASSIDTEIELSKRGFKVLSLFSAIQPEIYVD
SFDIVTKDGIMIKGGGGALLREKLLAYFSKYRIFIGESTKLKDTKVIDIPIEVISVGVSYVKYKLEKMGFTVKIREGSGK
MGPIISDNGNVILDVSVKTENLCEFDRMIKNIPSIVETGIFCKELYNKIILANEQGRIEEMDAGDGI

Specific function: Nonoxidative branch of the pentose phosphate pathway. [C]

COG id: COG0120

COG function: function code G; Ribose 5-phosphate isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribose 5-phosphate isomerase family [H]

Homologues:

Organism=Homo sapiens, GI94536842, Length=198, Percent_Identity=31.3131313131313, Blast_Score=92, Evalue=4e-19,
Organism=Escherichia coli, GI1789280, Length=215, Percent_Identity=31.6279069767442, Blast_Score=93, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17551758, Length=222, Percent_Identity=30.1801801801802, Blast_Score=87, Evalue=9e-18,
Organism=Saccharomyces cerevisiae, GI6324669, Length=219, Percent_Identity=29.2237442922374, Blast_Score=66, Evalue=4e-12,
Organism=Drosophila melanogaster, GI281364072, Length=195, Percent_Identity=31.2820512820513, Blast_Score=85, Evalue=3e-17,

Paralogues:

None

Copy number: 740 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004788
- InterPro:   IPR020672 [H]

Pfam domain/function: PF06026 Rib_5-P_isom_A [H]

EC number: =5.3.1.6 [H]

Molecular weight: Translated: 25163; Mature: 25163

Theoretical pI: Translated: 6.75; Mature: 6.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDPKELLATYTLNYLRGKKIIGVGTGKTVKKLIEVLSSEENLKESSLFVASSIDTEIELS
CCHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHCCCCCCCHHHEEEEECCCCEEEEC
KRGFKVLSLFSAIQPEIYVDSFDIVTKDGIMIKGGGGALLREKLLAYFSKYRIFIGESTK
CCCHHHHHHHHHHCCEEEECCEEEEECCCEEEECCCCHHHHHHHHHHHHHEEEEECCCCC
LKDTKVIDIPIEVISVGVSYVKYKLEKMGFTVKIREGSGKMGPIISDNGNVILDVSVKTE
CCCCEEEECHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCEEECCCCEEEEEEECCC
NLCEFDRMIKNIPSIVETGIFCKELYNKIILANEQGRIEEMDAGDGI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCEECCCCCCC
>Mature Secondary Structure
MDPKELLATYTLNYLRGKKIIGVGTGKTVKKLIEVLSSEENLKESSLFVASSIDTEIELS
CCHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHCCCCCCCHHHEEEEECCCCEEEEC
KRGFKVLSLFSAIQPEIYVDSFDIVTKDGIMIKGGGGALLREKLLAYFSKYRIFIGESTK
CCCHHHHHHHHHHCCEEEECCEEEEECCCEEEECCCCHHHHHHHHHHHHHEEEEECCCCC
LKDTKVIDIPIEVISVGVSYVKYKLEKMGFTVKIREGSGKMGPIISDNGNVILDVSVKTE
CCCCEEEECHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCEEECCCCEEEEEEECCC
NLCEFDRMIKNIPSIVETGIFCKELYNKIILANEQGRIEEMDAGDGI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11248100 [H]